Clinical and Experimental Pediatrics

Clinical note

Allergy

Complement 4 levels of a 4-year-old girl with angioedema

Soyoung Shin, Yoon Tae Lee, Kyung Yil Lee, Joonhong Park, Jae Ho Lee, Eun Ae Yang

Clin Exp Pediatr. 2020;63(1):30-31. Published online November 8, 2019

DOI: https://doi.org/10.3345/kjp.2019.00241

Original articles

Neonatology (Perinatology)

Effectiveness of various nonpharmacological analgesic methods in newborns

Pancham Kumar, Rakesh Sharma, Sukhdev Rathour, Sunidhi Karol, Mohit Karol

Clin Exp Pediatr. 2020;63(1):25-29. Published online August 16, 2019

Question: Can nonpharmacological methods be used for neonatal pain management.
Finding: Nonpharmacological methods like Sucrose, breastfeeding etc have shown to significantly reduce the pain caused by intramuscular hepatitis B vaccination.
Meaning: Nonpharmacological methods are the safe and cheap potential modalities of analgesia which can be used during mild to moderate pain in newborns.

DOI: https://doi.org/10.3345/kjp.2017.05841

Original Articles

Critical Care Medicine

Comparative validity of microalbuminuria versus clinical mortality scores to predict pediatric intensive care unit outcomes

Shifa Nismath, Suchetha S. Rao, B.S. Baliga, Vaman Kulkarni, Gayatri M. Rao

Clin Exp Pediatr. 2020;63(1):20-24. Published online August 12, 2019

Question: Does microalbuminuria predict mortality in pediatric intensive care unit?
Finding: Positive correlation was found between albumin-creatinine ratio and pediatric intensive care unit stay, organ dysfunction and need of inotropes. Area under the receiver operating characteristic curve for albumin-creatinine ratio was comparable to mortality scores.
Meaning: Microalbuminuria is a good predictor of outcome in pediatric intensive care unit and is comparable with mortality scores.

DOI: https://doi.org/10.3345/kjp.2018.07220

Editorials

Allergy

Hereditary angioedema in childhood

Young Min Ahn

Clin Exp Pediatr. 2020;63(1):18-19. Published online January 15, 2020

DOI: https://doi.org/10.3345/kjp.2019.01165

Neonatology (Perinatology)

Prevention and management of pain in the neonatal intensive care unit

Sung Shin Kim

Clin Exp Pediatr. 2020;63(1):16-17. Published online January 15, 2020

DOI: https://doi.org/10.3345/kjp.2019.01200

Genetics and Metabolism

Considerations for evaluating the effectiveness and long-term outcome of enzyme replacement therapy in Pompe disease

Chong Kun Cheon

Clin Exp Pediatr. 2020;63(1):14-15. Published online August 7, 2019

DOI: https://doi.org/10.3345/kjp.2018.07402

Systematic review and meta-analysis

Psychiatric/Psychology

Association between neonatal jaundice and autism spectrum disorders among children: a meta-analysis

Ensiyeh Jenabi, Saeid Bashirian, Salman Khazaei

Clin Exp Pediatr. 2020;63(1):8-13. Published online November 7, 2019

Autism spectrum disorder is a common neurodevelopmental disorder with an unknown etiology. The correlation between neonatal jaundice and the risk of developing autism spectrum disorder was investigated previously. Some studies showed significant associations, whereas others demonstrated no association. In this meta-analysis, we pooled the results of observational studies to examine the association between neonatal jaundice and the risk of autism...

DOI: https://doi.org/10.3345/kjp.2019.00815

Review article

Pulmonology

High-flow nasal cannula oxygen therapy in children: a clinical review

Ji-Won Kwon

Clin Exp Pediatr. 2020;63(1):3-7. Published online October 28, 2019

High-flow nasal cannula (HFNC) is a relatively safe and effective noninvasive ventilation method that was recently accepted as a treatment option for acute respiratory support before endotracheal intubation or invasive ventilation. The action mechanism of HFNC includes a decrease in nasopharyngeal resistance, washout of dead space, reduction in inflow of ambient air, and an increase in airway pressure. In preterm...

DOI: https://doi.org/10.3345/kjp.2019.00626

Perspective

Other

The long journey toward improving children’s health: from ‘Korean Journal of Pediatrics’ to ‘Clinical and Experimental Pediatrics’

Man Yong Han, Yeong Ho Rha, Chong-Woo Bae, Baik-Lin Eun

Clin Exp Pediatr. 2020;63(1):1-2. Published online January 15, 2020

DOI: https://doi.org/10.3345/kjp.2019.01564

Original Articles

Endocrinology

Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity

Bahar Özcabı, Salih Demirhan, Mesut Akyol, Hatice Öztürkmen Akay, Ayla Güven

Clin Exp Pediatr. 2019;62(12):450-455. Published online October 28, 2019

Background: Lipid accumulation product (LAP) is associated with the presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults. Purpose: Here we evaluated the ability of LAP to predict NAFLD in obese children. Methods: Eighty obese children (38 girls; age 6–18 years) were included. Anthropometric measurements and biochemical values were obtained from the patients’ medical records. LAP was calculated as [waist...

DOI: https://doi.org/10.3345/kjp.2019.00248

Neonatology (Perinatology)

Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia

Ga Won Jeon, R. Ann Sheldon, Donna M Ferriero

Clin Exp Pediatr. 2019;62(12):444-449. Published online October 18, 2019

Background: Sixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does not offer complete protection. Here, we investigated whether hypoxia-inducible factor (HIF) promotes cell survival and suggested neuroprotective strategies. Purpose: HIF-1α-deficient mice have increased brain injury after neonatal hypoxia-ischemia (HI), and the...

DOI: https://doi.org/10.3345/kjp.2019.00850

Editorials

Nephrology (Genitourinary)

Is there a simple and less invasive way to accurately diagnose acute pyelonephritis?

Seong Heon Kim

Clin Exp Pediatr. 2019;62(12):442-443. Published online November 19, 2019

DOI: https://doi.org/10.3345/kjp.2019.01186

Neonatology (Perinatology)

Practical considerations when administering surfactants to preterm infants with respiratory distress syndrome

Heui Seung Jo

Clin Exp Pediatr. 2019;62(12):440-441. Published online August 16, 2019

DOI: https://doi.org/10.3345/kjp.2019.00374

Eosinophil count and neutrophil-to-lymphocyte count ratio as biomarkers for predicting early-onset neonatal sepsis

Jang Hoon Lee

Clin Exp Pediatr. 2019;62(12):438-439. Published online July 9, 2019

DOI: https://doi.org/10.3345/kjp.2019.00297

Review Article

Nephrology (Genitourinary)

Reconsideration of urine culture for the diagnosis of acute pyelonephritis in children: a new challenging method for diagnosing acute pyelonephritis

Jun Ho Lee, Seonkyeong Rhie

Clin Exp Pediatr. 2019;62(12):433-437. Published online October 18, 2019

Acute pyelonephritis (APN) should be detected and treated as soon as possible to reduce the risk of the development of acquired renal scarring. However, in the medical field, urine culture results are not available or considered when the prompt discrimination of APN is necessary and empirical treatment is started. Furthermore, urine culture cannot discriminate APN among children with febrile urinary...

DOI: https://doi.org/10.3345/kjp.2019.00710

Cited By 35	The 2017 Korean National Growth Charts for children and adolescents: development, improvement, and prospects
Cited By 7	Clinical implications in laboratory parameter values in acute Kawasaki disease for early diagnosis and proper treatment
Cited By 4	A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years
Cited By 4	Diagnostic value of eosinopenia and neutrophil to lymphocyte ratio on early onset neonatal sepsis
Cited By 3	Epilepsy syndromes during the first year of life and the usefulness of an epilepsy gene panel

Topics