Most cited
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Most-cited articles are from the articles published during the last two years (2018 ~ ).
- Review Article
- General Pediatrics
- The 2017 Korean National Growth Charts for children and adolescents: development, improvement, and prospects
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Jae Hyun Kim, Sungha Yun, Seung-sik Hwang, Jung Ok Shim, Hyun Wook Chae, Yeoun Joo Lee, Ji Hyuk Lee, Soon Chul Kim, Dohee Lim, Sei Won Yang, Kyungwon Oh, Jin Soo Moon
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Clin Exp Pediatr. 2018;61(5):135-149. Published online May 28, 2018
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Growth charts are curves or tables that facilitate the visualization of anthropometric parameters, and are widely used as an important indicator when evaluating the growth status of children and adolescents. The latest version of the Korean National Growth Charts released in 2007 has raised concerns regarding the inclusion of data from both breastfed and formula-fed infants, higher body mass index... |
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- Original Articles
- Cardiology
- Clinical implications in laboratory parameter values in acute Kawasaki disease for early diagnosis and proper treatment
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Yu-Mi Seo, Hyun-Mi Kang, Sung-Churl Lee, Jae-Won Yu, Hong-Ryang Kil, Jung-Woo Rhim, Ji-Whan Han, Kyung-Yil Lee
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Clin Exp Pediatr. 2018;61(5):160-166. Published online May 28, 2018
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PurposeThis study aimed to analyse laboratory values according to fever duration, and evaluate the relationship across these values during the acute phase of Kawasaki disease (KD) to aid in the early diagnosis for early-presenting KD and incomplete KD patients.MethodsClinical and laboratory data of patients with KD (n=615) were evaluated according to duration of fever at presentation, and were compared between... |
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- Neonatology (Perinatology)
- Diagnostic value of eosinopenia and neutrophil to lymphocyte ratio on early onset neonatal sepsis
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Rocky Wilar
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Clin Exp Pediatr. 2019;62(6):217-223. Published online October 8, 2018
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Purpose: To determine the diagnostic value of eosinopenia and the neutrophil-to-lymphocyte ratio (NLR) in the diagnosis of early onset neonatal sepsis (EONS).
Methods: This cross-sectional study was conducted in the Neonatology Ward of R.D. Kandou General Hospital Manado between July and October 2017. Samples were obtained from all neonates meeting the inclusion criteria for EONS. Data were encoded using logistic regression... |
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- Case Report
- Neurology
- A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years
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Minsun Kwak, Hye-Ryun Yeh, Mi-Sun Yum, Hyun-Jin Kim, Su Jeong You, Tae-Sung Ko
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Clin Exp Pediatr. 2019;62(3):108-112. Published online September 18, 2018
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Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of 10 years. Interferon-alpha (IFN-α) is a protein that exerts its antiviral activity via enhancement of cellular immune response and is reported to be an effective drug for the treatment of... |
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- Original Articles
- The association between preeclampsia and autism spectrum disorders among children: a meta-analysis
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Ensiyeh Jenabi, Manoochehr Karami, Salman Khazaei, Saeid Bashirian
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Clin Exp Pediatr. 2019;62(4):126-130. Published online December 24, 2018
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Purpose: In this meta-analysis, relevant case-control and cohort studies were pooled to evaluate the association between preeclampsia and the risk of autism spectrum disorders (ASDs) in children.
Methods: A search for relevant studies in major databases, including Web of Science, PubMed, and Scopus, was performed up to May 2018. The odds ratios (ORs) or rate ratios (RRs) with 95% confidence intervals... |
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- Cardiology
- Change of voltage-gated potassium channel 1.7 expressions in monocrotaline-induced pulmonary arterial hypertension rat model
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Hyeryon Lee, Kwan Chang Kim, Young Mi Hong
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Clin Exp Pediatr. 2018;61(9):271-278. Published online September 15, 2018
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Purpose: Abnormal potassium channels expression affects vessel function, including vascular tone and proliferation rate. Diverse potassium channels, including voltage-gated potassium (Kv) channels, are involved in pathological changes of pulmonary arterial hypertension (PAH). Since the role of the Kv1.7 channel in PAH has not been previously studied, we investigated whether Kv1.7 channel expression changes in the lung tissue of a monocrotaline... |
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- Neonatology (Perinatology)
- The impact of a quality improvement effort in reducing admission hypothermia in preterm infants following delivery
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Han Saem Choi, Soon Min Lee, Hoseon Eun, Minsoo Park, Kook-In Park, Ran Namgung
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Clin Exp Pediatr. 2018;61(8):239-244. Published online August 15, 2018
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Purpose: Hypothermia at admission is associated with increased mortality and morbidity in preterm infants. We performed a quality improvement (QI) effort to determine the impact of a decrease in admission hypothermia in preterm infants.
Methods: The study enrolled very low birth weight (VLBW) infants born at Gangnam Severance Hospital between January 2013 and December 2016. This multidisciplinary QI effort included the... |
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- Endocrinology
- Autoimmunity and intestinal colonization by Candida albicans in patients with type 1 diabetes at the time of the diagnosis
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Semra Gürsoy, Tuba Koçkar, Sezen Ugan Atik, Zerrin Önal, Hasan Önal, Erdal Adal
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Clin Exp Pediatr. 2018;61(7):217-220. Published online July 15, 2018
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Purpose: Type 1 diabetes mellitus (T1DM) is a chronic and immune-mediated disease, which is characterized by the progressive destruction of pancreatic beta cells. T1DM precipitates in genetically susceptible individuals through environmental factors. In this study, we aimed to evaluate the impact of autoimmunity and intestinal colonization of Candida albicans on the development of T1DM.
Methods: Forty-two patients newly diagnosed with T1DM... |
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- Changes of the growth plate in children: 3-dimensional magnetic resonance imaging analysis
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Hyung Ho Yun, Hyun-Jung Kim, Min-Sun Jeong, Yun-Sun Choi, Ji-Young Seo
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Clin Exp Pediatr. 2018;61(7):226-230. Published online July 15, 2018
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Purpose: This pilot study assessed changes in the growth plate and growth rates in children during a 6-month period.
Methods: The study included 31 healthy children (17 boys, 14 girls) under evaluation for growth retardation. Height, weight, bone age, insulin like growth factor-1 (IGF-1), and insulin like growth factor binding protein 3 (IGF-BP3) were measured at baseline and after 6 months.... |
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- Infection
- Clinical and laboratory profiles of hospitalized children with acute respiratory virus infection
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Eunjin Choi, Kee-Soo Ha, Dae Jin Song, Jung Hwa Lee, Kwang Chul Lee
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Clin Exp Pediatr. 2018;61(6):180-186. Published online June 25, 2018
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PurposeDespite the availability of molecular methods, identification of the causative virus in children with acute respiratory infections (ARIs) has proven difficult as the same viruses are often detected in asymptomatic children.MethodsMultiplex reverse transcription polymerase chain reaction assays were performed to detect 15 common respiratory viruses in children under 15 years of age who were hospitalized with ARI between January 2013... |
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- Review Article
- Neurology
- Epilepsy syndromes during the first year of life and the usefulness of an epilepsy gene panel
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Eun Hye Lee
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Clin Exp Pediatr. 2018;61(4):101-107. Published online April 23, 2018
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Recent advances in genetics have determined that a number of epilepsy syndromes that occur in the first year of life are associated with genetic etiologies. These syndromes range from benign familial epilepsy syndromes to early-onset epileptic encephalopathies that lead to poor prognoses and severe psychomotor retardation. An early genetic diagnosis can save time and overall cost by reducing the amount... |
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- Neurology
- The clinical characteristics and prognosis of subgaleal hemorrhage in newborn
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Sun Jin Lee, Jin Kyu Kim, Sun Jun Kim
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Clin Exp Pediatr. 2018;61(12):387-391. Published online September 16, 2018
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Purpose: Subgaleal hemorrhage (SGH) is a rare but potentially fatal condition in newborns; however, few studies have reported on this condition. We aimed to identify the clinical characteristics and prognostic factors of SGH.
Methods: We retrospectively reviewed the medical records of 20 neonates diagnosed with SGH between January 2000 and June 2017. Enrolled neonates were clinically diagnosed when they had tender... |
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- Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine
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Gu Hyun Jung, Su Jeong You
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Clin Exp Pediatr. 2019;62(8):312-316. Published online April 11, 2019
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Purpose: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the rate and types of the hematologic side effects of OXC.
Methods: The medical records of 184 patients diagnosed with epilepsy or movement disorder and on OXC monotherapy, at the Department of... |
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- Efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy
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Yuni Yun, Dongsub Kim, Yun-Jeong Lee, Soonhak Kwon, Su-Kyeong Hwang
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Clin Exp Pediatr. 2019;62(7):269-273. Published online December 26, 2018
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Purpose: There is limited data on the use of perampanel in children under 12 years of age. We evaluated the efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy.
Methods: This retrospective observational study was performed in Kyungpook National University Hospital from July 2016 to March 2018. A responder was defined as a... |
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