- Case Report
- Four Cases of Staphylococcal Scalded Skin Syndrome
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Chul Han Park, Yoo Jin Jeong, Won Jung Choi, Sat Byul Park, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2004;47(1):106-110. Published online January 15, 2004
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Staphylococcal scalded skin syndrome is a systemic disease with a clinical spectrum ranging from subcorneal pustules, patterned exfoliation to extensive erosion and peeling of skin by the exfoliative toxin of group II Staphylococcus aureus. This disease occurs mainly in infancy and children below five years and it isn't easy to differentiate from other vesicular diseases clinically, but skin biopsy shows... |
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- Original Article
- Endoscopic Findings of Children with Henoch-Schonlein Purpura
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Dong Hoon Lee, Chul Han Park, Ji Min Park, Geun Soo Park, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2003;46(6):572-575. Published online June 15, 2003
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Purpose : This study was performed to analyze the endoscopic findings in Henoch-Schonlein purpura patients, and to compare the differences in endoscopic findings according to age and gastrointestinal symptoms.
Methods : We examined children with Henoch-Schonlein purpura aged 3 to 15 years between September 1996 and October 2002. The total number studied was 65, consisting of 41 boys and 24... |
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- Case Report
- MRI Finding of a Case of Relapsed Acute Mixed Type
Leukemia with Bone Marrow Necrosis
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Joo Young Park, Euk Park, Seat Byeoul Park, Dong Seok Jeon, Hee Jung Lee, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2002;45(2):256-260. Published online February 15, 2002
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Bone marrow necrosis is a rare complication of a variety of diseases affecting the marrow. The cause and incidence are unknown, and reports of treatment response are rare. We describe a case of relapsed acute mixed type leukemia with bone marrow necrosis. The patient was a 10 year old female diagnosed with acute mixed type leukemia four years ago. She... |
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- Original Article
- Infectious Manifestations in Childhood Leukemia
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Yoon Jung Cho, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2001;44(9):1019-1030. Published online September 15, 2001
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Purpose : Infection is one of the major causes of morbidity and mortality in children during chemotherapy
for leukemia and the development of fever in neutropenic cancer patients frequently indicates
infection. The purpose of the present study is to evaluate infectious manifestations during
the course of leukemia.
Methods : Seventy eight leukemic children who had one or more occasions of infection during
hospitalization from January... |
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- Case Report
- A Case of Relapsed Acute Promyleocytic Leukemia Induced Remission with Arsenic Trioxide(As2O3)
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Jin Hye Park, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2000;43(8):1132-1136. Published online August 15, 2000
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Acute promyelocytic leukemia(APL) is a unique entity in the spectrum of acute myelogenous leukemia. It has several characteristic features, including distinctive morphology, chromosomal translocation, t(15:17), disseminated intravascular coagulation and effect on retinoic acid. Retinoic acid which is a derivative of vitamin A induces differentation of APL cells in vitro and in vivo, but its cessation induces relapse of APL. Arsenic... |
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- A Case of Acute Leukemia Remitted by Adding Cyclosporin-A Previously Failed with Induction Therapy
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Seat Byeoul Park, Byung Kyu Choe, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2000;43(7):988-992. Published online July 15, 2000
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Clinical chemotherapy refractoriness is characterized by resistance to multiple drugs. Multidrug
resistance(MDR) is caused by over-reactivity of a unidirectional drug efflux pump, transmembrane
glycoprotein(P-glycoprotein), which is encoded by the MDR1 gene. P-glycoprotein leads to increased
drug efflux and decreased intracellular drug concentration. Clinical trials that attempt to
reverse or modulate MDR have been done. Cyclosporin-A and verapamil are the most extensively
studied agents and several... |
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- Original Article
- Clinical Manifestation of Childhood Acute Leukemia with Bone Involvement
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Kyoung Eun Jeong, Hee Jung Lee, Kwang Soon Song, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2000;43(6):806-813. Published online June 15, 2000
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Purpose : Bone involvement is known to develop in 40-70% of pediatric acute leukemia. We aimed to analyze the clinical course and result of therapy in pediatric acute leukemia with bone involvement.
Methods : Twenty-seven patients diagnosed as pediatric acute leukemia at Dong San Medical Center from Jan. 1996 to Aug. 1998 were evaluated. According to bone X-ray and whole body... |
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- Original Article
- Anticancer Effect of Arsenic Trioxide in Acute Promyelocytic Leukemia
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Ki Young Song, Jin Hye Park, Yoon Jung Cho, Won Ki Baek, Ki Young Kwon, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 2000;43(3):327-334. Published online March 15, 2000
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Purpose : Acute promyelocytic leukemia(APL or AML, M3) represents an unique model for cancer research in terms of biological and clinical features. Since 1988, it has been widely confirmed that all-trans retinoic acid(ATRA) can induce complete clinical remission in over 85% of APL patients by a differentiation process, with PML-RARα protein possibly being the direct target of ATRA. However, ATRA... |
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- Chemosensitivity Test of Childhood Leukemic Cells
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Tae Woong Ha, Su Kyung Jung, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 1999;42(8):1111-1121. Published online August 15, 1999
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Purpose : The purpose of the present study is to determine the relation between in vitro resistance to 9 drugs, measured with colorimetric methylthiazol tetrazolium(MTT) assay and prognostic factors.
Methods : Thirty children with leukemia were evaluated at the pediatric department of Dongsan Medical Center. All samples tested with the MTT assay contained 80% or more leukemic cells, which were isolated... |
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- Urinary Red Cell Volume in the Diagnosis of Glomerular and Non-Glomerular Heaturia in children
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Jong Sul Kwon, Dong Seok Kim, Myung Sung Kim, Joon Sik Kim, Chin Moo Kang, Dong Seok Jeon
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Clin Exp Pediatr. 1994;37(1):40-46. Published online January 15, 1994
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Hematuria is a important clinical sign that is a consequence of significatn renal, urologic or sytemic disease. Recently the morphology of the red cell in hematuria has been used to indicate a renal or non-renal source and also the measurement of red cell volume by red cell analyzer has been used to distinguish glomerular from non-glomerular hematuria.
In this study, the... |
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- Plasma Norepinephrine Levels in Infants and Children with Congestive Heart Failure
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Sang Woog Lee, Myung Sung Kim, Sang Lak Lee, Tae Chan Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1993;36(7):982-986. Published online July 15, 1993
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To characterize the sympathetic nervous system response to congestive heart failure in infants and children, plasma norepinephrine levels were measured in 29 patients aged 4 months to 15 years undergoing routine cardiac catheterization at Dong San Hospital, Keimyung University during the period of 4 months from November 1990 to February 1991.
Plasma norepinephrine levels were significantly higher in patients with heart... |
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- Case Report
- Two Cases of Gaucher's Disease in Brothers
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Seung Beum Cho, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 1993;36(12):1752-1760. Published online December 15, 1993
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We experienced two cases of Gaucher's disease of adult type in brother aged four years and two years. The patients showed hepatosplenomegaly with anemia and thrombocytopenia. Typical Gaucher cells were found in bone marrow and biopsy specimens of liver and spleen through light and electron microscopic examination. Splenectomy was followed by improvement of anemia and thrombocytopenia.
A brief review of... |
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- Original Article
- Clincal Study on 12 Cases of Neonatal Group B β-Hemolytic Streptococcal Meningitis
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Won Jin Kim, Sang Woog Lee, Sang Lak Lee, Myung Sung Kim, Chin Moo Kang
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Clin Exp Pediatr. 1993;36(11):1507-1515. Published online November 15, 1993
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A clinical study was made on 12 cases of neonatal Group Bβ-hemolytic streptococcal(=GBS)meningitis, who were admitted to the department of Pediatrics, Dong-San Hospital, Keimyung University during the period of 3 years from Aug 1989 to Jul 1992.
The following results were obtained
1) GBS was cultured in 12 cases(57.1%) among 21 neonatal meningitis admitted during the same period.
2) Male and female ratio... |
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- Upper gastrointestinal diseases diagnosed by upper gastrointestinal fiberoptic endoscopy in children.
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Jong Moon Hwang, Pal Dong Kim, Tae Won Paik, Chin Moo Kang
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Clin Exp Pediatr. 1991;34(2):217-222. Published online February 28, 1991
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A clinical analysis was carried out on 83 cases of upper gastrointestinal diseases, diagnosed by
fiberoptic endoscopic examination in children, who had visited the department of pediatrics,
Keimyung University, Dong San Hospital from January 1980 to June 1987.
Following results were obtained:
Out of 83 cases, 61 (73.5%) were between 11-15 years of age and the male to female ratio was 3.
6:1.
The disease distribution... |
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- A case of acute megakaryoblastic leukemia with Down syndrome.
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Sung Jin Chang, Sung Min Sohn, Heung Sik Kim, Chin Moo Kang, Dong Seok Jeon
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Clin Exp Pediatr. 1991;34(12):1730-1735. Published online December 31, 1991
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We experienced a case of acute megakaryoblastic leukemia (M7) with Down syndrome.
The patient was admitted due to premature SGA, which revealed characteristic facial figure of
Down syndrome.
M7 was diagnosed with PB smear which showed abundant megakaryoblast and confirmed by using
the monoclonal antiplatelet glycoprotein IIb/IIIa antibody (J 15). On 25th hospital day, the patient
gained weight but discharged without further treatment of M7.
Authors... |
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- Therapeutic effects of plasmapheresis in Guillian-Barre syndrome.
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Sung Jin Chang, Sun Hee Jung, Eun Sook Suh, Chin Moo Kang
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Clin Exp Pediatr. 1991;34(1):66-73. Published online January 31, 1991
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Although the exact mechanism of the immunologic injury is unknown, the pathogenesis of the
Guillain-Barr受 syndrome is explained as an autoimmune attack directed against to peripheral nervous
myelin. So plasmapheresis is tried for treatment of Guillain-Barr즌 syndrome.
Authors analysed 12 cases af Guillain-Barr受 syndrome who were treated with plasmapheresis and
compared the results with that of the 13 cases, treated with conventional therapy.
Duration between... |
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- Relationship between anaphylactoid purpura and Beta-Hemolytic Streptococcal Infection.
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Ji Eun Lee, Young Sook Kang, Joon Sik Kim, Sung Ho Kim, Chin Moo Kang
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Clin Exp Pediatr. 1990;33(9):1231-1236. Published online September 30, 1990
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Relationship between anaphylactoid purpura and beta-hemolytic streptococcal infection was obser-
ved and analyzed through clinical manifestation and labortory findings in 146 cases of allergic
purpura, hospitalized at Dongsan hospital, Keimyung University during the period from January, 1981
to May, 1987.
The following results were obtained.
1) The age distribution of anaphylactoid purpura showed a peak incidence between 2 to 7 years of
age and male preponderance was... |
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- Vitamin K Dependent Hemorrhagic Disease of the Newborn and Infancy with Intracranial Hemorrhage.
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Ji Eun Lee, Pal Dong Kim, Hong Dae Cha, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 1990;33(9):1209-1215. Published online September 30, 1990
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Eight cases of vitamin K dependent hemorrhagic disease of the newborn and infancy with intra-
cranial hemorrhage were analysed clinically.
Out of 8 cases, 3 cases developed the bleeding within 7 day of life and 5 cases after one month.
Two cases had bleeding before initial feeding. Out of 6 cases who were fed before the onset of
bleeding, 4 cases had breast feeding.
Neurological... |
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- Correlation among Electrocardiographic, Echocardigraphic and Hemodynamic Analysis in Atrial Septal Defect, Ostium Secundum type.
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Soon Jung Lee, Chi Han Kwon, Joon Sik Kim, Tae Chan Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1990;33(7):946-951. Published online July 31, 1990
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The electrocardiographic, echocardiographic and hemodynamic analysis were made on 32 patients
with atrial septal defect of ostium secundum type, who were diagnosed by echocardiography, right
heart catheterization at Dong San Hospital, Keimyung University during the period of 5 years and 6
months from Jaunary 1982 to June 1987.
Following results were obtained.
Out of 32 patients, 14 were male and 18 were female. Their ages... |
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- A Case of Dermatomyositis.
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Pal Dong Kim, Chi Han Kwon, Eun Sook Suh, Chin Moo Kang
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Clin Exp Pediatr. 1990;33(6):870-878. Published online June 30, 1990
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Dermatomyositis is a rarely recognized disorder with poor prognosis. The mortality has been
decreased after the initiation of steroid for ifs treatment. Authors experienced a case of der-
matomyositis responded well to prednisone therapy and developed hyperglycemia laterly.
A 14 year old boy was admitted to pediatric ward with the chief complaints of progressive muscular
weakness and facial rash and diagnosed as having dermatomyositis... |
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- Four Cases of Childhood Systemic Lupus Erythematosus.
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Jun Ah Jeong, Young Mi Kim, Eun Sook Suh, Sung Ho Kim, Chin Moo Kang, Sang Sook Lee, Chai Hong Chung
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Clin Exp Pediatr. 1990;33(2):264-273. Published online February 28, 1990
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Systemic Lupus Erythematosus (SLE) is a rare entity in pediatric age and prognosis is poor due to
higher incidence of renal involvement in children.
Authors experienced four cases of SLE, aged between 9-13 years. All cases were female.
The diagnosis was based on “The 1982 revised criteria for SLE (by American Rheumatism
Association).
All cases had fever on admission and the butterfly facial rash was... |
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- Cytogenetic Analysis of Chromosomal Abnormalities in Children.
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Key Young Song, Kwang Man Kim, Joon Sik Kim, Hong Dae Cha, Heung Sik Kim, Chin Moo Kang
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Clin Exp Pediatr. 1990;33(2):153-161. Published online February 28, 1990
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The present report described the cytogenetic findings in 273 cases under the age of 15 years who
were suspected as having chromosomal abnormalities clinically.
The cytogenetic analysis was conducted at chromosome laboratory of Keimyung University School
of Medicne, from September 1982 to June 1987.
The following results were obtained.
Chromosomal abnormalities were found in 85 (31.3%) of the cases studied.
Of 85 cases, 41 cases (85.9%)... |
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- Clinical Study on Hypernatremic Dehydration in Children.
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Young Mi Kim, Key Young Song, Sung Ho Kim, Tae Chan Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1990;33(2):146-152. Published online February 28, 1990
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The clinical study was done on 68 cases of hypernatremic dehydration which were diagnosed at
pediatric department of Dong-san Hospital Keimyung University during the period from January 1980
to June 1987.
The results were as follows;
1) Among 672 cases with dehydration, hypernatremic dehydration was 10.1%
2) The higer monthly distribution was in May and November.
3) Out of 68 cases, 61 cases (89.7%) were under the 6 months... |
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- A Case of Interrupted Aortic Arch.
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Yeong Sook Kang, Sun Hee Jung, Tae Chan Kwon, Chin Moo Kang, Seok Kil Zeon, Kwang Sook Lee, Yeong Sun Yoo
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Clin Exp Pediatr. 1990;33(11):1579-1585. Published online November 30, 1990
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Interrupted aortic arch is a congenital anomaly in which discontinuity is present between ascending
and descending aorta, and is associated frequently with ventricular septal defect and patent ductus
arteriosus.
Authors experienced a case of interrupted aortic arch in a 4 year old boy associated with a
ventriculalr septal defect and patent ductus arteriosus.
Diagnostic confirmation was made by 2-D echocardiography, cardiac cathetrization and angiogra-
phy.
Direct closure... |
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- The Hemodynamics and Electrocardiogram in Isolated Ventricular Septal Defect.
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Kwang Man Kim, Ki Young Song, Sang Kwon Lee, Tae Chan Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1989;32(8):1098-1105. Published online August 31, 1989
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Ventricular septal defect is the most common cardiac malformation, accounting for 25% of
congenital heart disease.
The electrocardiogram is becoming more useful as a tool in estimating the size of the ventricular
septal defect and the type of pulmonary vascular response.
This report comprises 210 patients in whom the diagnosis of isolated ventricular septal defect was
made by cardiac catheterization and angiocardiography at Dong San... |
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- Abdaninal Tumor in Infants and Children.
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Young Soo Kim, Kwang Man Kim, Seung Ho Kim, Tae Chan Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1989;32(3):366-374. Published online March 31, 1989
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Eighty seven patints with abdominal tumor which were diagnosed with abdominal C-T scan and
confirmed histologically were reviewed. These patients were admitted to pediatric department of
Dong San Medical Canter from January, 1980 to June, 1986.
The results were as follows;
Out of 87 patients, 30 (34.5%) were intraperitoneal and 57 (65.5%) were retroperitoneal tumor.
Among intraperitoneal tumor, 15 cases (50%) were hepatosplenomegaly, and among... |
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- Hydronephrosis in Children.
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Jong Soo Lee, Dong Min Kang, Hong Dae Cha, Seong Ho Kim, Tae Chan Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1988;31(3):322-328. Published online March 31, 1988
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Hydronephrosis is the commonest abdominal tumor in infants and children resulted from urinary
tract obstruction. The urinary tract obstruction has been defined as a disturbance of the normal
pressureflow relationships in the urinary tract and it is only by an increase in pressure that the effects
of obstruction are transmitted back to the kidney.
This report is a clinical study on 47 hydronephrosis under... |
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- Clinical Analysis on Organisms Isolated from Blood Culture.
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Dong Min Kang, Jong Seo Lee, Hong Dae Cha, Tae Chan Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1988;31(1):40-47. Published online January 31, 1988
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This is the report of clinical analysis on 197 organisms isolated from blood culture for 8,385 patients
which were admitted to the Pediatric department of Dong San Hospital, Keimyung University, during
the priod of 3 years from June 1982 to May 1985.
The results were as follows
Out of 197 cases, 81 (41.4%) were above 5 years of age.
Out of 197 cases, 117 (59.4%)... |
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- Clinical, epidemiological, and serological observation on human rotavirus gastroenteritis in infants and children.
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Chin Moo Kang
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Clin Exp Pediatr. 1985;28(2):140-146. Published online February 28, 1985
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The author studied 115 infants with watery diarrhea, admitted to the Pediatric Department of Dorg San Medical Center during the period of 9 months from October 1982 through June 1983 and dsveloped an Enzyme lirked immunosorbent assay to detect human rota virus antigen for all patients and clinical, epidemiologic, and laboratory studies were done. The results were as follows: 1)76... |
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- Case Report
- A Case of Multiple Brain Abscess Complicated to Purulent Meningitis in Newborn.
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Kui Ja Kim, Hye Young Chung, Tae Chan Kwon, Young Dae Kwon, Chin Moo Kang
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Clin Exp Pediatr. 1983;26(7):717-721. Published online July 31, 1983
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This paper presented a case of multiple brain abscesses complicated with meningitis,
found in a 7 days old newborn boy. This baby was admitted with the chief complaints of poor sucking and irritability. Diagnosis of purulent meningitis was made through CSF study.
High fever and abnormal CSF(pleccytcsis and gradually increasing protein level) has been persisted inspite of broad spectrum heavy antibiotic... |
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- Original Article
- Routine Skull Roentgenograms in Management of Infants and Children with Conversions.
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Sin Hyang Kim, Young Keun Kim, In Kee Paik, Chin Moo Kang
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Clin Exp Pediatr. 1981;24(4):352-357. Published online April 15, 1981
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Convulsions are common in childrens and the skull radiogram is often integral part of a routine work up in patients with convulsions. We studied the skull roentgenograms performed as part of the routine work up of the children with convulsions to evaluate our own experience concerning the contribution of routine skull roentgenograms to the diagnosis and the management of convulsions.... |
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- Clinical Observation of Malignant Tumors in Children.
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Jin Oh Chang, Won Ho Choi, In Kee Paick, Chin Moo Kang
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Clin Exp Pediatr. 1981;24(1):63-69. Published online January 15, 1981
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A total 147 cases of malignant tumors in children under 15 years of age who admitted Presbyterian Medical Center, Keimyung University for 6 years from Jan. 1973 to Dec. 1978 were analyzed clinically and the following results were obtained. 1) The incidence of malignancies on all admitted cases was 1.7% and the annual incidence was 1.4~2.0% without any annual increase... |
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- Case Report
- The Cases of Sturge-Weber Disease.
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Jong Woo Suh, Hee Sook Kim, In Kee Paick, Chin Moo Kang, Jip Kim
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Clin Exp Pediatr. 1978;21(6):464-470. Published online June 30, 1978
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Two cases of Sturge-Weber disease in a 10 years old female and a 7 years old male were prese-nted. The diagnosis was established by charactristic features of Sturge-Weber disease including facial port-wine nevus, convulsion, typical ???ailread track pattern intracranial calcifications, some degree of mental retardation and hemiplegia. A brief review of related literature was made. |
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- Original Article
- Hypocalcemia in Infancy.
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Hee Sook Kim, Byung Kil Cheun, Ji Sub Oh, Chin Moo Kang
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Clin Exp Pediatr. 1978;21(12):1138-1146. Published online December 31, 1978
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23 cases of infantile hypocalcemia which were admitted to the pediatric department of Daegy Presbyterian Hospital during the past 2 years from August 1975 throght July 1977 were clinically evaluated. The results were as follows: 1) The age distribution was ranging from one day to six months with 19 cases(82.6%) of newborn under the 1 month of age and sex... |
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- Clinical Review of Miliary Tuberculosis in Children
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In Kee Paick, Kun Hee Park, Ji Sup Oh, Chin Moo Kang
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Clin Exp Pediatr. 1976;19(9):668-675. Published online September 30, 1976
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The following results were obtained through the review conducted among 68 cases of miliary tuberculosis under the age of 15 years at Pediatric Department of Daegu Presbyterian Medical Center during the period of January 1967 through August 1975. 1)There was the increasing incidence of miliary tuberculosis for the last 2~3 years, noting 47% of total patients during of the same... |
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- Case Report
- Recurrent acute Intussusception
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Kun Hee Park, In Kee Paick, Ji Sup Oh, Chin Moo Kang, Jip Kim
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Clin Exp Pediatr. 1976;19(10):722-727. Published online October 31, 1976
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Two cases of recurrent acute intussception in a 11 month old female and a 7 month old male infants who had experienced 8 recurrences were presented. Surgical correction was performed in both cases, followed by 6 recurrences in case I and no recurrence in case I, and no definite etiologic factors, except movable cecum in case I and mesenteric lymphadenopathies... |
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