Journal of the Korean Pediatric Society 1991;34(12):1730-1735.
Published online December 31, 1991.
A case of acute megakaryoblastic leukemia with Down syndrome.
Sung Jin Chang1, Sung Min Sohn1, Heung Sik Kim1, Chin Moo Kang1, Dong Seok Jeon2
1Department of Pediatrics, Keimyung University, School of Medicine, Taegu, Korea
2Department of clinical pathology, Keimyung University, School of Medicine, Taegu, Korea
Down 증후군과 동반된 급성 거핵아구성 백혈병 1례
장성진1, 손성민1, 김흥식1, 강진무1, 전동석2
1계명대학교 의과대학 소아과학교실
2계명대학교 의과대학 임상병리학교실
Received: 23 May 1991   • Accepted: 26 July 1991
Abstract
We experienced a case of acute megakaryoblastic leukemia (M7) with Down syndrome. The patient was admitted due to premature SGA, which revealed characteristic facial figure of Down syndrome. M7 was diagnosed with PB smear which showed abundant megakaryoblast and confirmed by using the monoclonal antiplatelet glycoprotein IIb/IIIa antibody (J 15). On 25th hospital day, the patient gained weight but discharged without further treatment of M7. Authors report the case with review of literature.
Key Words: Acute megakaryoblastic leukemia (M7) Down syndrome


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