Journal of the Korean Pediatric Society 1993;36(7):982-986.
Published online July 15, 1993.
Plasma Norepinephrine Levels in Infants and Children with Congestive Heart Failure
Sang Woog Lee, Myung Sung Kim, Sang Lak Lee, Tae Chan Kwon, Chin Moo Kang
Department of Pediatrics, Keimyung University, School of Medicine, Taegu, Korea
소아 울혈성 심부전증 환자의 혈장 Norepinephrine치의 변동
이상욱, 김명성, 이상락, 권태찬, 강진무
계명대학교 의과대학 소아과학교실
To characterize the sympathetic nervous system response to congestive heart failure in infants and children, plasma norepinephrine levels were measured in 29 patients aged 4 months to 15 years undergoing routine cardiac catheterization at Dong San Hospital, Keimyung University during the period of 4 months from November 1990 to February 1991. Plasma norepinephrine levels were significantly higher in patients with heart disease and congestive heart failure than in those without congestive heart failure (p<0.001). A significant association was found between the level of plasma norepinephrine and severity of the symptoms of congestive heart failure. Plasma norepinephrine levels correlated well with size of the shunt (Qp/Qs) (γ=0.75), degree of pulmonary arterial pressure(γ=0.79) and degree of right ventricular pressure(γ=0.82).
Key Words: Norepinephrine, Congestive heart failure

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