Journal of the Korean Pediatric Society 2002;45(2):256-260.
Published online February 15, 2002.
MRI Finding of a Case of Relapsed Acute Mixed Type Leukemia with Bone Marrow Necrosis
Joo Young Park1, Euk Park1, Seat Byeoul Park1, Dong Seok Jeon2, Hee Jung Lee3, Heung Sik Kim1, Chin Moo Kang1
1Department of Pediatrics, College of Medicine, Keimyung University, Daegu, Korea
2Department of Clinical Pathology, College of Medicine, Keimyung University, Daegu, Korea
3Department of Diagnostic Radiology, College of Medicine, Keimyung University, Daegu, Korea
재발한 급성 혼합형 백혈병에 동반된 골수괴사 1례의 MRI 소견
박주영1, 박억1, 박샛별1, 전동석2, 이희정3, 김흥식1, 강진무1
1계명대학교 의과대학 소아과학교실
2계명대학교 의과대학 임상병리학교실
3계명대학교 의과대학 진단방사선학교실
Correspondence: 
Heung Sik Kim, Email: kimhs@dsmc.or.kr
Abstract
Bone marrow necrosis is a rare complication of a variety of diseases affecting the marrow. The cause and incidence are unknown, and reports of treatment response are rare. We describe a case of relapsed acute mixed type leukemia with bone marrow necrosis. The patient was a 10 year old female diagnosed with acute mixed type leukemia four years ago. She had been on second remission state for 1 year, presented with severe back pain, tenderness in lower extremities, low-grade fever and general weakness. Her level of serum lactic dehydrogenase on admission was increased. Bone marrow aspiration from both posterior iliac crest showed marrow necrosis. Subsequent examination showed the same feature. Hip MRI showed heterogenous low signal intensity in both iliac bone on T-1 weighted image and heterogenous high signal intensity on T-2 wieghted image. Remission induction therapy was started but she expired on 59th hospital day due to the complication of sepsis.
Key Words: Bone marrow necrosis, Leukemia


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