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Four Cases of Staphylococcal Scalded Skin Syndrome

Korean Journal of Pediatrics 2004;47(1):106-110.
Published online January 15, 2004.
Four Cases of Staphylococcal Scalded Skin Syndrome
Chul Han Park, Yoo Jin Jeong, Won Jung Choi, Sat Byul Park, Heung Sik Kim, Chin Moo Kang
Department of Pediatrics, School of Medicine, Keimyung University, Taegu, Korea
포도상 구균성 열상양 피부 증후군 4례
박철한, 정유진, 최원정, 박샛별, 김흥식, 강진무
계명대학교 의과대학 소아과학교실
Heung Sik Kim, Email: kimhs@dsmc.or.kr
Staphylococcal scalded skin syndrome is a systemic disease with a clinical spectrum ranging from subcorneal pustules, patterned exfoliation to extensive erosion and peeling of skin by the exfoliative toxin of group II Staphylococcus aureus. This disease occurs mainly in infancy and children below five years and it isn't easy to differentiate from other vesicular diseases clinically, but skin biopsy shows an epidermal split at the granular layer. The form and severity of staphylococcal scalded skin syndrome will vary according to defense system and toxic factors. Treatment is effective antibiotics, and the mortality rate increases to 5% in children. In our four cases, symptoms were erythema and fever, followed by formation of large bullae and denuded skin. On laboratory findings, leukocytosis was noted in three cases, and S. aureus was confirmed by culture of eye discharge in all cases. Our cases improved with antibiotic therapy. We experienced four cases of staphylococcal scalded skin syndrome which were presented with vesicle and exfoliative skin lesion and treated successfully.
Key Words: Staphylococcal scalded skin syndrome

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