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Sang Bum Lee  (Lee SB) 53 Articles
Original Article
Outcome of inflammatory response after normothermia during cardiopulmonary bypass surgery in infants with isolated ventricular septal defect
Dong Sub Kim, Sang In Lee, Sang Bum Lee, Myung Chul Hyun, Joon Yong Cho, Young Ok Lee
Clin Exp Pediatr. 2014;57(5):222-225.   Published online May 31, 2014
Purpose

A recent study analyzing several cytokines reported that long cardiopulmonary bypass (CPB) time and long aortic cross clamp (ACC) time were accompanied by enhanced postoperative inflammation, which contrasted with the modest influence of the degree of hypothermia. In this present study, we aimed to examine the effect of CPB temperature on the clinical outcome in infants undergoing repair of isolated...

Predictors of nonresponse to intravenous immunoglobulin therapy in Kawasaki disease
Hyo Min Park, Dong Won Lee, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2013;56(2):75-79.   Published online February 25, 2013
Purpose

It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond to intravenous immunoglobulin (IVIG) treatment. In this study, we aimed to identify useful predictors of therapeutic failure in children with KD.

Methods

We examined 309 children diagnosed with KD at the Kyungpook National University Hospital and the Inje University Busan Paik Hospital between January 2005...

Clinical features and surgical outcomes of complete transposition of the great arteries
Suk Jin Hong, Hee Joung Choi, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee, Joon Yong Cho
Clin Exp Pediatr. 2012;55(10):377-382.   Published online October 29, 2012
Purpose

This single-center study aimed to assess the clinical features and surgical approaches and outcomes of complete transposition of the great arteries (TGA).

Methods

TGA patients who had undergone surgical correction at the Kyungpook National University Hospital from January 2000 to December 2010, were retrospectively evaluated for patient characteristics, clinical manifestation, preoperative management, intraoperative findings, postoperative progress, and follow-up status.

Results

Twenty-eight patients (17 boys...

Wolff-Parkinson-White syndrome in young people, from childhood to young adulthood: relationships between age and clinical and electrophysiological findings
Hae Jung Jung, Hwang Young Ju, Myung Chul Hyun, Sang Bum Lee, Yeo Hyang Kim
Clin Exp Pediatr. 2011;54(12):507-511.   Published online December 31, 2011
Purpose

The aim of the present study was to evaluate the characteristics of electrophysiologic studies (EPS) and radiofrequency ablation (RFA) performed in subjects aged less than 30 years with Wolff-Parkinson-White (WPW) syndrome, particularly pediatric patients under 18 years of age, based on our experience.

Methods

Two hundred and one consecutive patients with WPW syndrome were recruited and divided to 3 groups according to...

NT-proBNP as a useful tool in diagnosing incomplete Kawasaki disease
Dong Won Lee, Yeo Hyang Kim, Myung Chul Hyun, Tae Chan Kwon, Sang Bum Lee
Clin Exp Pediatr. 2010;53(4):519-524.   Published online April 15, 2010
Purpose : To determine the efficacy of the N-terminal fragment of B-type natriuretic peptide (NT-proBNP) as a useful diagnostic method in children with incomplete Kawasaki disease (KD). Methods : Ninety-six patients who were diagnosed as having KD between January 2008 and June 2009 were enrolled in the study. American Heart Association recommendations for diagnosis were used, and patients were divided into...
Early postoperative arrhythmias after open heart surgery of pediatric congenital heart diseas
Hee Joung Choi, Yeo Hyang Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee, Kyu Tae Kim
Clin Exp Pediatr. 2010;53(4):532-537.   Published online April 15, 2010
Purpose : Early postoperative arrhythmias are a major cause of mortality and morbidity after open heart surgery in the pediatric population. We evaluated the incidence and risk factors of early postoperative arrhythmias after surgery of congenital heart disease. Methods : From January 2002 to December 2008, we retrospectively reviewed the medical records of the 561 patients who underwent cardiac surgery in Kyungpook National University...
Clinical features and results of recent total anomalous pulmonary venous connection : Experience in a university hospital (Clinical study of total anomalous pulmonary venous connection)
Mi Ae Chu, Byung Ho Choi, Hee Joung Choi, Yeo Hyang Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2009;52(2):194-198.   Published online February 15, 2009
Purpose : Active perioperative intervention and improvement on surgical technique has decreased the mortality rate of total anomalous pulmonary venous connection (TAPVC); however, when complicated with pulmonary venous obstruction, operative mortality is still high. The purpose of this study was to investigate the clinical course of TAPVC. Methods : Twenty-seven patients who were diagnosed with TAPVC (without other complex heart...
The changes in signal-averaged electrocardiogram after surgical correction of congenital heart disease
Yeo Hyang Kim, Hee Jung Choi, Gun Jik Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2009;52(12):1364-1369.   Published online December 15, 2009
Purpose : To analyze abnormal ventricular activation in childhood congenital heart disease induced by postoperative changes in ventricular volume and pressure and ventricular scar formation using signal-averaged electrocardiography (SAECG). Methods : Fifty-two patients who had undergone open heart surgery (OHS) were enrolled. Patients were divided into the following 3 groups: right ventricular volume overload (atrial septal defect, group1), left ventricular...
Epidemiologic study of Kawasaki disease in 6 months old and younger infants
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Joon Sung Lee, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2008;51(12):1320-1323.   Published online December 15, 2008
Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age. Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6...
Clinical features and results of recent neonatal cardiac surgery - A review of 82 cases in one hospital
Ki Won Oh, Jung Ok Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2007;50(7):665-671.   Published online July 15, 2007
Purpose : The purpose of this study was to investigate the clinical features and outcome in newborns undergoing cardiac surgery. Methods : Eighty two neonates underwent heart surgery for congenital heart defect at Kyungpook National University Hospital between March 2000 and February 2006. Patient characteristics (sex, age, diagnosis), pre-operative conditions, operation type, postoperative complications and mortality were reviewed retrospectively. Results : In...
Clinical features and surgical results of ruptured sinus of valsalva aneurysm
Tae Ho Lee, Dong Won Lee, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2006;49(3):287-291.   Published online March 15, 2006
Purpose : Aneurysms of sinus valsalva are rare anormalies thought to be primarily congenital in origin, progressing into death by acute heart failure in cases of rupture. Surgical correction is the only method of treatment. With these clinical implications, we reviewed the clinical characteristics and surgical results of patients with ruptured sinus of valsalva aneurysm. Methods : Between January 1991...
Quantitative Assessment of Myocardial Tissue Velocity in Normal Children with Doppler Tissue Imaging : Reference Values, Growth and Heart Rate Related Change
Se Young Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2005;48(8):846-856.   Published online August 15, 2005
Purpose : To measure the peak myocardial tissue velocities and patterns of longitudinal motion of atrioventricular(AV) annuli and assess body weight and heart rates-related changes in normal children. Methods : Using pulsed wave Tissue Doppler Imaging(TDI), we measurpeak systolic, early and late diastolic myocardial velocities in 72 normal children at six different sites in apical-4 chamber (A4C) view and at...
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2005;48(10):1139-1142.   Published online October 15, 2005
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of...
Usefulness of Intraoperative Transesophageal Echocardiography
Dong Won Lee, Byung Mok Kim, Sei Young Kim, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2004;47(12):1281-1286.   Published online December 15, 2004
Purpose : This study was undertaken to learn the usefulness, cost-effectiveness and safety of intraoperative transesophageal echocardiography(ITEE) during open heart surgery for congenital heart diseases. Methods : The usefulness and safety of ITEE were assessed in 254 patients who underwent open heart surgery for congenital heart diseases from January 1, 2001 to June 30, 2003, with retrospective chart reviews and a...
Abnormality of Regional Wall Motion of the Left Ventricle in Children with Ventricular Diastolic Overload
Yeo Hyang Kim, Sang Bum Lee
Clin Exp Pediatr. 2004;47(1):49-54.   Published online January 15, 2004
Purpose : To assess the regional wall motion of the left ventricle in patients with diastolic overloaded lesions of congenital heart diseases with centerline analysis and radial method. Methods : This study included 96 children with congenital heart diseases admitted to Kyungpook National University Hospital from January 1998 to December 2002 who received left ventriculograms. The evaluation of the regional wall...
Echocardiographic Parameters of Pulmonary Atresia with Intact Ventricular Septum(PA/IVS)
Young Seok Lee, Yeo Hyang Kim, Myung Chul Hyum, Sang Bum Lee
Clin Exp Pediatr. 2003;46(5):484-489.   Published online May 15, 2003
Purpose : To understand morphologic and hemodynamic variations in patients with pulmonary atresia with intact ventricular septum(PA/IVS), and to decide the best treatment modalities, we measured right ventricular volume, inflow, and outflow valvular annulus size in these patients and compared them with those of normal newborns. Methods : Eight patients with PA/IVS diagnosed by echocardiography from January to December 2001...
Hypoxia Induced Expression of Vascular Endothelial Growth Factor in Rat Pulmonary Artery Smooth Muscle Cells
Un Seok Nho, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2003;46(2):167-172.   Published online February 15, 2003
5% CO2-95% air atmosphere. The smooth muscle cells were confirmed by immunostaining with smooth muscle myosin and α-smooth muscle actin antibodies. The VEGF gene expression in the hypoxic group was compared with the one in control the group as well as the one in the starved group by RT-PCR and Northern blot hybridization. Results : There was no statistically significant difference...
Serial Changes of Cardiac Troponin I After Pediatric Open Heart Surgery
Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2002;45(2):208-213.   Published online February 15, 2002
Purpose : The major cause of cardiac dysfunction, after open heart surgery for congenital heart disease, is perioperative myocardial injury. Cardiac troponin I is found only within the myocardial cell, so it can be used as a biochemical marker of the myocardial injury. We performed this study to evaluate the worth of cardiac troponin I as a biochemical marker reflecting...
The Changes of Production of RANTES and Gro-α in Kawasaki Disease
Young Hwan Lee, Hyun Kyung Lee, Bo Hyeong Lee, Sun Yoon Jung, Hee Sun Kim, Sang Bum Lee
Clin Exp Pediatr. 2001;44(9):1002-1011.   Published online September 15, 2001
Purpose : Kawasaki disease is probably driven by abnormalities of the immune system after infectious insult. In this report, a clinical review with laboratory parameters and the changes of the plasma levels of chemokines(RANTES and Gro-α) was undertaken according to the clinical stage of Kawasaki disease. Methods : This investigation included 74 samples from 21 patients(10 boys, 11 girls; mean age, 27.8 months) with Kawasaki...
Morphometric Analysis of the Infundibulum in Tetralogy of Fallot
Su Hee Kwak, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2000;43(9):1187-1191.   Published online September 15, 2000
Purpose : The morphogenic mechanism of tetralogy of Fallot is known to be an antero-superior deviation and hypertrophy of the subpulmonary infundibulum. We performed this study to measure the subpulmonary infundibulum in patients with tetralogy of Fallot and compare those with normal control. Methods : Echocardiographic data and medical reports of 12 patients, with classical tetralogy of Fallot who were diagnosed...
Transcatheter Closure of the Patent Ductus Arteriosus
Young A Lee, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 2000;43(9):1200-1206.   Published online September 15, 2000
Purpose : Transcatheter closure of the patent ductus arteriosus(PDA) is a well-established, effective therapeutic modality, and many kinds of devices have been used to perform this closure. The aim of this study is to compare the effects of different kinds of devices. Methods : We reviewed retrospectively the charts of 43 patients who were admitted to Kyungpook University Hospital between June...
Short-term Result of Radiofrequency Catheter Ablation in Pediatric Patients with Paroxysmal Tachycardia
Hee Suk Jang, Hee Jung Cho, Myung Chul Hyun, Sang Bum Lee, Young Keun Cho, Chang Ho Han
Clin Exp Pediatr. 2000;43(2):203-209.   Published online February 15, 2000
Purpose : To find out the efficacy, safety and early complication of radiofrequency catheter ablation(RFCA) in pediatric patients with paroxysmal tachycardia, we compared short-term results of RFCA in pediatric patients to adult patients. Methods : We studied 25 patients(11 pediatric patients, 14 adult patients), who underwent RFCA due to paroxysmal supraventricular tachycardia(PSVT) or idiopathic ventricular tachycardia(VT) from November 1997 to August...
Depolarization, Repolarization Inhomogeneity and Late Potential after Surgical Repair of Tetralogy of Fallot
Soo Young Kim, Myung Chul Hyun, Sang Bum Lee, Seung Tae Kim, Jong Soo Lee
Clin Exp Pediatr. 1999;42(8):1071-1077.   Published online August 15, 1999
Purpose : After repair of tetralogy of Fallot(TOF), ventricular arrhythmia and sudden death remain as serious late complications which are due to right ventricular systolic and diastolic overloading, exposure to hypoxia and surgical scar. Among the various methods for predicting the risk of such complications, we evaluated signal average ECG(SAECG), QRS duration, QT and JT dispersion, cardiothoracic(CT) ratio, age at...
Assessment of Regional Wall Motion of the Left Ventricle in Children with Congenital Heart Disease
Chang Hee Han, Jun Ho Huh, Un Seok Nho, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1999;42(6):807-816.   Published online June 15, 1999
Purpose : To assess wall motion of the left ventricle in the various forms of congenital heart disease and to select appropriate methods by which to gauge left ventricular wall motion. Methods : We evaluated left ventricular function, including volume, global ejection fraction, and regional wall motion(Centerline method, Local Ejection Fraction, Curved Perimeter method and Radial method). The evaluation was done...
Clinical Observations of Coarctation of the Aorta
Hui Jung Cho, Chang Ho Ha, Dong Seok Lee, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1999;42(4):519-525.   Published online April 15, 1999
Purpose : Due to controveries surrounding in the incidence of coarctation of aorta which reports previously stated rare among Orientals, we evaluated clinical characteristics, natural courses of coarctation of aorta and effects of different surgical modalities. Methods : Medical records of 51 patients with coarctation of aorta, diagnosed by 2-dimensional echocardiography in Kyungpook University Hospital Pediatric Cardiac Laboratory from June 1985...
Fixed Subaortic Stenosis in Children
Eun Jin Choi, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1997;40(4):505-511.   Published online April 15, 1997
Purpose : This study attempted to describe the Doppler and two-dimensional echocardiographic features of fixed subaortic stenosis, the de novo occurrence and progression of this lesion and to review its etiology, treatment and course. Methods : We studied 17 patients of fixed subaortic stenosis who, between Jan. 1993 and Jan. 1996, ware diagnosed by echocardiographic examination at Kyungpook National University Hospital....
Clinical Lecture
Clinical Presentation of Heart Diseasein Infants and Children
Sang Bum Lee
Clin Exp Pediatr. 1997;40(3):301-306.   Published online March 15, 1997
Original Article
Clinical Course of Atrioventricular Septal Defect(AVSD) in Down and non Down syndrome
Un Seok Nho, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1996;39(9):1288-1294.   Published online September 15, 1996
Purpose : It is well known that 1/3 - 1/2 of Atrioventricular septal defect(AVSD) patients also have Down syndrome which may influence the clinical course of AVSD. To know the anatomic type of AVSD and the effect of Down syndrome on the clinical course of AVSD, we studied 37 cases( Down group: 14 cases, non Down group: 23 cases) who were diagnosed and...
Serial Changes of Doppler Echocardiographic Transvalvular Velocity during the Neonatal Period in Full Term Neonates
Woo Taek Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1996;39(7):977-986.   Published online July 15, 1996
Purpose : We performed this study to compare serial measurements which relate to both ventricular functions in full term neonates for the first three weeks after birth. Methods : Echocardiographic and pulsed Doppler studies were performed for 20 newborns during the first 36 hours of life, and subsequent serial studies in the second (n=13) and third(n=12) weeks of life. Evaluation included measurements of both...
Clinical Significance of Simple Ventricular Septal Defect
Chang Ro Park, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1996;39(5):652-657.   Published online May 15, 1996
Purpose : To investigate the clinical significance and frequency of simple VSD by location of the defect and hemodynamic severity. Methods : We studied 482 cases who were diagnosed as simple VSD at department of Pediatrics, Kyung Pook University Hospital between December 1983 and July 1993. All cases were diagnosed by 2 dimensional echocardiography and cardiac catheterization was done in 256 cases. Results :...
Myocardial Functions Estimated by Pulsed Doppler Echocardiography in Patientswith Chronic Renal Failure
Hyun June Huh, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1996;39(12):1712-1728.   Published online December 15, 1996
Purpose : The objectives of this study were to estimate myocardial functions in patients with chronic renal failure by pulsed Doppler echocardiography, and investigate correlation between Doppler and disease parameters. Methods : We studied 13 patients with chronic renal failure whose creatinine clearance rate less than 25ml/min. Using pulsed Doppler echocardiography with curve following method, we measured peak velocity, mean velocity, velocity-time integral and peak...
Clinical Course of the Ostium Secundum Atrial Septal Defect(ASD) and Its Rate of Spontaneous Closure
Dae Yong Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1996;39(11):1538-1543.   Published online November 15, 1996
Purpose : To know the natural course of the ostium secundum ASD including its rate of spontaneous closure. Methods : We studied 259 cases who were diagnosed as ostium secundum ASD by 2D-echocardiography at Department of Pediatrics, Kyungpook National University Hospital between Jan. 1985 and Dec. 1994. According to the age at diagnosis, we divided them into two groups, group I (those diagnosed before 1...
Serial M-mode Echocardiographic Assessment of Left Ventricular Function in Kawasaki Disease
Byung Ho Choi, Jin Kyung Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1994;37(6):759-766.   Published online June 15, 1994
To investigate the effect of kawasaki disease on left ventricular function, we studied 92 patients with Kawasaki disease at initial visit, after 3 months (78 patients) and after 1 year (9 patients). Using serial M-mode echocardiogram, we obtained LVD(d) (left ventricular internal dimension at end diastole), LVD(s)(left ventricular internal dimension at end systole), FS(fractional shortening), ET(ejection time), VmCF(mean velocity of circumferential...
Plasma Atrial Natriuretic Peptide Concentrations of the Pulmonary artery, Aorta and Veins in Children with Cardiac Disease
Kang Il Lee, Nam Geun Heo, Myung Chul Hyun, Sang Bum Lee, Eun Kyoung Yang, Won Jung Lee
Clin Exp Pediatr. 1994;37(4):481-493.   Published online April 15, 1994
To study the site of release and factors affecting the releases of the atrial natriuretic peptide (ANP) in the pediatric patients, we measured the plasma ANP concentrations in 23 normal healthy children, 19 patients with congestive heart failure and 16 patients with cardiac disease undergoing diagnostic cardiac catheterization. The following results were obtained. 1) The plasma ANP concentrations of the vein (226.3¡¾74.9...
Serial Doppler Echocardiographic Evaluation of Anthracycline Induced Left Ventricular Dysfunction in Children
Nam Geun Heo, Myung Chul Hyun, Kun Soo Lee, Sang Bum Lee
Clin Exp Pediatr. 1993;36(2):214-222.   Published online February 15, 1993
Anthracycline drugs are chemoterapeutic agents highly effective against a wide range of neoplasms. However, its administration may be complicated by cardiotoxic reactions. There is a continuum of increasing risk with increasing total dose of drug rather than an absolute cutoff point for total dose drug of that should not be exceeded under any circumstances. At the present time it appears that a...
A Comparison of Reagent Test Strip-photometer and Laboratory Plasma Glucose Values in Newborns
Jin Kyung Kim, Myung Chul Hyun, Sang Bum Lee, Heng Mi Kim
Clin Exp Pediatr. 1992;35(8):1501-1058.   Published online August 15, 1992
Although reagent test strip-photometer method is frequently used to estimate plasma glucose values in nurseries, the accuracy in newborns have not been evaluated previously. In this study values of 44 samples of laboratory glucose were compared with values simultaneously obtained by reagent test strip-photometer. Laboratory values were determined by glucose oxidase method using veous plasma. Reagent test strip-photometer values were determined...
Percutaneous transluminal balloon valvuloplasty for congenital pulmonary valvular stenosis.
Sung Min Choi, Sang Bum Lee, Doo Hong Ahn, Yong Joo Kim
Clin Exp Pediatr. 1991;34(3):311-316.   Published online March 31, 1991
Congenital pulmonary valvular stenosis was relieved by percutaneous balloon valvuloplasty during cardiac catheterization on 8 children aged 14 months to 8 years. Before dilatation, the transpulmonary systolic pressure gradients ranged from 33 mmHg to 79 mmHg (Mean:52.00 ± 18.16 mmHg). There were significant reduction in the transpulmonic systolic pressure gradients immediate after balloon dilatation (Mean:17.38±11.16mmHg). In follow up 4 patients, this decreased pressure gradients have...
Assessment of Cardiac Output by Doppler Ultrasound Technique Alone.
Young Ho Ahn, Sung Min Choi, Nam Geun Heo, Sang Bum Lee
Clin Exp Pediatr. 1990;33(8):1074-1080.   Published online August 31, 1990
The normal range of ascending aortic blood velocity was determined in 23 healthy children including 8 newborn infants and compared with 12 anemic children, using a pulsed Doppler ultrasound technique from suprasternal long axis view. Integration of the area under the velocity-time curve for each heart beat gave stroke distance, which, when multiplied by heart rate, gave minute distance. Stroke distance and minute distance are...
Statistical Analysis of Pediatric Diseases in Korea(1987).
Kyong Su Lee, Ki Sup Chung, Ki Yang Ryoo, Woo Gill Lee, Sang Bum Lee, Se Jin Kang, In Kyung Sung
Clin Exp Pediatr. 1989;32(7):885-896.   Published online July 31, 1989
The Korean pediatric association is conducting the analysis of disease patterns of children by the body organ system. For the purpose of assessing the disease patterns in patients of the pediatric age in Korea, we performed a statistical analysis of diseases of patients admitted to the department of pediatrics in 36 hospitals having pediatric residency programs in 1987. The results obtained were as follows, 1) Total...
The Collaborative Clinical Analysis of 985 Cases of Rheumatic Fever and Rheumatic Carditis in Children for 10 Years(1978~1987) in Korea.
Sung Ho Cha, Sang Young Jeong, Du Bong Lee, Kyong Su Lee, Sang Bum Lee, Tae Chan Kwon, Young Chang Tockgo, Chang Sung Sohn, Keun Chan Sohn, Young Jin Hong, Chan Young Kim, Chang Yee Hong, Yong Soo Yun, Jung Yun Choi, Chang Hwi Kim, Chul Ho Kim, Tae Ju Hwang, Jae Suk Ma, Chan Uhul Joo, Kyoo Hwan Rhee, Hahng Lee
Clin Exp Pediatr. 1989;32(12):1621-1631.   Published online December 31, 1989
Acute rheumatic fever and rheumatic carditis were still important disease of the acquired heart disease in children and adults, in spite of improving socioeconomic status in Korea. Recently, many outbreaks of acute rheumatic fever have been reported in the papers from developed countries. We should be aware of such outbreaks of acute rheumatic fever and should pay attention to their treatment of the patients...
Noninvasive Estimation of Pulmonary Artery Pressure with Doppler Echocardiogrphy.
Ji Yean Lee, Soon Hak Kwon, Sang Bum Lee, Doo Hong Ahn
Clin Exp Pediatr. 1989;32(1):20-26.   Published online January 31, 1989
This study determined the accuracy of Doppler echocardiography for predicting the pulmonary artery pressure from right ventricular systolic time intervals in 25 pediatric patients with various congenital cardiovascular diseases undergoing cardiac catheterization. Either estimated pulmonary artery systolic pressure (PASP) using Burstin nomogram and pulmo- nary artery diastolic pressure (PADP) using Riggs equation (PADP= 151· RPEP / RVET ·20.7) correlated well with the pressures at...
Chronic Renal Failure in Children.
Kyung Ok Lee, Young Ho Ahn, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1988;31(6):738-746.   Published online June 30, 1988
Present study was undertaken to see the various clinicopathologic findings and outcome on 18 children with chronic renal failure, who had been admitted to the Pediatric department of Kyungpook National University Hospital from 1978 to 1986. And the following results were obtained. Male to female ratio was 5 to 4 and in 15 out of 18 cases, renal failure developed after 5 years of...
Statistical Analysis of Pediatric Diseases in Korea.
Kyong Su Lee, Ki Sup Chung, Ki Yang Ryoo, Woo gill Lee, Sang Bum Lee, Se Jin Kang
Clin Exp Pediatr. 1988;31(6):678-690.   Published online June 30, 1988
Statistical analysis of pediatric diseases in patients admitted to the department of pediatrics in 34 hospitals having pediatric residency program for 2 years from Jan. 1985 to Dec. 1986 was underwent for the purpose of assessing the disease pattern in the pediatric aged people in Korea. The results obtained were as follows 1) Total number of inpatients was 112,309, of which 69,266 were male and...
Ventnricular Septal Defect with Septal Aneurysm.
Hae Woon Chang, Chul Woo Ku, Sang Bum Lee, Doo Hong Ahn
Clin Exp Pediatr. 1987;30(7):742-748.   Published online July 31, 1987
Clinical and hemodynamic data were evaluated and analyzed in 31 cases of ventricular septal defect with septal aneurysm which were confirmed by 2-D echocardiography and left ventriculography at Kyungpook National University Hospital during the period of one year from June, 1985 to June, 1986 Septal aneurysms were found in 31 (41.9%) of 74 cases of total VSD (30 cases in membranous VSD and one...
Noninvasive Assessment of Pressure Gradient by Quantitative Two-Dimensional Echocardiographic Doppler Studies in Pediatric Cardiovascular Diseases.
Wang Bok Lee, Hye Li Chung, Dong Jin Lee, Sang Bum Lee
Clin Exp Pediatr. 1987;30(5):518-526.   Published online May 31, 1987
In this study we assessed the predictive accuracy of continuous wave Doppler echocardiography for noninvasive measurement of pressure gradients in various pediatric cardiovascular diseases. We studied 32 children, ages 50 days to 12 years, prior to cardiac catheterization or after palliative operation and compared Doppler-estimated gradients and gradients obtained at catheterization or operation. The ultrasound beam was aligned as much as possible to...
Diagnostric Significance of Subxiphoid Two-Dimensional Echocardiography in Congenital Heart Desease of Chlidred.
Kwang Do Lee, Cheol Woo Ko, Hong Bae Kim, Sang Bum Lee, Doo Hong Ahn
Clin Exp Pediatr. 1986;29(3):296-304.   Published online March 31, 1986
Subxiphoid, two-dimensional echocardiographic examinations were performed and interpreted before diagnostic cardiac catheterization on 138 patients with suspected congenital heart disease who were from 2 months to 15 years old. Cardiac catheterization and cineangiographic examination were performed in all patients and surgery in 99 patients and comparisions were made with each other. Eighteen of nineteen patients with an atrial...
The Effect of Intravenous Gammaglobulin for Acute Idiopathic Thrombocytopenic Purpura in Children.
Seung In Baek, Geum Joo Kim, Kuhn Soo Lee, Sang Bum Lee, Doo Hong Ahn
Clin Exp Pediatr. 1985;28(5):483-491.   Published online May 31, 1985
A clinical study was conducted to determined the effectiveness of intravenous gammaglobulin on childhood acute ITP. Study group consisted of 8 children who were treated with IV Globulin(0.4 gm/kg/d, 5 days) only or combined with steroid, and control group of 19 children who were treated with steroid only. Study period was from January 1980 to June 1984, and following results...
A Clinical Observation on Isolated Ventricular Septal Defect In Children.
Chang Ho Lee, Kwang Do Lee, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1984;27(7):702-710.   Published online July 31, 1984
A clinical study was done an 39 cases of isolated VSD who had been admitted to the Pediatric Department of Kyungpook National University Hospital, and and confirmed by cardiac catheterization during the period from January 1975 to May 1983. The results were as follows; Out of 77 cases of congenital heart disease underwent cardiac catheterization, 39 cases were isolated VSD,...
A Clinical Study on Children with Acute Glomerulonephritis.
Jeong Gwon Lee, Dong Jin Lee, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1983;26(1):48-56.   Published online January 31, 1983
A clinical observation has been made on 104 children with acute glomerulonephritis who were admitted to pediatric Dept, of Kyung-Pook University hospital during 4 1/2 year period, from August 1977 to December 1981. Male to female ratio was 1.5 : 1 and peak incidence was noticed on cold months from November to January when URI was most prevalent. Cases were evenly distributed...
Late Hemorrhagic Disease of Infancy due to Vitamin K Dependent Factor Deficiency.
Kang Il Lee, Yong Soon Kim, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1982;25(1):52-57.   Published online January 31, 1982
A clinical study was done on 9 children with 10 episodes, who were admitted to our pediatric ward under the diagnosis of late hemorrhagic disease of infancy due to vitamin K dependent factor deficiency. Study period was past 2 years, from September 1979 to May 1981. The following results were obtained. This disorder occurred most frequently during early infancy, with...
Case Report
A Case report of Bird-headed Dwarfism(Seckel's Syndrome).
Yong Soon Kim, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1981;24(11):1116-1120.   Published online November 15, 1981
Recently we have experienced a male baby, who bear a striking resemblance to bird-headed dwarfism. Review of literatures has been done and we believe this is the first ca多e reported in Korea.
Original Article
A Clinical Study on Sepsis in Children: esp. about buffy coat smear.
Nam Keun Cho, Haeng Mi Kim, Sang Bum Lee, Ja Hoon Koo, Sung Yong Seol
Clin Exp Pediatr. 1980;23(5):376-383.   Published online May 15, 1980
A clinical and laboratory study was conducted on 58 children who had been admitted to out pediatric department from February to September 1979, under the clinical diagnosis of septicemia. Following results were obtained: 1. Boys were affected more frequently than girls(1.3:1), and highest incidence was noticed in newborn period, comprising 50% of the total cases. 2. The common clinical manifestations,...
Relationship Between Neonatal Hypocalcemia and Q-oTc Interval.
Won Cho Chung, Kwang Tae Chung, Sang Bum Lee, Ja Hoon Koo, Doo Hong Ahn
Clin Exp Pediatr. 1980;23(5):358-365.   Published online May 15, 1980
A study has been conducted to see the relationship between Q-oTc interval and neonatal hypocalcemia study group consists of 75 Newborns(full-Term 57, premature 18), whose conditions were Known to be susceptable to the development of hypocalcemia and all of them were admitted to the newborn service of Kyungpook National University Hospital during 6 months period from February to August, 1978....


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