Epidemiologic study of Kawasaki disease in 6 months old and younger infants |
Yong Won Park1, Ji Whan Han2, In Sook Park3, Chang Hwi Kim4, Sung Ho Cha5, Jae Sook Ma6, Joon Sung Lee2, Tae Chan Kwon7, Sang Bum Lee8, Chul Ho Kim1, Heung Jae Lee9, Yong Soo Yun10 |
1Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea 2Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea 3Department of Pediatrics, College of Medicine, University of Ulsan, Seoul, Korea 4Department of Pediatrics, College of Medicine, Soonchunhyang University, Korea 5Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea 6Department of Pediatrics, College of Medicin, Chonnam National University, Kwangju, Korea 7Department of Pediatrics, College of Medicine, Keimyung University, Taegu, Korea 8Department of Pediatrics, College of Medicine, Kyungpook National University, Taegu, Korea 9Department of Pediatrics, College of Medicine, Sungkyunkwan University, Seoul, Korea 10Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea |
6개월 이하 영아에서의 가와사끼병의 역학적 연구 |
박용원1, 한지환2, 박인숙3, 김창휘4, 차성호5, 마재숙6, 이준성2, 권태찬7, 이상범8, 김철호1, 이흥재9, 윤용수10 |
1인제대학교 의과대학 소아과학교실 2가톨릭대학교 의과대학 소아과학교실 3울산대학교 의과대학 소아과학교실 4순천향대학교 의과대학 소아과학교실 5경희대학교 의과대학 소아과학교실 6전남대학교 의과대학 소아과학교실 7계명대학교 의과대학 소아과학교실 8경북대학교 의과대학 소아과학교실 9성균관대학교 의과대학 소아과학교실 10서울대학교 의과대학 소아과학교실 |
Correspondence:
Yong Won Park, Email: yongpw@hanmail.net |
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Abstract |
Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age.
Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6 months of age were analyzed and compared with those of KD patients >6 months of age.
Results : A total of 1,739 patients ≤6 months of age, including 1,088 males and 651 females, represented 7.7% of total KD patients. These subjects included 22 patients aged <1 month, 171 patients aged 1-2 months, 304 patients aged 2-3 months, 407 patients aged 3-4 months, 372 patients aged 4-5 months, and 463 patients aged 5-6 months. Their mean age of onset was 4.3 months, and the male-to-female ratio was 1.67:1. Incidences of coronary arterial (CA) abnormalities (21.0% versus 18.7%) and CA aneurysms (4.7% versus 3.1%) detected by echocardiography showed differences between patients with KD younger and older than 6 months, respectively.
Conclusion : Comparison of data from KD patients >6 months old with data from 1,739 KD patients ≤6 months old showed significantly higher incidences of CA abnormalities and CA aneurysms in the younger patients. |
Key Words:
Mucocutaneous lymph node syndrome, Coronary aneurysm, Epidemiology, Infant |
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