- Original Article
- Correlation between the morning hypertension on ambulatory blood pressure monitoring and the left ventricular mass in children
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Hyun Jung Kim, Kyung Hee Kim, Hong Ryang Kil
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Clin Exp Pediatr. 2014;57(9):403-409. Published online September 30, 2014
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Purpose Although high morning blood pressure (BP) is known to be associated with the onset of cardiovascular events in adults, data on its effects in children with hypertension are limited. Our retrospective study aimed to define the clinical characteristics of children with morning hypertension (MH) and to determine its associated factors. MethodsWe reviewed 31 consecutive patients with hypertension, confirmed by the ambulatory... |
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- Cardiovascular risk factors of early atherosclerosis in school-aged children after Kawasaki disease
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Hyun Jeong Cho, Soo In Yang, Kyung Hee Kim, Jee Na Kim, Hong Ryang Kil
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Clin Exp Pediatr. 2014;57(5):217-221. Published online May 31, 2014
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Purpose The aim of this study was to determine whether school-aged children with Kawasaki disease (KD) have an increased risk for early atherosclerosis. MethodsThe study included 98 children. The children were divided into the following groups: group A (n=19), KD with coronary arterial lesions that persisted or regressed; group B (n=49), KD without coronary arterial lesions; and group C (n=30), healthy children.... |
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- Antithrombin III in the Diagnosis and Treatment of Disseminated Intravascular Coagulation in Premature Infants
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Su Jin Cho, Hye Ryung Choi, Young Mi Hong, Kyung Hee Kim, Keun Lee, Eun Ae Park
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Clin Exp Pediatr. 2004;47(7):740-745. Published online July 15, 2004
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Purpose : We evaluated the diagnostic implications and therapeutic efficacy of antithrombin III(AT III) in the disseminated intravascular coagulation(DIC) of premature infants.
Methods : Ninety-two premature infants diagnosed with DIC and treated with AT III from March, 2000 to May, 2003 were retrospectively reviewed. Clinical manifestations, complete blood counts, coagulation tests, and AT III levels were compared between the two groups... |
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- The Separate and Combined Effects of Insulin, Dexamethasone and
Growth Hormone on the OB Gene Expression and Leptin Secretion
from Cultured Human Visceral Adipose Tissue
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Il Tae Hwang, Kyung Hee Kim, Jin Soon Hwang, Choong Ho Shin, Sei Won Yang
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Clin Exp Pediatr. 2003;46(8):795-802. Published online August 15, 2003
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Purpose : We investigated the hormonal control of OB gene expression and leptin secretion in cultured human visceral adipose tissue.
Methods : Visceral adipose tissues were cultured for up to 48 hrs in modified Eagle's medium with varying concentration of hormones : Control(no hormone), bovine insulin(100 nM), Dexamethasone(DEX, 100 nM), growth hormone(GH, 40 ng/mL), insulin＋DEX(100 nM each), insulin＋DEX＋GH(100 nM insulin... |
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- The Changes of Apoptosis and Viability in Stem Cells after Thawing with Lapse of the Time
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Seun Joo Park, Sang Young Bae, Kyung Ha Ryu, Il Tae Whang, Kyung Hyo Kim, Young Mi Hong, Kyung Hee Kim, Keun Lee, Joo Young Seoh
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Clin Exp Pediatr. 2000;43(12):1576-1582. Published online December 15, 2000
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Purpose : Thawed stem cells should be infused as early as possible because delay of infusion leads to decrease of cell viability and formation of DNA clumping. The procedure of 10% Dimethyl sulfoxide(DMSO) removal and a long distance from the thawing location to the patient are the main causes of delay of infusion that results in the loss of cell... |
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- Case Report
- A Case of Multicystic Encephalomalacia in a Liveborn Twin with a Stillborn Co-twin
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Mi Ya Park, Kyung Hee Kim, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim
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Clin Exp Pediatr. 1997;40(3):429-433. Published online March 15, 1997
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Multicystic encephalomalacia is the condition defined anatomically by the presence of
multiple cavities in the great part of both cerebral hemispheres. The most common
cause of the condition was regarded as the circulatory disturbance during the perinatal period. Also,neonatal asphyxia was the most important cause of the circulatory disturbance.
But we experienced a case of multicystic encephalomalacia in a liveborn twin with a
stillborn... |
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- Original Article
- Varicella Zoster Virus Spicific IgG Antibody Titer in Vaccinated and Infected Children
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Young Eun Lee, Eun Ae Park, Kyung hee Kim
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Clin Exp Pediatr. 1996;39(7):934-942. Published online July 15, 1996
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Purpose : Varicella is mild self limited disease with vesicular skin eruption but highly
contagious and accompanied many complications. Especially, varicella is fatal in leukemic children
and immunocompromised children. The live varicella zoster virus was first developed by
Takahashi et al. in the 1974. This vaccine has now been licensed for general use in Europe and
the United States as well as in Korea..
The... |
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- Case Report
- A Case of Cystic Pancreatoblastoma Associated with Congenital Hemihypertrophy
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Hyun Joo Lee, Kyuong Ha Yoo, Young Mi Hong, Kyung hee Kim, Kum Ja Choi, Joung Hyun Yoo, Sung Sook Kim
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Clin Exp Pediatr. 1996;39(6):861-865. Published online June 15, 1996
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We experenced a case of cystic pancreatoblastoma associated with congenital hemihypertrophy in a 4months old male. The mass was located on the anterior side of pancreatic head without any connection to the pancreas. After exision of cystic pancreatoblastoma, chemotherapy(FAM regimen) was performed 15 times due to capsular tumor invasion. Until this time there was no drug side effect and metastasis.... |
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- Original Article
- Auditory Brainstem Responses in Premature and Fullterm Infants
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Hyun Mi Kim, Tae Sung Ko, Ki Soo Kim, Moo Song Lee, Kyung Hee Kim
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Clin Exp Pediatr. 1995;38(8):1036-1045. Published online August 15, 1995
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Purpose : We tried to know normal range of auditory brainstem responses in premature and fullterm infants who have no rksk factor during perinatal period and to determine that the abnormal ABR in premature and fullterm infants may predict developmental delay.
Methods : ABR evaluations were performed on 283 premature and fullterm infants from NICU of the Asan Medical Center during... |
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- Case Report
- A Case of Glycogen Storage Disease Type Ⅰb
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Ji Young Rhou, Eun Yae Park, Kyung Hee Kim, Su Yeun Jo, Hye Su Koo
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Clin Exp Pediatr. 1995;38(4):545-551. Published online April 15, 1995
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Glycogen storage disease(GSD) type Ⅰis due to defect of glycose-6-phosphatase at the membrane of the endoplasmic reticulum in liver. Clinical presentations of GSD 1 are massive hepatomegaly without splenomegaly, failure to thrive, bleeding tendency, hypoglycemia, fasting ketosis and hyperlipidemia. The appearance of patient is short and fat with particularly fat cheeks. Mental development is usually normal. It was diagnosed by... |
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- Original Article
- Varicella-zoster Antibody Titer in Neonates according to Gestational Age
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Ji Young Rhou, Eun Yae Park, Kyung Hee Kim
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Clin Exp Pediatr. 1995;38(3):311-318. Published online March 15, 1995
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Purpose : Acquisition of varicella by the neonate as a result of congenital varicella-zoster infection or exposure during delivery is well known. And it generaly believed that infants under 6 months of age may acquire varicella more frequently than other viral infections such as measles. However, little if known about immune mechanism of varicella-zoster infection. Transfer maternal antibodies to this... |
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- Case Report
- A Case of Congenital T Cell Lymphoblastic Lymphoma
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Eun Sun Yoo, Young Mi Hong, Kyung Hee Kim, Hae Soo Gyu, Eun Chul Chung
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Clin Exp Pediatr. 1994;37(9):1296-1304. Published online September 15, 1994
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T cell lymphoblastic lymphoma is characterized by immature lymphoid cells that are indistinguishable from the lymphoblasts and prolymphocytes of acute lymphoblastic leukemia. Several characteristic clinical features of lymphoblastic lymphoma, with include a high male-to-female ratio, a relatively high incidence in older children and young adults, the frequent presence of mediastinal involvement at the time of diagnosis. Also, this disease is... |
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- Original Article
- Airway Resistance after Exercise Loading Test in Asthmatic Children
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Ji Eun Lee, Young Mi Hong, Kyung Hee Kim
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Clin Exp Pediatr. 1994;37(10):1333-1339. Published online October 15, 1994
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Exercise induced asthma(EIA) is defined as acute, reversible, usually self-immiting airway obstruction which develop after strenous exercise in patients with asthma. EIA is a bigger problem in children than adults due to more active and smaller airways which obstruct more easily when bronchospasm develops. The exercise elicited amny change in pulmonary function of asthmatic children. These change could be measured... |
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- Anemia due to Prolonged Breast Feeding without Weaning Diet or Supplement Food
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Kyung Hee Kim, Kun Rae Lee, Hyun Lee, Yoon Suck Suh, Baek Lin Eun
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Clin Exp Pediatr. 1993;36(4):528-536. Published online April 15, 1993
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The paramount importance of breast feeding for the health of the infants has been recognized by nutritionists and physicians. Although many advantages of the breast feeding, exclusive breast feeding without weaning diet or supplement food during prolonged period in infants may produce iron deficiency anemia.
This study was conducted to find out the hematologic state in exclusively prolonged breast-fed infants among... |
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- A Study on Serum Immunoglobulins and Complements in Newborn Infants by Gestational Weeks
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Ji Eun Lee, Kyung Hyo Kim, Kyung Hee Kim
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Clin Exp Pediatr. 1993;36(11):1555-1561. Published online November 15, 1993
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The author investigated serum immunoglobulin (IgG, IgA, and IgM) and complements (C3) of cord blood in 74 cases of normal fulterm infants and 50 cases of premature infants. Serum immunolglobulin and complement levels were measured by the single radial immunodiffusion method.
The following results were obtained ;
1) The mean serum IgG levels of cord blood in 74 cases of the normal... |
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- Clinical Observation on Reye syndrome According to the Onset of Age in Children
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Kyung Hee Kim, Baik Hee Lee, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
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Clin Exp Pediatr. 1992;35(6):788-794. Published online June 15, 1992
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A clinical observation according to the age of onset was made on 40 children with Reye syndrome who had been admitted to pediatric department of National Medical Center during 11 year period from January 1979 to December 1989.
1) Annual distribution showed the largest number in 1982. There was no significant difference in seasonal distribution.
2) Cases of infant comprised 22 (55.0%)... |
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- Case Report
- A Case of Agenesis of the Right Lung with H-type Tracheoesophageal Fistula
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Yong Seok Choi, Kyung Hee Kim, Young Chul Ahn, Baik Lin Eun, Kwang Je Beck
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Clin Exp Pediatr. 1992;35(6):816-821. Published online June 15, 1992
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Agenesis of the lung is a developmental defect with complete absence or profound hypoplasia of one or both lung : absence of one lung is more common. Absence of both lung is very rare and is incompatible with life. Unilateral or bilateral agenesis of the lung often associated with the skeletal, cardiovascular, gastrointestinal and genitourinary anomalies. H-type tracheoesophageal fistula in... |
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- Original Article
- Follow up Study of Urinary Tract Infection Associated with Vesicoureteral Reflux
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Kyung Hee Kim, Young Jin Hong, Soon Wha Kim, Don Hee Ahn
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Clin Exp Pediatr. 1992;35(12):1713-1721. Published online December 15, 1992
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The authors studied 25 cases with urinary tract infection associated with vesicoureteral reflux who were admitted to department of pediatrics, National Medical Center.
The patients were managed medically or surgically and followed up.
The results were summarized as follows;
1) There were no difference in age and sex distributions of the 25 cases with vesicoureteral reflux.
2) The degree of reflux classified by International... |
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- Prevalence of hepatitis B surface antigen in pediatric in patients.
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Kyung Hee Kim, Myung Ik Lee, Young Jin Hong, Keun Chan Sohn
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Clin Exp Pediatr. 1991;34(3):355-362. Published online March 31, 1991
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Thirty three from 689 children (4.79%) who were screened among hospitalized patients from July,
1986 to June, 1988, were positive for hepatitis B surface antigen in their serum sample tested by
radioimmunoassay. The positive rate of hepatitis B surface antigen was 3.04% when the hepatitis
patients were excluded. The incidence of hepatitis B surface antigen was higher (5.18%) in male than
in famale (4.17%)... |
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- A measurement of measles antibody titer in pediatric age group.
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Min Hyea Kim, Jee Eun Lee, Jung Weon Seo, Young Mee Hong, Kyung Hee Kim
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Clin Exp Pediatr. 1991;34(11):1519-1525. Published online November 30, 1991
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We measured the degree of immunity of 155 childrens with the age from birth to 12 years to measles
antibody titer by enzyme-linked immunosorbent assay (ELIZA) for determine the proper age the
Measles vaccination.
The results were as follows;
1) By age group, 64% of the children was positive for Measles IgG antibody with the age between
1 and 2 months and 17% of the children with... |
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- The Apgar Score and Umbilical Arterial pH in the Newborn.
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Hoo Jae Hann, Eun Ae Park, Kyung Hee Kim
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Clin Exp Pediatr. 1990;33(8):1048-1056. Published online August 31, 1990
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In this prospective study, the relation between the Apgar scores and umbilical arterial pH at birth
was assessed. 314 newborns of gestational age 24 to 42 weeks were included in this study； (95 were
preterm and 219 were full-term) The l and 5-minute Apgar scores were directly related to gestational
age. In preterm babies, the Apgar scores tend to be low in spite... |
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- Pulmonary Air Leaks in the Newborn.
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Soon Wha Kim, Kyung Hee Kim, Young Jin Hong, Don Hee Ahn
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Clin Exp Pediatr. 1990;33(7):907-914. Published online July 31, 1990
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A clinical study was performed on 26 cases of pulmonary air leaks in the newborn who were
admitted to the NICU of National Medical Center from Jan. 1984 to Aug. 1988
The results were as follows:
1) Spontaneous air leaks were 2 cases (7.7%)and secondary air leaks were 24 cases (92.3%).
2) Of the 26 cases of pulmonary air leaks, 13 cases (50.0%) had meconium aspiration... |
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- Clinical Studies on Congenital Anomalies.
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Hyeon Joo Chai, Kyung Hee Kim
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Clin Exp Pediatr. 1990;33(6):754-761. Published online June 30, 1990
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Modem medical science has been developed advanced rapidly in the past years, but congenital
anomalies are known as a major cause of neonatal death.
So, we studied the incidence of congenital malformations among 11,119 babies deliveried or
admitted at EWUH during a period of five years starting from June 1983.
The results were as follows:
1) The incidence of congenital malformations among 11,119 deliveries was 1.5%(1.5%... |
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- A Case of Transient Myeloproliferative Disorder in Down's Syndrome.
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Ji Hye Kang, Young Mi Hong, Kyung Hee Kim, Seung Joo Lee, Ki Sook Hong, Ok Kyung Kim, Je Geun Chi
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Clin Exp Pediatr. 1990;33(2):252-258. Published online February 28, 1990
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Transient myeloproliferative disorder has been reported in infant with Down's syndrome during
neonatal period.
This is clinically and hematologically indistinguishable from congenital acute leukemia. In contrast
to congenital leukemia, complete clinical and hematological recovery occurs within weeks to months
of diagnosis without antileukemic treatment.
A neonate presented with jaundice, hepatosplenomegaly and mongoloid face was diagnosed as
Transient myeloproliferative disorder.
We report this case with a review of... |
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- Colonization Factor Antigens of Heat-stable Enterotoxin-Producing (STf) E. Coli in Korean Children.
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Kon Hee Lee, Kyung Hee Kim, Yang Ja Cho
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Clin Exp Pediatr. 1989;32(9):1210-1215. Published online September 30, 1989
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Enterotoxigenic Escherichia coli (ETEC) cause an acute cholera-like diarrhea in both human and
animals. The disease process involves colonization of the mucosal surfaces of the small intestine
followed by elaboration of ST and/or heat-labile enterotoxin (LT). Intestinal colonization by ETEC
is mediated by specific surface-associated fimbrial or fibrillar antigens including colonization factor
antigens (CFA) I and II.
Isolates of E. coli from 114 children with... |
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- Factors Associated with Pneumothorax in Hyaline Membrane Disease In fants Receiving Mechanical Ventilation.
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Oh Kyung Lee, Kyung Hee Kim, Kyu Sun Choi, Wan Seoub Kim
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Clin Exp Pediatr. 1989;32(12):1642-1649. Published online December 31, 1989
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We observed 42 cases of neonates, who were diagnosed as having Hyaline membrane disease and
had been received mechanical ventilation in neonatal intensive care unit of Presbyterian medical
center from July 1984 to July 1988.
In order to observe the factors associated with pneumothorax, we devide these cases in two groups.
First group was consists of infants with pneumothorax, second group was consists of... |
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- A case of Dandy-Walker syndrome.
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Kyung Hee Kim, Jong Leam Choi, Hyo Sook Hong, Wan Seop Kim
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Clin Exp Pediatr. 1989;32(11):1586-1591. Published online November 30, 1989
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Dandy-Walker syndrome is a developmental disorder of the brain associated with hydrocephalus,
possterior fossa cyst and maldevelopment of the cerebellar vermis and is a result of outlet obstruction
of the fourth ventricle.
We experienced a case of a 6 day old male neonate who presented macrocephaly which revealed
marked dilated fourth & lateral ventricle, large posterior fossa cyst and hypoplastic cerebellum, no
vermis on Brain... |
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- A Case of Cockayne Syndrome.
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Jong Leam Choi, Kyung Hee Kim, Hyo Sook Hong, Wan Soeb Kim
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Clin Exp Pediatr. 1989;32(10):1422-1427. Published online October 31, 1989
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We experienced a case of Cockayne syndrome in a 12 10/12 year-old male who had characteristic
manifestations with cachectic dwarfism, severe mental retardation, intracranial calcifications, an
unusal face, photo-sensitive dermatitis and joint flexion contractures.
Laboratory investigations have not revealed any consistent abnormality.
We report this case with brief review of some related literatures. |
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- A Case of Glanzmann's Thromboasthenia.
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Hee Kyung Park, Kyung Hee Kim, Sang Man Shin, Sang Jhoo Lee
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Clin Exp Pediatr. 1987;30(2):223-228. Published online February 28, 1987
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Glanzmann’s Thromboasthenia is a rare autosomal recessive hemorrhagic disorder characterized
by chronic nonthrombocytopenic purpura, a prolonged bleeding time, and deficient or absent clot
retraction. The major underlying abnormality is defective first phase aggregation of platelets, which
are unresponsive to ADP in any concentration.
The authors experienced one case of Glanzmann’s Thromboasthenia in a 8 year 10 month old
female, who had frequent epistaxis and gingival... |
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- Case Report
- A Case of Iatrogenic Femoral Arteriovenous Fistula.
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Kyung Hyo Kim, Moon Ja Kim, Kyung Hee Kim, Keun Lee
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Clin Exp Pediatr. 1986;29(9):999-1001. Published online September 30, 1986
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Arteriovenous fistula is an abnormal vascular structure that establishes a communication
between an artery and a vein without the interposition of the capillary bed. We experienced a case of
iatrogenic femoral arteriovenous fistula in a six month-old girl. She was admitted with the chief complaint of different size of both lower leg which was first noted about l?/2 months PT A.... |
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- A Case of Marfan Syndrom.
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Kyung Hee Kim, Bok Lyun Kim, Chang Hwi Kim, Sang Jhoo Lee
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Clin Exp Pediatr. 1986;29(8):912-917. Published online August 31, 1986
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The Marfan syndrome is a heritable disorder of connective tissue with cardinal manifestations
in the ocular, skeletal and cardiovascular system. We experienced one case of Marfan syndrome
in 13-year-old girl who showed dolichostenomelia, scoiosis, ectopia lentis and mitral valve prolapse.
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- Abdominal Pain, Suspicious Peptic Ulcer and Psychologic Problem.
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Kwang Sin Joh, Chang Hyun Yang, Yong Back Kwon, Ki Sup Chung, Duk Jin Yun, Kyung Hee Kim
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Clin Exp Pediatr. 1986;29(4):426-430. Published online April 30, 1986
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Recurrent Abdominal Pain is a frequent disease entity in school children. It is characterized by at least three attacks of pain, sever enough to affect routine activity and occuring over a period of time longer than 3 months. The cause of the pain is almost psychophysiologic origin (over 95% of all children with recurrent abdominal pain). The frequency of this... |
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- 2 Cases of Herpes Simplex Virus Infection in the neonates.
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Kyung Hyo Kim, Jeong Wan Seo, Kyung Hee Kim, Keun Lee, Ki Sook Hong, Mi Ae Lee, Woon Sup Han, Ok Kyung Kim, Yung Oh Shin, Sung Bok Paik
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Clin Exp Pediatr. 1986;29(1):101-107. Published online January 31, 1986
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Herpes simplex virus infection in the newborn is generally thought to be associated with a grave prognosis
in terms of mortality and severe neurologic sequelae among survivors. Most neonatal herpes infection are
due to type 2 herpes virus hominis, acquired either by ascending infection from the mother’s genital area to the intrauterine infant after premature rupture of membrame, or by... |
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- Original Article
- Clinical Observation on Very Low Birth Weight Infants.
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Ran Ah Kim, Yeong Jee Kim, Kyung Hee KIm, Keun Lee
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Clin Exp Pediatr. 1986;29(1):26-31. Published online January 31, 1986
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Charts of very low birth weight infants weighing less than 1,500 grams at birth were reviewed and the results analyzed. Infants were 107 in numbers, admitted to NICU, Ewha Womans University Hospital for the period of
4 years from July 1980 to June 1984 including outborns. Results were as follows:
1) Incidence of very low birth weight infant was 1.... |
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- Case Report
- A case of Twin to Twin Transfusion Syndrome.
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Ja Young Park, Kyung Hee Kim, Chul Kyu Kim
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Clin Exp Pediatr. 1980;23(5):396-399. Published online May 15, 1980
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A case of twin to twin transfusion syndrome, associated with monozygotic twin fwas presented At birthm twin A weighted 2900gm and was plethoric, Hemoglobin value of twin A was 20.4gm/100ml and hematocrit 61% Twin B weighted 2250gm and was markedly pale, cynotic and hemoglobin value at virth was 4.3gm/100ml and hematocrit 13% So venesection by use of femoral venipuncture was... |
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