- Review Article
- General Pediatrics
- Korean Developmental Screening Test for Infants and Children (K-DST): development, applications, and implications for future early childhood development interventions
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Dooyoung Kim, Young June Choe, Bilal Aurang Zeb Durrani, EunYoung Kim, Junghye Byeon, Baik-Lin Eun
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Clin Exp Pediatr. 2023;66(7):288-293. Published online December 22, 2022
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· This review discusses the development and application of the Korean Developmental Screening Test for Infants and Children (K-DST) for ensuring early childhood development.
· Various studies have demonstrated the integral role of the K-DST in facilitating the detection of developmental delays and delivery of timely interventions.
· The tailoring of the K-DST to Korean infants and children suggests that other countries may further translate and adapt it. |
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- Original Article
- Developmental and Behavioral Medicine
- Development of the Korean Developmental Screening Test for Infants and Children (K-DST)
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Hee Jung Chung, Donghwa Yang, Gun-Ha Kim, Sung Koo Kim, Seoung Woo Kim, Young Key Kim, Young Ah Kim, Joon Sik Kim, Jin Kyung Kim, Cheongtag Kim, In-Kyung Sung, Son Moon Shin, Kyung Ja Oh, Hee-Jeong Yoo, Hee Joon Yu, Seoung-Joon Lim, Jeehun Lee, Hae-Ik Jeong, Jieun Choi, Jeong-Yi Kwon, Baik-Lin Eun
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Clin Exp Pediatr. 2020;63(11):438-446. Published online May 14, 2020
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Question: Can the Korean Developmental Screening Test for Infants and Children (K-DST) be a useful screening tool for infants and children in Korea?
Finding: The K-DST has high reliability (internal consistency of 0.73–0.93, test-retest reliability of 0.77–0.88) and a high discriminatory ability with a sensitivity of 0.833 and specificity of 0.979.
Meaning: The K-DST is an effective and reliable screening tool for infants and children with neurodevelopmental disorders in Korea. |
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- Original Article
- Developmental and Behavioral Medicine
- Usefulness of the Korean Developmental Screening Test for infants and children for the evaluation of developmental delay in Korean infants and children: a single-center study
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Chung-Hyuk Yim, Gun-Ha Kim, Baik-Lin Eun
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Clin Exp Pediatr. 2017;60(10):312-319. Published online October 20, 2017
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Purpose To evaluate the usefulness of the Korean Developmental Screening Test (K-DST) for infants and children for developmental delay assessment. MethodsThis study was based on retrospective studies of the results of the K-DST, Preschool Receptive-Expressive Language Scale (PRES), Sequenced Language Scale for Infants (SELSI), Childhood Autism Rating Scale (CARS), Modified Checklist for Autism in Toddlers (M-CHAT), electroencephalography, magnetic resonance imaging, and extensive... |
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- Case Report
- Neurology
- Chromosome 11q13 deletion syndrome
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Yu-Seon Kim, Gun-Ha Kim, Jung Hye Byeon, So-Hee Eun, Baik-Lin Eun
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Clin Exp Pediatr. 2016;59(Suppl 1):S10-S13. Published online November 30, 2016
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Chromosome 11q13 deletion syndrome has been previously reported as either otodental syndrome or oculo-oto-dental syndrome. The otodental syndrome is characterized by dental abnormalities and high-frequency sensorineural hearing loss, and by ocular coloboma in some cases. The underlying genetic defect causing otodental syndrome is a hemizygous microdeletion involving the FGF3 gene on chromosome 11q13.3. Recently, a new form of severe deafness,... |
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- Ictal sinus pause and myoclonic seizure in a child
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Hye Ryun Kim, Gun-Ha Kim, So-Hee Eun, Baik-Lin Eun, Jung Hye Byeon
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Clin Exp Pediatr. 2016;59(Suppl 1):S129-S132. Published online November 30, 2016
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Ictal tachycardia and bradycardia are common arrhythmias; however, ictal sinus pause and asystole are rare. Ictal arrhythmia is mostly reported in adults with temporal lobe epilepsy. Recently, ictal arrhythmia was recognized as a major warning sign of sudden unexpected death in epilepsy. We present an interesting case of a child with ictal sinus pause and asystole. A 27-month-old girl was... |
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- Original Article
- Neurology
- Epilepsy in children with a history of febrile seizures
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Sang Hyun Lee, Jung Hye Byeon, Gun Ha Kim, Baik-Lin Eun, So-Hee Eun
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Clin Exp Pediatr. 2016;59(2):74-79. Published online February 29, 2016
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Purpose Febrile seizure, the most common type of pediatric convulsive disorder, is a benign seizure syndrome distinct from epilepsy. However, as epilepsy is also common during childhood, we aimed to identify the prognostic factors that can predict epilepsy in children with febrile seizures MethodsThe study comprised 249 children at the Korea University Ansan Hospital who presented with febrile seizures. The relationship between... |
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- Single-center experience of the Korean-Developmental Screening Test for infants and children
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Chae-Ri Suh, Su Ye Sohn, Gun-Ha Kim, Seong-Kwan Jung, Baik-Lin Eun
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Clin Exp Pediatr. 2016;59(12):483-489. Published online December 31, 2016
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Purpose We investigated the number of test takers of the Korean-Developmental Screening Test (K-DST) in a single children's hospital within a year, according to age, referral rate, and follow-up percentage. MethodsFor this study, 4,062 children who visited and received K-DST at Woorisoa Children's Hospital between January and December 2015 were enrolled. Seven test sets were used according to the Korean National Health... |
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- Analysis of clinical information and reverse transcriptase-polymerase chain reaction for early diagnosis of enteroviral meningitis
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Dahee Jin, Tae Hoon Heo, Jung Hye Byeon, Gun-Ha Kim, Mi Kyung Kim, So-Hee Eun, Baik-Lin Eun
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Clin Exp Pediatr. 2015;58(11):446-450. Published online November 22, 2015
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Purpose Meningitis is among the most common infections affecting the central nervous system. It can be difficult to determine the exact pathogen responsible for the infection and patients are often treated with empiric antibiotics. This study was conducted to identify the most common clinical characteristics of enteroviral meningitis in children and evaluate the diagnostic efficacy of reverse transcriptase-polymerase chain reaction (RT-PCR)... |
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- The current child and adolescent health screening system:
an assessment and proposal for an early and periodic check-up program
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Baik-Lin Eun, Jin Soo Moon, So-Hee Eun, Hea Kyoung Lee, Son Moon Shin, In Kyung Sung, Hee Jung Chung
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Clin Exp Pediatr. 2010;53(3):300-306. Published online March 15, 2010
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Purpose : Recent changes in the population structure of Korea, such as rapid decline in birth rate and exponential increase in old-aged people, prompted us to prepare a new health improvement program in children and adolescents.
Methods : We reviewed current health screenings applied for children and adolescents in Korea and other developed countries. We collected and reviewed population-based data... |
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- One-year evaluation of the national health screening program for infants and children in Korea
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Jin Soo Moon, Soon Young Lee, Baik-Lin Eun, Young Key Kim, Young Key Kim, Son Moon Shin, Hea Kyoung Lee, Hee Jung Chung
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Clin Exp Pediatr. 2010;53(3):307-313. Published online March 15, 2010
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Purpose:Results of the Korea National Health Screening Program for Infants and Children, which was launched in November 2007, were evaluated for future research and policy development.
Methods:Data from a total of 2,729,340 cases were analyzed. Five visiting ages, such as 4, 9, 18, 30, and 60 months, were included. Several parameters such as stunting, obesity, and positive rate of developmental... |
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- Review Article
- Treatment and prognosis of neonatal seizures
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So-Hee Eun, Baik-Lin Eun
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Clin Exp Pediatr. 2009;52(9):971-975. Published online September 15, 2009
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Seizures in the neonatal period are common and frequently indicate serious underlying brain injury. Neonatal seizures continue to present a diagnostic and therapeutic challenge to pediatricians because recognition and classification of neonatal seizures remain problematic, particularly when clinicians rely only on clinical criteria. Neonatal seizures can permanently disrupt neuronal development, induce synaptic reorganization, alter plasticity, and "prime" the brain to... |
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- Original Article
- Functional recovery after transplantation of mouse bone marrow-derived
mesenchymal stem cells for hypoxic-ischemic brain injury in immature rats
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Wooksun Choi, Hye Kyung Shin, So-Hee Eun, Hoon Chul Kang, Sung Won Park, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Baik-Lin Eun
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Clin Exp Pediatr. 2009;52(7):824-831. Published online July 15, 2009
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Purpose : We aimed to investigate the efficacy of and functional recovery after intracerebral transplantation of different doses of mouse mesenchymal stem cells (mMSCs) in immature rat brain with hypoxic-ischemic encephalopathy (HIE).
Methods : Postnatal 7-days-old Sprague-Dawley rats, which had undergone unilateral HI operation, were given stereotaxic intracerebral injections of either vehicle or mMSCs and then tested for locomotory activity in... |
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- Case Report
- Two cases of Smith-Magenis syndrome
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Seong Kwan Jung, Kyu Hee Park, Hae Kyung Shin, So Hee Eun, Baik-Lin Eun, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Sook Young Bae
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Clin Exp Pediatr. 2009;52(6):701-704. Published online June 15, 2009
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SmithMagenis syndrome (SMS) is a rare disorder with multiple congenital anomalies caused by a heterozygous interstitial deletion involving chromosome 17p11.2, where the retinoic acid-induced 1 (RAI1) gene is located, or by a mutation of RAI1. Approximately 90% of the patients with SMS have a detectable 17p11.2 microdeletion on fluorescence in-situ hybridization (FISH). SMS is characterized by mental retardation, distinctive behavioral... |
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- Review Article
- Attention deficit hyperactivity disorder
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So-Hee Eun, Baik-Lin Eun
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Clin Exp Pediatr. 2008;51(9):935-943. Published online September 15, 2008
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Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder characterized by a persistent pattern of inattention and/or hyperactivity, as well as forgetfulness, poor impulse control or impulsivity, and distractibility. The recommended evaluation includes documenting the type and severity of ADHD symptoms, verifying the presence of normal vision and hearing, screening for comorbid psychological conditions, reviewing the child`s developmental history... |
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- A suggestion of health insurance for children
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Baik-Lin Eun
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Clin Exp Pediatr. 2008;51(4):339-342. Published online April 15, 2008
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The Korean Health Insurance (KHI) has been introduced since 1977 and it took only 12 years that KHI had accomplished the total coverage of Korean population. The remarkable success of KHI can be compared with other OECD countries which had taken some 30 years to over 100 years to establish the total coverage of the population. Life expectancy at birth... |
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- Original Article
- Use of herbal medicine in epileptic children
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Jee Yeon Lee, Wook Sun Choi, So-Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2008;51(4):415-419. Published online April 15, 2008
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Purpose : Herbal medicine is thought to be widely used by children with epilepsy, but there have been few studies. This study aimed to investigate the perceptions and the actual conditions of usage of herbal medicine by children with epilepsy.
Methods : From July to August 2007, three hundred seventy eight questionnaires were completed by parents of epileptic children who visited... |
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- Review Article
- Overview of the national health screening program for infant and children
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Baik-Lin Eun, Seong Woo Kim, Young Key Kim, Jung Wook Kim, Jin Soo Moon, Su Kyung Park, In Kyung Sung, Son Moon Shin, Sun Mi Yoo, So Hee Eun, Hea Kyoung Lee, Hyun Taek Lim, Hee Jung Chung
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Clin Exp Pediatr. 2008;51(3):225-232. Published online March 15, 2008
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The mission of National Health Screening Program for Infant and Children is to promote and improve the health, education, and well-being of infants, children, families, and communities. Although the term 'diagnosis' usually relates to pathology, a similar diagnostic approach applies to the child seen primarily for health supervision. In the case of health, diagnosis determines the selection of appropriate health... |
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- Original Article
- A survey of body shape perception and weight control of
adolescent girls in three areas of Korea
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Yoon Lee, Hye-Kyoung Shin, Byung-Min Choi, Baik-Lin Eun, Sang-Hee Park, Kee-Hyoung Lee, Chol Shin
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Clin Exp Pediatr. 2008;51(2):134-144. Published online February 15, 2008
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Purpose : This study aimed to investigate body shape perception, weight control behaviors and eating habits of adolescent girls in urban, suburban and rural areas of Korea to obtain basis for establishing adequate weight control program for adolescent.
Methods : From May 2002 to November 2002, a cross-sectional questionnaire survey and physical examination were conducted to examine body shape perception, weight... |
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- Efficacy and safety of oxcarbazepine in epileptic children
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Hye Kyung Shin, Yoon Lee, Jee-Yeon Lee, Wooksun Choi, So-Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2008;51(2):162-169. Published online February 15, 2008
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Purpose : Oxcabarzepine (OXC), newly recommended antiepileptic drug, has been prescribed for patients with partial seizures and generalized tonic clonic seizures in Korea from 1999. There are limited reports about an efficacy of OXC therapy in epileptic children in Korea. This study evaluated the efficacy and safety of OXC in the light of our experience.
Methods : The patients, who had... |
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- A pilot study of neuroprotection with umbilical cord blood cell transplantation for preterm very low birth weight infants
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Kyu Young Chae, Kyu Hyung Lee, So-Hee Eun, Byung Min Choi, Baik-Lin Eun, Hoon-Chul Kang, Myung Jae Chey, Nam Keun Kim, Doyeun Oh
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Clin Exp Pediatr. 2007;50(9):882-890. Published online September 15, 2007
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Purpose : Preterm very low birth weight infant have high rate of adverse neurodevelopmental sequale. Recently, there have been lots of reports that human umbilical cord blood transplantation ameliorates functional deficits in animal models as hypoxic ischemic injury. This pilot study was undertaken to determine the clinical efficacy and safety of autologous umbilical cord blood cell transplantation for preventing neurodevelopmental... |
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- Case Report
- Clinical improvement in a case of atypical infantile onset Pompe disease with enzyme replacement therapy
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You Hoon Jeon, Baik-Lin Eun, Chang Sung Son, Dong Hwan Lee
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Clin Exp Pediatr. 2007;50(2):213-217. Published online February 15, 2007
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Pompe disease is a genetic disorder caused by a deficiency of acid α-glucosidase (GAA). Infantile onset Pompe disease is uniformly lethal. Affected infants generally present in the first few months of life with hypotonia, generalized muscle weakness, and a hypertrophic cardiomyopathy, which is rapidly followed by death, usually by the age of one. The late-onset form is characterized less severe... |
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- Original Article
- Usefulness of tibia counter rotator (TCR) for treatment of tibial internal torsion in children
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Dong Ho Song, Yoon Lee, Baik-Lin Eun, Kwang Jae Lee, Sang Kuk Kang, Sung Gin Vaq, Sung You, Jung Bin Shin, Bong Ok Kim
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Clin Exp Pediatr. 2007;50(1):79-84. Published online January 15, 2007
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Purpose : Tibial internal torsion is prevalent in East Asian countries such as Korea and Japan, where sitting on the floor is common behavior. Tibial internal torsion or excessive lateral tibial torsion may cause esthetical, functional, or psychological problems and also may induce degenerative arthritis in older age. The aim of this study is to evaluate the therapeutic effect of... |
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- Case Report
- Primary peritoneal drainage as a treatment for perforated necrotizing enterocolitis with bacterial peritonitis in an extremely low birth weight infant : a case report
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Wook Sun Choi, Il Hong Moon, Jang Hoon Lee, Seung Hwa Lee, Byung Min Choi, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(7):800-804. Published online July 15, 2006
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Necrotizing enterocolitis(NEC) is the most common life-threatening surgical emergency in neonates, and remains a major cause of morbidity and mortality. In addition to conventional laparotomy, intraperitoneal drains have been used for the treatment of perforated NEC, especially in extremely low birth weight(ELBW) infants. We report a case of perforated NEC with bacterial peritonitis in an ELBW infant managed with primary... |
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- Review Article
- Headaches in children and adolescents : diagnosis and treatment
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So Hee Eun, Baik-Lin Eun
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Clin Exp Pediatr. 2006;49(4):354-363. Published online April 15, 2006
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Headaches are common in children and become more common and increase in frequency during adolescence. There are various causes of headaches. The majority of cases are considered as primary and include migraine and tension headaches. The rational evaluation of headache begins with careful history. Migraine is genetically determined recurrent pain syndrome accompanied by neurological and gastrointestinal features, involving interaction of... |
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- Original Article
- The auditory evoked potential in premature small for gestational age infants
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Il Hong Moon, Kee Soo Ha, Gui Sang Kim, Byung Min Choi, Baik-Lin Eun, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(12):1308-1314. Published online December 15, 2006
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Purpose : This study aimed to evaluate the usefulness of auditory evoked potential (AEP) in clarifying neuronal development in premature small for gestational age (SGA), and appropriate for gestational age (AGA) infants.
Methods : A total of 183 premature infants who were born from August 2002 to July 2005, were examined with AEP. They were divided into three groups; AGA, symmetric-SGA... |
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- The effects of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants
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Wooksun Choi, Jung-Yeon Shin, Byung Min Choi, Baik-Lin Eun, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(12):1315-1323. Published online December 15, 2006
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Purpose : This study was conducted to compare the efficacy and safety of ibuprofen and indomethacin in the treatment of patent ductus arteriosus (PDA) in preterm infants and to determine whether ibuprofen can be an alternative drug.
Methods : A total of 32 preterm infants with symptomatic PDA were enrolled in the study. Twelve infants received intravenous ibuprofen 10 mg/kg, followed... |
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- Usefulness of modified ambu in patients who need artificial ventilation
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Kee Soo Ha, Il Hong Moon, Hee Sun Lee, Dong Han Shin, So Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(11):1194-1201. Published online November 15, 2006
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Purpose : The comatose mentality can be catastrophic, especially if the condition is severe or the duration is prolonged. Therefore, delayed diagnosis can result in a poor outcome or death. The best radiologic modality to differentiate from cerebral lesions in patients suffering from cerebral diseases is magnetic resonance imaging (MRI) rather than computed tomography (CT). Special apparatuses with metal... |
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- Usefulness of Korean Infant Developmental Screening Test in Premature Infants
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Dong Han Shin, Hee Sun Lee, Jee Yeon Lee, Byung Min Choi, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2005;48(12):1337-1341. Published online December 15, 2005
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Purpose : This study aimed to evaluate the usefulness of Korean Infant Development Screening Test in predicting delayed development in premature infants.
Methods : A total of 74 children with histories of prematurity, who visited the pediatric neurology clinic of Korean University Ansan Hospital from August, 2002 to July, 2004, were examined, using the Korean Infant Development Screening Test. They were... |
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- Tibial Torsion in Children of the Jeju Area
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Dong Ho Song, Baik-Lin Eun, Sang Hee Park, Joon Young Lee, Young Chang Tockgo
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Clin Exp Pediatr. 2005;48(1):75-80. Published online January 15, 2005
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Purpose : Internal tibial torsion is prevalent in East Asian countries such as Korea and Japan, where sitting on the floor is common behavior. Internal tibial torsion or excessive lateral tibial torsion may cause esthetical, functional, or psychological problems and also may induce degenerative arthritis in older age. The purpose of this study is to measure the tibial torsion in... |
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- Serum Lipids of School Children and Adolescence in Urban and Rural Area
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Dong Han Shin, Hee Sun Lee, Kee Hyoung Lee, Baik-Lin Eun, Chae Seung Lim, Young Chang Tockgo
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Clin Exp Pediatr. 2004;47(12):1273-1280. Published online December 15, 2004
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Purposes : A cross-sectional study on serum lipids in school children and adolescents was carried out in two different areas in 2002. We studied to determine of the difference in lipids level of children between urban and rural areas and changes of cholesterol levels compared to those of early- 1990 studies.
Methods : A cross-sectional study on serum lipids in school... |
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- Efficacy of Antiepileptic Drug on the Benign Childhood Epilepsy with Centro-Temporal Spikes
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Mee Hye Oh, Soo Young Kim, Won Hee Seo, Dae Hun Pee, Byung Min Choi, Baik-Lin Eun
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Clin Exp Pediatr. 2003;46(9):893-897. Published online September 15, 2003
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Purpose : Benign childhood epilepsy with centrotemporal spikes(BECT) is characterized by an excellent prognosis. Therefore, the necessity for the use of antiepileptic drugs is controversial. The object of this study is to know about the long-term follow-up of BECT, comparing daily treatment with antiepileptic drug(AED) versus no medication.
Methods : We retrospectively studied 56 cases of BECTs, examined at Pediatric Neurology... |
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- Case Report
- A Case of Melkersson-Rosenthal Syndrome
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Dae Hun Pee, Yo Won Na, Ki Young Chang, Woo Keun Seo, Kee Hyoung Lee, Baik-Lin Eun
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Clin Exp Pediatr. 2002;45(10):1292-1297. Published online October 15, 2002
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Melkersson-Rosenthal syndrome(MRS) is a rare disorder, having a symptom triad of recurrent facial
palsy, orofacial swelling and fissured tongue(lingua plicata). This disorder is usually recurrent
or progressive, and monosymptomatic or oligosymptomatic forms have been reported to be more
common than classic forms. Generally, MRS occurs in young adults at the end of the second
decade of life and incidence of the disease in childhood... |
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- Original Article
- The State of Smoking and Alcohol Usein Korean Adolescent
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Gi Chan Lee, Young Joon Kim, Young Kyoo Shin, Baik-Lin Eun, Sang Hee Park, Young Chang Tockgo
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Clin Exp Pediatr. 1997;40(3):307-317. Published online March 15, 1997
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Purpose : Recently, smoking and alcohol use in adolesecnt have increased and it has
been a social issue in Korea.This study was performed to understand the state of
smoking and alcohol use in Korean adolescents, and to make abasic data for education
of them.
Methods : This study was carried in 1994.3,360 students in 13 schools aged from 13
to 18 were enrolled in this... |
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- Detection of Mycoplasma pneumoniae in clinical Samples from Pediatric Patients by Polymerase Chain Reaction
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Baik-Lin Eun, Sang Hee Park, Young Chang Dockgo, Sang Chul Seong
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Clin Exp Pediatr. 1995;38(8):1077-1086. Published online August 15, 1995
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Purpose : Mycoplasma pneumoniae is a common cause of a wide rage of upper and lower respiratory tract infections, especially in children and young adults. Routine laboratory diagnosis of M.pneumoniae infection is based mainly on serology and, to lesser extent, on cultivation. The cultivation of M.pneumoniae, a fastidious microorganism, is time-consuming and may require 1-3 weeks for results. Serological procedures... |
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