| Efficacy of Antiepileptic Drug on the Benign Childhood Epilepsy with Centro-Temporal Spikes |
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Mee Hye Oh, Soo Young Kim, Won Hee Seo, Dae Hun Pee, Byung Min Choi, Baik-Lin Eun |
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Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea |
| 중심-측두엽 극파를 보이는 양성 소아 간질 환자에서항경련제 투여의 유효성 |
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오미혜, 김수영, 서원희, 피대훈, 최병민, 은백린 |
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고려대학교 의과대학 소아과학교실 |
Correspondence:
Baik-Lin Eun, Email: bleun@chol.com
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| Abstract |
Purpose
: Benign childhood epilepsy with centrotemporal spikes(BECT) is characterized by an excellent prognosis. Therefore, the necessity for the use of antiepileptic drugs is controversial. The object of this study is to know about the long-term follow-up of BECT, comparing daily treatment with antiepileptic drug(AED) versus no medication.
Methods
: We retrospectively studied 56 cases of BECTs, examined at Pediatric Neurology Clinic, Korea University Medical Center as reference study time, August 2002. Thirty-eight patients didn't have mediation(group I), while eighteen patients received one or two AED(group II). We evaluated demographics, clinical manifestations at diagnosis, EEG findings and clinical courses in groups I & II.
Results
: There was no significant differences of sex, age, seizure frequency, seizure type, seizure onset time, family history and EEG findings between group I & II. The reasons to start AED were : parents' anxiety(three cases), frequent seizure(12 cases) and daytime seizure(three cases). There was no evolution of status epilepticus and no difficulty in school performance.
Conclusion
: AED treatment was of no advantage and long-term prognosis was good regardless of treatment strategy. So it is advisable not to choose AED as the first line of therapy, provided that the patient himself/herself or the family understands the benign nature of BECT. |
| Key Words:
Antiepileptic drug, Benign childhood epilepsy with centro-temporal spikes |
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