| Purpose : We have assessed the clinical usefulness of solid maker transit technique and Barr-score in 31 patients with idiopathic constipation (male:female; 17:14, mean age; 6.7 years, range 1.4-12 years). Methods : All patients underwent full history taking and physical examination including rectal examination. On first visit to gastroenterology clinic a plain abdominal film was taken for Barr-score which evaluated by two observers without the... |
| Purpose : The aim of this study is to evaluate the influence of the feeding (fastingpostprandial) and the state of alertness(awake-asleep) on the amount of gastroesophageal reflux by using 24hour esophageal pH metry. Methods : From July 1994 to June 1995, 32 cases of 24 hour esophageal pH metry had been done at the Asan Medical Center. Twenty three children with normal pH monitoring and... |
| Purpose : Patent ductus arteriosus(PDA) is a common disease in very low birth weight infants(VLBWI). Hemodynamically significant PDA increases the morbidity and mortality of premature infants. Based on experimental model, light inhibits the constriction of immature piglet' s ductal rings. No specific mechanism adequately explains the effect of light on the relaxation of PDA. Several hypotheses, including activation of photosensitive metabolites, alterations in receptors, or... |
| Purposes : Nitric oxide(NO) is classified as toxic gas in native states, but in most biologic systems NO acts as a messenger molecule. NO is known as endothelium derived relaxing factor that modulates tone of vascular smooth muscle. Inhaled NO has been reported to act as a selective pulmonary vasodilator and we expect that NO inhalation can be used as a successful treatment modality... |
| Purpose : This study was designed to evaluate the incidence of complication in severely obese children and to determine whether the difference of Lp(a) between severely obese children and normal control group exists. Methods : Body weight, height and obesity index were measured in 5885(M:F= 3089:2796) elementary school children. Eight eight(M:F=63:25) were selected as severely obese children. Of the 88 children, 74 agreed to venous... |
| Purpose : School-based violence among adolescents is a serious public health problem. Recently, it seems to spread and intensify. We were trying to investigate the information about adolescent' s experience, witness and perception in violence, thus to offer the data for appropriate violence prevention methods on our circumstance. Methods : During July, 1996, 3,794 middle or high school students in the metropolitan area of Korea... |
| Purpose : There were rapid socio-environmental changes in Korea caused by industrializations in last thirty years. Those changes are : first, abrupt changes from the environments with closed Confucian ideas to the liberal democratic society, second, agricultural society changed to industrialized society and families with two or three generations are broken down into nuclear families at each generation, third, the annual personal income was... |
| Purpose : The urinary mass screening program for the detection of proteinuria had been performed for a school age population in the city of Seoul since 1981. However, systematic evaluation for this program had never been done. We, therefore, designed a systematic evaluation in corporation with the Seoul School Health Center for students with proteinuria identified in the mass screening to determine the prevalence... |
| Purpose : Considering that renal biopsy is not routinely indicated in nephrotic syndrome in children and the risk of the procedure, we studied that it is possible to predict steroid responsiveness in nephrotic syndrome and the difference in responsivenss is related with the histopathologic type using urinary β2-microglobulin and N-Acetyl-β-D-Glucosaminidase activity as a safe and noninvasive method. Methods : We measured serum creatinine, albumin, cholesterol... |
| Purpose : The aim of the present study was to assess the clinicopatholgical significance of Bcl-2 oncoprotein expression in childhood non-Hodgkin' s lymphoma(NHL). Methods : We have assessed 16 cases of childhood NHL during last 6 years from 1990 to 1995. Bcl-2 oncoprotein expression has been semiquantitatively analyzed in paraffin sections from 16 cases of childhood NHL with 39 control cases of adult NHL. The... |
| Purpose : Although the data of radiofrequency catheter ablation(RFCA) of supraventricular tachycardia in adults has been accumulated in several centers in Korea, few data are available on its efficacy and safety in pediatric ages. We reviewed the data in young patients who underwent this procedure in a pediatric cardiology center, to evaluate the indications, early results, complications, and short-term follow-up data. Methods : We retrospectively... |
| Purpose : There are controversies in the operative methods of aorta with ventricular septal defect in infancy. Recent results of single stage operation for coarctation of aorta with intracardiac defects were regarded as comparable to staged operation. We evaluated our interim results after single stage operation for coarctation of aorta with large ventricular septal defect in infancy. Methods : Twenty six infants who had received... |
| Purpose : Pulmonary function test is one of the most important tools in the management of patients with respiratory tract diseases and allergic diseases. In recent years pulmonary function tests have had a wide application in clinical pulmonary diseases. But, there were a few trials of pulmonary function test in normal children. So We performed spirometry-based pulmonary function tests of normal children. Methods : We... |
| Purpose : Pleural effusions may develop during the course of bacterial pneumonia. The aim of this study was to evaluate the significance of the polymerase chain reaction(PCR) method for detection of M ycoplasma pneumoniae, M ycobaterium tuberculosis and Staphylococcus aureus from pleural fluid. Methods : Total 12 samples were obtained from pleural fluid; 2 samples from children with Mycoplasma pneumonia, 5 samples from adults with... |
| Purpose : Theophylline, an adenosine antagonist commonly used in premature infants to treat apnea, has been shown to decrease erythropoietin levels in adults. We studied the effect of theophylline on serum erythropoietin levels in premature infants with apnea. Methods : Subject were 12 premature infants with apnea who were admitted to the NICU, Chosun University Hospital. The first dose of theophylline was 5mg/kg, given... |
| Purpose : The visual evoked potentials(VEPs) offer a window both on visual system function and on cerebral or neurologic function. The study was performed to evaluate the maturation of VEP in preterm infants and to present a guide to detect high risk neonates who can develop neurodevelopmental abnormalities. Methods : The VEPs were recorded in response to binocular stimulus with light-emitting diode goggles. VEP recordings... |
| Purpose : Although neonatal intensive care and development of obstetrics play a role in improving survival rate in prematurity, cerebral palsy(CP) is still one of the neurologic sequelae. We tried to find what kinds of risk factors in the patients with abnormal neurosonographic findings who developed CP later. This study was performed to predict early enough who will develop CP later and to treat... |
| Purpose : To determine which perinatal risk factors influence neurodevelopmental outcome, we try to investigate which perinatal risk factors are correlated with Baley mental or psychomotor developmental index using BSID-Ⅱ test(Baley Scales of Infant Development, Ⅱ) in long term follow up of very low birth weight who received neonatal intensive care. Methods : This study was performed on 56 very low birth weight infants with... |
| Purpose : An excess of GH causes various problems within the cardiovascular system including cardiac hypertrophy and abnormalities of left ventricle(LV) function. To evaluate the cardiovascular effects due to GH treatment in idiopathic short stature (ISS), we measured the cardiovascular function. Methods : Twenty-two echocardiographic studies were performed in ISS who were admitted from Jan. 1994 through Jul. 1996, and they were divided into two... |
| Purpose : We studied prevention effects of vertical transmission of Hepatitis B with follow-up, through the change of Anti-HBs titers during 9 months after injection of Hepatitis B immunoglobulin(HBIG) and Hepatitis B vaccine(HBV) at birth in newborn delivered from Hepatitis antigen carrier mothers. Methods : This study was performed on newborn delivered from HBsAg carrier mothers at Hae Sung Hospital from Feb. 1995 to May... |
| Purpose : This study was carried out to evaluate the role of the septal leaflet of the tricuspid valve. The hypothesis was that the neonatal tricuspid regurgitation(TR) was related to a transient elevation of right ventricular pressure in the neonatal period, that deviated ventricular septum and pull the anchored septal leaflet of the tricuspid valve. The pulled septal leaflet created the incomplete coaptation between... |
| Purpose : Ugly ulcer and keloid formation of injection site has sometimes been a problem in Korea from the cosmetic point of view in intradermal vaccination. Since 3 or 4 years ago, multipuncture BCG vaccination has been used in Korea, there are no data and information about multipuncture BCG vaccination. We therefore performed this study to evaluate of conversion rate, complication and to make... |
| Purpose : Lipids and fatty acids are very important for brain and nervous system in growing children. This study was carried out to compare the composition of serum lipids and fatty acids according to the type of feeding in children. Methods : One hundred and twenty two children aged from 5 month to 24 month who visited Soonchunhyang University Hospital from Mar. 1995 to... |
| Purpose : Studies done in Western societies have described characteristics of infant crying behavior. These include:crying peak in the second month, diurnal rhythm(typified by clustering during evening hours) and crying that is robust to differences in caretaking styles. This survey was undertaken to compare the crying patterns of Korean babies with those of their Western counterparts. Methods : From June 1995 to March 1996, well... |
| Purpose : In the Summer 1996, there was an outbreak of aseptic meningitis without sequele. 116 cases who were admitted to our Department during a six month period from May to October, 1996. Therefore, we report epidemic of aseptic meningitis in 1996 and analyze and compare it with a epidemic of aseptic meningitis in 1993. Methods : We studies about clinical manefestation and laboratory finding... |
| Purpose : This is to analyze epidemic and clinical features of acute respiratory tract infections(ALRTI) by respiratory syncytial virus(RSV) and parainfluenza virus(PIV), which are considered to be the major respiratory pathogens in children. Methods : Nasopharyngeal aspirates were collected from 515 patients with ALRTI hospitalized at Hangang Sacred Heart Hospital between Apr. ’94 and Oct. ’96. Nasopharyngeal aspirates were inoculated to... |
| Purpose : The importance of trace elements in their effect on the physiology and pathology of the central nervous system is well recognized. Changes in the concentrations of these elements in the brain could take place in pathological states. Recently, a greater emphasis has been given to the role of trace elements in the function of the nervous system both in normal and pathological... |
| Purpose : Juvenile myoclonic epilepsy, juvenile absence epilepsy, and epilepsy wth generalized tonic clonic seizure(GTCS) on awakening are the three syndromes of idiopathic generalized epilepsy of adolescent onset currently included in the classification of epilepsy syndromes of the International League Against Epilepsy(ILAE). Although they differ in their predominant seizure types, the syndromes share several seizure types. Also, there are no unique electrophysiologic or genetic markers.... |
| Purpose : IL-1β and TNF-α are important mediators of the inflammatory response in serious bacterial infections. The mucosal and systemic IL-1β and TNF-α responses to urinary tract infection are analyzed in children with acute urinary tract infection. Methods : We studied the levels of these two cytokines in the urine and sera of 21 children at diagnosis and after treatment with sandwich ELISA method. Results... |
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