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Original Article
Constipation in Children-Colonic Transit Time and the Barr-Score
Nam-Seon Beck, I Sok Kang, Dong Kyu Jin, Munhyang Lee, Sang Il Lee, Heung Jae Lee, Bokyung Kim, Tae Sung Park
Clin Exp Pediatr. 1997;40(10):1427-1434.   Published online October 15, 1997
Purpose : We have assessed the clinical usefulness of solid maker transit technique and Barr-score in 31 patients with idiopathic constipation (male:female; 17:14, mean age; 6.7 years, range 1.4-12 years). Methods : All patients underwent full history taking and physical examination including rectal examination. On first visit to gastroenterology clinic a plain abdominal film was taken for Barr-score which evaluated by two observers without the...
Influence of Feeding and State of Alertness on the Incidence of Gastroesophageal Reflux in Children
Kyung Mo Kim, Jung Yeon Shim, Soo Jong Hong
Clin Exp Pediatr. 1997;40(10):1419-1426.   Published online October 15, 1997
Purpose : The aim of this study is to evaluate the influence of the feeding (fastingpostprandial) and the state of alertness(awake-asleep) on the amount of gastroesophageal reflux by using 24hour esophageal pH metry. Methods : From July 1994 to June 1995, 32 cases of 24 hour esophageal pH metry had been done at the Asan Medical Center. Twenty three children with normal pH monitoring and...
Influence of Phototherapy on Incidence of Patent Ductus Arteriosus in Very Low Birth W eight Infants
Hee Seok Kim, Ee Kyung Kim, Yun Kyoung Lee, Hee Eun Lee, Chan Hwu Park, Kyung Ran Park, Jun Dong Park, Beyong Il Kim, Woong Heum Kim, Jung-Hwan Choi, Yong Su Yun, Chong Ku Yun, Jeong Mi Lee
Clin Exp Pediatr. 1997;40(10):1410-1418.   Published online October 15, 1997
Purpose : Patent ductus arteriosus(PDA) is a common disease in very low birth weight infants(VLBWI). Hemodynamically significant PDA increases the morbidity and mortality of premature infants. Based on experimental model, light inhibits the constriction of immature piglet' s ductal rings. No specific mechanism adequately explains the effect of light on the relaxation of PDA. Several hypotheses, including activation of photosensitive metabolites, alterations in receptors, or...
Hemodynamic Effect of Nitric Oxide Inhalation in the Acute Hypoxic Pulmonary Hypertension Induced Newborn Piglet
Yun Cil Chang, Won Soon Park, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1997;40(10):1394-1409.   Published online October 15, 1997
Purposes : Nitric oxide(NO) is classified as toxic gas in native states, but in most biologic systems NO acts as a messenger molecule. NO is known as endothelium derived relaxing factor that modulates tone of vascular smooth muscle. Inhaled NO has been reported to act as a selective pulmonary vasodilator and we expect that NO inhalation can be used as a successful treatment modality...
Complications, Apolipoproteins and Lipoprotein(a) in Severely Obese Children in Incheon, 1996
Yon Ho Choe, Yong Hoon Jun, Soon Ki Kim, Seung Kyu Han, Byong Kwan Son, Jong Weon Choi, Soo Hwan Pai
Clin Exp Pediatr. 1997;40(10):1386-1393.   Published online October 15, 1997
Purpose : This study was designed to evaluate the incidence of complication in severely obese children and to determine whether the difference of Lp(a) between severely obese children and normal control group exists. Methods : Body weight, height and obesity index were measured in 5885(M:F= 3089:2796) elementary school children. Eight eight(M:F=63:25) were selected as severely obese children. Of the 88 children, 74 agreed to venous...
A Study of the School-based Adolescent Violence
Young Kwan Park, Dae Hun Pee, Young Kyoo Shin, Sang Hee Park, Young Chang Tockgo
Clin Exp Pediatr. 1997;40(10):1376-1385.   Published online October 15, 1997
Purpose : School-based violence among adolescents is a serious public health problem. Recently, it seems to spread and intensify. We were trying to investigate the information about adolescent' s experience, witness and perception in violence, thus to offer the data for appropriate violence prevention methods on our circumstance. Methods : During July, 1996, 3,794 middle or high school students in the metropolitan area of Korea...
Rapid Socio-environmental Changes and Adolescent Problems in Korea
Duk-Jin Yun
Clin Exp Pediatr. 1997;40(10):1360-1375.   Published online October 15, 1997
Purpose : There were rapid socio-environmental changes in Korea caused by industrializations in last thirty years. Those changes are : first, abrupt changes from the environments with closed Confucian ideas to the liberal democratic society, second, agricultural society changed to industrialized society and families with two or three generations are broken down into nuclear families at each generation, third, the annual personal income was...
Analysis of Urinary Mass Screening for Elemantary, Junior and High School Children Over a 8-year Period in Seoul
Chong Guk Lee, Dong Whan Lee, Sae Won Yang, Sung Ho Cha, Chang Ho Hong, Yong Mook Choi, Hyun Soon Lee, Sung Jae Seo
Clin Exp Pediatr. 1997;40(10):1347-1359.   Published online October 15, 1997
Purpose : The urinary mass screening program for the detection of proteinuria had been performed for a school age population in the city of Seoul since 1981. However, systematic evaluation for this program had never been done. We, therefore, designed a systematic evaluation in corporation with the Seoul School Health Center for students with proteinuria identified in the mass screening to determine the prevalence...
Prediction of Steroid Responsiveness in the Primary Nephrotic Syndrome Using Urinary β2-Microglobulin Level and N-Acetyl-β-D-Glucosaminidase Activity
Kwang In Lee, In Seok Lim, Eung Sang Choi
Clin Exp Pediatr. 1997;40(9):1285-1292.   Published online September 15, 1997
Purpose : Considering that renal biopsy is not routinely indicated in nephrotic syndrome in children and the risk of the procedure, we studied that it is possible to predict steroid responsiveness in nephrotic syndrome and the difference in responsivenss is related with the histopathologic type using urinary β2-microglobulin and N-Acetyl-β-D-Glucosaminidase activity as a safe and noninvasive method. Methods : We measured serum creatinine, albumin, cholesterol...
Indomethacin-induced Changesin Renal Blood Flow and Prostaglandin E Excretion in the Cat
Yoon Suck DSuh, Dae Hun Pee, Jae Young Kim, Yu In Park, Kee Hwan Yoo, Joo Won Lee
Clin Exp Pediatr. 1997;40(9):1275-1284.   Published online September 15, 1997
Immunohistochemical Study of Bcl-2 Oncoprotein Expression in Childhood Non-Hodgkin's Lymphoma
Sung Mee Kim, Jin Hwa Jung, Jeong Ho Lee, Jong Dae Jo, Young Tak Lim, Do Youn Park, Sun Kyeung Lee
Clin Exp Pediatr. 1997;40(9):1265-1274.   Published online September 15, 1997
Purpose : The aim of the present study was to assess the clinicopatholgical significance of Bcl-2 oncoprotein expression in childhood non-Hodgkin' s lymphoma(NHL). Methods : We have assessed 16 cases of childhood NHL during last 6 years from 1990 to 1995. Bcl-2 oncoprotein expression has been semiquantitatively analyzed in paraffin sections from 16 cases of childhood NHL with 39 control cases of adult NHL. The...
Early Results of Radiofrequency Catheter Ablation of Supraventricular Tachycardia in Children
Jae Kon Ko, Young Hwee Kim, Young Hwee Kim, Chang Yee Hong, Jae Joong Kim, You Ho Kim
Clin Exp Pediatr. 1997;40(9):1258-1264.   Published online September 15, 1997
Purpose : Although the data of radiofrequency catheter ablation(RFCA) of supraventricular tachycardia in adults has been accumulated in several centers in Korea, few data are available on its efficacy and safety in pediatric ages. We reviewed the data in young patients who underwent this procedure in a pediatric cardiology center, to evaluate the indications, early results, complications, and short-term follow-up data. Methods : We retrospectively...
Interim Results of Single Stage Operation for Coarctation of Aorta with Large Ventricular Septal Defect in Infancy
Ho Sung Kim, Chung Il Noh, Yong Soo Yun, Jung Yun Choi, Jeong Ryul Lee, Yong Jin Kim, Joon Ryang Roh
Clin Exp Pediatr. 1997;40(9):1250-1257.   Published online September 15, 1997
Purpose : There are controversies in the operative methods of aorta with ventricular septal defect in infancy. Recent results of single stage operation for coarctation of aorta with intracardiac defects were regarded as comparable to staged operation. We evaluated our interim results after single stage operation for coarctation of aorta with large ventricular septal defect in infancy. Methods : Twenty six infants who had received...
A Study on Spirometry Pattern of Normal Children
Hyoung-Shin Lee, Young-Hun Chung
Clin Exp Pediatr. 1997;40(9):1242-1249.   Published online September 15, 1997
Purpose : Pulmonary function test is one of the most important tools in the management of patients with respiratory tract diseases and allergic diseases. In recent years pulmonary function tests have had a wide application in clinical pulmonary diseases. But, there were a few trials of pulmonary function test in normal children. So We performed spirometry-based pulmonary function tests of normal children. Methods : We...
Rapid Identification of Mycoplasma Pneumoniae, Mycobacterium Tuberculosis and Staphylococcus Aureus in Pleural Fluid by PCR
Chang Wan Kim, Byung Moon Ahn, Eun Ryoung Kim, Il Su Kim, Yung Seuk Pak, Sang Chul Sung
Clin Exp Pediatr. 1997;40(9):1232-1241.   Published online September 15, 1997
Purpose : Pleural effusions may develop during the course of bacterial pneumonia. The aim of this study was to evaluate the significance of the polymerase chain reaction(PCR) method for detection of M ycoplasma pneumoniae, M ycobaterium tuberculosis and Staphylococcus aureus from pleural fluid. Methods : Total 12 samples were obtained from pleural fluid; 2 samples from children with Mycoplasma pneumonia, 5 samples from adults with...
Erythropoietin Levels in Premature Infants Following Prolonged Treatment with Theophylline
Kug Hwan Kim, Eun Seok Yang, Sang Kee Park
Clin Exp Pediatr. 1997;40(9):1227-1231.   Published online September 15, 1997
Purpose : Theophylline, an adenosine antagonist commonly used in premature infants to treat apnea, has been shown to decrease erythropoietin levels in adults. We studied the effect of theophylline on serum erythropoietin levels in premature infants with apnea. Methods : Subject were 12 premature infants with apnea who were admitted to the NICU, Chosun University Hospital. The first dose of theophylline was 5mg/kg, given...
Visual Evoked Potentials in Healthy Preterm Infants
Young Kook Kim, Young Hwan Kim, Young Sook Hong
Clin Exp Pediatr. 1997;40(9):1219-1226.   Published online September 15, 1997
Purpose : The visual evoked potentials(VEPs) offer a window both on visual system function and on cerebral or neurologic function. The study was performed to evaluate the maturation of VEP in preterm infants and to present a guide to detect high risk neonates who can develop neurodevelopmental abnormalities. Methods : The VEPs were recorded in response to binocular stimulus with light-emitting diode goggles. VEP recordings...
Cerebral palsy, Periventricular echodensity, Cyst, Intraventricular hemorrhage
Kyeung Ho Park, Sang Hee Kim, Hyung Won Lee, Kil Hyun Kim, Hak Soo Lee, Ji Hye Kim, Young Seok Lee
Clin Exp Pediatr. 1997;40(9):1210-1218.   Published online September 15, 1997
Purpose : Although neonatal intensive care and development of obstetrics play a role in improving survival rate in prematurity, cerebral palsy(CP) is still one of the neurologic sequelae. We tried to find what kinds of risk factors in the patients with abnormal neurosonographic findings who developed CP later. This study was performed to predict early enough who will develop CP later and to treat...
Impact of Perinatal Risk Factors on Mental or Psychomotor Developmental Outcome of Very Low Birth W eight Infants
Eun Kyung Jin, Jong Uk Kim, Do Whan Kil, Oh Kyung Lee
Clin Exp Pediatr. 1997;40(9):1202-1209.   Published online September 15, 1997
Purpose : To determine which perinatal risk factors influence neurodevelopmental outcome, we try to investigate which perinatal risk factors are correlated with Baley mental or psychomotor developmental index using BSID-Ⅱ test(Baley Scales of Infant Development, Ⅱ) in long term follow up of very low birth weight who received neonatal intensive care. Methods : This study was performed on 56 very low birth weight infants with...
Cardiovascular Effects of Growth Hormone Treatment in Idiopathic Short Stature
Hyang Ok Woo, Dong Wook Kim
Clin Exp Pediatr. 1997;40(8):1149-1155.   Published online August 15, 1997
Purpose : An excess of GH causes various problems within the cardiovascular system including cardiac hypertrophy and abnormalities of left ventricle(LV) function. To evaluate the cardiovascular effects due to GH treatment in idiopathic short stature (ISS), we measured the cardiovascular function. Methods : Twenty-two echocardiographic studies were performed in ISS who were admitted from Jan. 1994 through Jul. 1996, and they were divided into two...
The Change of Anti-HBs Titer after Injection of HBIG and HBV in Newborn Delivered from HBsAg Carrier Mothers
Qoae Suk Roh, Jin Young Jung
Clin Exp Pediatr. 1997;40(8):1141-1148.   Published online August 15, 1997
Purpose : We studied prevention effects of vertical transmission of Hepatitis B with follow-up, through the change of Anti-HBs titers during 9 months after injection of Hepatitis B immunoglobulin(HBIG) and Hepatitis B vaccine(HBV) at birth in newborn delivered from Hepatitis antigen carrier mothers. Methods : This study was performed on newborn delivered from HBsAg carrier mothers at Hae Sung Hospital from Feb. 1995 to May...
The Pathophysiology of the Transient Neonatal Tricuspid Regurgitation
Dong-Chul Park, Churl-Young Chung, Seauck-Joong Yoon
Clin Exp Pediatr. 1997;40(8):1131-1140.   Published online August 15, 1997
Purpose : This study was carried out to evaluate the role of the septal leaflet of the tricuspid valve. The hypothesis was that the neonatal tricuspid regurgitation(TR) was related to a transient elevation of right ventricular pressure in the neonatal period, that deviated ventricular septum and pull the anchored septal leaflet of the tricuspid valve. The pulled septal leaflet created the incomplete coaptation between...
The Clinical Study on Conversion Rate of Mantoux Test, Change of Local Lesion and Complication after Multipuncture BCG Vaccination in Neonates
Myung Ho Oh, Kee Hyuck Kim, Jae Gun Sim
Clin Exp Pediatr. 1997;40(8):1120-1130.   Published online August 15, 1997
Purpose : Ugly ulcer and keloid formation of injection site has sometimes been a problem in Korea from the cosmetic point of view in intradermal vaccination. Since 3 or 4 years ago, multipuncture BCG vaccination has been used in Korea, there are no data and information about multipuncture BCG vaccination. We therefore performed this study to evaluate of conversion rate, complication and to make...
Serum Lipids and Fatty Acids According to the Type of Feeding in Children
Kyung Hwan Oh, Jae Ock Park, Chang Hwi Kim, Sang Mann Shin
Clin Exp Pediatr. 1997;40(8):1098-1103.   Published online August 15, 1997
Purpose : Lipids and fatty acids are very important for brain and nervous system in growing children. This study was carried out to compare the composition of serum lipids and fatty acids according to the type of feeding in children. Methods : One hundred and twenty two children aged from 5 month to 24 month who visited Soonchunhyang University Hospital from Mar. 1995 to...
Crying Pattern of Infants by Crying Pattern Questionnaire
Keun Lee
Clin Exp Pediatr. 1997;40(8):1091-1097.   Published online August 15, 1997
Purpose : Studies done in Western societies have described characteristics of infant crying behavior. These include:crying peak in the second month, diurnal rhythm(typified by clustering during evening hours) and crying that is robust to differences in caretaking styles. This survey was undertaken to compare the crying patterns of Korean babies with those of their Western counterparts. Methods : From June 1995 to March 1996, well...
An Epidemic of Aseptic Meningitis in Summer 1996 and Global Analysis and Comparision of It with 1993
Jung Ah Chung, Young Jun Kim, Ha Joo Choi, Woo Kap Chung
Clin Exp Pediatr. 1997;40(8):1081-1090.   Published online August 15, 1997
Purpose : In the Summer 1996, there was an outbreak of aseptic meningitis without sequele. 116 cases who were admitted to our Department during a six month period from May to October, 1996. Therefore, we report epidemic of aseptic meningitis in 1996 and analyze and compare it with a epidemic of aseptic meningitis in 1993. Methods : We studies about clinical manefestation and laboratory finding...
Epidemiologic and Clinical Feature of Acute Lower Respiratory Tract Infections by Respiratory Syncytial Virus and Parainfluenza Virus in Children
Jeoung Jin Lee, Hyeon Seon Park, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Woo Kap Chung, Kyu Man Lee
Clin Exp Pediatr. 1997;40(8):1071-1080.   Published online August 15, 1997
Purpose : This is to analyze epidemic and clinical features of acute respiratory tract infections(ALRTI) by respiratory syncytial virus(RSV) and parainfluenza virus(PIV), which are considered to be the major respiratory pathogens in children. Methods : Nasopharyngeal aspirates were collected from 515 patients with ALRTI hospitalized at Hangang Sacred Heart Hospital between Apr. ’94 and Oct. ’96. Nasopharyngeal aspirates were inoculated to...
Zinc and Copper Concentrations and Their Correlation with Protien in Cerebrospinal Fluid of Children with Neurologic Disorders
Myung Joon Cha, Young Joon Kim, Ha Joo Choi, Woo Kap Chung
Clin Exp Pediatr. 1997;40(8):1062-1070.   Published online August 15, 1997
Purpose : The importance of trace elements in their effect on the physiology and pathology of the central nervous system is well recognized. Changes in the concentrations of these elements in the brain could take place in pathological states. Recently, a greater emphasis has been given to the role of trace elements in the function of the nervous system both in normal and pathological...
Seizure Types and EEG Findings of Juvenile Onset Idiopathic Generalized Epilepsy
Hyunmi Kim, Won Seop Kim, Jong Shin Kim, Kangho Cho, Ki Joong Kim, Yong Seung Hwang
Clin Exp Pediatr. 1997;40(7):991-998.   Published online July 15, 1997
Purpose : Juvenile myoclonic epilepsy, juvenile absence epilepsy, and epilepsy wth generalized tonic clonic seizure(GTCS) on awakening are the three syndromes of idiopathic generalized epilepsy of adolescent onset currently included in the classification of epilepsy syndromes of the International League Against Epilepsy(ILAE). Although they differ in their predominant seizure types, the syndromes share several seizure types. Also, there are no unique electrophysiologic or genetic markers....
Urinary Interleukin-1β Levels in Children with Urinary Tract Infection
Kyung Hyo Kim, Young Mi Hong, Gyoung Hee Kim
Clin Exp Pediatr. 1997;40(7):981-990.   Published online July 15, 1997
Purpose : IL-1β and TNF-α are important mediators of the inflammatory response in serious bacterial infections. The mucosal and systemic IL-1β and TNF-α responses to urinary tract infection are analyzed in children with acute urinary tract infection. Methods : We studied the levels of these two cytokines in the urine and sera of 21 children at diagnosis and after treatment with sandwich ELISA method. Results...

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