Journal of the Korean Pediatric Society 1997;40(8):1131-1140.
Published online August 15, 1997.
The Pathophysiology of the Transient Neonatal Tricuspid Regurgitation
Dong-Chul Park1, Churl-Young Chung1, Seauck-Joong Yoon2
1Department of Pediatrics, InJe University Sanggye Paik H ospital, Seoul, Korea
2Department of Pediatrics, Sohwa Childrens`s Hospital, Seoul, Korea
신생아 일과성 삼첨판 폐쇄 부전증의 병인에 대한 연구
박동철1, 정철영1, 윤석중2
1인제대학교 의과대학 상계 백병원 소아과학교실
2소화아동병원 소아과
: This study was carried out to evaluate the role of the septal leaflet of the tricuspid valve. The hypothesis was that the neonatal tricuspid regurgitation(TR) was related to a transient elevation of right ventricular pressure in the neonatal period, that deviated ventricular septum and pull the anchored septal leaflet of the tricuspid valve. The pulled septal leaflet created the incomplete coaptation between the tricuspid valves and the regurgitation.
: We used cross-sectional echocardiography, Doppler and color Doppler echocardiography to measure the normalized ventricular curvature at end-systole, the angle of the septal leaflet of the tricuspid valve, the type of coaptation of the tricuspid valve, the direction of regurgitation and the peak flow rate of regurgitation in 114 normal newborn babies (87 with TR, 27 without TR).
: The normalized septal curvature ratio(p=.0113), the angle of the septal leaflet(p=.0023) and the corrected diameter of the tricuspid valve annulus(p=.0008) were related statistically to the presence of TR(not in the angle of the anterior septum). But in the TR group, right ventricular pressure (calculated through peak velocity of TR) had no correlation with the above variables except the grade of TR(p=.002).
: One of the pathophysiological aspects of the neonatal TR is mainly related to the septal leaflet of the tricuspid valve, but the exact pathophysiology of neonatal TR may also be combined with other factors.
Key Words: Neonatal tricuspid regurgitation, Septal leaflet of the tricuspid valve

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