Impact of Perinatal Risk Factors on Mental or Psychomotor Developmental Outcome of Very Low Birth W eight Infants |
Eun Kyung Jin, Jong Uk Kim, Do Whan Kil, Oh Kyung Lee |
Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea |
극소 저출생 체중아에서 주산기 위험인자가 지능 및 운동발달에 미치는 영향 |
진은경, 김종욱, 길도환, 이오경 |
전주 예수병원 소아과 |
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Abstract |
Purpose : To determine which perinatal risk factors influence neurodevelopmental
outcome, we try to investigate which perinatal risk factors are correlated with Baley
mental or psychomotor developmental index using BSID-Ⅱ test(Baley Scales of Infant
Development, Ⅱ) in long term follow up of very low birth weight who received neonatal
intensive care.
Methods : This study was performed on 56 very low birth weight infants with corrected
age 24 months who were admitted to the neonatal intensive care unit. We
analyzed correlation between perinatal risk factors and neurodevelopmental outcome
assessed by mental and psychomotor developmental index.
Results : Mean birth weight was 1317.8±168.5g : Small for gestational age was 11
cases and appropriate for gestational age was 45 cases : Mean mental developmental index
was 93.8±10.3 and psychomotor developmental index was 99.9±13.2. Mean developmental
scale did not show any significant difference between perinatal risk factors, such as sex,
ventilator care and its duration, hospitalization days, birth weight, small for gestational
age. Mental or psychomotor developmental score was significantly delayed in the
subgroup with grade Ⅲ intraventricular hemorrhages and periventricular cyst. On cranial
ultrasonogram, sinificantly low mental, psychomotor developmental score was found on
the subgroup with grade Ⅲ intraventricular hemorrhages and periventricular cyst
formation larger than 3mm size(P < 0.01).
Conclusions : These findings suggest that grade Ⅲ intraventricular hemorrhage and
periventricular cyst larger than 3mm size are associated with poor prognostic risk factors
regarding to low neurodevelopmental index score. |
Key Words:
Baley scales of infant development, Very low birth weight infant |
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