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Visual Evoked Potentials in Healthy Preterm Infants

Journal of the Korean Pediatric Society 1997;40(9):1219-1226.
Published online September 15, 1997.
Visual Evoked Potentials in Healthy Preterm Infants
Young Kook Kim, Young Hwan Kim, Young Sook Hong
Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
건강한 미숙아의 시각 유발 전위 검사에 관한 연구
김영국, 김영환, 홍영숙
고려대학교 의과대학 소아과학교실
: The visual evoked potentials(VEPs) offer a window both on visual system function and on cerebral or neurologic function. The study was performed to evaluate the maturation of VEP in preterm infants and to present a guide to detect high risk neonates who can develop neurodevelopmental abnormalities.
: The VEPs were recorded in response to binocular stimulus with light-emitting diode goggles. VEP recordings were analyzed in 37 healthy neonates who were followed longer than 6 months and neurodevelopmentally normal.
: 1) The peak latencies of N1 were 158.4±42.4(msec), 159.4±40.6, 80.2±20.6, 52.4±12.0 from 34 to 42 weeks, respectively. 2) The peak latencies of P1 were 227.7±34.4(msec), 187.0±35.4, 124.4±30.2, 148.3±44.9 from 34 to 42 weeks, respectively. 3) The peak latencies of N2 were 315.4±49.9(msec), 228.6±44.2, 205.5±69.3, 194.4±89.9 from 34 to 42 weeks, respectively. 4) The peak latencies of P2 were 403.1±87.0(msec), 275.4±61.5, 232.5±58.7, 255.1±125.1 from 34 to 42 weeks, respectively. 5) The mean amplitude of N1-P1, P1-N2, N2-P2 were 5.3±6.8(μV), 5.3±5.5, 5.5± 4.1 respectively. The peak latencies were inversely related to post-conceptional age(P < 0.05).
: The peak latencies of each wave were decreased according to the post-conceptional age and these data reflect maturational changes in brain function.
Key Words: Visual evoked potential(VEP), Preterm infants

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