Visual Evoked Potentials in Healthy Preterm Infants |
Young Kook Kim, Young Hwan Kim, Young Sook Hong |
Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea |
건강한 미숙아의 시각 유발 전위 검사에 관한 연구 |
김영국, 김영환, 홍영숙 |
고려대학교 의과대학 소아과학교실 |
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Abstract |
Purpose : The visual evoked potentials(VEPs) offer a window both on visual system
function and on cerebral or neurologic function. The study was performed to evaluate
the maturation of VEP in preterm infants and to present a guide to detect high risk
neonates who can develop neurodevelopmental abnormalities.
Methods : The VEPs were recorded in response to binocular stimulus with
light-emitting diode goggles. VEP recordings were analyzed in 37 healthy neonates who
were followed longer than 6 months and neurodevelopmentally normal.
Results :
1) The peak latencies of N1 were 158.4±42.4(msec), 159.4±40.6, 80.2±20.6, 52.4±12.0
from 34 to 42 weeks, respectively.
2) The peak latencies of P1 were 227.7±34.4(msec), 187.0±35.4, 124.4±30.2, 148.3±44.9
from 34 to 42 weeks, respectively.
3) The peak latencies of N2 were 315.4±49.9(msec), 228.6±44.2, 205.5±69.3, 194.4±89.9
from 34 to 42 weeks, respectively.
4) The peak latencies of P2 were 403.1±87.0(msec), 275.4±61.5, 232.5±58.7, 255.1±125.1
from 34 to 42 weeks, respectively.
5) The mean amplitude of N1-P1, P1-N2, N2-P2 were 5.3±6.8(μV), 5.3±5.5, 5.5± 4.1
respectively.
The peak latencies were inversely related to post-conceptional age(P < 0.05).
Conclusions : The peak latencies of each wave were decreased according to the
post-conceptional age and these data reflect maturational changes in brain function. |
Key Words:
Visual evoked potential(VEP), Preterm infants |
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