- Review Article
- General Pediatrics
- Protecting our future: environmental hazards and children’s health in the face of environmental threats: a comprehensive overview
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Jungha Lee, Hyo-Bin Kim, Hun-Jong Jung, Myunghee Chung, So Eun Park, Kon-Hee Lee, Won Seop Kim, Jin-Hwa Moon, Jung Won Lee, Jae Won Shim, Sang Soo Lee, Yunkoo Kang, Young Yoo; The Environmental Health Committee of the Korean Pediatric Society
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Clin Exp Pediatr. 2024;67(11):589-598. Published online October 31, 2024
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· Exposure to air pollutants cause allergic and respiratory diseases as well as chronic kidney disease.
· Adequate physical activity and proper nutrition are essential for children to maintain good health.
· We must educate people about the harmful effects of noise, blue light, heavy metals and smoke.
· Government and society must actively decrease environ-mental hazards. |
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- Case Report
- Allergy
- Breast abscess caused by Staphylococcus aureus in 2 adolescent girls with atopic dermatitis
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Sung Man Park, Won Sik Choi, YoonSun Yoon, Gee Hae Jung, Chang Kyu Lee, So Hyun Ahn, Yoon Wonsuck, Young Yoo
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Clin Exp Pediatr. 2018;61(6):200-204. Published online June 25, 2018
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Atopic dermatitis (AD) is a chronic inflammatory skin disease in children. Patients with AD experience a high rate of colonization of the skin surface by Staphylococcus aureus. Because of a skin barrier defect, there is a potential risk of staphylococcal invasive infection in patients with AD. Here, we present 2 cases of breast abscess caused by S. aureus in 2... |
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- Pulmonology
- Congenital miliary tuberculosis in an 18-day-old boy
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Jue Seong Lee, Chang Hoon Lim, Eunji Kim, Hyunwook Lim, Yoon Lee, Ji Tae Choung, Young Yoo
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Clin Exp Pediatr. 2016;59(Suppl 1):S64-S67. Published online November 30, 2016
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Congenital tuberculosis (TB) is a rare disease that is associated with high mortality. Mycobacterium tuberculosis, the causative agent, may be transmitted from the infected mother to the fetus by the transplacental route or by aspiration of infected amniotic fluid. Clinical symptoms and signs are not specific. Miliary patterns are the most common findings in the chest X-rays of many infants... |
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- Original Article
- Predictive value of C-reactive protein in response to macrolides in children with macrolide-resistant Mycoplasma pneumoniae pneumonia
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Young Ho Seo, Jang Su Kim, Sung Chul Seo, Won Hee Seo, Young Yoo, Dae Jin Song, Ji Tae Choung
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Clin Exp Pediatr. 2014;57(4):186-192. Published online April 30, 2014
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Purpose The prevalence of macrolide-resistant Mycoplasma pneumoniae (MRMP) has increased worldwide. The aim of this study was to estimate the proportion of MRMP in a tertiary hospital in Korea, and to find potential laboratory markers that could be used to predict the efficacy of macrolides in children with MRMP pneumonia. MethodsA total of 95 patients with M. pneumoniae pneumonia were enrolled in... |
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- Review Article
- Phenotypes and endotypes of severe asthma in children
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Young Yoo
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Clin Exp Pediatr. 2013;56(5):191-195. Published online May 28, 2013
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Severe childhood asthma is a complicated and heterogeneous disorder with distinct phenotypes. Children with severe asthma have more persistent symptoms despite receiving treatment, more atopy, greater airway obstruction, and more air trapping than those with mild-to-moderate asthma. They also have higher morbidity and substantial airflow limitations that persist throughout adulthood. Identification of the phenotype clusters and endotypes of severe asthma... |
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- Case Report
- Idiopathic acute eosinophilic pneumonia in a 14-month-old girl
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Ha Neul Park, Bo Hyun Chung, Jung Eun Pyun, Kwang Chul Lee, Ji Tae Choung, Choon Hak Lim, Young Yoo
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Clin Exp Pediatr. 2013;56(1):37-41. Published online January 29, 2013
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Idiopathic acute eosinophilic pneumonia (IAEP), characterized by acute febrile respiratory failure associated with diffuse radiographic infiltrates and pulmonary eosinophilia, is rarely reported in children. Diagnosis is based on an association of characteristic features including acute respiratory failure with fever, bilateral infiltrates on the chest X-ray, severe hypoxemia and bronchoalveolar lavage fluid >25% eosinophils or a predominant eosinophilic infiltrate in lung... |
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- Original Article
- CD4+/CD8+ T lymphocytes imbalance in children with severe 2009 pandemic influenza A (H1N1) pneumonia
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Ji Eun Kim, Siegfried Bauer, Kyong Suk La, Kee Hyoung Lee, Ji Tae Choung, Kyoung Ho Roh, Chang Kyu Lee, Young Yoo
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Clin Exp Pediatr. 2011;54(5):207-211. Published online May 31, 2011
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Purpose This study was conducted to investigate the immune responses of children with moderate and severe novel influenza A virus (H1N1) pneumonia, and to compare their clinical and immunological findings with those of control subjects. MethodsThirty-two admitted patients with H1N1 pneumonia were enrolled in the study. The clinical profiles, humoral and cell-mediated immune responses of the 16 H1N1 pneumonia patients who were... |
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- Case Report
- Isolated pulmonary cryptococcosis in an immunocompetent boy
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Siegfried Bauer, Ji Eun Kim, Kyong Suk La, Young Yoo, Kee Hyoung Lee, Sang Hee Park, Ji Tae Choung, Chul Whan Kim
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Clin Exp Pediatr. 2010;53(11):971-974. Published online November 30, 2010
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Pulmonary cryptococcosis is rare in immunocompetent subjects. Here, we present the case of a 16-year-old boy who was referred to our pediatric department for the management of multiple consolidations detected on chest radiography, which was routinely performed when the patient was being evaluated for an ankle fracture. Fine needle aspiration biopsy was performed, and the definitive diagnosis was established as... |
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- Original Article
- Effects of inhaled corticosteroids on bone mineral density and bone metabolism in children with asthma
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Ic Sun Choi, Jung Hye Byeon, Seung Min Lee, Kyong Suk La, Yeon Joung Oh, Young Yoo, Kee Hyoung Lee, Ji Tae Choung
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Clin Exp Pediatr. 2009;52(7):811-817. Published online July 15, 2009
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Purpose : Inhaled corticosteroids (ICS) are used as first-line agents for the treatment of persistent asthma; however, their use is accompanied by apprehension of potential systemic adverse effects. This study aimed to assess the effects of ICS on bone mineral density (BMD) and bone metabolism in children with asthma.
Methods : From February 2008 to September 2008, 26 asthmatic children treated... |
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- Increased vascular endothelial growth factor in children with
acute Mycoplasma pneumoniae pneumonia and wheezing
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Young Seo, Byung Keun Yu, Yeon Joung Oh, Yoon Lee, Young Yoo, Ji Tae Choung, Young Yull Koh
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Clin Exp Pediatr. 2008;51(5):487-491. Published online May 15, 2008
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Purpose : Although Mycoplasma pneumoniae (M. pneumoniae) infection can cause wheezing in non-asthmatic children, the mechanisms of this symptom remain unclear. Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis and vascular permeability, and is also known to be elevated in cases of chronic pulmonary disease such as asthma. We hypothesized that VEGF may increase in children with... |
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- Effects of an intensive asthma education program on
asthmatic children and their caregivers
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Kang Jin Seo, Gun Ha Kim, Byung Keun Yu, Yun Ku Yeo, Jong Hoon Kim, Eu Ddeum Shim, Mi Ri Yoon, Young Yoo, Ji Tae Choung
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Clin Exp Pediatr. 2008;51(2):188-203. Published online February 15, 2008
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Purpose : Asthma is one of the most common chronic childhood disease. Education of asthmatic children and their families about asthma and its management may improve disease control, reduce symptoms, and improve school performance. The aim of the study was to evaluate the effects of an intensive asthma education program in asthmatic children and their families on outcome measure... |
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- Clinical application of D-dimer in Kawasaki Disease
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Jae Joon Han, Hong Ki Ko, Young Yoo, JungHwa Lee, Kwang Chul Lee, Chang Sung Son, Joo Won Lee
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Clin Exp Pediatr. 2007;50(2):205-208. Published online February 15, 2007
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Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
Purpose : Vascular endothelial cell damage and alteration of a fibrinolytic system was suggested to play a role in the development of coronary artery abnormalities in Kawasaki disease (KD). D-dimer is one of the markers of endothelial damage and fibrinolysis. We evaluated the clinical usefulness of D- dimer to differentiate KD... |
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- Case Report
- Three cases of pulmonary and/or intestinal tuberculosis
in adolescents
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Jung Hye Byeon, Yoon Lee, Jin Chul Lee, Young Yoo, Kee Hyoung Lee, Kwang Chul Lee, Ji Tae Choung, Soo Youn Ham, Chul Whan Kim
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Clin Exp Pediatr. 2007;50(11):1134-1138. Published online November 15, 2007
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Since the tuberculosis (TB) in adolescents has unique clinical characteristics, special attention should be paid to this age group. Adolescents are more susceptible to developing TB disease and more likely to have cavitary pulmonary disease. Also, adolescent patients with TB more frequently present with extrapulmonary disease. We report three adolescents with active pulmonary and/or intestinal TB: one had pulmonary and... |
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- Original Article
- Health and risk taking behaviors of freshmen in college
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Hong Ki Ko, Jae Joon Han, Yoon Lee, Young Yoo, Kee Hyoung Lee, Ji Tae Choung, Sang Hee Park
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Clin Exp Pediatr. 2006;49(10):1042-1049. Published online October 15, 2006
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Purpose : This study was conducted to survey the preliminary data on risk behaviors and to identify the factors that prevent risk-behaviors in late adolescence.
Methods : Freshmen(n=1,297) beginning the first semester in Korea University, Seoul, Korea completed self-administered risk behavior questionnaires, comprising 5 domains : demographics, smoking, drinking, drug abuse and sexual behavior.
Results : The rate of smoking experience was... |
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- Case Report
- A case of Kikuchi's disease with skin involvement
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Ji Min Jang, Chul Hee Woo, Jung Woo Choi, Dae Jin Song, Young Yoo, Kwang Chul Lee, Chang Sung Son
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Clin Exp Pediatr. 2006;49(1):103-106. Published online January 15, 2006
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Histiocytic necrotizing lymphadenitis, which is also commonly referred to as Kikuchi's disease (KD), is a self-limiting disease of unknown etiology. It affects individuals of all ages, although it is usually seen in young women. However, only a few descriptions of this disease are available in the pediatric literature. KD is clinically characterized by cervical lymphadenopathy, high fever, myalgia, neutropenia and,... |
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- Original Article
- A Study of Antibody Conversion Rate During a Mycoplasma pneumoniae Epidemic Period(the Second Half of 2003)
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Do Kyun Kim, Young Yoo, Jinho Yu, Young Yull Koh
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Clin Exp Pediatr. 2005;48(5):500-505. Published online May 15, 2005
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Purpose : This study was designed to estimate the prevalence of Mycoplasma pneumoniae infection during an epidemic period by means of examining the antibody conversion rate and to investigate the association of the antibody conversion with age, initial antibody titer, and atopy.
Methods : We chose 191 children whose antibody titer to M. pneumoniae was negative, 1 : 40, or... |
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- Bronchial Hyperresponsiveness and Atopy in 6-8 Year Old Children According to the History of Wheezing in Early Childhood
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Jinho Yu, Young Yoo, Hee Kang, Young Yull Koh
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Clin Exp Pediatr. 2004;47(8):873-878. Published online August 15, 2004
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Purpose : It is becoming generally recognized that wheezing in early childhood is a heterogeneous condition and does not always develop into asthma. This study aimed to determine characteristics of wheezing phenotypes in early childhood and investigate their relation to asthma.
Methods : Two hundreds and sixty 6-8 year old children with past or present wheezeing were enrolled, and their history... |
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- The Relationship between House Dust Mite Sensitization and
Month Birth Distribution in Children with Respiratory Allergy
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Eun Kyeong Kang, Kyu Min Na, Hee Kang, Young Yoo, Young Yull Koh
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Clin Exp Pediatr. 2003;46(4):370-375. Published online April 15, 2003
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Purpose : It has been suggested that the exposure to aeroallergens during early infancy after birth is important in the subsequent development of sensitization and allergic diseases. In Korea, the level of house dust mites as one of the important aeroallergens is known to be the highest in autumn. The aim of this study was to test whether the distribution... |
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- The Characteristics of the 2000-2001 Measles Epidemic in the Seoul Metropolitan Area
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Dae Hun Pee, So Hoon Byun, Kyung Burm Kim, Young Yoo, Kee Hyoung Lee, Young Kyoo Shin
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Clin Exp Pediatr. 2002;45(10):1219-1226. Published online October 15, 2002
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Purpose : To assess the clinical characteristics of the 2000-2001 measles outbreak in the Seoul
metropolitan area, Korea, the clinical data of measles inpatients were analyzed.
Methods : Three hundred and five children diagnosed with measles by clinical manifestation from
July, 2000 to February, 2001, in Seoul, Ilsan and Ansan City were grouped according to their age
and investigated for clinical manifestations, vaccination history... |
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- Postnatal Changes in Left Ventricular Performance in Early Neonatal Life
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Sung Wook Yang, Chan Wook Woo, Jee Youn Lim, Jung Hwa Lee, Joo Won Lee, Chang Sung Son, Young Chang Tockgo, Young Yoo
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Clin Exp Pediatr. 2000;43(9):1168-1173. Published online September 15, 2000
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Purpose : This study was undertaken to investigate changes in cardiac performance in early neonatal life by observing the changes of left ventricular(LV) function and volume according to the size of ductus arteriosus.
Methods : The study group consisted of 21 full-term Cesarean section neonates who were admitted to the nursery of Korea University Hospital. We serially investigated the... |
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- Developmental mRNA Expression of Cellular Retinoic Acid Binding Protein I and Ⅱ in Rat
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Young Yoo, Hyung Suk Kim, Chang Sung Son, Young Chang Tockgo, Young Hyuk Jeon
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Clin Exp Pediatr. 1998;41(2):154-162. Published online February 15, 1998
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Purpose : Retinoic acid(RA) is well known as a potent teratogenic agent in both deficiency and excess. Cellular retinoic acid binding proteins(CRABPs) are involved in RA. We carried this study in order to determine the possible relations of CRABPs with RA-induced teratogenesis through observation of the expression patterns of CRABP Ⅰand Ⅱ in developing rats.
Methods : 35S-labeled RNA probes were... |
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- Plasma Fibronectin Concentration in the Neonate
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Young Yoo, Kwang Chul Lee, Young Chang Tockgo
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Clin Exp Pediatr. 1996;39(3):319-325. Published online March 15, 1996
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Purpose : Plasma fibronectin is thought to have important role in the inflammatory response and host defense. We performed this study to evaluate concentration in the full-term, healthy preterm, asphyxia and respiratory distress syndrome and how that correlated with gestational age and birth weight.
Methods : We evaluate 51 neonates who were delivered at Korea University Hospital from Jan. 1992 to... |
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- Clinical Evaluation of Reactive Thrombocytosis in Childhood
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Yoon Suck Suh, Young Yoo, Kwang Chul Lee, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 1992;35(5):607-613. Published online May 15, 1992
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The platelet coiunt has not been part of routine hematologic profiles until recently, when the newer electronic blood cell counters began to include platelet count with all other blood cell counts. With the widespread use of newer generation electronic blood cell counters, elevated platelets coiunts are being encountered more ofter in pediatric practice.
We reviewed all cases of marked thrombocytosis to... |
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- Conjoined Thoracopagus Twins.
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Min Young Lee, Young Yoo, Ji Tae Choung, Joo Won Lee, Young Chang Tockgo, Yang Seouk Chae
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Clin Exp Pediatr. 1990;33(5):671-674. Published online May 31, 1990
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Conjoined twins are very rare congenital malformation in which twins have varying degree of
anatomical union. The conjoined twins seems preferable to such as craniopagus, thoracopagus,
ischiopagus and pyopagus. Because of their associated anomalies, particularly of cardiovascular
system, and difficulties in delivery, they usually survive only short postnatal period. Successful
surgical separation and long term survival would have been achieved in a small numbers... |
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