- Original Article
- Diencephalic syndrome: a frequently neglected cause of failure to thrive in infants
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Ahlee Kim, Jin Soo Moon, Hye Ran Yang, Ju Young Chang, Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2015;58(1):28-32. Published online January 31, 2015
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Purpose Diencephalic syndrome is an uncommon cause of failure to thrive in early childhood that is associated with central nervous system neoplasms in the hypothalamic-optic chiasmatic region. It is characterized by complex signs and symptoms related to hypothalamic dysfunction; such nonspecific clinical features may delay diagnosis of the brain tumor. In this study, we analyzed a series of cases in order... |
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- Usefulness of early endoscopy for predicting the development of stricture after corrosive esophagitis in children
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Ji Yong Park, Jee Youn Shin, Hye Ran Yang, Jae Sung Ko, Woo Sun Kim, Jeong Kee Seo
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Clin Exp Pediatr. 2009;52(4):446-452. Published online April 15, 2009
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Purpose : This study was performed to demonstrate the usefulness of early endoscopy for predicting the development of stricture following corrosive ingestion in children.
Methods : We conducted a retrospective study on 34 children who were brought to Seoul National University Childrens Hospital and Seoul National University Bundang Hospital for corrosive ingestion from 1989 to 2007.
Results : The corrosive burns were... |
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- Case Report
- Autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome in a 10-year-old girl with ulcerative colitis
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Jeana Hong, Mi Kyoung Song, Jae Sung Ko, Gyeong Hoon Kang, Woo Sun Kim, Jeong Kee Seo
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Clin Exp Pediatr. 2009;52(4):504-507. Published online April 15, 2009
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Autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and primary biliary cirrhosis (PBC) are chronic autoimmune liver diseases. Overlap syndrome is defined as a condition in which the clinical, biochemical, and histological features of these autoimmune diseases are overlapped. Thus, it is difficult to appreciate overlap syndrome as an actual diagnostic entity. Only a few cases of the overlap syndrome of... |
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- A case of simultaneously identified glycogen storage disease and
mucopolysaccharidosis
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Ju Young Lee, Jeong Ok Shim, Hye Ran Yang, Ju Young Chang, Choong Ho Shin, Jae Sung Ko, Jeong Kee Seo, Woo Sun Kim, Gyeong Hoon Kang, Jeong Han Song, Jong Won Kim
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Clin Exp Pediatr. 2008;51(6):650-654. Published online June 15, 2008
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Glycogen storage disease (GSD) and mucopolysaccharidosis (MPS) are both independently inherited disorders. GSD is a member of a group of genetic disorders involving enzymes responsible for the synthesis and degradation of glycogen. GSD leads to abnormal tissue concentrations of glycogen, primarily in the liver, muscle, or both. MPS is a member of a group of inherited lysosomal storage diseases, which... |
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- A case of Menkes disease with unusual hepatomegaly
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Go Un Jeong, Anna Cho, Hee Hwang, Yong Seung Hwang, Ki Joong Kim, Jong Hee Chae, Jeong Kee Seo
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Clin Exp Pediatr. 2008;51(5):538-541. Published online May 15, 2008
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Menkes disease is an X-linked recessive copper transport disorder characterized by neurological deterioration, connective- tissue damage, and abnormal hair growth. It is caused by the mutation of the ATP7A gene. This report describes a four- month-old boy with neurological symptoms typical of Menkes disease plus unusual liver involvement. He developed seizures at three months of age and exhibited hypotonia, cephalhematoma,... |
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- Review Article
- The etiologies of neonatal cholestasis
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Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2007;50(9):835-840. Published online September 15, 2007
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Any infant noted to be jaundiced at 2 weeks of age should be evaluated for cholestasis with measurement of total and direct serum bilirubin. With the insight into the clinical phenotype and the genotypephenotype correlations, it is now possible to evaluate more precisely the neonate who presents with conjugated hyperbilirubinemia. Testing should be performed for the specific treatable causes of... |
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- Original Article
- Intravenous immunoglobulin for severe gastrointestinal manifestation of Henoch-Sch nlein purpura refractory to corticosteroid therapy
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Hye Ran Yang, Won Jung Choi, Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(7):784-789. Published online July 15, 2006
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Purpose : Henoch-Schönlein purpura(HSP) is a systemic vasculitis involving small vessels of skin, gastrointestinal(GI) tract and kidney. Digestive involvement of HSP can be serious with massive GI bleeding, perforation, and intussusception. However, some patients do not respond to conventional corticosteroid therapy. In this study, we investigated the efficacy of intravenous immunoglobulin (IVIG) for serious digestive manifestations not responding to steroid.
Methods... |
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- Jagged1 mutation analysis in Alagille syndrome patients
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Jae Sung Ko, Hye Ran Yang, Kyung Mo Kim, Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(5):519-522. Published online May 15, 2006
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Purpose : Alagille syndrome is an autosomal dominant disorder with developmental abnormalities affecting the liver, heart, eyes, vertebrae, and craniofacial region. The Jagged1(JAG1) gene, which encodes a ligand of Notch, has been found mutated in Alagille syndrome. The aim of the study was to investigate the mutation analysis of JAG1 gene in Korean patients with Alagille syndrome.
Methods : Genomic DNA... |
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- Helicobacter pylori reinfection rate by a 13C-urea breath test and endoscopic biopsy tests in Korean children
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Jeong Ok Shim, Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(3):268-272. Published online March 15, 2006
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Purpose : The reinfection rate of H. pylori reported before 13C-urea breath test(13C-UBT) era was higher than that of the post 13C-UBT era. Children are usually reluctant to receive invasive endoscopic evaluation for the reinfection of H. pylori, particularly when they are asymptomatic. The aim of the study is to discover the reinfection rate by different diagnostic tests, and to... |
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- Review Article
- Helicobacter pylori infection and abdominal pain in children
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Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(2):136-143. Published online February 15, 2006
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The relationship between H. pylori(Hp) infection and recurrent abdominal pain(RAP) in children is not clear. Current data in the literature regarding a causal relationship between Hp infection and childhood RAP are conflicting. However, meta-analysis and most of the recently published studies have not supported an association between Hp infection and an increased prevalence of abdominal pain. Most published studies have... |
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- Case Report
- Gastric neurofibroma in von Recklinghausen disease : a cause of upper gastrointestinal bleeding
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Bo Sang Kwon, Jeong Ok Shim, Jeong Kee Seo, Hye Ran Yang, Jae Sung Ko, Seong Eun Jung, Woo Sun Kim, Gyeong Hoon Kang
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Clin Exp Pediatr. 2006;49(2):203-207. Published online February 15, 2006
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Neurofibromatosis type 1 (von Recklinghausen disease, NF1) involves the central and peripheral nervous systems as well as the skin, bone, endocrine, gastrointestinal and vascular systems. The gastrointestinal neurofibroma associated with NF1 has been infrequently reported. We report our experience with a 15-year-old boy who had a gastric plexiform neurofibroma with upper gastrointestinal bleeding and underwent a tumorectomy because of massive... |
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- Original Article
- A case of hereditary pancreatitis with a N29I mutation in the cationic trypsinogen gene
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Jee Youn Shin, You Jeong Kim, Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(10):1067-1072. Published online October 15, 2006
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Purpose : The purpose of this study was to examine the clinical courses and long-term outcomes of children with Allagille syndrome in Korea, and to evaluate the prognostic potentials of identified variables.
Methods : We reviewed the clinical manifestations and outcomes of 30 children with Alagille syndrome, investigated from 1984 to 2006 until the end of this study (defined as death... |
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- Case Report
- A case of post-operative chylous ascites after a splenorenal shunt operation in a child with congenital hepatic fibrosis
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Jong Hyung Yoon, Hye Ran Yang, Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(10):1106-1110. Published online October 15, 2006
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Chylous ascites is a rare condition caused by various diseases and conditions that interfere with the abdominal or retroperitoneal lymphatics, and uncommonly it can manifest as a post-operative complication after abdominal, retroperitoneal or mediastinal surgery. Chylous ascites can be diagnosed by a high triglyceride content in ascites. The authors experienced a 5-year-old girl with congenital hepatic fibrosis who presented with... |
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- A case of hereditary pancreatitis with a N29I mutation in the cationic trypsinogen gene
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Jee Youn Shin, Dae Sung Oh, Jeong Min Rheu, Jeong Ok Shim, Ji Sook Park, Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(10):1111-1115. Published online October 15, 2006
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Hereditary pancreatitis is an autosomal dominant disease characterized by recurrent episodes of pancreatitis, often beginning in childhood, with a positive family history involving at least two other affected family members with no known other precipitating factors. Most forms of hereditary pancreatitis are caused by one of two common mutations, i.e., R122H in exon 3 and N29I in exon 2 of... |
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- Development of Crohn disease in patients with myelodysplastic syndrome : report of two children
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Jeong Ok Shim, Jeong Kee Seo, Hye Ran Yang, Jae Sung Ko, Hee Young Shin, Hyo Seop Ahn, Woo Sun Kim, Gyeong Hoon Kang
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Clin Exp Pediatr. 2006;49(1):107-111. Published online January 15, 2006
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Crohn disease (CD) is rare, but the incidence of CD has been increasing over the past ten years. We found two cases of CD, associated with myelodysplastic syndrome (MDS), for the first time in children. In the first patient, MDS was diagnosed at three years of age and CD developed later at eight years of age. The patient presented with... |
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- Original Article
- Clinical Findings of Genotypes in Korean Patients with Glycogen Storage Disease Type Ia
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Jae Sung Ko, Hye Ran Yang, Jong Won Kim, Jeong Kee Seo
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Clin Exp Pediatr. 2005;48(8):877-880. Published online August 15, 2005
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Purpose : Glycogen storage disease type Ia(GSD Ia) is an autosomal recessive disorder caused by the deficiency of glucose-6-phosphatase(G6Pase). The aim of the study was to investigate the spectrum of G6Pase gene mutations and relationship between genotype and clinical findings in Korean patients with GSD Ia.
Methods : Genomic DNA was extracted from peripheral leukocytes of 20 patients with GSD... |
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- Correlation of Body Mass Index, Body Fat Distribution, Aminotranferases and Computed Tomography in
Obese Children with Fatty Liver
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So Eun Park, Hye Ran Yang, Ju Young Chang, Jae Sung Ko, Jeong Kee Seo, Whal Lee, Woo Sun Kim
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Clin Exp Pediatr. 2005;48(3):276-283. Published online March 15, 2005
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Purpose : Visceral fat accumulation plays a major role in metabolic complications of obesity. It is known that nonalcoholic fatty liver in obese adults is associated with visceral fat accumulation. Body mass index(BMI) is used as the index of obesity in children. The aim of this study is to evaluate the correlation of BMI and visceral adipose tissue(VAT), and the... |
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- Henoch-Scholein Purpura Presenting with Acute Abdominal Pain Preceding Skin Rash : Review of 23 Cases
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Ju Young Chang, Yong Joo Kim, Kyo Sun Kim, Hee-Ju Kim, Jeong Kee Seo
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Clin Exp Pediatr. 2003;46(6):576-584. Published online June 15, 2003
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Purpose : For the early diagnosis of Henoch-Schonlein purpura(HSP) presenting with acute abdominal pain preceding skin rash.
Methods : The clinical, endoscopic and radiological records of 23 cases of HSP, presenting with gastrointestinal symptoms preceding skin rash were reviewed.
Results : The intervals from the onset of abdominal pain to the development of the skin rash were one day to 30 days(median... |
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- Therapeutic Efficacy of Cefotaxime as an Empirical
Antibiotic on Ascending Cholangitis after
Kasai Operation for Biliary Atresia
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Dong Ho Kim, Byong Sop Lee, Yun Kyung Kim, Jae Sung Ko, Hoan Jong Lee, Jeong Kee Seo
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Clin Exp Pediatr. 2002;45(4):474-481. Published online April 15, 2002
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Purpose : Ascending cholangitis is the most common complication after Kasai operations. The aim of this study is to evaluate the therapeutic efficacy of cefotaxime as an empirical antibiotic on ascending cholangitis after Kasai operations.
Methods : Thirty-nine episodes of cholangitis in twenty-nine children who underwent Kasai operations at Seoul National University Children's Hospital from January 1991 to December 2000 were... |
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- Case Report
- A Case of Hereditary Fructose Intolerance
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Eun Kyeong Kang, Hye Ran Yang, Jeong Kee Seo, Sun Hoan Bai, Joo Young Jeong, Jae Sung Ko, Il Soo Ha, Jeong Han Song, Kyeong Ae Wi, Yoon Sook Shin
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Clin Exp Pediatr. 2002;45(1):120-124. Published online January 15, 2002
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Hereditary fructose intolerance(HFI) is an autosomal recessive disease caused by catalytic deficiency
of aldolase B in which affected homozygotes develop hypoglycemia and abdominal symptoms
after taking foods containing fructose. Chronic exposure to fructose may lead to progressive
hepatic injury, renal injury, growth retardation, and ultimately to liver and kidney failure. Herein,
we report a case of HFI with presentation of episodic vomiting, diarrhea, cold... |
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- Original Article
- Long-term Clinical Follow-up of Korean Children with Wilson Disease; Twenty Years` Experience
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Jin Soo Moon, Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2001;44(2):127-138. Published online February 15, 2001
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Purpose : To investigate the clinical features of long-term follow-up, and the treatment responses in Korean children with Wilson disease(WD).
Methods : The clinical data from ninety-two children with WD, diagnosed at Seoul National University Hospital from 1976 to 1999, were reviewed. Mean duration of follow-up was 5¡¾4.5 years. We analysed the patient's records based on the clinical manifestations, laboratory findings,... |
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- A Study on the Disease Course and Prognosis of
Cyclic Vomiting Syndrome
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Hye Ran Yang, Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2001;44(10):1141-1156. Published online October 15, 2001
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Purpose : To describe clinical features of cyclic vomiting syndrome(CVS), managements during episodes, prophylactic drugs as long term therapy and to investigate the disease course and prognostic factors of CVS.
Methods : Thirty two children who fulfilled the diagnostic criteria of CVS and who presented to Seoul National University Children's Hospital from March 1989 to December 2000, were included. Data were... |
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- Congenital Chloride Diarrhea in 5 Korean Infants
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Dong Hun Rhie, Sun Hwan Bae, Ji Eun Choi, Bo Young Yun, Dong Woo Son, Choong Ho Shin, Kyung Hee Park, Jae Sung Ko, Jeong Kee Seo
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Clin Exp Pediatr. 2000;43(11):1465-1472. Published online November 15, 2000
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Purpose : Congenital chloride diarrhea(CLD) is an autosomal recessive disease characterized by life-long watery diarrhea of prenatal onset with high fecal Cl－ concentration. Recent studies have revealed that the protein product of the down-regulated in adenoma(DRA) gene is an intestinal anion transporter molecule and causes CLD when mutated. We investigated the clinical characteristics of CLD in Korean infants in order... |
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- Renal Problems in Wilson Disease
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Il Soo Ha, Jun Ho Lee, Yeon Ho Choe, Hae Il Cheong, Sei Won Yang, Young Yull Koh, Jeong Kee Seo, Yong Choi
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Clin Exp Pediatr. 1999;42(6):817-824. Published online June 15, 1999
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Purpose : Wilson disease is a hereditary metabolic disorder characterized by an accumulation of copper in tissues which sometimes results in renal problems. This study was performed to evaluate the prevalences of the renal problems in Wilson disease and related risk factors.
Methods : In 31 patients with Wilson disease, we looked for renal problems by history taking, physical examination... |
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- Clinical Profiles and Anatomic Classification of Intestinal Malrotation
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Jung A Kim, Jae Seong Ko, Jeong Kee Seo, Kwi Won Park, Woo Sun Kim, In One Kim
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Clin Exp Pediatr. 1999;42(4):526-534. Published online April 15, 1999
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Purpose : Intestinal malrotation is a developmental anomaly and may be complicated by volvulus and intestinal necrosis. We performed anatomic classification and compared clinical profiles to understand their relationship.
Methods : Twenty-eight children were diagnosed as intestinal malrotation at Seoul National University Children's Hospital between Jan. 1980 to Dec. 1995. The patients were classified into 4 groups by age at... |
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- Longterm Follow-up of Autosomal Recessive Polycystic Kidney Disease
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June Huh, Il Soo Ha, Hae Il Cheong, Jeong Kee Seo, Yong Choi
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Clin Exp Pediatr. 1998;41(12):1693-1699. Published online December 15, 1998
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Purpose : This study was aimed to assess the clinical manifestations and courses of autosomal recessive polycystic kidney disease(ARPKD).
Methods : The medical records of 10 children diagnosed as infantile or juvenile ARPKD at Seoul National University Children's Hospital between January, 1984 and December, 1996, were reviewed, retrospectively.
Results : The average age at diagnosis was 3 8/12 years(4months-7 3/12 years)... |
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- Case Report
- A Case of Ischemic Enteritis
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Ran Lee, Jeong Kee Seo, Kwi won Park, Jong Je Kim
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Clin Exp Pediatr. 1997;40(2):254-259. Published online February 15, 1997
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Ischemic enteritis is caused by embolism or thrombosis of superior mesenteric artery
and nonocclusive ischemia. Mesenteric venous thrombosis, drugs, and vasculitis are less frequent etiologic factors. In children, occlusion of microcirculation by fibrin thrombi initiated by endotoxemia may be an etiology. Severe abdominal pain, vomiting, and diarrhea with evidence of gross or microscopic bleeding are common presenting symptoms. Angiography may be... |
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- A Case of Intestinal Amebiasis with Protein Losing Enteropathy
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Chan Young Pak, Hee Taeg Kim, Soo Young Choi, Yun Jong Kang, Yeon Chung Chung, Jin Keun Ghang, Jeong Kee Seo
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Clin Exp Pediatr. 1997;40(10):1458-1464. Published online October 15, 1997
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Amebiasis is an infectious disease caused by Entameba histolytica. Amebiasis
remains an extremely important consideration in the differential diagnosis of diarrhea,
especially when there is associated bleeding. It is imperative that appropriate studies to
establish or exclude the diagnosis of amebiasis be carried out in all patients who present
with a clinical and sigmoidoscopic picture of colitis, and that patients treated with
metronidazole for amebiasis... |
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- Original Article
- Recent Changesin Prevalence of Hepatitis B Viral Markers in Preschool Children in Seoul,1995
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Yon Ho Choe, Jeong Kee Seo, Jeong Hwan Yun, Hyo Seok Lee
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Clin Exp Pediatr. 1996;39(9):1254-1259. Published online September 15, 1996
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Purpose : A nationwide hepatitis B vaccination publicity campaign and program was launched
in 1988 in Korea. This survey was designed to evaluate the recent changes of the positive rates
of hepatitis B surface antigen and antibody in sampled preschool children living in Seoul, 1995.
Methods : Study population consisted of 218 preschool children aged 2 to 5 years. Most of
them had been... |
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- Case Report
- A Case Report of Autoimmune Hepatitis Associated with Choledochal Cyst and Pancreatitis
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Kyung Ran Park, Sun Young Lee, Soon Young Kim, Hyoung Shim Chang, Nam Su Back, Chong Jai Kim, Joong Gon Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1996;39(8):1146-1150. Published online August 15, 1996
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Autoimmune hepatitis in children is a rare and severe inflammatory disease of unknown
etiology, and progress to cirrohosis and liver failure, generally is responsive to immunosuppressive
therapy. It is more prevalent in women than men, and characterized by the presence of
circulating autoantibodies, a high serum globulin. Extrahepatic manifestations such as thyroiditis,
ulcerative colitis, glomerulonephritis and autoimmune hemolytic anemia, are associated.
We report, to our... |
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- A Case of Intestinal Neuronal Dysplasia
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Se Young Kim, Yon Ho Choe, Jeong Kee Seo, In One Kim, Chong Jai Kim
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Clin Exp Pediatr. 1996;39(8):1151-1157. Published online August 15, 1996
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Intestinal neuronal dysplasia(IND) is a disease characterized clinically by symptoms of
intestinal obstruction and pathologically by hyperplasia of the submucosal and myenteric plexuses
with formation of giant ganglia. Chronic intestinal pseudo-obstruction is a clinical diagnosis,
composed of myopathic form and neuropathic form, and normal intestinal histology. Intestinal
neuronal dysplasia is a neuropathic form of chronic intestinal pseudo-obstruction. The clinical
presentation and the course of IND... |
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- Case Report
- Four Cases of Congenital Esophageal Stenosis Due to Tracheobronchial Remnants
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Gi Woong Sung, So Young Lee, Yeon Ho Choi, Kyoung Mo Kim, Jeong Kee Seo, In Won Kim, Kwi Won Park, Jong Je Kim
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Clin Exp Pediatr. 1996;39(2):273-279. Published online February 15, 1996
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Esophageal stenosis due to tracheobronchial remnants is a rare cause of congenital esophageal stenosis. The cause is thought to be esophageal sequestration of tracheobronchial remnants during embryonic separation. Errors in diagnosis are common and high index of suspicion is required for accurate diagnosis, and resection of primary site with anastomosis is recommanded. Although a rare entity, esophageal stenosis due to... |
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- Original Article
- The Diagnostic Value of Liver Biopsy in Children with Fever of
Unknown Origin and Hepatosplenomegaly
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Sue Mee Park, Yeon Ho Choi, Jong Jae Kim, Hoan Jong Lee, Jeong Kee Seo
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Clin Exp Pediatr. 1996;39(11):1544-1555. Published online November 15, 1996
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Purpose : Although many strides have been made in the radiological and laboratory diagnosis,
the liver biopsy is still considered an important tool for the diagnosis of liver disease. We report
our experience that histologic investigation of the liver was essential searching for the etiologic
diagnosis in eight children with fever of unknowm origin and hepatosplenomegaly, who's
diagnosis were not documented by other diagnostic... |
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- Caustic Esophagitis and Gastrofiberoscopy in Children
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Hyeon Jeong Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1996;39(11):1556-1564. Published online November 15, 1996
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Purpose : There have been many accidental ingestions of strong acid or alkali in early childhood.
If the patient survives the acute effects of caustic ingestion, the reparative response can result in
esophageal and gastric stenosis. However there have been few endoscopic studies on caustic
esophagitis in children. The aim of this study was to review the contribution of the endoscopy
to the diagnosis... |
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- Case Report
- A case of Primary Sclerosing Cholangitis with Ulcerative Colitis
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Jung Sue Kim, Yon Ho Choe, Chong Jai Kim, Woo Sun Kim, In-One Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1996;39(10):1448-1454. Published online October 15, 1996
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An association between primary sclerosing cholangitis and ulcerative colitis is well known.
But, primary sclerosing cholangitis with ulerative colitis has been rarely reported in children. The
prevalence of primary sclerosing cholangitis among ulcerative colitis patiens is 3% in children.
Primary sclerosing cholangitis is characterised by inflammation and fibrosis of the intrahepatic
and extrahepatic bile ducts. The diagnosis of primary sclerosing cholangitis based on biochemical,
histologic... |
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- A Case of Neonatal Cholestasis with Arthrogryposis Multiplex Congenita and Renal Tubular Insufficiency(ARC Syndrome)
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Hi Soo Rhee, Soon Young Kim, Nam Sun Baik, Il Soo Ha, Jeong Kee Seo
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Clin Exp Pediatr. 1996;39(1):126-130. Published online January 15, 1996
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We report a case of ARC syndrome with arthrogryposis multiplex congenita, renal tubular insufficiency and cholestasis. The Patient presented in the early neonatal period with micrognathia, low set ears, high arched palate, multiple joint contracture, conjugated hyperbilirubinemia and failure to thrive. He died at the age of 1 month despite medical therapy. Findings of renal tubular insufficiency included persistent renal... |
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- A Case of Chronic Pancreatitis Complicated by Hemobilia
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Sang Ook Nam, Jeong Kee Seo, Je Geun Chi, Kyung Mo Yeon
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Clin Exp Pediatr. 1995;38(3):422-427. Published online March 15, 1995
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Hemobilia caused by pancreatic disease is very rare. The most common cause is a splenic artery pseudoaneurysm caused by acute and chronic inflammation of the pancreas.
We experienced a case regarding as hemobilia as a complication of chronic relapsing pancreatitis in a 14 year-old boy. He was admitted with chief complaints of abdominal pain and hematemesis. Two years prior to admission,... |
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- A Case of \Intractable Ulcerating Enterocolitis\" of Infant"
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Ju Young Jeong, Jeong Kee Seo, Kwi Won Park, Je Geun Chi
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Clin Exp Pediatr. 1995;38(2):264-270. Published online February 15, 1995
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Intractable ulcerating enterocolitis of infancy is uncommon, inhereditary disease characterized by ulcerating stomatitis, severe perianal disease, affecting the whole gastrointestinal tract, mainly colon with flask shaped large ulcer. It was first described by Sanderson et al in 5 cases of infant with intractable diarrhea having above clinical manifestation. It should be differentiated with Crohn's disease and Behcet's disease.
We experienced a... |
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- Original Article
- Infantile Choledochal Cyst Presenting with Neonatal Cholestasis; Review of Anatomical and Clinical Aspect
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Jae Won Jeong, Jeong Kee Seo, Kwi Won Park, In Won Kim
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Clin Exp Pediatr. 1995;38(12):1629-1637. Published online December 15, 1995
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Purpose : Extrahepatic biliary atresia, neonatal hepatitis, Allagille syndrome are most common primary causes of the neonatal cholestasis. Infantile choledochal cyst is another primary disease presenting with neonatal cholestasis but its incidence is so low that it has been reported rarely. Choledochal cyst in infancy has been known to have clinically and anatomically different characteristics from ones after infancy. Thus... |
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- Evaluation of Severity of Childhood Pancreatitis with Multiple Factor Scoring Systems
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Young In Choi, Jeong Kee Seo
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Clin Exp Pediatr. 1995;38(12):1653-1663. Published online December 15, 1995
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Purpose : Pancreatitis in children is not common but can be associated with severe morbidity rates. Early prognostic evaluation of acute pancreatitis assists in selecting those patients who should be closely monitored. We studied the clinical characteristics and prognostic factors in patients with acute pancreatitis.
Methods : Twenty five children with pancreatitis were included ranging in age from 1.8 to 14.9... |
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- Prevalence and Its Changes of Hepatitis B Viral Markers from 1988 to 1993 in Korean Children
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Jae Geon Sim, Jeong Kee Seo, Seong Jae Suh
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Clin Exp Pediatr. 1995;38(11):1535-1539. Published online November 15, 1995
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Purpose : Hepatitis B infection is prevalent in Korea and active immunization of Hepatitis B has been proceeded intensively during the last decade. This study was designed to evaluate the changes of the prevalence of hepatitis B surface antigen (HBsAg) and that of antibody (HBsAb) in Korean children from 1988 to 1993. We can estimate the prevalence and tendency of... |
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- Ischemic Hepatitis in Children after Cardiac Operation -Analysis of Clinical Characteristics, Risk Factors and Outcome-
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Kyung Mo Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1995;38(11):1540-1546. Published online November 15, 1995
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Purpose : We have experienced frequently the ischemic hepatitis after cardiac operations which shows rapid striking rise of transaminase. But the ischemic hepatitis in children after cardiac operation is not defined yet in Korea. We examined the clinical characteristics and analyzed the risk factors and outcome in 20 children who showed typical clinical course of ischemic hepatitis after cardiac operation.
Methods... |
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- Uncooked Cornstarch Therapy in Type I Glycogen-Storage Diasese(GSD-I)
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Seon Young Lee, Jeong Kee Seo
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Clin Exp Pediatr. 1995;38(1):36-46. Published online January 15, 1995
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Purpose : A few years ago it was shown that uncooked cornstarch feeding(UCS) could correct the biochemical abnormalities resulting from a deficiency of glucose-6-phosphatase in children with type ment. So far, little experience is available with UCS in Korea.
We studied to compare the effects on biochemical control and growth of therapy with portacaval shunt and therapy with UCS.
Methods : Enghteen... |
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- Case Report
- Longterm Follow Up of A Case of Eosinophilic Gastroenteritis
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So Young Lee, Jeong Kee Seo
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Clin Exp Pediatr. 1995;38(1):104-109. Published online January 15, 1995
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Eosinophilic gastroenteritis(EG) is a rare disease characterised histologically by eosinophilic infiltration of the gut wall. The clinical features depend on which layer and location are involved. Patients may be divided into three clinical groups as predominantly mucosal, muscle layer, or subserosal disease based on the histological site of eosinophilic infiltration of the bowel wall, although there is lften considerable overlap.... |
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- Original Article
- Cricopharyngeal Incoordination in Infancy
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Yong Joo Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1994;37(6):752-758. Published online June 15, 1994
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Cricopharyngeal incoordination of infancy is a rare disease, characterized by difficult swallowing soon after birth. Regurgitation, frequent choking and aspiration with deglutition, recurrent aspiration pneumonia, and to-and-fro movement of the contrast medium in the posterior pharynx on upper esophageal cineroentgenography.
Clinical investigation was performed in the infants who were admitted due to difficult swallowing, reguritation, and recurrent pneumonia from March 1,... |
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- Case Report
- Candida Esophagitis in Infancy-A Report of 3 Cases
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Ho Sung Kim, Youn Woo Kim, Jae Geon Sim, Beom Soo Park, Hoan Jong Lee, Joong Gon Kim, Jeong Kee Seo, Je Geun Chi
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Clin Exp Pediatr. 1994;37(2):269-275. Published online February 15, 1994
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We experienced 3 cases of Candida esophagitis in infancy which were diagnosed by esophageal endoscopy, First case, 10 month-old boy with combined immune deficiency had suffered from oral thrush and poor feeding for more than 4 months. Esophageal endoscopy revealed multiple whitish creamy patches on the friable erythematous and necrotic mucosa of the esophagus, He was firstly treated with amphotericin-B... |
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- Original Article
- Choleithiasis in Childhood
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Soon Young Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1994;37(1):70-77. Published online January 15, 1994
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Nineteen children found to have gallstones at Seoul National University of Children's Hospital form Jun. 1982 to Jun. 1992 wee reviewed.
The results were as follows:
1) The mean age was 10 years, with 9 boys and 10 girls.
Most of the cases (63%) were over 10 years of age.
2) Clinical manifestations were abdominal pain (14 cases), naused and/or vomiting (5 cases), fever... |
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- Esophageal Varix in Children - Endoscopic Evaluation and Clinical characteristics-
-
Soon Young Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1993;36(12):1691-1700. Published online December 15, 1993
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Fifty five children with encoscopically proven esophageal varices form Jul. 1987 to Dec. 1992 were analyzed for endoscopic and clinical characteristics.
The results were as follows :
1) According to etiological classification of portal hypertension in 55 cases, 35 cases showed intrahepatic causes (64%) and cases had extrahepatic causes (36%).
The most common clinical manifestation on admission was hematemesis (42%) and abdominal mass... |
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- Chronic Idiopathic Intestinal pseudo-obstrucion Syndrome in Childhood
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Jae Geon Sim, Jeong Kee Seo, Kui Won Park, Je Geun Chi
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Clin Exp Pediatr. 1993;36(11):1583-1595. Published online November 15, 1993
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Chronic idiopathic intestinal pseudo-obstruction syndrome is a clinical condition induced by an impaired function of intestinal motility. Although its clinical symptoms are those of intestinal obstruction, mechanical obstruction of the intestine cannot be found by vigorous studies, even by operative exploration.
We have experienced nine cases of chronic idiopathic intestinal pseudo-obstruction syndrome. It will help in diagnosis and treatment of the... |
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- A Genetic Linkage Study of Wilson Disease in Korean Families
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Jong Won Kim, Sang In Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1993;36(11):1596-1612. Published online November 15, 1993
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Wilson disease gene (WND) locus is presumed to be located in chromosome 13q. There are studies on the clinical heterogeneities and variations between ethnic groups in Europe, North America, and the Middle East and it requites the study of another ethnic group, especially Asian population for the confirmation.
This study was an analysis of restriction fragment length polymorphism of the Wilson's... |
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- Case Report
- Three Cases of Post-transfusion Hepatitis C
-
Kyung Un No, Ho Seong Kim, Ji Won Choi, Dong Wook Kim, Cheol Ho Jang, Beom Su Park, Jeong Kee Seo, Gyeong Hoon Kang, Je Geun Chi
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Clin Exp Pediatr. 1992;35(9):1255-1262. Published online September 15, 1992
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Hepatitis C virus has been known to be the main cause of post-transfusion non-A, non-B hepatitis. The authors experienced three cases of hepatitis C. All were associated with blood transfusions. They had no specific symptoms, and the levels of aminotransferases were markedly elevated and showed severe fluctuations in two cases. Anti-HCV tested two or three times were all positive, and... |
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- Original Article
- Cytomegalovirus Infection in Children: The Significance of CMV Specific IgM Antibody Test and Virus Isolation in the Urine
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Dong Wook Kim, Hyun Kwack, Seong Hee Jang, I Seok Kang, Hoan Jong Lee, Jung-Hwan Choi, Jeong Kee Seo, Chong Ku Yun
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Clin Exp Pediatr. 1992;35(7):890-901. Published online July 15, 1992
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The clinical pictures of 44 children with IgM antibody to CMV (cytomegalovirus) by ELISA(enzyme linked immunosorbent assay) were reviewed retrospectively, and the significance of serum CMV specific IgM antibody and virus isolation in the urine was analyzed.
Age of the patients with IgM antibody to CMV ranged from 23 days to 8 years 7 months, and median age was 2 months.... |
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- Case Report
- A Case of WDHA(Watery Diarrhea Hypokalemia Achiorhydria) Syndrome
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Nam Seon Beck, Jun Jai Kim, Beom Soo Park, Jeong Kee Seo, Hyo Seop Ahn, Hyung Ro Moon, Je Geun Chi
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Clin Exp Pediatr. 1992;35(4):575-580. Published online April 15, 1992
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VIP secreting tumors are rare in children but they produce a dramatic clinical picture, the most prominent feature of which is profuse, watery diarrhea and hypokalemia. A 5-year-old girl was brought to Seoul National University Children's Hospital for evaluation of profuse watery diarrhea. She presented with watery diarrhea, hypokalemia, and stunted growth, and had experienced these problems for four years... |
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-
- Original Article
- Gastrofiberscopic Findings and Helicobacter pylori Gastritis in Children with Recurrent Abdominal Pain
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Jeong Kee Seo, Je Geun Chi, Eui Chong Kim
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Clin Exp Pediatr. 1992;35(12):1646-1656. Published online December 15, 1992
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Gastrofiberscopic findings and the presence of Helicobacter pylori (H. pylori) were studied prospectively in children with recurrent abdominal pain (RAP). Endoscopic findings in 707 children with RAP revealed that 243 children (34.3%) showed abnormal findings including gastritis in 16.9%, duodenitis in 10.4%, esophagitis in 5.7%, duodenal ulcer in 5.7%, and gastric ulcer in 1.1% of children with RAP.
Endoscopic biopsy of... |
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- Case Report
- A Case of Intestinal Lymphangiectasia
-
Yae Kyung Suh, Kyung Hee Park, Chul Ho Jang, Bum Soo Park, Jeong Kee Seo, Sung Hae Park, Je Geun Chi, Kyung Mo Yeon, Kwi Won Park
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Clin Exp Pediatr. 1992;35(12):1737-1743. Published online December 15, 1992
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Intestinal lymphangiectasia is a primary or secondary disorder of the gastrointestinal tract, which is associated with lymphatic dysfuction and protein-losing enteropathy. It's clinical manifestations vary widely, but the main symptoms are abdominal distention, edema, abdominal pain and growth failure.
We described a 15-yr-old boy, who suffered from above symptoms since third year of his age and diagnosed by duodenal endoscopy which... |
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- Two Cases Antral Webs and One Case of Pyloric Web in Children
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Young Mee Yoo, Hann Tchaha, Jeong Kee Seo, Kui Won Park, Woo Ki Kim, Kyung Mo Yeon
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Clin Exp Pediatr. 1992;35(10):1411-1418. Published online October 15, 1992
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Antral or prepyloric mucosal diaphragms (webs) are composed of mucosa which enclose a membrane of submucosa and located at the antrum of the stomach at variable distances from the pylorus. They may be congential in origin or secondary to chronic peptic ulcer disease. Obstructive symptoms occur when diaphragmatic aperture is less than 1 centimeter. The diagnosis relies on the history,... |
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- A Case of Chronic Intestinal Pseudo-obstruction Syndrome
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Hye Won Park, Chul Ho Chang, Bum Soo Park, Jeong Kee Seo, Sung Hye Park, Je Geun Chi, Kyung Mo Yeon, Kui Won Park
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Clin Exp Pediatr. 1992;35(10):1427-1434. Published online October 15, 1992
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Chronic intestinal pseudo-obstruction is a clinical condition in which impaired intestinal propulsion causes recurrent symptoms of bowel obstruction in the absence of mechanical occlusion.
In this paper a female neonate was presented with vomiting and abdominal distension in the first few days of life but passed normal meconium. Barium enema showed a microcolon and an abnormaly sited cecum. Malrotation of bowel... |
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-
- Original Article
- Endoscopic evaluation for gastrointestinal hemorrhage in childhood.
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Cheol Ho Chang, Beom Soo Park, Jeong Kee Seo
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Clin Exp Pediatr. 1991;34(4):515-524. Published online April 30, 1991
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The diagnosis and management of gastrointestinal tract hemorrhage in infants and children have
been changed dramatically over the past decade. Although previous reviews of this subject have
suggested that the cause of gastrointestinal tract bleeding may remain obscure in many patients,
recent experience indicates that this is now uncommon. This advance is largely a result of the
widespread and now routine application of fiberoptic... |
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- A case of Caroli's disease.
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Seong Hee Jung, Cheol Ho Chang, Han Tchah, Jeong Kee Seo, Kwi Won Park, In One Kim, Kyung Mo Yeon, Je Geun Chi
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Clin Exp Pediatr. 1991;34(2):261-266. Published online February 28, 1991
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Caroli’s disease was first described by Caroli in 1958 and characterized by segmental cystic
dilatation of the intrahepatic bile ducts. There is stasis of bile with stone formation in the dilatated
ducts, giving rise to frequent attacks of pain and cholangitis.
In the past, diagnosis of the Caroli’s disease is rarely established prior to operation and subsequent
cholangiography. Recently, with ultrasonography, computerized tomography, radioisotope... |
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- Three Cases of Typhlitis during Treatment for Acute Myelocytic Leukemia in Children.
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Soon Mee Park, Il Soo Ha, Hoan Jong Lee, Jeong Kee Seo, Hyo Seop Ahn, Kyung Mo Yeon
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Clin Exp Pediatr. 1989;32(10):1455-1462. Published online October 31, 1989
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Typhlitis is a rare necrotizing colitis in which inflammation is confined to cecum. It occurs during
chemotherapy for malignancies, in terminal stage of aplastic anemia, in transplant patients. The
pathogenesis of typhlitis has included leukemic infiltration of the bowel, thrombocytopenia, direct
toxic effects of chemotherapy, steroid, bacterial invasion of the bowel wall secondary to neutropenia
and alteration of the bowel flora by broad-spectrum antibiotics.... |
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- Manometric Response to Heller's Myotomy in Achalasia.
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Chun Wha Lee, Kyung Mo Kim, Jeong Kee Seo, Hyung Ro Moon, Joo Hyun Kim
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Clin Exp Pediatr. 1989;32(1):101-108. Published online January 31, 1989
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Achalasia is an espohageal motility disorder. It is characterized by the loss LES relaxation on
swallowing and of esophageal peristalsis and results in dysphagia, regurgitation and substernal pain.
Manometry is one of several diagnostic tests of achalasia and reveals
1) Complete absence of esophageal peristalsis,
2) hypertension of LES. 3) impaired sphincter relaxation on swallowing and 4) positive esophageal
body pressure compared to intragastric pressure.
We... |
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- A Clinical Observation on Esolhageal Atresia and Tracheoesophageal Fistula.
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In Sang Jeon, Jung Hwan Choi, Jeong Kee Seo, Chong Ku Yun, Sung Chul Lee, Kwi Won Park, Woo ki Lee
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Clin Exp Pediatr. 1988;31(6):691-699. Published online June 30, 1988
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To study the clinical characteristics of esophageal atresia and tracheoesophageal fistula, we
carried out a retrospective review on medical records of 39 patients who were diagnosed as that by
the operation, autopsy or radiolgy at the department of Pediatrics and Pediatric Surgery, Seoul
National University Hospital between January 1980 and June 1987.
The results were summarized as follows;
1) Type A was most common (94.8%) among... |
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- A Case of Familial Dysautonomia.
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Hong Jin Lee, Dong Kyu Jin, Sei Won Yang, Jeong Kee Seo, Hyung Ro Moon, Je Geun Chi
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Clin Exp Pediatr. 1988;31(5):648-654. Published online May 31, 1988
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Few documented cases of Familial dysautonomia fulfilling current diagnostic criteria have been
recognized in non-Jews especially in orientals. In our case diagnosis was established in 8 year old
Korean girl. She fulfilled 8 out of 9 essential diagnostic criteria of Riley. It represents a report of
this syndrome with achalasia and improved with modified Heller’s myotomy. |
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- The Abeominal Tuberculosis in Children.
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Young Sik Kim, Jeong Hun Ha, Jeong Kee Seo
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Clin Exp Pediatr. 1988;31(12):1594-1602. Published online December 31, 1988
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following results were obtained through the clinical review of 29 cases with the abdominal
tuberculosis under the age of 15 years, who admitted to Seoul National University Hospital from
January, 1977 to December, 1987.
1) Thirteen cases were patients with tuberculous peritonitis, 12 cases were patients with intestinal
tuberculosis, and the remaining 4 cases were patients with both tuberculous peritonitis and intestinal
tuberculosis.
2) The male to... |
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- Syndrome of Inappropriate Secretion of Antidiuretic Hormone(SIADH) in Acute Respiratory Diseases.
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Young Jee KIm, Young Yull Koh, Jeong Kee Seo, Hung Ko Moon
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Clin Exp Pediatr. 1987;30(9):1021-1028. Published online September 30, 1987
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The SIADH incidence and relevant factors in acute respiratory diseases were evaluated in 461
children with over 28 days old, hospitalized for bronchiolitis, viral pneumonia, bacterial pneumonia,
mycoplasma pneumonia and asthma, without other causes of electrolyte imbalance.
The overall incidence of SIADH in acute respiratory diseases was 11.93%. The incidence in
mycoplasma pneumonia (19.05%) was highest and incidence in bacterial pneumonia (17.42%), viral
pneumonia (9.17%),... |
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- Clinical Observation on Splenectomized Children.
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Mi Ryung Um, Jae Won Song, Yong Yull Koh, Jeong Kee Seo, Hyo Seop Ahn, Chang Yee Hong, Kwi Won Park
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Clin Exp Pediatr. 1987;30(5):511-517. Published online May 31, 1987
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A clinical study was performed on 26 cases of splenectomized children who had been seen at the
Department of Pediatrics, Seoul National University Hospital, during the period of 7 years 7 months
from January 1978 to July 1985.
The results were as follows:
1) Primary diseases were hereditary spherocytosis (8 cases), Hodgkin disease for staging laparotomy (8 cases),
... |
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- A Clinical Observation on Fulminant Hepatitis in Children.
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Hoan Jong Lee, Jeong Kee Seo, Hyung Ro Moon
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Clin Exp Pediatr. 1987;30(4):406-415. Published online April 30, 1987
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Twenty-seven cases of fulminant hepatitis in children were retrospectively analyzed. The overall
survival rate was 11%. The interval between onset of encephalopathy and death, and that between
jaundice and death were 2-26 days (median 4 days), 4-61 days (median 14 days), respectively.
HBs antigenemia was detected in 24%, HAV IgM was negative in 5 patients tested, and 4 cases
were suspected as non-A, non-B... |
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-
- Case Report
- A Case Report of Caroli's Disease.
-
Hun Jong Chung, Jeong Kee Seo, Kwang Wook Ko, Kwi Won Park, Woo Ki Kim
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Clin Exp Pediatr. 1985;28(7):731-736. Published online July 31, 1985
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A case of Caroli's disease was presented and review of the literature was done. The patient was a 3 year old girl and had recurrent episodes of jaundice, abdominal pain and vomiting. Dilatation of the left intrahepatic bile duct was clearly shown on the operative cholangiography.
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-
- Original Article
- Primary Peritonitis in Children with Nephrotic Syndrome.
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Hae Il Cheong, Whan Jong Lee, Jeong Kee Seo, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1985;28(7):695-704. Published online July 31, 1985
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Thirty episodes of primary peritonitis in 22 children with nephrotic syndrome who had admitted in the Department of Pediatrics, Seoul National University Hospital from Jan. *81 to Sept. ’84 were studied, and the results were as follows; 1)Among 22 children, male to female ratio was 16 : 6 and the mean age at the onset of
peritonitis was 7.80 years (average... |
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- Primary Immunode Ficiency Disorders in Infancy and Childhood.
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Hoan Jong Lee, Jung han Choi, Jeong Kee Seo, Hyo Sup Ahn, Kwang Wook Ko
-
Clin Exp Pediatr. 1985;28(3):263-282. Published online March 31, 1985
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The immunodeficiency disorders are a diverse group of illness which results from defectsin one or more of the four major mechanisms of immune system-antibody-mediated(B cell) immunity, cell-mediated(T cell) immunity, phagocytosis, and complements. Though immunodeficiency disorders are uncommon, the possibility should be considered in any individuals with recurrent or persistent infection. During the period between January, 1973 and October, 1984, we... |
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- Case Report
- A Case of Niemann-Pick Disease with Sea-Blue histiocytes in the Bone Marrow.
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Young Sun Kim, Soo Heum Lim, Jeong Kee Seo, Hyo Seop Ahn, Hyung Ro Moon
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Clin Exp Pediatr. 1985;28(12):1238-1244. Published online December 31, 1985
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A case of Niemann-Pick disease in a 12 year and 6 month old Korean male was reported. The patient showed marked hepatosplenomegaly without neurologic symptoms. Fundoscopic examination revealed a cherry-red spot with white ring in the maculae. Numerous foamy histiocytes and sea-blue histiocytes were seen in the bone marrow. The liver biopsy specimen showed the diffuse ballooning of hepatocytes obliterating... |
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-
- Two Case of Watson-Alagille Syndrome.
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Heon Seok Han, Soo Heum Lim, Young Sun Kim, Jeong Kee Seo, Hyung Ro Moon
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Clin Exp Pediatr. 1985;28(10):1047-1051. Published online October 31, 1985
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Watson-Alagille syndrome (Arteriohepatic dysplasia, Syndromatic paucity of interlobular bile duct), a disease characterized by chronic liver disease, characteristic facies, cardiova scular abnormalities, and vertebral arch abnormalities has paucity of interlobular bile ducts on histologic examination of liver. We experienced two cases of Watson-Alagille syndrome in a 7-month-old male infant and a 12-month-old male infant who had the chief complaint of... |
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-
- Original Article
- Clinical Review of Abdominal Masses in Infant and Children .
-
Dong Hyun Choo, Chong Young Pakr, Sang Pok Suk, Jeong Kee Seo, Hyo Seop Ahn, Kwang Wook Ko
-
Clin Exp Pediatr. 1984;27(12):1202-1212. Published online December 31, 1984
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|
One hundred and ninety four patients who were admitted with the chief complaint of
abdominal mass were reviewed. The result were as follows;
1) The common abdominal masses in infants and children were neuroblastoma, Wilms
tumor, germ cell tumor, hydronephrosis and hepatoblastoma in decreasing order of frequency.
Malignant tumors were 114 cases and benign tumors were 69 cases.
2) The male:female ratio was 110 : 84. In... |
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-
- A Clinical Study of Reye`s Syndrome.
-
Young Seo Park, Hwan Jong Lee, Sang Pok Suk, Jeong Kee Seo, Kwang Wook Ko
-
Clin Exp Pediatr. 1984;27(11):1088-1096. Published online November 30, 1984
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|
Seventy-four cases of Reye’s syndrome, diagnosed during the period of 1978-1983 at the
Pediatric ward of Seoul National University Hospital, were studied on the clinical features
and laboratory findings.
The following results were obtained;
1) The annual incidence was increasing year by year and the monthly incidence was highest in September.
2) The sex ratio of male to female was 1.2:1. The highest incidence was showed between... |
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-
- Lipoprotein Profiles in Minimal Change Nephrotic Syndrome.
-
Yong Choi, Heui Jeen Kim, Hae Il Cheong, Jeong Kee Seo, Kwang Wook Ko
-
Clin Exp Pediatr. 1983;26(3):237-246. Published online March 31, 1983
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Data obtained from 59 hospitalized patients with minimal change nephrotic syndrome which
was confirmed by kidney biopsy, were analyzed for serum albumin, serum lipids, 24hr urine
protein, creatinine clearanee, HDL-eholesterol. In 38 of the patients, lipoproteins were analyzed.
The following results were obained
1. Serum phospolipid (PL) was increased whenever serum total cholesterol (TC) was
increased but to a lesser degree. The ratio of TC/PL were... |
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-
- CNS Lesions in Tuberculous Meningitis.
-
Hee Young Shin, Jung Hwan Choi, Jeong Kee Seo, Kyung Mo Yeon, Kwang Wook Ko, Hahn Woong Choe
-
Clin Exp Pediatr. 1983;26(3):213-219. Published online March 31, 1983
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|
Clinical features of 20 patients who were diagnosed as tuberculous meningitis at Seoul
National University Hospital from Jan. ’82 to Dec. ’82 were analyzed with special respect
to their computed tomographic findings of the brain. Age at the onset of the disease ranged from 7 month.
to 12 9/12 year with the mean age of 3 11/12 year. Fifteen cases were under... |
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-
- Role of Enterotoxogenic E.Coli in Acute Diarrhea of Childhood in Korea.
-
Kwang Wook Ko, Jeong Kee Seo, Woo Hyun Chang, Moon Kyo Kim, Nam Ung Yang, Myoung Sik Choi
-
Clin Exp Pediatr. 1983;26(10):949-958. Published online October 31, 1983
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|
To determine the role of enterotoxigenic Escherichia coli in diarrheal disease of non-hosp-
italized children living in Korea, stool specimens were collected from 330 patients with dia-
rrhea and 68 age and sex matched control.
Sixty-eight healthy children and 330 diarrheal patients, who visited three private clinics
and one municipal hospital in Inchon City, were tested to detect the production of Escherichia coli enterotoxin... |
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-
- Case Report
- Two Case of Ginaotti-Crosti Syndrome.
-
Jae Ho Lee, Soon Ung Kang, Jeong Kee Seo, Hyo Seop Ahn, Kwng Wook Ko, Won Suk Kim
-
Clin Exp Pediatr. 1982;25(12):1289-1294. Published online December 31, 1982
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|
The Gianotti-Crosti syndrome is an. infrequently recognized disorder with distinctive clinical
features. We have experienced two cases of Gianotti-Crosti syndrome diagnosed by clinical
manifestation, laboratory data and histopathologic finding of skin.
Case one; An 18-month-old girl was admitted to the pediatric ward with the chief complaint
of erythematous rash. Its onset was preceded by an. upper respiratory tract infection. She
had a wide spread erythematous... |
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-
- Hyaline Membrane Disease (Five cases report including two autopsy cases).
-
Jun Hee Kang, Young Min Ahn, Joong Gon Kim, Chun Haeng Park, Jeong Kee Seo, Ok Ja Hwang, Chong Ku Yun, Yoon Seong Lee, Shin Eun Choi, Je G Chi
-
Clin Exp Pediatr. 1981;24(9):882-890. Published online September 15, 1981
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The hyaline membrane disease is not a common disease in Korea. Only a few reports of small scale are avaiable in the literature. We have experienced 5 cases of HMD during approximately 1 year period. The diagnosis was made either on characteristic clinical and roentgenological features or postmortem examination. The birth weights of these cases were in the range of... |
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-
- Original Article
- Clinical Obseervation for Hematologic Disorders in Children.
-
Eung Sang Choi, Soon Ung Kang, Jeong Kee Seo, Hyo Seop Ahn, Chang Yoo Hong
-
Clin Exp Pediatr. 1981;24(3):235-244. Published online March 15, 1981
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Nine hundred and twenty-three cases of hematologic disorders in children who were admi-tted to department of pediatrics, SNUH, from 1955 to Oct. 1980 were analysed. The patients consisted of 624 males and 299 females. The results were as follows; 1.Mean annual percentage of hematologic patients among total admitted patients was 6.8%. 2.The peak age incidence of various hematologic disorders was... |
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-
- The Incidence of HBs Antigenemia in Glomerular Desease and Control Group in Children.
-
Yong Choi, Whan Jong Lee, Jeong Kee Seo, Kwang Wook Ko
-
Clin Exp Pediatr. 1981;24(2):122-127. Published online February 15, 1981
-
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|
HBsAg, HBcAb and HBsAb were examined with radio-immunoassay in 265 patients with glomerular disease, who were admitted to wards or visited to outpatient clinics of department of pediatrics, Seoul National University Hospital, from Jan., 78 to Oct. 80, and in 576 control group, with other than liver disease and without history of transfusion. The incidence in glomerular disease was 10.2%(27... |
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-
- Follow-up Study of Children with Nephrotic Syndrome
-
Jeong Kee Seo, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1976;19(12):893-903. Published online December 31, 1976
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Forty seven children with nephrotic syndrome were studied. No specific cause for nephrotic syndrome was found in all children except one with tridione induced nephrotic syndrome. Response to the initial continuous steroid therapy, relapsing patterns and factors affecting prognosis were evaluated in this study. All patients were followed up for more than 3 years. The mean period of observation was... |
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