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Correlation of Body Mass Index, Body Fat Distribution, Aminotranferases and Computed Tomography in Obese Children with Fatty Liver

Korean Journal of Pediatrics 2005;48(3):276-283.
Published online March 15, 2005.
Correlation of Body Mass Index, Body Fat Distribution, Aminotranferases and Computed Tomography in Obese Children with Fatty Liver
So Eun Park1, Hye Ran Yang1, Ju Young Chang1, Jae Sung Ko1, Jeong Kee Seo1, Whal Lee2, Woo Sun Kim2
1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
2Department of Radiology, Seoul National University College of Medicine, Seoul, Korea
비만을 동반한 소아 지방간 환아에서 체질량 지수, 체지방 분포, 간 효소치 및 복부 CT 소견과의 상관관계에 대한 연구
박소은1, 양혜란1, 장주영1, 고재성1, 서정기1, 이활2, 김우선2
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 방사선과학교실
Correspondence: 
Jeong Kee Seo, Email: jkseo@snu.ac.kr
Abstract
Purpose
: Visceral fat accumulation plays a major role in metabolic complications of obesity. It is known that nonalcoholic fatty liver in obese adults is associated with visceral fat accumulation. Body mass index(BMI) is used as the index of obesity in children. The aim of this study is to evaluate the correlation of BMI and visceral adipose tissue(VAT), and the correlation of BMI, body fat distribution, aminotransferases, and severity of fatty liver.
Methods
: Twenty three obese children with fatty liver diagnosed by non-contrast abdominal computed tomography(CT) were included in this study. Data on BMI, aminotransferase levels were collected from clinical records. Visceral adipose area was evaluated with CT.
Results
: BMI had a singnificant correlation with VAT(r=0.51719, P=0.0115). The severity of fatty liver had no significant correlations with BMI(r=-0.11938, P=0.5876), VAT(r=-0.31234, P=0.1468), aspartate aminotransferase(AST)(r=0.12729, P=0.5628) or alanine aminotransferase(ALT)(r=-0.00179, P= 0.9935).
Conclusion
: BMI in obese children was correlated with VAT. But the severity of fatty liver cannot be assessed by BMI, VAT or aminotransferase levels.
Key Words: Obesity , Fatty liver , Body mass index , Fat distribution , Computed tomography


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