| Two Case of Ginaotti-Crosti Syndrome. |
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Jae Ho Lee1, Soon Ung Kang1, Jeong Kee Seo1, Hyo Seop Ahn1, Kwng Wook Ko1, Won Suk Kim2 |
1Department of Pediatrics, College of Medicine, Seoul National University
2Department of Dermatology, College of Medicine，Seoul National Uuiversity |
| Gianoti-Crosti 증후군 2례 |
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이재호1, 강순웅1, 서정기1, 안효섭1, 고광욱1, 김원석2 |
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 피부과학교실 |
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| Abstract |
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The Gianotti-Crosti syndrome is an. infrequently recognized disorder with distinctive clinical
features. We have experienced two cases of Gianotti-Crosti syndrome diagnosed by clinical
manifestation, laboratory data and histopathologic finding of skin.
Case one; An 18-month-old girl was admitted to the pediatric ward with the chief complaint
of erythematous rash. Its onset was preceded by an. upper respiratory tract infection. She
had a wide spread erythematous papular skin eruption of non-itching and of 1 to 5mm in
diameter. It spread from the lower extremity, buttock, upper extremity to face. Associated
finding were cervical lymphadenopathy, anicteric hepatitis, which lasted about 2 months, and
HBs antigenemia. Histopathological examination of a biopsy specimen, obtained from the lower
leg showed focal parakeratosis with mild spongiosis of epidermis and mononuclear cell infi-
ltration in the upper dermis.
Case two; A 14-year-old boy was admitted with the chief complaints of high fever and an.
erythematous papular skin rash. The fever was controlled soon. He had a wide spread
erythematous papular skin eruption of non-itching on the face, limbs and buttock. The significant
findings were cervical lymphadenopathy, anicteric hepatitis and HBs antigenemia.
We report the two cases of Gianotti-Crosti syndrome with review of the related literature.
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| Key Words:
Gianotti-Crosti syndrome, HBs antigenemia. |
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