Journal of the Korean Pediatric Society 1992;35(12):1646-1656.
Published online December 15, 1992.
Gastrofiberscopic Findings and Helicobacter pylori Gastritis in Children with Recurrent Abdominal Pain
Jeong Kee Seo1, Je Geun Chi2, Eui Chong Kim3
1Department of Pediatrics, Seoul National Universty College of Medicine, Seoul, Korea
2Department of Pathology, Seoul National Universty College of Medicine, Seoul, Korea
3Department of Clinical Pathology, Seoul National Universty College of Medicine, Seoul, Korea
반복성 복통증 환아에서의 내시경 소견 및 H. Pylori 위염
서정기1, 지제근2, 김의종3
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 병리학교실
3서울대학교 의과대학 임상병리학교실
Abstract
Gastrofiberscopic findings and the presence of Helicobacter pylori (H. pylori) were studied prospectively in children with recurrent abdominal pain (RAP). Endoscopic findings in 707 children with RAP revealed that 243 children (34.3%) showed abnormal findings including gastritis in 16.9%, duodenitis in 10.4%, esophagitis in 5.7%, duodenal ulcer in 5.7%, and gastric ulcer in 1.1% of children with RAP. Endoscopic biopsy of the antrum showed chronic active gatritis in 25.2%, chronic gastritis in 64.7%, and no abnormalities in 10.1% of children with RAP. H. pylori was investigated by urease test, Giemsa stain and culture method with endoscopic biopsy specimens in 159 children with RAP; 27% of them showed H. pylori gastritis. In 82.5% of children with chronic active gastritis, H. pylori was postitive. Forty three percent of the H. pylori gastritis showed multiple micronodules in the antrum. Wheather H. pylori causes or is coincidentally associated with RAP are unknown. Further active endoscopic investigations in children with RAP are needed to elucidate the role of the endoscopic and histologic abnormalities, or the presence of H. pylori on the pathogenesis of RAP.
Key Words: Recurrent abdominal pain, Gastrofiberscopy, Helicobacter pylori, Children


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