- Clinical Lecture
- Approach to the Children with Recurrent Infections
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Jae Ho Lee
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Clin Exp Pediatr. 2005;48(5):461-468. Published online May 15, 2005
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The major function of immune system is to protect infections. The immune systems are composed of innate and adaptive immunity. In adaptive immunity, the cellular and humoral components interact each other. Neonates and infants are infected frequently, because immune systems are naive and easy to expose to infectious agents. The complete history and physical examination is essential to evaluate the... |
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- The Clinical Significance of Cerebrospinal Fluid Interleukin-6 Levels in Viral Meningitis
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Eun Joo Ju, In Chul Ahn, Jae Ho Lee
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Clin Exp Pediatr. 2000;43(4):496-501. Published online April 15, 2000
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Purpose : Cytokines found at a inflammatory site may be a good indicator of clinical severity of an infectious inflammatory disease. We assayed interleukin 6(IL-6) concentrations in cerebrospinal fluid(CSF) from patients affected with viral meningitis, and verified the relationship between IL-6 and inflammatory parameters and whether IL-6 can be used as a diagnostic marker in the diagnosis of viral meningitis.
Methods... |
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- Immunologic Characteristics of CATCH 22 Syndrome
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Hye Young Ryu, Eun Kyung Jo, Eun Jung Cheon, Hong Ryang Kil, Jae Ho Lee
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Clin Exp Pediatr. 2000;43(11):1423-1429. Published online November 15, 2000
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Purpose : Microdeletion of chromosome 22q11.2 are associated with DiGeorge syndrome(DGS), velocardiofacial syndrome(VCFS) and conotruncal anomaly face syndrome(CTAFS). DGS was originally described as an immunodeficiency disorder secondary to impaired T cell production due to thymic aplasia or hypoplasia. But the frequency & severity of immunodeficiency of other clinical syndromes associated with the chromosome 22q11 deletion has not been investigated. This... |
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- A Study of Serum Cytokines in Nephrotic Syndrome
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Mea Young Chang, Jae Ho Lee
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Clin Exp Pediatr. 1997;40(12):1701-1706. Published online December 15, 1997
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Purpose : It has been reported that patients with nephrotic syndrome have high serum IgE value
and IL-4 involve in IgE synthesis, IL-6 is an autocrine growth factor for the proliferation of
mesangial cells. We studied association between serum cytokines and of nephrotic syndrome.
Methods : We measured serum IL-6, IL-4, IFN-Υ, CD23 in 14 children with nephrotic syndrome
and 3 healthy children by... |
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- Antibody Response to Capsular Polysaccharide Vaccine of Streptococcal Pneumonia in Patients with Nephrotic Syndrom
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Ji Young Choi, Jae Ho Lee
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Clin Exp Pediatr. 1995;38(8):1107-1115. Published online August 15, 1995
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Purpose : Although the etiology and pathogenesis of child with nephrotic syndrome remains uncertain, it has been suggested from indirect evidence that this syndrome may represent deficiency in T-cell function and abnormal humoral immune response to antigens or immynoglobulin. Children with nephrotic syndrome are susceptible to pneumococcal infection. Now, we performed this study to evaluate pneumococcal anticapsular antibody concentration and... |
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- Clinical Studies of Measles in Infancy - Emphasizing on Measles Specific IgG Antibody -
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Jae Ho Lee, Shin Hye Moon
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Clin Exp Pediatr. 1995;38(7):907-913. Published online July 15, 1995
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Purpose : This study was investigated the efficacy of maternal measles specific IgG antibody and the optimal age for measles vaccination in susceptable infant during epidemics
Methods : We evaluated the clinical manifestations and complications of 50 measles infants who were clinically and serologically diagnosed as measles and had not been vaccinated acco-rding to the presense of measles specific IgG antibody... |
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- Prevalence of Diabetes Mellitus and Glycosuria in School children
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Jae Ho Lee, Kwang Wook Ko
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Clin Exp Pediatr. 1994;37(7):986-993. Published online July 15, 1994
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An epidemiological survey on the glycosuria was conducted on the senier students of middle and hign school in Seoul, from March 1981 to March 1982. Selected examinee totalled to 254,835 of which 138,116 were male & 116,719 were female. The initial, second and third urine sugar test were done with Combur-test strip? Glucose tolerance test was performed on those who... |
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- A Case of Acute Rhenmatic Fever Associated with Acute Poststreptococcal Glomerulonepheitis.
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Ho Kyung Choi, Dong Seok Choi, Jae Ho Lee, Young Hun Chung, Hyon Soon Lee
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Clin Exp Pediatr. 1989;32(12):1744-1748. Published online December 31, 1989
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A case of acute glomerulonephritis in association with acute rheumatic fever was presented. The
patient rheumatic arthritis and carditis with mitral insufficiency, who had been diagnosed as acute
poststreptococcal glomeruoonephritis with non-oliguric renal failure with renal biopsy and laboratory
findings.
The patient was treated, and symptom and sign were improved. |
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- A Case of Systemic Lupus Erythematosus Accompanied with Nephritis and Arteritis.
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Oh Kyun Kwon, Hong Yang Khil, Jae Ho Lee, Young Hun Chung
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Clin Exp Pediatr. 1987;30(11):1311-1317. Published online November 30, 1987
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The systemic lupus erythematosus (SLE) is a chronic inflammatory disease involving skin, kidney,
serous membrane, nervous system and other organs.
We experienced a case of SLE accompanied with nephritis and arteritis on the region of the left
thigh, diagnosed by clinical, serologic, immunologic, radiologic and pathologic evaluations.
A 15 years old female patient was admitted to pediatric ward due to sustained pain on left... |
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- Case Report
- Clinical & Animal experimental observation on the Botulism Poisonig in a Family.
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Yeong Du Lee, Yang Weon Lee, Jae Ho Lee, Yong Hun Chung
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Clin Exp Pediatr. 1985;28(9):906-911. Published online September 30, 1985
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Five patients in a family were admitted to the department of peditrics and medicine, CNUH on July 17th, 1984 because of respiratory arrest after ingestion of the rotten sausage. All four children of five patients were expired, but only adult patient was recovered completely. Epidemiological outbreak, clinical course and animal toxin challenge test were compatible with botulism poisoning.
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- Original Article
- A Clinical Study of Cor Triatriatriatum.
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Jae Ho Lee, Il Suck Chang, Nam Su Kim, Yong Soo Yoon, Chang Yee Hong
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Clin Exp Pediatr. 1983;26(11):1070-1080. Published online November 30, 1983
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Cor triatriatum is a rare congenital cardiac anomaly in which the left atrium is divided
into two chambers by an abnormal fibro-muscular septum with, a small opening or not, product pulmonary venous obstruction and pulmonary hypertension. Three cases of cor triatriatum were observed at
the Dept, of Pediatrics, Seoul National University.
Each patient had no specific problem during early infancy, and presented... |
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- Case Report
- A Case of Trensient Myeloproliferative Disorder with Down Syndrome.
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Dong Gyoon Kim, Jae Ho Lee, Jung Il Noh, Hyo Seop Ahn, Chang Yee Hong
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Clin Exp Pediatr. 1983;26(10):1024-1028. Published online October 31, 1983
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Transient myeloproliferative disorder has been reported in infants with Down syndrome.
Infants with Down syndrome and this transient myeloproliferative disorder often present
with signs and symptoms that are clinically and hematologically indistinguishable from
congenital acute myelogenous leukemia. In contrast to congenital AML, complete clinical and
hematological recovery occurs within weeks to months of diagnosis without any specific anti-
leukemic treatment.
A case of transient myeloproliferative disorder... |
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- Two Case of Ginaotti-Crosti Syndrome.
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Jae Ho Lee, Soon Ung Kang, Jeong Kee Seo, Hyo Seop Ahn, Kwng Wook Ko, Won Suk Kim
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Clin Exp Pediatr. 1982;25(12):1289-1294. Published online December 31, 1982
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The Gianotti-Crosti syndrome is an. infrequently recognized disorder with distinctive clinical
features. We have experienced two cases of Gianotti-Crosti syndrome diagnosed by clinical
manifestation, laboratory data and histopathologic finding of skin.
Case one; An 18-month-old girl was admitted to the pediatric ward with the chief complaint
of erythematous rash. Its onset was preceded by an. upper respiratory tract infection. She
had a wide spread erythematous... |
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- Original Article
- Pericardial Effusion in Patients with Rheumatic Fever.
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In Suck Seo, Hee Ju Kim, Jae Ho Lee, Yong Soo Yoon, Yong Choi, Chang Yee Hong
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Clin Exp Pediatr. 1982;25(12):1225-1233. Published online December 31, 1982
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Pericarditis denotes worse prognosis in patients with rheumatic fever. During the period of
4 years from Jan. 1978 to Dec. 1981, one hundred and eighteen patients were diagnosed as
rheumatic fever on the basis of revised Jones* criteria. One hundred and one patients of
them were evaluated with M-mode echocardiography, and were analysed according to Horo-
witz^ classification of pericardial effusion.
The results were as... |
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- Shigelle, and Salmonella.
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NamSu Kim, Jae Ho Lee, Chang Yee Hong
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Clin Exp Pediatr. 1982;25(11):1106-1119. Published online November 30, 1982
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1. A total of 3,178 strains of Staphylococcus aureus, 278 strains of Shegella and 506 strains
of Salmonella were isolated and tested for sensitivity against antimicrobial agents at Seoul
National University Hospital from January 1971 to December 1980. Clinical study was made
on children under 15 years old.
2. Sensitive strains to antimicrobial agents were more frequently isolated in children than
adult. But the pa竹ern of sensitivity... |
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- Histiocytic Medullary Reticulosis in Children: Report of Four Cases and Analysis of Previously Reported Cases.
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Eue Cho Yang, Jae Ho Lee, Soon Ung Kang, Hyo Seop Ahn, Chang Yee Hong, Je G Chi, Yong Il Kim
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Clin Exp Pediatr. 1981;24(10):928-941. Published online October 15, 1981
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Histiocytic Medullary Reticulosis(H.M.R.) is a rapidly progressing fatal disease seen most often in adults, but it has been reported in children younger than 15 years of age. H.M.R. is clinically characterized by fever, wasting generalized lymphadenopathy and hepatosplenomegaly. In the terminal stage, jaundice, purpura, anemia and pancytopenia are all present with or without skin involvement. Cardinal pathologic features are systemized... |
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