- Original Article
- Catch up growth in children born small for gestational age by corrected growth curve
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Myung Ki Jung, Ji Eun Song, Seung Yang, Il Tae Hwang, Hae Ran Lee
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Clin Exp Pediatr. 2009;52(9):984-990. Published online September 15, 2009
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Purpose:Being small for gestational age (SGA) is a risk factor of short stature in children. Genetic background such as mid-parental height (MPH) is known to influence growth of children born SGA. We studied the relationship between growth of children born SGA and MPH and studied the effects of insulin-like growth factor (IGF-I) and insulin-like growth factor binding protein 3 (IGFBP-3)... |
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- The relationship between adiponectin, leptin, insulin, insulin-like growth factor and IGF binding protein-3 in cord blood and neonatal anthropometric parameters
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Hai Jung Cho, Ji Young Kim, Me Jin Kim, Il Tae Hwang, Hae Ran Lee
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Clin Exp Pediatr. 2008;51(7):722-728. Published online July 15, 2008
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Purpose : This study was designed to examine the effects of adiponectin, leptin, insulin, insulin-like growth factor (IGF)-I and IGF binding protein (BP)-3 levels in cord blood on weight, length, and adiposity at birth in healthy term infants. In addition, we evaluated the mechanism to change the hormone levels in appropriate for gestational age (AGA) during the first month.
Methods :... |
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- The usefulness of skin test in evaluation of immunity to varicella
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Ji-Young Kim, Hye Jeen Lee, Me Jin Kim, Young Ho Kim, Ji A Jung, Seung Yang, Il Tae Hwang, Hae Ran Lee
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Clin Exp Pediatr. 2008;51(4):377-382. Published online April 15, 2008
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Purpose : The aim of this study is to assess the usefulness of skin test by an inactivated, 1/50 diluted solution of attenuated varicella vaccine in evaluating the immune status to varicella.
Methods : Total 41 subjects (22 males, 19 females, aged 1-32 years) were enrolled from July to August, 2005. Past medical history including varicella infection, varicella vaccination were investigated... |
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- The causative organisms of pediatric empyema in Korea
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Hye-yung Yum, Woo Kyung Kim, Jin Tak Kim, Hyun Hee Kim, Yeong Ho Rha, Yong Min Park, Myung Hyun Sohn, Kang Mo Ahn, Soo Young Lee, Su Jong Hong, Hae Ran Lee
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Clin Exp Pediatr. 2007;50(1):33-39. Published online January 15, 2007
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Department of Pediatrics , College of Medicine, Hallym University
Purpose : In spite of medical advances, empyema is a serious complication of pneumonia in children. Vaccination practices and antibiotic prescribing practices promote the change of clinical manifestations of empyema and causative organisms. So we made a nationwide clinical observation of 122 cases of empyema in children from 32 hospitals during... |
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- Review Article
- Update in asthma management
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Hae Ran Lee
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Clin Exp Pediatr. 2006;49(6):581-588. Published online June 15, 2006
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Asthma is a chronic inflammation of the airway associated with increased bronchial hyperresponsiveness that leads to recurrent episodes of cough, wheezing, breathless, chest tightness. According the recent studies, repeated airway inflammation leads to structural changes so called ‘airway remodeling’ and associated with decreased pulmonary function. Airway remodeling begins form the early stage of asthma and the early diagnosis and management... |
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- Original Article
- A Study of the Relationship between Childhood Obesity and Beverage Intake
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Ji Hyun Oh, In Keun Kwak, Seung Yang, Il Tae Hwang, Ji Ah Jung, Hae Ran Lee
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Clin Exp Pediatr. 2003;46(11):1061-1066. Published online November 15, 2003
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Purpose : The rising prevalence of childhood obesity may be due to an energy imbalance between food intake and energy expenditure. Recently, consumption of beverages in children has increased. The aim of this study is to provide useful information for the prevention and the control of childhood obesity by assessment of variable beverage consumption.
Methods : Fight hundred seventy seven children(M... |
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- A Clinical Study of Acute Colonic Diverticulitis in Children
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Jae Hoon Sim, Keum Ho Song, Yun Jung Sim, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo, Hae Ran Lee, Kwan Seop Lee
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Clin Exp Pediatr. 2003;46(11):1095-1100. Published online November 15, 2003
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Purpose : Children with acute colonic diverticulitis(ACD), can be misdiagnosed with acute appendicitis.
Methods : We reviewed 15 cases of ACD during five years, from January 1998 to June 2002 retrospectively.
Results : Most patients(80%) with ACD in children presented with right lower quadrant pain. The primary diagnosis on admission was mostly acute appendicitis(87%), and all ACD in children occurred in... |
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- Effects of Obesity on Pulmonary Functions in Children
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Seok Won Park, Hwang Min Kim, Jong Soo Kim, Jae Kuk Cha, Hae Ran Lee
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Clin Exp Pediatr. 2002;45(5):588-595. Published online May 15, 2002
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Purpose : The incidence of obesity has increased in Korea recently. Obesity leads to higher risks of hypertension, hyperlipidemia and insulin resistance. It also leads to risks of respiratory complications. This study was performed to see the effects of obesity on children's pulmonary functions and on developed bronchospasm after exercise loading according to their obesity degrees.
Methods : 257 obese... |
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- Epidemiologic and Clinical Features of
Pertussis in Children(2000. 3-2001. 3)
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Shin Yoo, Kyong Ouk Ahn, Eun Hye Park, Hyun Sang Cho, Chong Young Park, Hae Ran Lee
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Clin Exp Pediatr. 2002;45(5):603-608. Published online May 15, 2002
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Purpose : Pertussis is a highly communicable infectious disease in children with high mortality, especially in young infants. The incidence of pertussis in South Korea has decreased to about 10 cases a year in late '90s. Doubting previously reported incidences of pertussis, we designed this study to establish exact epidemiology and a diagnostic basis of pertussis.
Methods : From Mar. 2000... |
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- Case Report
- A Case of Encephalopathy Presented with Motor Aphasia and Quadriplegia Following Intrathecal Methotrexate
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Seon Woo Lee, Eun Hye Park, Hyun-Sang Cho, Jae Kook Cha, Hae Ran Lee
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Clin Exp Pediatr. 2001;44(9):1066-1069. Published online September 15, 2001
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Intrathecal administration of methotrexate(IT-MTX) has constituted the standard approach to prophylaxis
and treatment of central nevous system(CNS) leukemia. We experienced a quadriplegia
and motor aphasia in a 14-year-old boy following repeated IT-MTX for the prophylaxis of
meningeal leukemia. He was diagnosed as ALL without CNS involvement and treated by CCG-
1882 protocol. IT-MTX was administered for CNS prophylaxis. The patient began complaining of
urinary incontinence,... |
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- A Case of Apert's Syndrome with Encephalocele and
Hypogenesis of Corpus Callosum
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Min Kyoung Kwon, Ja Yun Yu, Mi Ran Kim, Kon Hee Lee, Hae Ran Lee, Kwang Nam Kim
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Clin Exp Pediatr. 2001;44(7):832-836. Published online July 15, 2001
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Apert's syndrome(acrocephalosyndactyly) is a rare congenital anomaly that is characterized by the combination of premature fusion of multiple cranial sutures primarily involving the coronal suture and severe symmetrical syndactyly of fingers and toes. Some patients of this syndrome have various abnormalities of the central nervous system. We experienced a case of Apert's syndrome with craniofacial malformations, symmetric syndactyly, occipital encephalocele... |
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- Original Article
- Bystander Effect of HSV-TK/GCV Gene
Therapy in Murine Neuroblastoma
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Eun Jung Shim, Se Ryoung Kim, Eun Hae Park, Hyun Sang Cho, Jae Kook Cha, Hae Ran Lee
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Clin Exp Pediatr. 2001;44(11):1249-1253. Published online November 15, 2001
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Purpose : To demonstrate the bystander effect in murine neuroblastoma model which transduced with HSV-TK gene in vitro and in vivo.
Methods : The LNC/TK vector was transfered in vitro into the neuro-2a cells, murine neuroblastoma cell line. Variable mixed populations of neuro-2a cells consisting of HSV-TK＋ or HSV-TK－ were plated into culture plates and treated with GCV for... |
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- Erratum
- Reference Values of Hematologic and Biochemical Parameters of Nutrition around Weaning Period
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Seung Joo Lee, Jeong Wan Seo, Jae Ock Park, Jae Hoon Shin, Hae Ran Lee, Ji Tae Chung, Hae Il Chung
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Clin Exp Pediatr. 1999;42(1):6-14. Published online January 15, 1999
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Purpose : To determine the reference values of hematologic and biochemical parameters of nutrition around the weaning period.
Methods : From February 1996 to March 1997, several nutritional laboratory values were evaluated in 130 healthy babies and 120 inpatients in the recovery stage of acute illness at six general hospitals.
Results : Reference values in 9-month-old healthy babies(range : 6-12 months) were... |
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- Original Article
- A Clinical Study on Acute Lower Respiratory Tract Infections by Adenovirus in Children
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Ui Chong Chong, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Han Sung Kim, Kyu Man Lee
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Clin Exp Pediatr. 1998;41(8):1070-1077. Published online August 15, 1998
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Purpose : This study was performed to characterize the epidemiologic and clinical features of acute adenoviral lower respiratory tract infections.
Methods : Culture and indirect immunofluorescence for adenovirus was done with nasopharyngeal aspirates from patients with acute lower respiratory tract infections from April to September, 1996. Cultured virus was serotyped for type 3, 4, and 7a by neutralization test, and medical... |
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- A Clinical Analysis on Acute Lower Respiratory Tract Infections in Children Caused by Influenza Virus in Children
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Kiehl Hyung Lee, Woo Kyung Kim, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Kyu Man Lee
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Clin Exp Pediatr. 1998;41(12):1623-1631. Published online December 15, 1998
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Purpose : Although annual epidemics occur, there are only a few clinical studies on influenza in Korea. We evaluated the epidemic and clinical features of acute lower respiratory tract infections in children by influenza virus.
Methods : From Feb., 1995 to July, 1997, influenza virus isolations and clinical review were performed on hospitalized children with acute lower respiratory tract infections at... |
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- Epidemiologic and Clinical Feature of Acute Lower Respiratory Tract Infections by Respiratory Syncytial Virus and Parainfluenza Virus in Children
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Jeoung Jin Lee, Hyeon Seon Park, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Woo Kap Chung, Kyu Man Lee
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Clin Exp Pediatr. 1997;40(8):1071-1080. Published online August 15, 1997
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Purpose : This is to analyze epidemic and clinical features of acute respiratory tract infections(ALRTI) by respiratory syncytial virus(RSV) and parainfluenza virus(PIV), which are considered to be the major respiratory pathogens in children.
Methods : Nasopharyngeal aspirates were collected from 515 patients with ALRTI hospitalized at Hangang Sacred Heart Hospital between Apr. ’94 and Oct. ’96. Nasopharyngeal aspirates were inoculated to... |
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- Erratum
- A Survey on the Factors Related to the Failure of Breast-feeding
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Seung Joo Lee, Jeong Wan Seo, Jae Ock Park, Jae Hoon Shin, Hae Ran Lee, Ji Tae Chung, Hae II Chung
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Clin Exp Pediatr. 1997;40(10):1336-1346. Published online October 15, 1997
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Objective : The breast-feeding rate has decreased in Korea despite of the active
encouraging effort of breast-feeding for the last 10 years. So we investigated the factors
that are related to breast-feeding failure.
Method : 1807 specific questionares of mothers who visited the six university hospitals
in Seoul from October 1993 to December 1995 were analysed by ANOVA and multiple
logistic regression using SAS program.
Results... |
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- Case Report
- Familial Erythrophagocytic Lymphohistiocytosis in Siblings
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Eun Sook Lee, Ji Eun Choi, Dug Ha Kim, Hae Ran Lee, Chong Young Park
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Clin Exp Pediatr. 1995;38(3):428-434. Published online March 15, 1995
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Familial erythrophagocytic lymphohistiocytosis(FEL) is an uncommon disorder characterized by multi-organ infiltration with phagocytic histiocytes and macrophages. It is a familial discorder presenting during infancy or young childhood with fever, hepartosplenomegaly, pancytopenia, bleeding diathesis, hypertriglyceridemia and neurologic manifestations. The course of the disease is extremely lethal and diagnosis of the disease during lifetime is very difficult. Exact diagnosis can only be... |
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- Original Article
- Role of Adenovirus in Diarrheal Children
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Gyung Ok Yu, Young Bae Moon, Dong Rak Choi, Duk Ha Kim, Hae Ran Lee, Chong Young Park, Hee Jung Kang, Kyu Man Lee
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Clin Exp Pediatr. 1994;37(2):205-211. Published online February 15, 1994
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In order to investigate the role of adenovirus in diarrheal children, we evaluated 907 children with diarrhea and 193 children without diarrhea for a 22-month. Stools were tested for group A rotavirus antigen and for adenovirus types 40/41 (Ad 40/41) by using ELISA, cell technique and indirect immunofluorescent method. Adenovirus was detected in 10.1% of the diarrheal children and 3.1%... |
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- A Survey on the Present Status of Weaning
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Seung Joo Lee, Jae Ok Park, Chang Sung Sohn, Hae Ran Lee, Jae Hoon Shin, Hae Il Chung, Seung Il Kim
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Clin Exp Pediatr. 1994;37(12):1643-1656. Published online December 15, 1994
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Purpose : To add proper solid food during the ideal weaning period is very important to supply adequate nutrition for the rapid growt and to achieve proper feeding habits in later infancy. We tried to survey the problems in weaning in Korea.
Methods : The Present status of infant weaning was sutneyed 6 university hospital in Seoul and 4 rural goverment... |
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- Case Report
- A Case of Ritter's Disease
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Young Kul Lee, Eun Mi Kim, Dong Rak Choi, Hae Ran Lee, Chong Young Park
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Clin Exp Pediatr. 1992;35(6):840-844. Published online June 15, 1992
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Ritter's disease, or staphylococcal scalded skin syndrome, is a form of skin disease due to the exfoliative toxin, exfoliatin, produced by various species of staphylococci and is characterized by generalized bullae formation and exfoliation.
The authors experienced a case of Ritter's disease in an 8 day-old newborn who had generalized bullae and skin exfoliation. Unfortunately, the patient expired on the 13th... |
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- Original Article
- Hepaplastin Test for Screen of Vitamin K Deficiency in Term and Preterm Neonates
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Eun Mi Kim, Gyung Og Yu, Dong Rak Choi, Chong Young Park, Hae Ran Lee, Choon Myung Ro
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Clin Exp Pediatr. 1992;35(5):614-620. Published online May 15, 1992
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To screen vitamin K deficiency in term and preterm neonates, the authors conducted Hepaplastin test based on 40 term and 40 preterm neonates who were delivered at Han Gang Sacred Heart Hospital. Also we compared Hepaplastin activity of term neonates with that of preterm neonates. 0.5mg or 1mg of vitamin K1 was injected intramuscularly immediately after birth according to the... |
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- A clinical study on meconium-stained babies.
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Cheol Ki Min, Sung Suk Bang, Chong Young Park, Hae Ran Lee, Choon Myung Ro
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Clin Exp Pediatr. 1991;34(1):24-30. Published online January 31, 1991
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Among a total of 667 newborns delivered at Han Gang Sacred Heart Hospital from January 1988
to July 1989, a clinical study was done regarding meconium-stained babies.
The results were summarized as follows:
1) The incidence of meconium staining was 25.9% (173 babies) and there was no difference of
frequency in sex.
2) The higher the birth weigt and the gestational age, the higher the incidence of... |
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- Caudal Regression Syndrome Associated with Potter Syndrome.
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Hyun Joo Jeong, Sung Sook Bang, Hae Ran Lee, Choon Myung Ro, Yeon Lim Suh
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Clin Exp Pediatr. 1989;32(10):1448-1454. Published online October 31, 1989
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Caudal egression syndrome is a term applied to a syndrome comprising complete or partial agenesis
of sacrum and coccyx, often associated with malformation of the lower extremities, congenital heart
disease, urologic abnormalities and malformation of the upper extremities. The primary defect may
occur in the mid-posterior axis mesoderm of the embryo prior to the 4th week of development,
resulting in other defects of the... |
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