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Original Article
Clinical Observation of urinary Tract Anomalies
In Hee Jung, Hong Jin Lee, Sang Joo Han, Won Il Park, Kyung Ja Lee
Clin Exp Pediatr. 1994;37(8):1092-1096.   Published online August 15, 1994
Urinary tract anomaly is the most common anomaly in childhood. We reviewed medical records of 45 patients who were confirmed urinary tract anomalies on radiologic studies as Chuncheon Sacred Hospital, from Dec. 1984 to Sep. 1992. We analyzed incidence and clinical characteristics of urinary tract anomalies. The results obtained were as follows: 1) The age distrtibution were: 17 cases (37.8%) under...
Protective Effect of Breast Feeding for Infection
Jin Kyung Jung, In Nam Kang, Dong Ju Sin, Doo Bong Lee
Clin Exp Pediatr. 1994;37(7):906-912.   Published online July 15, 1994
A Comparative study was retrospectively performed with 374 infants in order to find protective effect of breast feeding for infection. This study shows that breast feeding protect infant against gastrointestinal and respiratory infcttion. Breast feeding offers advantage by reducting gastraintestinal and respiratory infection when they should maintain breast feeding for at least three months. 1) First year morbidity increased with extent of artificial...
Primary Cutaneous Aspergillosis in Leukemic Children
Jin Young Park, Mee Ran Kim, Hee Young Shin, Hoan Jong Lee, Hyo Seop Ahn, Je Guen Chi
Clin Exp Pediatr. 1994;37(4):520-526.   Published online April 15, 1994
Primary cutaneous aspergillosis is rare. In this report we describe primary skin infection by Aspergillus in 9 children with leukemia. The skin lesion was characterized clinically by erythematous macule and papule associated with pain and itching, followed by a rapid progression to ulcer and central black eschars with raised erythematous border at the site of venipuncture, insertion of intravenous cannula,...
Coxiella Burnetii Infection In Patients With Various Diseases
Kyo Sun Kim, Won Young Lee
Clin Exp Pediatr. 1994;37(3):356-367.   Published online March 15, 1994
Coxiella burnetii(C. burneii) was first recognzed as the agent of Q fever in 1937. Q fever is an acute self-limited febrile illness. However, it manifests with several clinical symptoms depending upon the organs that are involved. The association of C. burnetii with human neoplasia has been rarely reported. We prospectively studied the 55 patients with fever of unknown origin, pneumonia, hepatos-plenomegaly,...
Renal Scarring in Relation to Vesicoureternal Reflux in Uriary Tract Infection
Kwang Sun Han, Dong Jin Choi, Sung Ho Cha, Byoung Soo Cho, Young Tae Ko, Sun Wha Lee
Clin Exp Pediatr. 1993;36(10):1402-1406.   Published online October 15, 1993
The vesicoureteral reflux (VUR) is frequently found among the patients with urinary tract infection (UIT) and some patients with VUR progress to reflux nephropathy. The presence of scarring at UIT is an important determinant in the selection of those at risk of progressive damage. 99m Technetium dimercaptosuccinic acid (99mTc-DMSA) is a renal scanning agent provides a good quality of renal image...
Case Report
A Case of Wiskott-Aldrich Syndrome
Dong Un Kim, Seung Hoon Han, Jin Han Kang, Joon Sung Lee
Clin Exp Pediatr. 1993;36(3):439-446.   Published online March 15, 1993
Wiskott-Aldrich syndrome s an X-linked combined immunodeficency disorder characterzed by severely decreased number of platelets which are small in size, eczema resembling atopic dermatitis and recurrent infection. The serum of the patient contains elevated concentrations of IgA and IgE, whereas the IgG level is usually normal and IgM level is deecreased. The patient also shows skin test anergy and progressive...
Original Article
Childhood Infection-associated Hypocalcemia
Mi Reong Kim, Seoung Hwan Kim, Hee-Shang Youn, Chong-Hwa Kim
Clin Exp Pediatr. 1993;36(2):223-231.   Published online February 15, 1993
The causes of hypocalcemia in patients suffering from severe infection including sepsis are largely uncertain. So we measured serum albumin, total protein, cholesterol, PTH, and calcitonin of the infection-associated hypocalcemic chlidren and compared with those of normocalcemic children department of pediatrics of Gyeongsang National University Hospital. Hypocalcemic patients were compared to the decreased amount of serum albumin in the hypocalcemic...
Follow up Study of Urinary Tract Infection Associated with Vesicoureteral Reflux
Kyung Hee Kim, Young Jin Hong, Soon Wha Kim, Don Hee Ahn
Clin Exp Pediatr. 1992;35(12):1713-1721.   Published online December 15, 1992
The authors studied 25 cases with urinary tract infection associated with vesicoureteral reflux who were admitted to department of pediatrics, National Medical Center. The patients were managed medically or surgically and followed up. The results were summarized as follows; 1) There were no difference in age and sex distributions of the 25 cases with vesicoureteral reflux. 2) The degree of reflux classified by International...
Screening of urinary Tract Infection in High-Risk Neonates
Hyeon Joo Choi, Seung Joo Lee
Clin Exp Pediatr. 1992;35(12):1683-1679.   Published online December 15, 1992
Since the urinary tract infection (UTI) in neonates is often associated with major urologic anomalies, early diagnosis is essential. In the screening of UTI by urine bag, contamination is a commonly encountered problem. Suprapubic bladder puncture has therefore been recommended as the best method to confirm UTI. The purpose of this study is to assess the frequency and characteristics of...
Clinical Application of APR score in the Detection of Neonatal Infections; Comparison of Fullterm and Premature
Sei-Joon Ko, Sang Mi Ha, Mi Kyeung Lee, Soon Il Lee
Clin Exp Pediatr. 1992;35(12):1674-1682.   Published online December 15, 1992
We measured APR scores for the 100 newborns of having suspected systemic infection prospectively, and evaluated the clinical significance of the results of the APR scores; in fullterm babies and in premature babies. The percentage of high APR score group (≥2) was 81% in fullterm and 66% in premature babies. When the results of the APR scores were compared to the...
Clinical and Epidemiologic Features of Respiratory Syncytial Virus Infection
Hoan Jong Lee, Seong Hee Jang
Clin Exp Pediatr. 1992;35(10):1389-1401.   Published online October 15, 1992
Although lower respiratory tract infection is a major cause of childhood morbidity in Korea and respiratory viruses are presumed to be important pathogens, there have been few studies available. We diagnosed RSV infection by virus isolation and immunofluorescence in children with lower respiratory tract infection, seen at Seoul National University Children's Hospital from Nov. 1990 to Jul. 1991. The results were...
Case Report
Acquired Persistent Cytomegalovirus Infection : An Association with Common Variable Immunodeficiency
Min Hyea Kim, Young Mi Hong, Sung Joo Lee, Je Geun Chi, Dong Soo Kim
Clin Exp Pediatr. 1992;35(9):1272-1279.   Published online September 15, 1992
Acquired persistent cytomegalovirus infection was diagnosed by anti CMV antibody and lymph node biopsy and persisted in a 3-year-old boy with recurrent episode of high fever, lymphadenopathy hepatosplenomegaly and pneumonia. Initial immunologic abnormalities including low serum IgG, high IgM decreased T4 and T4/T8 ratio finally progressed to immunologic paralysis which was compatible to common variable immunodeficiency. This is the first case which...
Transfusion-Acquired Cytomegalovirus Infections in Two Premature Infants
Dong Wook Kim, Kyung Un No, Mi Jung Kim, Soon Mee Park, Hee Sup Kim, Young Pyo Chang, Hoan Jong Lee, Jung-Hwan Choi, Chong Ku Yun, Je Geun Chi
Clin Exp Pediatr. 1992;35(8):1141-1147.   Published online August 15, 1992
Transfusion-acquired perinatal cytomegalovirus (CMV) infection can cause significant morbidity and mortality, particularly in premature infants with a birth wight of less than 1,500 gm. This recognizable syndrome consisted of deterioration of respiratory function, hepatosplenogaly, unusual gray pallor with disturbing septic appearance, lymphocytosis, thrombocytopenia and hemolytic anemia. We experienced transfusion-acquired CMV infections in 2 premature infants with a birth weight of...
Original Article
Clinical Study of Group B Streptococcal Infection in Infants Less Than Two Months of Age
Hee Jeong Ahn, Ji Yeon Lim, Sung Hee Oh, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1992;35(1):17-25.   Published online January 15, 1992
Since 1970, the group B streptococcus has become significant cause of neonatal septicemia and/or meningitis, in recent years the group B streptococcus and E.coli are most common etiologic agent of septicemia and/or meningitis in infants less than two months of age. We have analized 8 cases of group B streptococcal infection who admitted to the department of Pediatrics, Hanyang University...
Congenital cytomegalovirus infection: incidence and clinical outcome.
Young Mo Sohn, Kook In Park, Chul Lee, Dong Kwan Han, Won Young Lee
Clin Exp Pediatr. 1991;34(10):1365-1372.   Published online October 31, 1991
In order to assess the rate of congenital cytomegalovirus (CMV) infection in newborns, CMV IgG antibody was studies at about 37.5 weeks gestation in 309 mothers and a positive rate of 96.4% was obtained. Virus culture for CMV from urine of 514 neonates less than 1 week after birth resulted in CMV growth in 6 neonates showing a 1.2% congenital infection rate. In...
A case of nephrogenic diabetes insipidus due to vesicoureteral reflux.
Yong Bae Suh, Jong Yul Jeon, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1991;34(9):1299-1304.   Published online September 30, 1991
Nephrogenic diabetes insipidus is a disorder characterized by polydipsia and polyuria resulting from failure of the renal tubules and collecting ducts to respond to antidiuretic hormone despite elevated blood levels of antidiuretic hormone. We experienced a case of nephrogenic diabetes insipidus in 13 months-old girl probably secondary to vesicoureteral reflux grade IV. The clinical manifestations were extreme thirst, polydipsia and polyuria. Family history was nonspecific and...
The diagnostic significance of APR score in early detection of neonatal bacterial infection.
Ki Won Park, Kyeong Choi, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1991;34(9):1223-1230.   Published online September 30, 1991
An accurate and rapid diagnostic test is essential in the management of bacterial infection in neonates because they lack specific symptoms and the bacterial infections in neonates tends to have rapid progression and poor prognosis. As for the method, APR (acute phase reactants), a score measuring C-reactive protein (CRP), 상racid glycoprotein (이-AG) and Haptoglobin (Hp) by latex agglutination seems to be one of promising methods. In...
A case of pancytopenia associated with mycoplasmal pneumonia.
Young Mee Yoo, Beom Soo Park, In Sang Jeon, Hee Young Shin, Hyo Seop Ahn, Se Jung Sohn
Clin Exp Pediatr. 1991;34(6):826-831.   Published online June 30, 1991
Mycoplasma pneumoniae infection is manifestated as pneumonia and extra-pulmonary symptoms such as hematologic, neurologic, gastrointestinal, musculoskeletal, dermatologic and cardiac manifes- tations. Among the hematologic changes, hemolytic anemia is most frequently seen. Throm- bocytopenic purpura, lymphocytosis or rarely lymphopenia, elevated erythrocyte sedimentation rate, positive direct Coombs test, reticulocytosis and DIC are known hematologic features. This 12 years old female patient was presented with pneumonia and pancytopenia....
A case of hyperimmunoglobulin E syndrome.
Myeong Cheol Shinn, Sung Dong Choi, Byung Gyu Suh, Jin Han Kang, Joon Sung Lee
Clin Exp Pediatr. 1991;34(2):292-298.   Published online February 28, 1991
The hyperimmunoglobulin E syndrome is a primary immunodeficiency disorder characterized by serious recurrent bacterial infections of the skin and respiratory system in early life, and markedly elevated serum IgE level. These recurrent infections are generally subcutaneous abscesses caused by Staphylococcus aureus. Also, additional characteristrics of this syndrome include coarse facial appearance, chronic pruritic dermatitis and eosinophilia. The baisic immunologic defect mechanism in hyperimmunoglobulin E syndrome is...
A clinical and bacteriologic study of infants and children with urinary tract infection.
Jae In Roh, Yeong Su Kwon, Hung Kun Oh, Jin Hee Jeong, Man Chul Ha, Jin Yeong Jeong
Clin Exp Pediatr. 1991;34(1):57-65.   Published online January 31, 1991
Clinical, Bacteriologic and radiologic studies were performed in 321 infants and childen with urinary Tract Infection who were diagnosed at Department of pediatrics, Haesung Hospital from Jan. 1984 to Dec. 1988. The results were summarized as follows: 1) The incidence of urinary tract infection was highest in children below the age of one year, the rate then decreased with age. Among the total 321 cases,...
Congenital Cytomegalovirus infection.
Kang Woo park, Ho Seek Ahn, Eui Bon Koo, Sung Won Kim, Kil Hyun Kim
Clin Exp Pediatr. 1990;33(9):1271-1275.   Published online September 30, 1990
We report a case of congenital cytomegalovirus infection that was associated with microcephaly, hydrocephalus and periventricular calcification. The male baby was born after 39wks gestation to 28 year-old mother who had no prenatel problem except for active pulmonary tuberculosis and pre- mature rupture of membrain. Hydrocephalus was recognized by antenatal ultrasonography at 8 weeks of geststional age and microcephaly was noted at birth. This enable...
Relationship between anaphylactoid purpura and Beta-Hemolytic Streptococcal Infection.
Ji Eun Lee, Young Sook Kang, Joon Sik Kim, Sung Ho Kim, Chin Moo Kang
Clin Exp Pediatr. 1990;33(9):1231-1236.   Published online September 30, 1990
Relationship between anaphylactoid purpura and beta-hemolytic streptococcal infection was obser- ved and analyzed through clinical manifestation and labortory findings in 146 cases of allergic purpura, hospitalized at Dongsan hospital, Keimyung University during the period from January, 1981 to May, 1987. The following results were obtained. 1) The age distribution of anaphylactoid purpura showed a peak incidence between 2 to 7 years of age and male preponderance was...
Comparison of the 3-Imaging Procedures (IVP,VCUG & USG) on Children with Urinary Tract Infection.
Min Hee Yeo, Won Yeob Kim, Jee Sung Kim, Sang Geel Lee, Im Ju Kang
Clin Exp Pediatr. 1990;33(3):332-340.   Published online March 31, 1990
This study was performed in 106 childrens with urinary tract infection who were admitted to Pediatric Department of Fatima Hospital during 2 1/2 years period from January 1986 to June 1988. Each patient was evaluated in three imaging procedures: intravenous pyelography (IVP), voiding cystourethrography (VCUG) and ultrasonography (USG). 1) Of 106 cases, 59 cases (55.7%) were normal on the three imaging procedures (IVP, VCUG, USG), whereas...
A Study on Anemia of Acute Infectious Disease in Children.
Hae Won Lee, Young Mi Hong, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1990;33(1):75-80.   Published online January 31, 1990
The anemia of acute infectious disease has come to attention recently, since iron deficiency anemia has decreased. We screened for anemia in children admitted to Ewha Womans University Hospital due to acute infectious disease between January 1, 1986 and July 31, 1988, and studied the incidence and characteristics of anemia in acute infectious diseases. The result were as follows: 1) The incidence of anemia in acute...
A Clinical Study of Infants and Children with Urinary Tract Infection.
Hyoung Doo Lee, Chan Yung Kim
Clin Exp Pediatr. 1989;32(12):1706-1714.   Published online December 31, 1989
Clinical, bacteriologic and radiologic studies were performed in 63 infants and children with urinary tract infection who were admitted to Department of Padiatrics, Pusan National University Hospital from March 1982 to February 1988. The results were summarized as follows: 1) UTI was more prevalent in infancy and early childhood (71.4%). Sex distribution was similar in all age group, and male was more prevalent in infancy and...
Asymptomatic human rotavirus infections during infancy and preschool period.
Hye Lim Jung, Byoung Hoon Yoo, Tae Sub Shim
Clin Exp Pediatr. 1989;32(11):1482-1488.   Published online November 30, 1989
Asymptomatic human rotavirus (HRV) infection rate was studied by comparing the rate of HRV excretion in diarrhea cases with that in nondiarhea group of children under preschool age. HRV antigen in stool was detected by enzyme-linked immunosorbent assay (ELISA) from children under 6 years of age who were admitted to Pediatric Department of Chung-Ang University Medical Center from November 1988 to mid-April 1989. 1) HRV antigen...
A study of neonatal cholestasis and cytomegalovirus infection.
Moon A Kim, Ki Sup Chung
Clin Exp Pediatr. 1989;32(11):1474-1481.   Published online November 30, 1989
A clinical assessment of 25 patients with neonatal cholestasis caused by cytomegalovirus infection who were admitted to the Department of Pediatrics, Yonsei University College of Medicine from January 1983 to July 1988 was performed. The results were as follows: 1) The patients with neonatal cholestasis caused by cytomegalovirus infection were 19% of the total patients with neonatal cholestasis from January 1983 to July 1988 and were...
Urinary Tract Infection Caused by Escherichia coli.
Sung Oh Kim, Sun Yang Hong, Woo Gill Lee
Clin Exp Pediatr. 1989;32(7):972-977.   Published online July 31, 1989
Among 223 cases who were admitted to the Department of Pediatrics, Hanyang University Hospital from January 1980 to December 1987 under the diagnosis of Urinary Tract Infection(UTI), 132 cases of E. coli UTI were compared with 91 cases of non-E. coli UTI by age, sex distribution, clinical manifestation, laboratory results and clinical course. The results obtained were as follows: 1. There were no significant differences of...
Radiologic Evaluation About Urinary Tract Infection In Children.
Soon Wha Kim, Byung Rai Cho, Don Hee Ahn, Keun Chan Sohn, Chong Hyun Yoon
Clin Exp Pediatr. 1989;32(6):797-803.   Published online June 30, 1989
There had been total 165 cases of urinary tract infection who had been admitted to the ward of pediatrics, National Medical Center from ]an. 1986 to Sept. 1987. Among these, 80 cases had indication of radiologic evaluation; they were the first-documented urinary tract infection in male patients, the first documented urinary tract infection in female patients younger than 6 years of age,...
Infections in Childhood Leukemia.
Choong Won Lee, Young Sik Kim, Byung Kyu Park, Soon Ki Kim, Il Soo Ha, Hoan Jong Lee, Hyo Seop Ahn
Clin Exp Pediatr. 1989;32(5):659-664.   Published online May 31, 1989
A retrospective study was performed on twenty-nine children, who had experienced infection one or more times, among the thirty-eight children diagnosed as leukemia at the Department of Pediatrics, Seoul National University Hospital, between January, 1984 and June, 1985, and followed up for more than three years. The results were as follows; 1) The age of patients ranged from I year 5 months to 14 years...
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