Journal of the Korean Pediatric Society 1989;32(5):659-664.
Published online May 31, 1989.
Infections in Childhood Leukemia.
Choong Won Lee, Young Sik Kim, Byung Kyu Park, Soon Ki Kim, Il Soo Ha, Hoan Jong Lee, Hyo Seop Ahn
Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
소아백혈병에서의 감염에 대한 연구
이충원, 김영식, 박병규, 김순기, 하일수, 이환종, 안효섭
서울대학교 의과대학 소아과학교실
Received: 7 November 1988   • Accepted: 7 November 1988
A retrospective study was performed on twenty-nine children, who had experienced infection one or more times, among the thirty-eight children diagnosed as leukemia at the Department of Pediatrics, Seoul National University Hospital, between January, 1984 and June, 1985, and followed up for more than three years. The results were as follows; 1) The age of patients ranged from I year 5 months to 14 years 7 months and the ratio of male to female was 2.2:1. 2) Of 29 patients, 39 cases of infection occurred and mean duration of infection were 9.6 days. Twenty-six percent occurred during induction, 67% in remission state, and 7% during reinduction. 3) Pneumonia was the most common type of infection, all of which developed during remission period. 4) Sixty-seven percent of total infection accompanied with febrile episode and 38% occurred during granulocytopenic period. 5) The pathogen of infection was confirmed in 13 cases (bacteria 7, virus 5, fungus 1). 6) Of 30 cases treated with antibiotics, 24 cases improved with cephalosporin and aminoglycoside. Six cases expired due to sepsis (3 cases), pneumonia (2 cases) and blast crisis (1 case).
Key Words: Childhood leukemia, Infection

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