| Infections in Childhood Leukemia. |
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Choong Won Lee, Young Sik Kim, Byung Kyu Park, Soon Ki Kim, Il Soo Ha, Hoan Jong Lee, Hyo Seop Ahn |
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Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea |
| 소아백혈병에서의 감염에 대한 연구 |
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이충원, 김영식, 박병규, 김순기, 하일수, 이환종, 안효섭 |
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서울대학교 의과대학 소아과학교실 |
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Received: 7 November 1988 • Accepted: 7 November 1988 |
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| Abstract |
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A retrospective study was performed on twenty-nine children, who had experienced infection one
or more times, among the thirty-eight children diagnosed as leukemia at the Department of
Pediatrics, Seoul National University Hospital, between January, 1984 and June, 1985, and followed
up for more than three years.
The results were as follows;
1) The age of patients ranged from I year 5 months to 14 years 7 months and the ratio of male to
female was 2.2:1.
2) Of 29 patients, 39 cases of infection occurred and mean duration of infection were 9.6 days.
Twenty-six percent occurred during induction, 67% in remission state, and 7% during reinduction.
3) Pneumonia was the most common type of infection, all of which developed during remission
period.
4) Sixty-seven percent of total infection accompanied with febrile episode and 38% occurred during
granulocytopenic period.
5) The pathogen of infection was confirmed in 13 cases (bacteria 7, virus 5, fungus 1).
6) Of 30 cases treated with antibiotics, 24 cases improved with cephalosporin and aminoglycoside.
Six cases expired due to sepsis (3 cases), pneumonia (2 cases) and blast crisis (1 case). |
| Key Words:
Childhood leukemia, Infection |
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