Journal of the Korean Pediatric Society 1993;36(10):1402-1406.
Published online October 15, 1993.
Renal Scarring in Relation to Vesicoureternal Reflux in Uriary Tract Infection
Kwang Sun Han1, Dong Jin Choi1, Sung Ho Cha1, Byoung Soo Cho1, Young Tae Ko2, Sun Wha Lee2
1Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
2Department of Diagnostic Radiology, College of Medicine, Kyung Hee University, Seoul, Korea
소아 요로감염에 있어서 방관요관역류와 신반흔과의 관계
한광선1, 최동진1, 차성호1, 조병수1, 고영태2, 이선화2
1경희대학교 의과대학 소아과학교실
2경희대학교 의과대학 진단방사선학교실
The vesicoureteral reflux (VUR) is frequently found among the patients with urinary tract infection (UIT) and some patients with VUR progress to reflux nephropathy. The presence of scarring at UIT is an important determinant in the selection of those at risk of progressive damage. 99m Technetium dimercaptosuccinic acid (99mTc-DMSA) is a renal scanning agent provides a good quality of renal image as a result of preferential cortical accumulation. 99mTc-DMSA scan and VCUG were performed in 133 patients diagnosed UTI at pediatric department of Kyung Hee University, College of Medicine from May, 1990 to May, 1992 The results were as follows: 1) VUR was seen in 27 children among 133 patients with UTI. The incidence was 20.3%. Under 1 year of age. Male to female ratio was higher incidence of VUR. 2) Incidence of renal scarring was higher in patients with VUR than those of without VUR. 3) Grading of VUR in relation to age, the older the age, the lower the grade. 4) There is no correlation between renal scarring and grades of VUR. 5) In distribution of renal scarring, it was found to have tendency to develop at upper polar area, there was diffuse and multiple in patients with VUR. In conclusion, the incidence of renal scarring was related to the age of onset, duration of UTI and the severity of the VUR and 99mTc-DMSA scan is mandatory in patient with UTI even without VUR in order to detect early phase of renal scarring.
Key Words: Urinary tract infection, Vesicoureteral reflux, DMSA scan.

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