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Original Article
A Case of Addison's Disease.
In Hoon Lee, H. D. Lee, Hee Ju Jeon, Chan Yung Kim
Clin Exp Pediatr. 1988;31(12):1689-1695.   Published online December 31, 1988
A 9-year-old girl with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was transferee! to our hospital because of darkish brown pigmentation of whole body and generalized weakness which had misunderstood cyanotic heart disease. On physical examination, she was poorly nourished and below 10 percentile in weight and height. Skin and mucous membrane were diffusely darkish brown,...
Two Cases of Chronic Bronchitis in Children Who Showed Perfusion Defects at the Base of Lung.
Hyeon Soo Lee, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(12):1663-1668.   Published online December 31, 1988
We experienced two cases of chronic bronchitis in 9 4/12 year female & 10 year old male who were admitted at department of Pediatrics, College of Medicine, Yonsei University. In which all laboratory findings including chest X-ray were normal, but on the scitiscan perfusion defects were noted at the base of lung and clinically improved accociated with disappearance of perfusion defects ossurred after treatment. The...
A Case of Wilson Disease.
Cheol Soo Dan, Sang Hoon Lee, Woo Yeong Chung, Soon Yong Lee, Jong Eun Joo, Hye Jae Cho
Clin Exp Pediatr. 1988;31(11):1502-1508.   Published online November 30, 1988
We have experienced a case of Wilson disease manifesting chronic hepatitis. The patient, 10-year-old boy, has shown elevated SGOT and SGPT levels since 5 years ago, but no other specific symptoms of Wilson disease. His younger sister died of fulminant hepatitis (absence of hepatitis A or B markers) at the age of eight. The diagnosis was based on the characteristic laboratory data and the...
Non-specific Immunotherapy with Histamine-Gammalobulin Preparations in Chronic Respiratory Group Patients and Non-atopic Asthmatic Children.
Byeung Ju Jeoung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(10):1308-1314.   Published online October 31, 1988
We evaluated the therapeutic effect of non-specific immunotherapy with Histamine- gammahlobulin in 60 patients. Among them 22 patients were chronic respiratory group patients who were under 2 years of age and suffered from frequent respiratory tract infections, and 38 patients were as follows: 1) Excluding the patients who received 9 weeks therapy for the test period, the mean duration of Histamine-gammaglobulin therapy in the chronic respiratory...
Goiter in Children.
Young Wan Kim, Duk Hi Kim, Byeung Ju Jeoung
Clin Exp Pediatr. 1988;31(8):1028-1036.   Published online August 31, 1988
We studied 197 cases of patients with goiter who visited Department of Pediatrics, Yonsei University College of Medicine from January 1980 to June 1987. For each patient, serum T4, free T4, T3, TSH, antithyroid antibody, and antimicrosomal antibody were analyzed, thyroid scan was performed, and radioiodine uptake was measured. Following results were obtained: 1) Male to female ratio of 197 cases of goiter was 1:7.5, predominent...
Chronic Renal Failure in Children.
Kyung Ok Lee, Young Ho Ahn, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1988;31(6):738-746.   Published online June 30, 1988
Present study was undertaken to see the various clinicopathologic findings and outcome on 18 children with chronic renal failure, who had been admitted to the Pediatric department of Kyungpook National University Hospital from 1978 to 1986. And the following results were obtained. Male to female ratio was 5 to 4 and in 15 out of 18 cases, renal failure developed after 5 years of...
Clinical Observation on Hemodialysis in Children with Chronic Renal Failure.
Hae Il Cheong, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1988;31(5):590-596.   Published online May 31, 1988
There had been total 21 children with end stage renal disease in whom hemodialysis was done in the pediatric dialysis unit of Seoul National University Children’s Hospital during the period from 1986. 3. 31 to 1987. 11. 30. And we took a retrospective review of their clinical data, and the results were as follows 1) Primary glomerular disease, H enoch-Schdnlein nephritis, and reflux nephropathy were...
A Case of Juvenile Chronic Myelogenous Leukemia Associated with Juvenile Xanthogranuloma.
Eun Yong Lee, Jin Tae Kim, Young Sook Hong, Soon Kyun Kim, Hyun Keum Lee
Clin Exp Pediatr. 1987;30(11):1299-1304.   Published online November 30, 1987
We experienced a case of juvenile chronic myelogenous leukemia associated with juvenile xanthogranuloma and neurofibromatosis. This 1-year 6-month-old male patient had multipe cafg-au-lait spots, numerous nontender, yellowish, dome-shaped papules and nodules, hepatosplenomegaly, and pneumonia. Hematologic & bone marrow examinations, chromosomal study, and skin biopsy were performed for diagnosis. A brief review of the related literatures was added.
A Clinico-Epidemilological Study of 55 Cases of Chidhood Idiopathic Thrombocytopenic Purpura.
Won Ho Kang, Myung Hee Kook, Yong Sang Yoo, Jae Suk Ma, Tai Ju Hwang
Clin Exp Pediatr. 1987;30(11):1207-1212.   Published online November 30, 1987
Fifty-five children with idiopathic thrombocytopenic purpura (ITP) were admitted to the Department of pediatrics, Chonnam University Hospital during 6 years and 5 months from January 1980 to May 1986. We Compared clinical pictures and effects of steroids and platelet concentrates on acute and chronic ITP. No significant sexual predominance was found in total patients with ITP, but also between acute and chronic types,...
Chronic Hepatitis B in Children.
Don Gyu Yang, Jong Kyun Lee, Pyung Kil Kim, Chang Ho Hong, Chul Lee
Clin Exp Pediatr. 1987;30(10):1115-1123.   Published online October 31, 1987
We reviewed 19 cases of chronic hepatitis B confirmed by liver biopsy during the 3 years and 5months from March 1983 to July 1986 at Young Dong Severance Hospital. The following results were obtained: 1) There were 16 boys and 3 girls with ages ranging from 7 months to 14 years old (mean+S.D.; 6.5 ±0.9 years). 2) There were 2 cases (10.5%) of chronic persistent...
Clinical Observation on Splenectomized Children.
Mi Ryung Um, Jae Won Song, Yong Yull Koh, Jeong Kee Seo, Hyo Seop Ahn, Chang Yee Hong, Kwi Won Park
Clin Exp Pediatr. 1987;30(5):511-517.   Published online May 31, 1987
A clinical study was performed on 26 cases of splenectomized children who had been seen at the Department of Pediatrics, Seoul National University Hospital, during the period of 7 years 7 months from January 1978 to July 1985. The results were as follows: 1) Primary diseases were hereditary spherocytosis (8 cases), Hodgkin disease for staging laparotomy (8 cases), ...
Juvenile Chronic Lymphocytic Thyroiditis.
Duk Hi Kim
Clin Exp Pediatr. 1987;30(1):71-79.   Published online January 31, 1987
A diagnosis of chronic lymphocytic thyroiditis(CLT) was made in 90 children & adolescents according to Fisher’s criteria. The age of the group ranged between 4 years & 16 years. On the basis of serum T4, T3 & TSH, three groups of patients were distinguished at the time of diagnosis.: euthyroid group (n=49), hyperthyroid group (n=7), hypothyroid group (n=34), where three subgroups were classified;...
A Clinical and Pathologic Study on Chronic Hepatitis in Infancy and Childhood.
Ki Sub Jung, Chan Ill Park
Clin Exp Pediatr. 1987;30(1):35-44.   Published online January 31, 1987
A clinical and pathologic study was undertaken on 46 cases of chronic hepatitis who had been admitted to Department of Pediatrics, Yonsei University College of Medicine during the period of 6 years from August, 1979 to July, 1985. The results were as follows: 1) Of 46 patients with chronic hepatitis, 40 cases were caused by hepatitis B virus, 3 cases by autoimmunity, and in 3 cases...
Case Report
A Case of Chronic Myelogenous Leukemia in a Child Treated in a Interferon.
Ill Soo Ha, Jon Lin Rhi, Se Jung Sohn, Dug Ha Kim, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1986;29(11):1232-1238.   Published online November 30, 1986
A child with Ph^positive chronic myelogenous leukemia was treated with human leukocyte interferon (Hu IFN-alpha). Hematologic remission was obtained in 16 weeks of treatment, and white blood cell count was decreased in number from 115,000 to 9,600. Platelet:count, spleen size, LDH and bone marrow M/E ratio were decreased in parallel, but there was no significant change in serum vitamin B12...
Original Article
A Clinical Observation on Maxillary Sinusitis with Asocated Chronic Cough in Children.
Sun Jong Kim, Jee Sung Kim, Byung Hak Lim, Im Ju Kang
Clin Exp Pediatr. 1986;29(9):969-978.   Published online September 30, 1986
From October 1984 to June 1985, 115 children aged 3 to 15 years with one month or more history of recurrent or persistent cough and a water’s sinus radiograph presenting greater than 6 mm mucosal thickening or opacification or air fluid level in one or both maxillary sinuses were analyzed & following results were obtained. 1)Most cases were aged 3 to 8...
Chronic Renal Failure in Children.
Yong Choi, Jong Duck Kim, Kwang Wook Ko, Jae Seung Lee, Pyung Kil Kim, Ja Hoon Koo
Clin Exp Pediatr. 1986;29(5):493-497.   Published online May 31, 1986
We analyzed data on children with chronic renal failure collected from 36 pediatric training hospitals during the period from Jan. 1, 1980 to Dec. 31, 1984. The following results were obtained: 1) Total number of children with chronic renal failure during the study period was 135. The incidence was about 1 per 2,000 in-patients and 2.09 per million children under 15...
Case Report
A Case of Chronic Granulomatous Disease.
C H Park, M R Roh, S C Park, J O Park, D H Lee, S J Lee
Clin Exp Pediatr. 1984;27(11):1141-1146.   Published online November 30, 1984
Chronic granulomatous disease is characterized by an inability of patients* leukocytes to generate hydrogen peroxide and to kill non-peroxide forming bacteria, such as staphylococci, E. coli and serratiae etc. We experienced a case of chronic granulomatous disease with recurrent pyogenic infection. It was diagnosed by clinical findings and laboratory examinations including NBT test. Clin- ical findings showed persistent diarrhea since birth, recurrent bacterial pneumonia, perianal abscess,...
A Case of Chronic Active Hepatitis with Vertical Transmission.
T H Son, T S Song, H J Park, M J Shin, J G Chi
Clin Exp Pediatr. 1984;27(2):164-169.   Published online February 28, 1984
We experienced a case of Chronic Active Hepatitis with vertical transmission in a 4-year-3-month old boy. Diagnosis of CAH was confirmed by histologic features of liver biopsy. The mode of infection in this case was suspected as vertical transmission by clinical history. His mother had acute hepatitis B in the last trimester of the pregnancy of this boy and had...
A Case of Chronic Atrial Tachycardia Managed with Digoxin and Reserpine.
Young Hee Kim, Young Ju Choi, Sang Il Rhee, Sang Woo Kim
Clin Exp Pediatr. 1984;27(1):79-83.   Published online January 31, 1984
An 1 8/12 year old girl had chronic, repetitive left atrial tachycardia and it was unresponsive to usual antiarrythmic drugs. The chief complaints were cyclic lethargy and irritability, occasionally associated with cyanosis and sweating. Her heart rate showed marked variation, depending upon the time of the day and her state of consciousness. ECG showed supraventricular tachycardia with ectopic pace-maker, proposed by...
A Case of Chronic Atrial Tachycardia.
Seung Won Park, Moo Young Oh, In Soon Park, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1983;26(9):905-908.   Published online September 30, 1983
We report a case of chronic atrial tachycardia in a 8 year-old boy. One year 3 month duration of chronic precordial palpitation is the only complaint on admission. Diagnosis was confirmed with characteristic EKG findings. Digitalis therapy was tried, but in vain. The clinical manifestations have been persistent during follow-up for 1 year 6 months since diagnosis.
Two Cases of Chronic Myelocytic Leukemia.
Hye Keun Kim, Hwa Young Kim, Young Youn Choi, Soon Pal Suh, Chang Soo Park
Clin Exp Pediatr. 1983;26(2):183-187.   Published online February 28, 1983
The authors experienced two cases of adult type of chronic myelocytic leukemia. We diagnosed it through the evaluation of both clinical and hematologic features, but Philadephia chromosomes were not detected. Patients had been treated with my 1 eran followed by some degree of remission. A brief review of literatures was made.
A Case of Chronic Active Hepatitis.
H J Park, H K Park, H J Chun, M J Shin, S C Kang
Clin Exp Pediatr. 1981;24(10):991-996.   Published online October 15, 1981
Chronic active hepatitis (CAH) is defined as ongoing inflammation within the liver sustained beyond the expected time of resolution. The etiology of CAH is not completely understood, but hepatitis B infection, drugs such as oxyphenisatin, isoniazid, and alpha-methyldopa, and altered immunity are considered. The most common findings are jaundice, hepatosplenomegaly, elevated serum transaminase activities, hypergammaglobulinemia, and positive "autoimmune" serologic tests,...


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