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A Case of Addison's Disease.

Journal of the Korean Pediatric Society 1988;31(12):1689-1695.
Published online December 31, 1988.
A Case of Addison's Disease.
In Hoon Lee, H. D. Lee, Hee Ju Jeon, Chan Yung Kim
Department of Pediatrics, College of Medicine Pusan National University, Pusan, Korea
소아 Addison병 1례
이인훈, 이형두, 전희주, 김찬영
부산대학교 의과대 학 소아과학교실
Received: 18 April 1988   • Accepted: 24 June 1988
Abstract
A 9-year-old girl with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was transferee! to our hospital because of darkish brown pigmentation of whole body and generalized weakness which had misunderstood cyanotic heart disease. On physical examination, she was poorly nourished and below 10 percentile in weight and height. Skin and mucous membrane were diffusely darkish brown, especially over the face, fingertips, toetips and gingiva. Laboratory studies showed low serum cortisol, high ACTH concentration, low Na/K ratio and low 24 hours urinary 17-hydroxycorticoids, but 8 hours intravenous ACTH stimulation test failed to rise the plasma cortisol and 24 hours urinary 17-hydroxycorticoids level.
Key Words: Addison’s disease, Chronic adrenal insufficiency


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