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A Case of Chronic Myelogenous Leukemia in a Child Treated in a Interferon.

Journal of the Korean Pediatric Society 1986;29(11):1232-1238.
Published online November 30, 1986.
A Case of Chronic Myelogenous Leukemia in a Child Treated in a Interferon.
Ill Soo Ha, Jon Lin Rhi, Se Jung Sohn, Dug Ha Kim, Hyo Seop Ahn, Chang Yee Hong
Department of Pediatrics、College of Medicine,Seoul National University
성인형 만성 골수성 백혈병을 가진 소아에서 인터페론을 사용한 치료경험
하일수, 이종린, 손세정, 김덕하, 안효섭, 홍창의
서 울대학교 의과대학 소아과학교실
Abstract
A child with Ph^positive chronic myelogenous leukemia was treated with human leukocyte interferon (Hu IFN-alpha). Hematologic remission was obtained in 16 weeks of treatment, and white blood cell count was decreased in number from 115,000 to 9,600. Platelet:count, spleen size, LDH and bone marrow M/E ratio were decreased in parallel, but there was no significant change in serum vitamin B12 level and LAP score. The patient was treated with maintainance dose of Hu IFN-alpha without any significant side effect for 23+weeks.
Key Words: Interferon, Chronic myelogenous leukemia.


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