- Review Article
- General Pediatrics
- Protecting our future: environmental hazards and children’s health in the face of environmental threats: a comprehensive overview
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Jungha Lee, Hyo-Bin Kim, Hun-Jong Jung, Myunghee Chung, So Eun Park, Kon-Hee Lee, Won Seop Kim, Jin-Hwa Moon, Jung Won Lee, Jae Won Shim, Sang Soo Lee, Yunkoo Kang, Young Yoo; The Environmental Health Committee of the Korean Pediatric Society
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Clin Exp Pediatr. 2024;67(11):589-598. Published online October 31, 2024
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· Exposure to air pollutants cause allergic and respiratory diseases as well as chronic kidney disease.
· Adequate physical activity and proper nutrition are essential for children to maintain good health.
· We must educate people about the harmful effects of noise, blue light, heavy metals and smoke.
· Government and society must actively decrease environ-mental hazards. |
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- Review Article
- Mammalian target of rapamycin inhibitors for treatment in tuberous sclerosis
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Won Seop Kim
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Clin Exp Pediatr. 2011;54(6):241-245. Published online June 30, 2011
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Tuberous sclerosis complex (TSC) is a genetic multisystem disorder that results from mutations in the TSC1 or TSC2 genes, and is associated with hamartomas in several organs, including subependymal giant cell tumors. The neurological manifestations of TSC are particularly challenging and include infantile spasms, intractable epilepsy, cognitive disabilities, and autism. The TSC1- and TSC2-encoded proteins modulate cell function via the... |
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- Original Article
- The characteristics of neurocardiogenic syncope in children
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Kyung Yeon Lee, Jin Young Lee, Myoung Hyun Kim, Jeong Eun Lee, Yong Dae Kim, Eun Ju Lee, Young Su Lim, Won Seop Kim
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Clin Exp Pediatr. 2008;51(5):512-517. Published online May 15, 2008
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Purpose : Syncope is relatively common in children and adolescents. Among the etiologies of syncope, neurocardiogenical syncope is the most common, but it is often confounded with seizure. We investigated the clinical features of patients under the age of 15 with neurocardiogenical syncope, compared to patients with neurologic disorders including epilepsy.
Methods : Among the children who visited the... |
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- A comparison of provoked seizures and febrile seizures
associated with minor infections
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Eun-Ju Lee, Won Seop Kim
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Clin Exp Pediatr. 2007;50(4):376-380. Published online April 15, 2007
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Purpose : Febrile seizures occur in childhood associated with a febrile illness not caused by infections of the central nervous system. Provoked seizures are identified with seizures in association with infections that do not usually affect the brain such as gastroenteritis, except criteria for other febrile seizures in this study. We studied seizures provoked by minor extracranial infections, to contrast... |
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- A clinical study of child bacterial meningitis in Daejeon and Chungcheong area : 2001-2005
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Yong Joo Lee, Soo Jin Lee, Ho Jin Park, Young Hyuk Lee, So Young Kang, Young Chang Kim, In Kyu Lee, Kyung Yeon Lee, Keon Su Lee, Won Seop Kim
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Clin Exp Pediatr. 2007;50(2):157-162. Published online February 15, 2007
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Purpose : The purpose of this study was to analyze the epidemiology, causative organism, clinical manifestation and prognosis of bacterial meningitis for children after the introduction of Haemophilus influenzae type b (Hib) vaccine in Daejeon and Chungcheong area.
Methods : We analyzed retrospectively 53 medical records who had been diagnosed with bacterial meningitis at 10 general or university hospitals... |
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- Risk Factors of Unprovoked Seizures after
Acute Symptomatic Seizures in Children
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Eun Ju Lee, Won Seop Kim
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Clin Exp Pediatr. 2007;50(11):1097-1103. Published online November 15, 2007
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Purpose : Acute symptomatic seizure is defined as a temporary seizure together with acute systemic, metabolic, or toxic insult in association with an acute central nervous system insult. And unprovoked seizure is defined as seizure without provocating factors. We studied the risk factors of unprovoked seizures after acute symptomatic seizure in children.
Methods : We retrospectively reviewed the records of... |
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- Medical Lecture Course
- Epilepsy and Oxygen Free Radicals
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Won Seop Kim
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Clin Exp Pediatr. 2005;48(9):920-923. Published online September 15, 2005
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Epilepsy is a neurological disorder from many molecular and biochemical responses. In the underlying mechanism, free radicals play an important role in seizure initiation and seizure-induced brain damage. Excessive production of oxygen free radicals and other radical species have been implicated in the development of seizures under pathological conditions and linked to seizure-induced neurodegeneration. |
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- Original Article
- A Clinical Study of Acute Symptomatic Seizures in Children
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Kyeong Eun Lee, Won Seop Kim
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Clin Exp Pediatr. 2000;43(9):1254-1262. Published online September 15, 2000
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Purpose : To determine the incidence, etiology, sex, age, seizure type and prognosis of acute
symptomatic seizures in children and evaluate the hypothesis that acute symptomatic status epilepticus(
SE) is associated with an increased risk of subsequent unprovoked seizure compared with
the risk of acute symptomatic seizure without SE.
Methods : Five hundred and sixty-eight convulsive children visited the Pediatric Department of
Chungbuk National University... |
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- Case Report
- A Case of Tuberous Sclerosis with Hydrocephalus and Multiple Cardiac Tumors in Neonatal Period
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Young Jun Song, Won Seop Kim, Beom Soo Park, Heon Seok Han
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Clin Exp Pediatr. 2000;43(2):294-299. Published online February 15, 2000
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Several different tumors in different tissues(including the central nervous system, heart, kidney, liver, bone, and soft tissues) are found to be associated with tuberous sclerosis. In the brain, this tumor characteristically arises from the floor of the lateral ventricle and often occluded the foramen of Monro. Cardiac tumor is among the earliest signs of tuberous sclerosis and occurs in over... |
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- Original Article
- Seizure Types and EEG Findings of Juvenile Onset Idiopathic Generalized Epilepsy
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Hyunmi Kim, Won Seop Kim, Jong Shin Kim, Kangho Cho, Ki Joong Kim, Yong Seung Hwang
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Clin Exp Pediatr. 1997;40(7):991-998. Published online July 15, 1997
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Purpose : Juvenile myoclonic epilepsy, juvenile absence epilepsy, and epilepsy wth
generalized tonic clonic seizure(GTCS) on awakening are the three syndromes of idiopathic
generalized epilepsy of adolescent onset currently included in the classification of epilepsy
syndromes of the International League Against Epilepsy(ILAE). Although they differ in their
predominant seizure types, the syndromes share several seizure types. Also, there are no
unique electrophysiologic or genetic markers.... |
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- Statistical studies on pediatric emergency room patients.
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Won Seop Kim, Young Jin Hong, Don Hee Ahn, Keun Chan Sohn
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Clin Exp Pediatr. 1991;34(1):7-15. Published online January 31, 1991
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The studies were carried out to analyze the emergency patient visited to the emergency room of the
National Medical Center under the 15 years old during the three-year period from Jan., 1985. to Dec.,
1987
The results were obtained as below.
1) During the 3-year periods, the total number of emergency patients under the 15 years of age was
4,394.
2) Forty one percents of the total patient... |
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- Clinical Analysis on Childhood Accidents.
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Won Seop Kim, Youn Jin Hong, Don Hee Ahn, Keun Chan Sohn
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Clin Exp Pediatr. 1990;33(12):1631-1638. Published online December 31, 1990
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We carried out a stastical & clinical analysis on 2,593 cases of childhood accidents visiting
emergancy room of National Medical Center during last 5 years, from Jan. 1, 1984 to Dec. 31, 1988.
The results were as follows:
1) The total percent of accidents among EMR visitors showed 6% increase in 1988 compared to that
of in 1984
2) The most common type of accidents was trauma... |
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