- Original Article
- Enterovirus 71-associated hand, foot and mouth diseases with neurologic symptoms, a university hospital experience in Korea, 2009
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Hye Kyung Cho, Na Yong Lee, Hyunju Lee, Hae Soon Kim, Jeong Wan Seo, Young Mi Hong, Seung Joo Lee, Sun Wha Lee, Doo Sung Cheon, Ji Young Hong, Byung Hak Kang, Jong-Hyun Kim, Kyung-Hyo Kim
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Clin Exp Pediatr. 2010;53(5):639-643. Published online May 31, 2010
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Purpose Hand-foot-mouth disease (HFMD) is a common viral illness in children, which is usually mild and self-limiting. However, in recent epidemics of HFMD in Asia, enterovirus 71 (EV71) has been recognized as a causative agent with severe neurological symptoms with or without cardiopulmonary involvement. HFMD was epidemic in Korea in the spring of 2009. Severe cases with complications including death have... |
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- Review Article
- Guidelines for childhood urinary tract infection
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Seung Joo Lee
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Clin Exp Pediatr. 2009;52(9):976-983. Published online September 15, 2009
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Urinary tract infection (UTI), the most common bacterial disease in childhood, is frequently associated with urinary tract anomalies (15-50%) and can induce renal scarring, which is a cause of hypertension and chronic kidney disease. Despite the high risk of renal scarring in infancy, the diagnosis may be delayed due to its nonspecific presenting symptoms; moreover, over-diagnosis is frequent due to... |
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- Original Article
- Bacterial meningitis in children experienced at a university hospital, 1993-2006
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Sung Yoon Cho, Tae Yeon Kim, Hyunju Lee, Kyung Hyo Kim, Eun Sun Yoo, Hae Soon Kim, Eun Ae Park, Kyung Ha Ryu, Jeong Wan Seo, Sejung Sohn, Seung Joo Lee
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Clin Exp Pediatr. 2008;51(10):1077-1084. Published online October 15, 2008
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Purpose : Despite the seriousness of bacterial meningitis in children, there is little information on the incidence, causative organisms, mortality rate and age distribution. We studied the frequency by age group and causal pathogens, and clinical characteristics in children with bacterial meningitis in the private sector in Korea.
Methods : The medical records containing the data on bacterial meningitis patients... |
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- Benign Transient Hyperphosphatasemia of Infancy and Childhood
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Jung Hyun Kwon, Ji Hye Park, Hae Soon Kim, Seung Joo Lee, Mi Ae Lee
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Clin Exp Pediatr. 2005;48(3):306-309. Published online March 15, 2005
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Purpose : The aim of study is to investigate the clinical manifestations and the etiology of markedly-elevated serum alkaline phosphatase(ALP) levels in children without accompanying liver or bone disease.
Methods : The serum ALP and other biochemical laboratory data of 4,989 patients attending the pediatric department of Ewha Womans University Mokdong Hospital between January 2002 to December 2002 were studied. The... |
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- The Change in Intestinal Lactobacillus Count among Healthy Neonates
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Hyun Joo Lee, Hyun Ji Lee, Su Jin Cho, Jung Wan Seo, Seung Joo Lee, Eun Ae Park
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Clin Exp Pediatr. 2004;47(8):833-838. Published online August 15, 2004
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Purpose : Enhancing overall health by preventive and therapeutic use of probiotics has shown great promise on inflammatory, infectious, neoplastic disorders, allergies, et al. To attain preliminary data for the use of probiotics, we have studied the change in intestinal flora, Lactobacillus count among healthy, full term neonates.
Methods : Fresh stool samples were collected on the 2nd or 5th day... |
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- Prognostic Value of Repeated Cerebrospinal Latex Agglutination Testing in Bacterial Meningitis
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Soo Jeong Lee, So Hyun Ahn, Su Jin Cho, Hae Soon Kim, Seung Joo Lee
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Clin Exp Pediatr. 2003;46(4):345-350. Published online April 15, 2003
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Purpose : Bacterial meningitis is a serious infection of childhood associated with a significant morbidity and mortality. Repeated cerebrospinal fluid(CSF) examination is a useful prognostic indicator and a delayed sterilization is associated with a higher incidence of neurologic abnormalities. In this study we tried to determine the prognostic value of repeated CSF latex agglutination testing.
Methods : We retrospectively evaluated 19... |
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- Case Report
- A Case of Kawasaki Disease Associated with Acute Renal Failure and Necrotizing Myositis
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So Hyun Ahn, So Yun Shim, Sejung Sohn, Seung Joo Lee, Un Seop Han
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Clin Exp Pediatr. 2003;46(2):207-209. Published online February 15, 2003
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Kawasaki disease is an acute febrile vasculitis affecting primarily infants and young children. In addition to the cardiovascular involvement, it may cause inflammatory changes in various organs and body systems : digestive, respiratory, urinary, nervous and musculoskeletal. A case is reported of atypical Kawasaki disease associated with acute renal failure and necrotizing myositis in the right gastrocnemius in a 10-year-old... |
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- Original Article
- Usefulness of Low Risk Criteria for Serious Bacterial Infection
Among Febrile Infants Younger than Three Months of Age
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So Hyun Kim, Ji Ah Jung, Hae-Soon Kim, Eun Sun Yoo, Sejung Sohn, Jeong Wan Seo, Seung Joo Lee
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Clin Exp Pediatr. 2002;45(8):967-972. Published online August 15, 2002
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Purpose : A retrospective study was undertaken to evaluate the usefulness of low risk criteria for identifying febrile infants younger than three months unlikely to have serious bacterial infection.
Methods : We conducted a retrospective study of 527 infants younger than three month with a axillary temperature ≥37.4℃. If they met the following all four criteria, appear well, WBC 5,000- 20,000/mm3,... |
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- A Clinical Manifestation of Meckel's Diverticulum
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Jin Beom Lee, Yong Soon Lee, Eun Sun Yoo, Hae Soon Kim, Se Jeong Son, Eun Ae Park, Seung Joo Lee, Sun Hee Sung, Jeong Wan Seo
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Clin Exp Pediatr. 2002;45(4):466-472. Published online April 15, 2002
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Purpose : The diagnosis of Meckel's diverticulum is difficult and delayed because it presents with various clinical symptoms. We evaluated clinical, imaging and pathologic findings of Meckel's diverticulum to facilitate detection of Meckel's diverticulum in children.
Methods : Review of clinical, imaging, surgical and pathological findings in 10 children aged 7 days to 14 years with Meckel's diverticulum during an 8-year... |
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- Case Report
- A Case of Bilateral Spontaneous Tension Pneumothorax
Associated with Mycoplasma pneumoniae Infection
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Jae Won Lee, Mi Young Heo, Hae Soon Kim, Seung Joo Lee
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Clin Exp Pediatr. 2002;45(3):401-405. Published online March 15, 2002
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Mycoplasma pneumoniae(M. pneumoniae) is the leading cause of pneumonia in school-age children and young adults. The clinical courses are usually mild but recently, severe cases were reported such as lung abscess, Swyer-James syndrome and adult respiratory distress syndrome. Spontaneous pneumothorax associated with M. pneumoniae infection is rare. Carlisle reported a 6-year-old patient with bilateral spontaneous pneumothorax associated with M. pneumoniae... |
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- Original Article
- The Utility of Serum Prealbumin as a Biochemical Marker for
Nutritional Adequacy in Neonates
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Ji A Jung, Eun Ae Park, Jeong Wan Seo, Seung Joo Lee
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Clin Exp Pediatr. 2000;43(5):605-610. Published online May 15, 2000
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Purpose : The purpose of this study was to determine the utility of serum prealbumin as a biochemical marker for nutritional adequacy in neonates.
Methods : From March 1998 to May 1999, 71 fullterm(54 AGA, 9 LGA, 8 SGA) and 46 preterm neonates were enrolled. The correlations among prealbumin, albumin, birth weight and gestational age were obtained. Serum concentrations of albumin... |
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- Diagnostic Value of Urine Latex Test In Bacterial Meningitis
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Seung Min Lee, Eun Ae Park, Seung Joo Lee
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Clin Exp Pediatr. 2000;43(1):55-59. Published online January 15, 2000
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Purpose : Bacterial meningitis in childhood carries significant mortality and morbidity, so accurate
and rapid diagnosis is important. Cerebrospinal fluid(CSF) latex agglutination test has been used
for rapid diagnosis of bacterial meningitis. However, urine may be the best specimen for a latex
test, because bacterial antigens are concentrated in the urine. The study tried to determine the
diagnostic value of urine latex test in... |
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- The Risk Factors of Renal Scar in Childhood Acute Pyelonephritis
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Soo Ja Hwang, Seung Joo Lee
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Clin Exp Pediatr. 1999;42(4):545-552. Published online April 15, 1999
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Purpose : To observe the risk factors of renal scar in children with first acute pyelonephritis (APN) who had photopenic defects on initial 99mTc-DMSA spect renal scan.
Methods : Forty-seven children with first APN(M : F=33 : 14) who were admitted to Ewha Womans University Hospital from September, 1993 to Febrary, 1998, were divided into renal scar group(N=17, Kidney unit(KU)=18) and... |
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- Case Report
- Levamisole-Induced Reversible Agranulocytosis in Children with Steroid Dependent Nephrotic Syndrome
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Su Jin Lee, Su Ja Hwan, Eun Seon Yoo, Seung Joo Lee
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Clin Exp Pediatr. 1999;42(4):576-579. Published online April 15, 1999
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Levamisole has been used for nephrotic syndrome due to its immunostimulating, immunomodulating, and steroid-sparing effects. Agranulocytosis, a serious side effect of levamisole, was rare and mostly associated with autoimmune disease, neoplastic disease and HLA B27 except one case in a nephrotic syndrome who was treated with high-dose(5mg/kg QOD) levamisole. This 15 year-old girl with steroid dependent nephrotic syndrome, who was... |
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- Erratum
- Reference Values of Hematologic and Biochemical Parameters of Nutrition around Weaning Period
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Seung Joo Lee, Jeong Wan Seo, Jae Ock Park, Jae Hoon Shin, Hae Ran Lee, Ji Tae Chung, Hae Il Chung
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Clin Exp Pediatr. 1999;42(1):6-14. Published online January 15, 1999
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Purpose : To determine the reference values of hematologic and biochemical parameters of nutrition around the weaning period.
Methods : From February 1996 to March 1997, several nutritional laboratory values were evaluated in 130 healthy babies and 120 inpatients in the recovery stage of acute illness at six general hospitals.
Results : Reference values in 9-month-old healthy babies(range : 6-12 months) were... |
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- Original Article
- The Utility of Serum Prealbumin Concentrations for Short-term Nutritional Assessment in Patients with Acute Diarrhea
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Kyoung Ah Lim, Hae Soon Kim, Jeong Wan Seo, Seung Joo Lee
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Clin Exp Pediatr. 1999;42(1):88-93. Published online January 15, 1999
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Purpose : To evaluate the usefulness of serum prealbumin concentration for the nutritional assessment of acute diarrhea.
Methods : From February 1997 to August 1997, ninety patients with acute diarrhea(age, 4-24 months) were randomly assigned into two groups on the basis of their intakes for 2 days prior to admission : liquid diet group(N=56, clear liquid and/or oral electrolyte solutions), and... |
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- The Clinical Significance of Serum Sodium Concentration in Febrile Convulsion
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So Young Park, Seung Joo Lee
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Clin Exp Pediatr. 1998;41(9):1262-1267. Published online September 15, 1998
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Purpose : Recently hyponatremia was reported to be common in febrile convulsion and related to the probability of a repeated convulsion. It was documented that hyponatremia lowers the threshold for convulsion in experiment animals. We therefore studied the relationship between hyponatremia and febrile convulsion.
Methods : Serum sodium concentration was measured in 82 children with febrile convulsions and 66 age-matched febrile... |
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- The Diagnostic Value of CSF Tumor Necrosis Factor-α for Early Diagnosis of Bacterial Meningitis
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So Young Park, Soo Ja Hwang, Eun Ae Park, Jung Wan Seo, Seung Joo Lee
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Clin Exp Pediatr. 1998;41(8):1078-1083. Published online August 15, 1998
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Purpose : During the course of bacterial meningitis, TNF-α produced by macrophages and monocytes in response to LPS and other inflammatory and immune stimulation, is now recognized as a primary mediator in the pathogenesis of infection, injury and inflammation and in the process of host defence. TNF-α was increased vascular permeability by inducing morphologic and structural changes of endothelial cells... |
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- Random Urine Ca/Cr Ratio in Healthy Neonates
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Hea Young Lee, So Young Park, Eun Sun Yoo, Eun Ae Park, Seung Joo Lee
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Clin Exp Pediatr. 1998;41(3):378-382. Published online March 15, 1998
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Purpose : Recently, in high risk preterm infants, we experienced high incidence of hypercalciuria, nephrolithiasis & nephrocalcinosis. To screen hypercalciuria, we need the normal value of random urine Ca/Cr ratio in healthy neonates according to gestational age, postnatal age, milk and calcium intake.
Methods : Random urine Ca/Cr ratio was checked in 260 healthy full-term infants at the 2-7th day, and... |
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- The Effect of Low-Dose Dopamine on the Renal Function of Asphyxiated Neonates
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Seung Yeon Nam, Eun Ae Par, Seung Joo Lee
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Clin Exp Pediatr. 1998;41(12):1685-1692. Published online December 15, 1998
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Purpose : Low-dose dopamine(0.5-3μg/kg/min) increases renal blood flow, glomerular filtration rate and natriuresis and has protective and therapeutic effects on oliguric renal failures. Asphyxia is the most common cause of acute renal failure in neonates. But the protective effects of dopamine have never been reported in asphyxiated neonates. So we reported the effects of low-dose dopamine on the renal function... |
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- Case Report
- A Case of Myositis Ossificans Progressiva
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So Young Park, Su Jin Lee, Ji A Chung, Seung Joo Lee
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Clin Exp Pediatr. 1998;41(11):1601-1605. Published online November 15, 1998
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Myositis ossificans progressiva(MOP) is a rare, slow progressive autosomal dominant disorder that principally affects children under the age 10 years. It is characterized by progressive fibroblastic proliferation, and subsequent calcification and ossification of subcutaneous fat, muscles, tendons, aponeuroses and ligaments. The disorder is often associated with symmetrical malformations of the digits, especially microdactyly or adactyly of the thumbs and great... |
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- Erratum
- A Survey on the Factors Related to the Failure of Breast-feeding
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Seung Joo Lee, Jeong Wan Seo, Jae Ock Park, Jae Hoon Shin, Hae Ran Lee, Ji Tae Chung, Hae II Chung
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Clin Exp Pediatr. 1997;40(10):1336-1346. Published online October 15, 1997
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Objective : The breast-feeding rate has decreased in Korea despite of the active
encouraging effort of breast-feeding for the last 10 years. So we investigated the factors
that are related to breast-feeding failure.
Method : 1807 specific questionares of mothers who visited the six university hospitals
in Seoul from October 1993 to December 1995 were analysed by ANOVA and multiple
logistic regression using SAS program.
Results... |
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- Original Article
- Arterial Oxygen Desaturation after Salbutamol Nebulization in Wheezy Infants and Children
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Eun Sun Yoo, Jung Won Seo, Seung Joo Lee
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Clin Exp Pediatr. 1996;39(7):953-961. Published online July 15, 1996
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Purpose : Nebulized selective β2-adrenoreceptor agonists have been widely used in acute asthma
and selectively in acute bronchiolitis. However, nebulized salbutamol have been reported to cause
arterial oxygen desaturation in some of the acute bronchiolitis and severe asthma patients. This
may be the results of a paradoxical bronchoconstriction linked to acidic and hyper-osmolar
nebulized salbutamol solution and etc. We assessed the changes in arterial... |
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- Serum IgE Standardized for Age in Korean Children and Its Diagnostic Reliability in Childhood Asthma
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Myung Su Lee, Eun Sun Yoo, Hye Sun Kim, Eun Ae Park, Jeong Wan Seo, Seung Joo Lee
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Clin Exp Pediatr. 1996;39(3):397-403. Published online March 15, 1996
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Purpose : IgE was identified by Ishizaka as an antibody that is reacted at Type I
hypersensitivity reaction, and has been used in the diagnosis of allergic disease and the differential diagnosis of extrinsic and intrinsic asthma. But there was some confusing in the diagnosis because of the broad range of measured serum IgE. Recently it was reported that serum IgE... |
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- Erratum
- Special Infant Formula
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Seung Joo Lee
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Clin Exp Pediatr. 1996;39(2):180-186. Published online February 15, 1996
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- Original Article
- The Risk Factors related to Recurrent Intussusception by Ultrasonography
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Eun sun Yoo, Jeong Wan Seo, Seung Joo Lee
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Clin Exp Pediatr. 1996;39(12):1707-1716. Published online December 15, 1996
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Purpose : We investigate the risk factors of recurrence after first intussusception.
Methods : We have studied the relationship of the clinical features and ultrasonographic findings and the risk of recurrent intussusception in 97 patients with reduced intussusception including 22 recurrent intussusception who admitted at the department of pediatrics at Ewha Womans University Mok-dong hospital from September 1993 to Feburary 1996.
Results... |
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- Case Report
- An Autopsy Case of Tracheal Agenesis Type 2
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Hyun Joo Lee, Eun Ae Park, Seung Joo Lee, Mi Jeong Kim, Soon Hee Seong
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Clin Exp Pediatr. 1996;39(12):1759-1762. Published online December 15, 1996
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Tracheal agenesis is the rare and uniformly lethal anomaly that presents with severe
respiratory distress and aphonia after birth. In this anomaly, the trachea is usually absent and air is reaching the bronchi through a communication with the esophagus. The diagnosis should be suspected in a nowborn infant with respiratory distress whose intubation is difficult.
We report an autopy case of tracheal... |
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- Original Article
- The Effect of Allopurinolon the Ischemia-reperfusion RenalInjury in Young Rats
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Seung Joo Lee
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Clin Exp Pediatr. 1996;39(11):1576-1585. Published online November 15, 1996
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Objective : Oxygen free radicals has been reported to be the critical cellular mediators of
experimental ischemia-reperfusion renal injury. We examined the protective effect of allopurinol
(an xanthine oxidase inhibitor) on the renal damage by reperfusion in the ischemic rat kidney.
Methods : To induce renal ischemia, the Sprague-Dawley rats(weight 70-80g) were placed in a
sealed 5L jar with 8% O2-92% N2 gas mixture... |
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- Diagnostic Value of 99mTc-DMSA Renal Scan for Early Diagnosis of Acute Pyelonephritis in Children with Febrile Urinary Tract Infection
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Soo Ja Hwang, Eun Ae Park, Jeong Wan Seo, Seung Joo Lee, Sun Whan Lee
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Clin Exp Pediatr. 1996;39(11):1586-1593. Published online November 15, 1996
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Purpose : For prevention of renal scar, early diagnosis and treatement of acute pyelonephritis
are important in children with febrile urinary tract infection. But it has been difficult to
differentiate acute pyelonephritis from lower urinary tract infection. We have performed this study
to evaluate the diagnostic value of 99mTc-DMSA renal scan and to clarify the relationship among
acute pyelonephritis, vesico-ureteral reflux and renal scar.
Methods... |
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- Case Report
- A Case of Eosinophilic Cystitis in Child
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So Young Park, Seung Joo Lee
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Clin Exp Pediatr. 1995;38(8):1155-1159. Published online August 15, 1995
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Since Brown first descirbed the eosinophilic granuloma in 1960, 45 cases of eosinophilic cystitis have been reported in the literature, including 10 pediatric cases. In Korea, only four adult cases were reported. Eosinophilic cystitis is characterized by severe infiltration o eosinophils into the mucosa, submucosa and muscularis of bladder wall which causes irritative voiding symptoms. This lesions have been frequently... |
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- Original Article
- 3 Cases of Kawasaki Disease Associated Thrombocytopenia
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Hye Soon Kim, Young Mi Hong, Seung Joo Lee
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Clin Exp Pediatr. 1995;38(12):1686-1690. Published online December 15, 1995
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Kawasaki disease may be associatde with a variety of hematologic abnormalities, the most characteristic being thrombocytosis. Thrombocytopenia, in contrast, appears to occur rarely in children with this disease. Hera et al observed the 2% manifested thrombocytopenia early in their illness. To our knowledge, early thrombocytopenia has not been reported in other populations, We report the case of a children with... |
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- Effect of Perinatal Asphyxia and Gentamicin on Urinary β2-microglobulin Concentration and Renal Function in Fullterm Neonates
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Hoo Jae Hann, Seung Joo Lee
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Clin Exp Pediatr. 1994;37(7):976-985. Published online July 15, 1994
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Perinatal asphyxia can cause ischemic injury to immature kidney of neonates. Proximal renal tubule is the most sensitive area, showing various manifestations ranging from mild reversible injury to irreversible tubular necrosis. Aminoglycosides can be nephrotoxic in therapeutic range in immature or damaged kidney. These are the very important factors to be taken into corsideration on fluid therapy and nephrotoxic drugs... |
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- Hypercalciuria in High Risk Neonate
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Eun Sun Kim, Seung Joo Lee
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Clin Exp Pediatr. 1994;37(3):322-331. Published online March 15, 1994
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The incidence and risk factors for hypercalciuria were studied in 23 sick preterm (Group I), 36 well preterm (Group II), 16 sick term (Group III) and 41 well term (Group IV) neonates who were admitted to NICU and nursery of Whwa Woman's University Hospital from May 1988 to February 1992.
The results were as follows:
1) The incidences of hypercalciuria were 73.9%... |
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- A Survey on the Present Status of Weaning
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Seung Joo Lee, Jae Ok Park, Chang Sung Sohn, Hae Ran Lee, Jae Hoon Shin, Hae Il Chung, Seung Il Kim
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Clin Exp Pediatr. 1994;37(12):1643-1656. Published online December 15, 1994
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Purpose : To add proper solid food during the ideal weaning period is very important to supply adequate nutrition for the rapid growt and to achieve proper feeding habits in later infancy. We tried to survey the problems in weaning in Korea.
Methods : The Present status of infant weaning was sutneyed 6 university hospital in Seoul and 4 rural goverment... |
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- Case Report
- Two Case of Psedohypoaldosteronism Type 1
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Ji Eun Lee, Jung Wan Seo, Seung Joo Lee
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Clin Exp Pediatr. 1994;37(1):122-128. Published online January 15, 1994
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Pseudohypoaldosteronism type 1 is a genetic renal tubular disease of salt wasting, presenting in young infants. Tubular unresponsiveness to elevated endogenous an exogenou aldosterone is the suggested pathogenetic mechanism. Oral sodium chloride supplementation relieve the clinical symptoms and electrolyte distrubances.
We experienced 2 cases of PHA type 1 in 38-day and 450day old male infants who were presented with failure to... |
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- Original Article
- Urinary Tract Infection and Neonatal Circumcision
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Seung Joo Lee
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Clin Exp Pediatr. 1992;35(8):1035-1043. Published online August 15, 1992
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An association between urinary tract infection in male infants and uncircumcised status has been suggested recently. Male predominance of UTI in most reports in Korea may be related to this uncircumcised status.
The present study was prospectively performed between Mar. 1989 and May. 1991 to investigate this relationship and the effect of neonatal circumcision on the intraurethral bacterial flora.
1) The... |
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- Case Report
- Adult Respiratory Distress Syndrome in Infancy
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Hoo Jae Hann, Young Mi Hong, Seung Joo Lee
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Clin Exp Pediatr. 1992;35(2):245-251. Published online February 15, 1992
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Adult Respiratory distress Syndrome (ARDS) is a clinical entity characterized by respiratory distress and diffuse pulmonary infiltrates due to increased permeability after various kinds of insult to alveolar-capillary membrane.
We experienced a case of ARDS in a 3-1/2 month old girl after Pseudomonas pneumonia, cardiac arrest and generalized convulsion.
This is the report on her clincal and autopsy findings with brief review... |
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- Original Article
- Screening of urinary Tract Infection in High-Risk Neonates
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Hyeon Joo Choi, Seung Joo Lee
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Clin Exp Pediatr. 1992;35(12):1683-1679. Published online December 15, 1992
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Since the urinary tract infection (UTI) in neonates is often associated with major urologic anomalies, early diagnosis is essential. In the screening of UTI by urine bag, contamination is a commonly encountered problem. Suprapubic bladder puncture has therefore been recommended as the best method to confirm UTI. The purpose of this study is to assess the frequency and characteristics of... |
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- Early detection of gentamicin nephrotoxicity using urinary beta2-microglobulin in neonates.
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Mi Kyung Kim, Seung Joo Lee
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Clin Exp Pediatr. 1991;34(7):940-948. Published online July 31, 1991
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Gentamicin, commonly used antibiotics in neonatal care, has a nephrotoxicity, but it is difficulto to
assess renal function in early stage.
This study evaluated the renal function and urinary β2-microglobulin excretion in 17 gentamicin
treated and 11 control neonates.
The results are as follows.
1) Urinary 02-M in gentamicin treated neonates were 0.84±0.17mg/L at postnatal day 1 and
increased to 5.99±1.15mg/L at day 4, 14.17±2.39mg/L at day... |
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- The effect of ultrasonic nebulized salbutamol in the first attacked wheezy infants.
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Soo Young Kweon, Young Mi Hong, Gyung Hee Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1991;34(11):1505-1511. Published online November 30, 1991
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Wheezing is one of the most common symptom in the first 2 year of life.
Although the effect of bronchodilator in wheezy infants was still debating, various form of
bronchodilator has been tried untill now.
This study was done to estimate the value of ultrasonic nebulized salbutamol as a bronchodilator
test and maintenance therapy compared to epinephrine and aminophylline in 44 wheezy infants below
24... |
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- A Case of Acute Mixed Lineage Leukemia (ANLL with TII) with neutropenic Enterocolitis.
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Hyeon Joo Choi, Young Suk Koh, Young Mee Hong, Seung Joo Lee, Kee Suk Hong, Keum Ja Choi
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Clin Exp Pediatr. 1990;33(9):1281-1287. Published online September 30, 1990
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We report a case of acute mixed lineage leukemia with both lymphoid and myeloid lineage
characteristics (ANLL with Til) in a twelve-year-old girl who presented with fever and multiple
petechiae. Bone marrow remission was obtained by treatment with acute lymphoid leukemia regiman
(CCSG 106A). During induction chemotherapy, the patient was complicated by intestinal perforation
due to neutropenic enterocolitis but recovered by surgical intervention and... |
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- The Change of Anti-HBs Titer after Hepatitis B Vaccination in Newborn.
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Ji Hye Kang, Young Mi Hong, Seung Joo Lee
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Clin Exp Pediatr. 1990;33(5):598-605. Published online May 31, 1990
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Hepatitis B vaccination is an accepted preventive measure for all newborn as well as the risk
group. However, there is some uncertainty about the persistence of anti-HBs and the timing of
booster vaccination.
We studied anti-HBs titer, positive rate and minimum protective rate in relation to time interval
after the third vaccination in 102 infants bom to HBsAg negative mother (Group I) and 52... |
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- A Case of Transient Myeloproliferative Disorder in Down's Syndrome.
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Ji Hye Kang, Young Mi Hong, Kyung Hee Kim, Seung Joo Lee, Ki Sook Hong, Ok Kyung Kim, Je Geun Chi
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Clin Exp Pediatr. 1990;33(2):252-258. Published online February 28, 1990
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Transient myeloproliferative disorder has been reported in infant with Down's syndrome during
neonatal period.
This is clinically and hematologically indistinguishable from congenital acute leukemia. In contrast
to congenital leukemia, complete clinical and hematological recovery occurs within weeks to months
of diagnosis without antileukemic treatment.
A neonate presented with jaundice, hepatosplenomegaly and mongoloid face was diagnosed as
Transient myeloproliferative disorder.
We report this case with a review of... |
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- A Study on Anemia of Acute Infectious Disease in Children.
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Hae Won Lee, Young Mi Hong, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1990;33(1):75-80. Published online January 31, 1990
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The anemia of acute infectious disease has come to attention recently, since iron deficiency anemia
has decreased. We screened for anemia in children admitted to Ewha Womans University Hospital
due to acute infectious disease between January 1, 1986 and July 31, 1988, and studied the incidence
and characteristics of anemia in acute infectious diseases.
The result were as follows:
1) The incidence of anemia in acute... |
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- Clinical Strudy of chlamydial Pneumonia in Early Infants.
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Mi Kyung Kim, Young Mi Hong, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1990;33(1):51-58. Published online January 31, 1990
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We studied Chlamydiazyme test in 55 infants below 6 months of age with lower respiratory tract
infection, admitted to the Pediatric ward of Ewha Womans University Hospital, between October 1,
1987 and February 28, 1989. The results were as follows.
1. The overall incidence of Chlamydial pneumonia was 14,5% (8/55). All of them were below 2
months of age, so the incidence in infants below... |
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- Idiopathic Hypercalciuria in Children.
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Kyung Ha Ryu, Seung Joo Lee, Keun Lee, Jae Sun Jung
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Clin Exp Pediatr. 1989;32(6):809-815. Published online June 30, 1989
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Idiopathic hypercalciuria is defined as increased urinary excretion of calcium in normocalcemia
without primary cause. It is associated with urinary symptoms, such as hematuria but it occurs
without any symptoms too. If left untreated, it may cause kidney stone, dimineralization of bone, or
other problem. The incidence of idiopathic hypercalciuria was 3.9% in asymptomatic group compared
to 5% in unselected populations in this study.... |
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- Primary Vesicourteral Reflux in Children.
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Seong Hee Choi, Seung Joo Lee
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Clin Exp Pediatr. 1989;32(4):542-549. Published online April 30, 1989
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The primary vesicourteral reflux is the reflux of urine from the bladder to ureter and renal pelvis
due to congenital incompetence of valvular mechanism at the ureterovesical junction. It can result in
the development of renal scars(reflux nephropathy), particularly in association with urinary tract
infection and intrarenal reflux. The authors studied 21 patients with primary vesicourteral reflux
who were admitted to department of... |
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- A case of Guillain-Barré syndrome in a child treated with plasmapheresis.
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Hae Won Lee, Hoo Jae Han, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1989;32(11):1592-1597. Published online November 30, 1989
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We experienced a case of Guillain -Barré syndrome in a 12-year-old female patient who had
progressive motor weakness and showed rapid recovery with plasmapheresis and supportive therapy
in acute stage.
A brief review of the related literature was added. |
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- A case of Idiopathic Crescentic Glomerulonephritis.
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Mi Kyung Kim, Hyun Joo Choi, Seung Joo Lee, Ok Kyung Kim
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Clin Exp Pediatr. 1989;32(10):1435-1441. Published online October 31, 1989
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Idiopathic crescentic glomerulonephritis is a very rare disease especially in children with poor
prognosis. We experienced a case of idiopathic crescentic glomerulonephritis in a 4-year-old male
patient who presented initially with a nephrotic syndrome and progressed to a rapidly progressive
glomerulonephritis.
We review literatures briefly. |
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- PPD Conversion Rate and Complications According to the Different Time of BCG Vaccination.
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Kyung Hyo Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1987;30(5):487-490. Published online May 31, 1987
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BCG vaccination shortly after birth has shown to protect against tuberculosis in some studies.
PPD conversion rate and complications were compared between 174 neonates who received BCG
vaccine within 1 week after birth and 330 infants who received BCG vaccine at the 1 month of age.
The results were as follows:
1) The PPD conversion rate was 20.11% in the neonates who received vaccine within... |
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- A Prospective Study ot Neonatal Acute Renal Failure: The Significance of Various Diagnostic Indices.
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Kyung Hyo Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1987;30(4):378-384. Published online April 30, 1987
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Acute renal failure is defined as a sudden decrease in renal function resulting in progressive
retention of nitrogenous waste products. Acute renal failure should be suspected in any infant who has
a sustained decrease in urine output to less than 1 ml per kg per hour, a blood urea nitrogen level
above 20 mg per dl, a serum creatinine level greater than 1.0... |
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- The Study of Creatinine Clearance in Neonates.
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Dong Sun Hong, Moon Ja Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1987;30(2):139-143. Published online February 28, 1987
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The creatinine clearance rate, an index of glomerular filtration rate, has been reported to develop
according to gestational and postnatal age.
The purpose of this study is to examine changes in creatinine clearance with gestational age and
postnatal age in preterm and full term healthy neonates.
The results were as follows:
1) The creatinine clearance rate increased according to gestational age.
2) The most in creament of creatinine... |
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- Sodium Homeostasis by Neonatal Kidney.
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Seung Joo Lee
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Clin Exp Pediatr. 1987;30(1):17-25. Published online January 31, 1987
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Sodium homeostasis by neonatal kidney is important during the postnatal adaptation of body fluid.
It is mainly dependent to renal function which was differently maturated by gestational and postnatal ages.
I studied the postnatal changes of daily Na intake, urine Na, Na balance, FEN a and Serum Na
concentration in neonates with different gestational age.
In this study, I demonstrated that more increased urinary... |
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- Postnatal Changes of Serum Creatinine Levels in Neonates.
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Jeong Wan Seo, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1986;29(9):948-953. Published online September 30, 1986
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The concentration of creatinine, one of the simple and commonly used indices of glomerular filtration rate in children and adults, has been reported to be appreciably raised and variable during the first month of life.
This study examined the effect of gestational age(G.A.) on the postnatal changes of creatinine in preterm and full-term neonates. The results were as follows;
1) The mean... |
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- The Effect of Intravenous Dextrose Water Given to Mother During Labor on Sodium Concentration of Maternal and Cord Serum.
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Soo Kyung Chung, Dong Suk Suh, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1986;29(8):840-844. Published online August 31, 1986
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We studied the influence of intravenous electrolyte-free dextrose solution given to the mother during labor on the change of maternal and cord serum concentrations and the incidence of hyponatremia in 109 mothers and their newborns. 1) Na+ concentrations of maternal and cord serum in study group given intravenous electrolyte free dextrose solutions were 134.57土2.43 and 134.54±2.95, which was significantly lower,... |
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- Serum IgE Levels and Incidence of Atopic Disease according to Infant Diet.
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Jeong Wan Seo, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1985;28(8):751-755. Published online August 31, 1985
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The role of breast feeding and dietary elimination of cow's milk as a mean of preventing atopic disease in infants remains controversial. From May 1983 to August 1984，the relationships between the type of feeding in early
infancy and incidence of atopic disease were studied in 238 babies of less than 3 years of age and their serum IgE levels were compared.... |
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- Case Report
- A case of Idiopathic pulmonary hemosideroisis.
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Yeong Hee Kim, Jeong Hee Lee, Seung Joo Lee, Keun Lee, Ok Kyung Kim, Doo Yeon Lee
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Clin Exp Pediatr. 1985;28(2):182-186. Published online February 28, 1985
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Idiopathic Pulmonary Hemosiderosis is a rare disease characterized by recurrent attacks of hemoptysis, iron deficiency anemia and pulmonary infiltration on chest X-ray. We experienced a case of Idiopathic Pulmonary Hemosiderosis in a 3 year-old boy with recurrent attacks of dyspnea, pallor and chest infiltration on X-ray, without underlying pulmonary disease. Diagnosis was established by hemosiderin and hemosiderin-laden macrophage on lung... |
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- Original Article
- Effects of Antenatal Indomethacin on Neonate.
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Ja Ye Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1985;28(11):1066-1072. Published online November 30, 1985
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Prostaglandins play an important role in mediating uterine contractions and thus may also be involved in the triggering of premature labor and spontaneous abortion. Consequently inhibition of prostaglandin synthesis has been suggested as a potential means of inhibiting premature labor. There are many controlled studies which have described the use of indomethacin for inhibition of premature labor with success. But... |
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- Culture Study in Neonatal infection.
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Ja Ye Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1984;27(5):433-438. Published online May 31, 1984
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Bacterial infection is a frequent and important cause of morbidity and mortality in the neonatal period. Knowing the changing pattern of neonatal bacterial infections is important and recently the group B streptococcus has been vieing with Coliforms for preeminence. This study was undertaken to observe the pattern of bacteria in the neonatal infections and for detection of group B streptococcus.... |
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- Case Report
- A Case of Clinical Botulism.
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Yuoug Suk Ko, Jung Hee Lee, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1984;27(12):1223-1226. Published online December 31, 1984
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A 5-year-old girl was admi竹ed to the department of Pediatrics, Ewha Womans University
Hospital on October 21th, 1983 with weakness and lethargy of 5 days duration. Her younger
brother expired on the same day aftsr 1 day illness of the same symptoms, and there was a
other children who died following similar clinical course in the same area.
Even though the diagnosis of botulism... |
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- Original Article
- A Clinical Study of Neonatal Convulsion.
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Moon Ja Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1983;26(7):640-646. Published online July 31, 1983
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We observed 62 cases of neonatal convulsion who were admitted to the department of
Pediatrics, Ewha Womans University Hospital during the 6 1/2 year period from January,
1976 to June, 1982.
The following results were obtained,
1. The etiology of neonatal convulsion were, hypoxic brain damage (38.7%), hypocalcemia (14. 5%), infection(12.9%), hyponatremia(6.5%) hypoglycemia(3.2%), hypernatremia(1.6%)and unknown(22.6%).
2. The onset of most neonatal convulsion was within the 3rd... |
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- Respiratory Distress Syndrome of the New born Infants and Complications of Pregnancy.
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Yoon Joo Choi, Eun Ai Lee, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1983;26(2):118-123. Published online February 28, 1983
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A group of 514 newborn infants with gestational ages between 28 weeks and 36 weeks were
studied for the influence of pronolonged rupture of amniotic membranes and maternal hype-
rtension. during pregnancy on. the incidence of Idiopathic Respiratory Distress Syndrome
(IRDS). The incidence of IRDS in. complicated pregnancy is that significantly lower than in the
control groups. (8.9% vs 18.8%, p<0.05) The occurence of... |
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- A Clinical Study of Mother's Understanding About Children's Fever.
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Seung Joo Lee
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Clin Exp Pediatr. 1982;25(8):791-799. Published online August 31, 1982
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One hundred mothers bringing their children to a pediatric outpatient deparment of Ewha Womans University Hospital were surveyed about their understanding of fever and method of fever therapy. Most mothers(91%) were unduly worried about low to moderate grade fever with the temperature of 39degrees C or less. They didn't know the thermoregulatory mechanism and thought that fever can rise to... |
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- Early Neonatal Mortality Rate(II) : Obstetric Factors.
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Hae Seong Kim, So Kyung Park, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1982;25(6):584-592. Published online June 30, 1982
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The purpose of this study is to estimate early neonatal mortality rate in relation to obstetric factors. The early neonatal mortality rate was estimated on live births with a gestational period more than 28 weeks who died during the first 7 days of life in Ewha Womans University Hospital fro-m Jan. 1974 to Dec. 1978. During this period, there were... |
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- Case Report
- A Case of D1-Trisomy Syndrome.
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Soon Hee Choi, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1981;24(10):968-972. Published online October 15, 1981
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One cases of D1-Trisomy Syndrome which was confirmed by chromosome study at Ewha Womans University Hospital is presented. The premature female infant was delivered spontaneously at 36 1/2 weeks of gestation at Ewha Womans University. The family and antenatal history were not remarkable except ingestion of some kinds of antibiotics and anti-inflammatory drugs during the first trimester. On physical examination... |
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- Original Article
- A Clinical Statistics of Meconium-Stained Baby.
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Choong Hee Kim, Soon Hee Choi, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1981;24(10):950-956. Published online October 15, 1981
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Clinical study on meconium-stained babies among 6190 newborn's delivered at EWHA Womans University Hospital in 5-year period from January 1973 to December 1977 was. The results are summarized as follows: 1) The incidence of meconium staining was 10.87% in total 6190 newborns. 2) There was a tendency of increasing incidence of meconium staining in babies with higher birth weights and... |
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- Early Neonatal Mortality Rate; Neonatal Factors.
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Mee Kyung Park, Choong Hee Kim, Seung Joo Lee, Keun Lee
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Clin Exp Pediatr. 1981;24(10):920-927. Published online October 15, 1981
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In 8218 newborns who were born in Ewha Womans University Hospital during the period from January, 1974 to December, 1978, the authors investigated the mortality rate within 7 days after birth and studied the factors associated with it. The results are as follows; 1. The early neonatal mortality rate was, in average, 15.5 among 1000 live newborns. 2. The mortality... |
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- Clinicopathologic Study of the Nephrotic Syndrome in Children.
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Seung Joo Lee
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Clin Exp Pediatr. 1977;20(12):943-952. Published online December 31, 1977
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This study is aimed to evaluate the clinicopathologic correlation and responsiveness to steroid therapy of individual glomerular morphology. So, percutaneous renal biopsy was performed in every nine patient with nephrotic syndrome which developed in the abscence of any underlying systemic disease, and it is possible to classify idiopathic nephrotic syndrome into several well defined groups of clinicopathologic entities. Of 9... |
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- The Effect and Complication of Longterm Use of Corticosteroid in Children
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Seung Joo Lee, Hae Sook Kwon, Esook Oh, Keun Chan Sohn
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Clin Exp Pediatr. 1976;19(9):660-667. Published online September 30, 1976
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Since the demonstration of corticosteroid in 1949, there has been very widespread employment with optimism due to its dramatic effect in many patients suffering from nephrotic syndrome and rheumatoid arthritis, etc. But with increasing experiences of this regimen, seriaus side effects have been noted with longterm use.
The effects and various side effects were observed in 92 patients of childhood nephrotic... |
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- Clinical Observation on Cerebrospinal fluid Lactic Dehydrogenase Activity.
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Seung Joo Lee, Hyung Ki Ko, ESook Oh, Don Hee Ahn, Keun Chan Sohn
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Clin Exp Pediatr. 1976;19(12):922-929. Published online December 31, 1976
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Cerebrospinal fluid lactic dehydrogenase activities with other usual laboratory tests were determined in 131 patients including 48 cases of control group with non-CNS disease and 83 cases of various CNS diseases. Mean value of LDH activity in control group (excluding newborn infants) was 31. 7 unit and in 8 control newborn infants was 54 unit. High levels of CSF LDH... |
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