Journal of the Korean Pediatric Society 1987;30(1):17-25.
Published online January 31, 1987.
Sodium Homeostasis by Neonatal Kidney.
Seung Joo Lee
Dept, of Pediatrics, Ewha Womans University
신생아 신기능이 생후 Na 균형에 미치는 영향 : 재태연령과 생후연령에 따른 변화
이화대학교 의과대학 소아과학교실
Sodium homeostasis by neonatal kidney is important during the postnatal adaptation of body fluid. It is mainly dependent to renal function which was differently maturated by gestational and postnatal ages. I studied the postnatal changes of daily Na intake, urine Na, Na balance, FEN a and Serum Na concentration in neonates with different gestational age. In this study, I demonstrated that more increased urinary Na excretion, higher percentage of FENa, more severe and persistent negative Na balance with subsequent hyponatremia develop in group I, preterm infants bom before the 34th gestational weeks, compared to full term infants. Special attention must be paid in very premature with more limited renal tubular reabsorptive function by structural immaturity. Na supplementation is suggested in this very premature by monitoring of urine Na and serum Na concentration until the appropriate positive Na balance for optimal growth is achieved.
Key Words: Na homeostasis, Na balance, FENa, Hyponatremia.

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