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Mi Hyeon Gang

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Clinical Note

Neonatology (Perinatology)

Secondary renal tubular dysgenesis in a newborn exposed to angiotensin Ⅱ receptor antagonist during gestation

Mi Hyeon Gang, Yong Wook Lee, Mea-young Chang

Clin Exp Pediatr. 2021;64(3):136-138. Published online July 21, 2020

Web of Science 4 Crossref 6

Question: The use of renin-angiotensin system (RAS) blockers during pregnancy causes lethal neonatal complications.
Finding: A neonate, whose mother took a RAS blocker during pregnancy, was diagnosed with renal tubular dysgenesis. He presented with respiratory failure, severe refractory hypotension, and anuria requiring continuous dialysis.
Meaning: Physicians should consider any degree of RAS fetopathy in a newborn born to a hypertensive mother who had use of RAS blockers during her pregnancy.

DOI: https://doi.org/10.3345/cep.2020.00752

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