- Case Report
- A case of thanatophoric dysplasia type I with an R248C mutation in the FGFR3 gene
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Eun Jung Noe, Han Wook Yoo, Kwang Nam Kim, So Yeon Lee
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Clin Exp Pediatr. 2010;53(12):1022-1025. Published online December 31, 2010
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Thanatophoric dysplasia (TD) is a short-limb neonatal dwarfism syndrome that is usually lethal in the perinatal period. It is characterized by shortening of the limbs, severely small thorax, large head with a prominent forehead, macrocephaly, curved femur, and flattened vertebral bodies. These malformations result from the mutation in fibroblast growth factor receptor 3 (FGFR-3) gene which is located on the... |
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- Review Article
- Treatment of juvenile rheumatoid arthritis
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Kwang Nam Kim
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Clin Exp Pediatr. 2010;53(11):936-941. Published online November 30, 2010
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The systematic approach to pharmacologic treatment is typically to begin with the safest, simplest, and most conservative measures. It has been realized that the more rapidly inflammation is under control, the less likely it is that there will be permanent sequelae. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the mainstay of initial treatment for inflammation. In addition, the slow-acting antirheumatic drugs (SAARDs)... |
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- Case Report
- A Case of Subdural Abscess Caused by Morganella morganii
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Eun Young Park, Su Jin Lee, Phil Soo Oh, Kwang Nam Kim, Seung Myung Moon
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Clin Exp Pediatr. 2004;47(9):1024-1027. Published online September 15, 2004
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Morganella morganii, a gram-negative bacillus and part of normal faecal flora, is recognised as a common cause of urinary tract infection. We report a rare case of subdural abscess caused by M. morganii in an infant. It was secondary to purulent meningitis. The patient improved with treatment that consisted of surgical excision and systemic antibiotics. |
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- Original Article
- Clinical Analysis of Acute Respiratory Tract Infections by
Influenza Virus in Children
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Min Kyoung Kwon, Mi Ran Kim, Eun Young Park, Kon Hee Lee, Hae Sun Yoon, Kwang Nam Kim, Kyu Man Lee
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Clin Exp Pediatr. 2002;45(12):1519-1527. Published online December 15, 2002
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Purpose : Although influenza virus is one of the most important causes of acute respiratory tract infections(ARTIs) in children, virus isolation is not popular and there are only a few clinical studies on influenza in Korea. We evaluated the epidemiologic and clinical features of ARTIs by influenza virus in children.
Methods : From February 1995 to August 2001, nasopharyngeal aspirations were... |
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- Case Report
- A Case of Apert's Syndrome with Encephalocele and
Hypogenesis of Corpus Callosum
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Min Kyoung Kwon, Ja Yun Yu, Mi Ran Kim, Kon Hee Lee, Hae Ran Lee, Kwang Nam Kim
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Clin Exp Pediatr. 2001;44(7):832-836. Published online July 15, 2001
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Apert's syndrome(acrocephalosyndactyly) is a rare congenital anomaly that is characterized by the combination of premature fusion of multiple cranial sutures primarily involving the coronal suture and severe symmetrical syndactyly of fingers and toes. Some patients of this syndrome have various abnormalities of the central nervous system. We experienced a case of Apert's syndrome with craniofacial malformations, symmetric syndactyly, occipital encephalocele... |
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- Three Cases of Acute Scrotal Disorders in the Neonate
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Ja Yun Yun, Min Kyoung Kwon, Mi Ran Kim, Kon Hee Lee, Kwang Nam Kim, Ho Hyun Jeong
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Clin Exp Pediatr. 2001;44(7):841-846. Published online July 15, 2001
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Acute scrotal disorders(ASD) in neonates-especially the torsion of testes- are rare, and the clinical presentations are quite different from those of adolescents or adults. The neonates with ASD are generally afebrile and do not show typical symptoms. Early diagnosis and proper treatment of ASD are very important but the differentiation of torsion and orchitis is not easy in neonates. The... |
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- Original Article
- Clinical Features of Acute Scrotum in Children
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Ja Yun Yun, Mi Ran Kim, Kon Hee Lee, Kwang Nam Kim
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Clin Exp Pediatr. 2001;44(12):1424-1431. Published online December 15, 2001
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Purpose : The acute scrotum is a clinical syndrome that is defined as an acute, painful swelling
of the scrotum or its contents. The symptoms and signs of acute scrotum are similar and its
pathognomonic features are rarely detected. This study was performed to find a proper way to
diagnose and treat acute scrotum promptly and correctly.
Methods : From January 1990 through December... |
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- Brain Magnetic Resonance Imaging(MRI) in Neurologic Disorders of Children
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Jin Hee Yun, Jae Guk Cha, Ki Sic Min, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo, Ho Chul Kim
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Clin Exp Pediatr. 1995;38(8):1132-1140. Published online August 15, 1995
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Purpose : This study was performed to be helpful in early diagnosis and treatment of the children with neurologic disorders.
Methods : One hundred and eighty-five pediatric patients with neurologic disorder were studied from May 1991 to March 1994, ranging in age from neonate to 15 years old. All patients were imaged with MRI. We observed age and sex distribution, frequency... |
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- Prophylactic Effect of Diazepam to Prevent Recurrent Febrile Seiz
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Seung Eun Choi, Ki Sik Min, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo
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Clin Exp Pediatr. 1995;38(5):685-691. Published online May 15, 1995
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Purpose : The purpose of this study was to investigate efficacy of shortterm diazepam prophylaxis in recurrent febrile seizure.
Methods : A total of 107 children admitted to the department of pediatrics, Kangdong Sacred Heart Hospital, Ballym University from 1 July 1991 to 31 December 1992, with their first or recurrent febrile seizures(one or two times), were entered in the study,... |
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- Case Report
- A Case of Right Lung Agenesis
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Seung Hyun Seo, Yu Sub Shin, Ki Sik Min, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo
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Clin Exp Pediatr. 1992;35(3):428-433. Published online March 15, 1992
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Lung agenesis is the very rare disease which is defined as total absence of the pulmonary parenchyma, its vascular supporting structure, and bronchi beyond the carina. In many cases, there are coexisting anomalies involving the skeletal, cardiovascular, gastrointestinal, and genitourinary systems. Also, severe respiratory infections are common in infancy and may lead to pneumonia and death. When associated anomalies are... |
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- Original Article
- Clincal Observations on Human Rotavirus (HRV) Gastroenteritis
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Seung Ryong Han, Seung Hyun Seo, Ki Sik Min, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo
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Clin Exp Pediatr. 1992;35(2):226-233. Published online February 15, 1992
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Clinical observations were made on 787 patients who were admitted to pediatric department of Kangdong Sacred Heart hospital because of watery diarrhea and vomiting between Jan. 1987 and Dec, 1989.
ELISA study was done to detect HRV antigen for all patients.
The results were as follows :
1) HRV antigen was detected in 492 patients (62.5%) by ELISA among 787 patients with watery... |
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- Intracranial hemorrhage in the prematurity and small for gestational age an attempt of clinico-ultrasonographic correlation.
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Kwang Sup Kim, You Seop Shin, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo, Hyo Keun Lim
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Clin Exp Pediatr. 1991;34(1):49-56. Published online January 31, 1991
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To evaluate the correlation between clinical and ultrasonographic findings, 79 consecutive brain
ultrasonographic examinations were performed in the 50 prematurity and 29 SGA.
Statistical significance was not detected about sex ratio, hemoglobin and hematocrit, Apgar score
and maternal age between the prematurity and SGA. Incidence of ICH was 66% in the prematurity
and 48% in the SGA.
According to Papile’s grading system, Grade 1 was... |
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- A Study of Ultrasonographic findings in Children with Gastrointestinal Symptoms.
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Dong Lag Choi, Kwang Sup Kim, Jong Wang Kim, Duk Kyu Kim, Kwang Nam Kim, Ki Yang Ryoo, Hyo Keun Lim
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Clin Exp Pediatr. 1990;33(11):1548-1556. Published online November 30, 1990
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We analyzed retrospectively the sonographic findings in 162 children who accompanied with gastrointes-
tinal symptoms and performed the comparative analysis of the clinico-pathologic findings to sonographic
findings from Jan. 1988 to July 1989. The most frequent symptom was abdominal pain (79.6%). The clinical
impression prior to ultrasonography were acute appendicitis (34%), mesenteric lymphadenitis (10.4%), hyper-
trophic pyloric stenosis (5%) in order. Positive cases in... |
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- Case Report
- A case of Sacrococcygeal Teratoma.
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Seung Jae Yang, Kwang Nam Kim, In Joon Seol, Soo Jee Moon, Keun Soo Lee
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Clin Exp Pediatr. 1986;29(5):564-569. Published online May 31, 1986
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We exprienced a case of sacrococcygeal teratoma in newborn girl with massive intraabdominalfextensioii and small caudal mass, which is relative rare.
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- A case of Congenital Nephrotic Syndrome.
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Kwang Nam Kim, Kwang Hyun Kim, In Joo Seol, Ha Baik Lee, Chong Moo Park
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Clin Exp Pediatr. 1985;28(9):931-935. Published online September 30, 1985
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The congenital nephrotic syndrome is characterized by large placenta, low birth weight, early clinical findings, delayed growth and development and resistance to treatment. Authors experienced a case of characteristic of congenital nephrotic syndrome in a girl, who was admitted to the Pediatric Department of HUH at 28 days of age because of generalized edema, abdominal distension with vomiting and diarrhea.... |
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- Original Article
- Clinical Studies of Anaphylactoid Purpura in Childhood.
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Kwang Hyun Kim, Kwang Nam Kim, Ha Baik Lee, Hang Lee
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Clin Exp Pediatr. 1985;28(6):545-554. Published online June 30, 1985
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Anaphylactoid purpura or Henoch-Schonlein purpura is a common pediatric disease presenting most frequently with purpura, and occasionally with gastrointestinal and joint manifestations, and has been known to present pathologically with diffuse vasculitis involving small blood vessles in many organs. Clinical manifestations and laboratory findings were observed and analyzed in 110 cases with anaphylactoid purpura hospitalized at Hanyang University Hospital during... |
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- Clinical Study of Idiopathic Thrombocytopenic Purpura in Children.
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Kwang Nam Kim, Sang Hee Cho, Je Hoon Shin, Woo Gill Lee
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Clin Exp Pediatr. 1985;28(3):251-257. Published online March 31, 1985
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The authors studied 26 cases with idiopathic thrombocytopenic purpura who were admitted to Department of Pediatrics Hanyang University Hospital. The results were as follows: 1)The peak incidence of age was 5 to 7 years old. Male to female ratio was 2.7 : 1 which showed: slight male preponderance. 2)lThe most prevalent seasons were spring and summer. In both seasons, the... |
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- Clinical Studies on Childhood Bronchial Asthma.
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Kwang Nam Kim, Soo Yup Lee, Ha Baik Lee, Kyu Hwan Lee, Woo Gill Lee, Keun Soo Lee
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Clin Exp Pediatr. 1985;28(10):997-1006. Published online October 31, 1985
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The results of clinical observation and hematologic findings on 120 cases with bronchial asthma who were admitted to the department of pediatrics, Hanyang University Hospital from Mar. 1984 to Feb. 1985 were as followings: 1)As to the age distribution, 80% of total cases were under 7-year-old and the sex ratio was 2.6 . 1 with male predominance. 2)As to the... |
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- Clinical Study of the Paranasal Sinusitis in Childhood.
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Young Suk Song, Kwang Nam Kim, Gwi Jong Choi, Chong Moo Park, Hyung Seok Lee
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Clin Exp Pediatr. 1984;27(9):877-882. Published online September 30, 1984
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Sinusitis is generally considered to occur frequency to children. However, objective diagnostic procedures to establish the etiology of the disease have not been used ordinarily because of the growth and development of paranasal sinus in childhood. Due to these difficulties, adequate information concerning the incidence of the disease and its optimal therapy has not been available. This retrospective study was... |
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- Case Report
- Adrenogenital Syndrome with Congenital Adrenal Hyperplasia.
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Myoung Sung Moon, Kwang Nam Kim, Woo Gill Lee
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Clin Exp Pediatr. 1984;27(5):511-515. Published online May 31, 1984
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When the adrenogenital syndrome is associated with congenital adrenal hyperplasia, it is caused by an inborn defect in the biosynthesis of adrenal corticoids. Especially, infant with congenital adrenal hyperplasia caused by a 21-hydroxylation. defect in steroidogenesis often present with salt-losing crisis, hyponatremia and dehydration.
Vomiting is prominent and disturbances in cardiac rate and rhythm may occur. Without treatment, collapse and death... |
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