- Case Report
- Toxic epidermal necrolysis induced by lamotrigine treatment in a child
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Youngsuk Yi, Jeong Ho Lee, Eun Sook Suh
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Clin Exp Pediatr. 2014;57(3):153-156. Published online March 31, 2014
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Toxic epidermal necrolysis is an unpredictable and severe adverse drug reaction. In toxic epidermal necrolysis, epidermal damage appears to result from keratinocyte apoptosis. This condition is triggered by many factors, principally drugs such as antiepileptic medications, antibiotics (particularly sulfonamide), nonsteroidal anti-inflammatory drugs, allopurinol, and nevirapine. Lamotrigine has been reported potentially cause serious cutaneous reactions, and concomitant use of valproic acid... |
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- Original Article
- Characteristics of thyroid nodules in infant with congenital hypothyroidism
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Seo Young Youn, Jeong Ho Lee, Yun-Woo Chang, Dong Hwan Lee
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Clin Exp Pediatr. 2014;57(2):85-90. Published online February 24, 2014
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Purpose This study aimed to assess the characteristics of thyroid nodules among infants diagnosed with congenital hypothyroidism. MethodsA retrospective study of 660 infants (374 males, 286 females) diagnosed with congenital hypothyroidism was carried out at the Pediatric Endocrine Clinic in Soonchunhyang University Hospital, Korea, between May 2003 and February 2013. The average age at diagnosis was 1.16±1.68 months. ResultsOf the 28 patients (4.2%)... |
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- Colonic Transit Time in Chronic Constipated Patients
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Je Eun Choi, Im Jeong Choi, Jung A Lee, Sung Mi Kim, Jin Hwa Jeong, Jeong Ho Lee
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Clin Exp Pediatr. 2001;44(7):752-757. Published online July 15, 2001
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Purpose : In most instances, constipation is considered as idiopathic or functional. The total colonic transit time, traced by radio-opaque markers, makes possible the identification of the colon segment that has the motility alteration that causes constipation. We measured the total and segmental colonic transit time in children with chronic idiopathic constipation and compared the results with those without constipation... |
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- The Optimum Dose of Oral Diazepam to Reduce Seizure
Attack in Febrile Seizure Patients During Febrile Illness
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Im Jeong Choi, Je Eun Choi, Jung A Lee, Pil Ju Jeong, Sung Mi Kim, Jin Hwa Jeong, Jeong Ho Lee
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Clin Exp Pediatr. 2001;44(6):677-682. Published online June 15, 2001
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Purpose : Febrile seizure is the most common type of seizure affecting 3-4% of children. The recurrence rate of febrile seizure is approximately 33%. About 16% of children with a febrile seizure during the febrile illness have a recurrent seizure attack within 24 hours. This study aimed to investigate the optimum dose of diazepam to reduce the recurrence of febrile... |
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- Case Report
- A Case of Corpus Callosum Agenesis with Ileal Atresia and Duplication
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Kyoung A Chun, Young Dae Ham, Jin Hwa Jeong, Jeong Ho Lee, Hye Suk Kim
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Clin Exp Pediatr. 2000;43(8):1127-1131. Published online August 15, 2000
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Agenesis of corpus callosum occurs sporadically and may be transmitted as sex-linked, or autosomal-dominant or recessive traits. It has been associated with different syndromes. Clinical pictures vary from severe intellectual and neurologic abnormalities to asymptomatic and normaly intelligent cases. Agenesis of corpus callosum may occur alone, but it is more frequently associated with a high incidence of other anomalies. We... |
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- A Case of Primary Hypomagnesemia
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Kyoung A Chun, Sung Pil Jang, Young Dae Ham, Jin Hwa Jeong, Jeong Ho Lee
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Clin Exp Pediatr. 2000;43(8):1153-1156. Published online August 15, 2000
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Primary hypomagnesemia is a rare inherited disorder and it is considered to be due to either a defect in the intestinal transport of magnesium or a defect in renal tubular transport. It is important to measure the urinary excretion of magnesium to differentiate the causes of magnesium deficiency. We report here an one-month-old female infant of primary hypomagnesemia who presented... |
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- Original Article
- Association between Tuberculin Responses and Serum IgE
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Pil Ju Jeong, Yong Dae Ham, Jin Hwa Jeong, Jeong Ho Lee
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Clin Exp Pediatr. 2000;43(4):502-505. Published online April 15, 2000
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Purpose : Atopy is a state of allergic response, mediated by IgE, to common environmental allergens. In recent decades, there has been an increase in prevalence of atopic disorders in children in developed countries. The factor associated with the rise of atopy incidence may be declining exposure to some infection opportunities. The aim of this study is to determine if... |
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- Original Article
- C-Reactive Protein and Duration of Antibiotic Therapy in Neonatal Bacterial Infection
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Jae Il Yoo, Jin Hwa Jeong, Jeong Ho Lee, Jong Dae Cho
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Clin Exp Pediatr. 1998;41(7):901-908. Published online July 15, 1998
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Purpose : To determine whether C-reactive protein(CRP) can be used as a parameter to assess the safety of discontinuing antibiotic therapy and allows a shorter course of therapy in neonates treated for suspected bacterial infection.
Methods : We have experienced 193 cases of suspected neonatal bacterial infection at Pusan Maryknoll Hospital. CRP levels were measured daily by immunonephelometry. Infants with initial... |
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- Case Report
- A Case of Congenital Factor Ⅶ Deficiency Associated with Intraventricular Hemorrhage and Hydrocephalus
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Hyoung Jun Kim, Jin Hwa Jung, Jeong Ho Lee, Jong Dae Jo
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Clin Exp Pediatr. 1998;41(12):1726-1730. Published online December 15, 1998
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Congenital factor Ⅶ deficiency is a rare bleeding disorder with an estimated incidence of 1 in 500,000. It is inherited as an autosomal recessive pattern with variable expression and high penetrance. In severely affected patients, repeated hemarthroses, chronic crippling hemarthropathy, and dangerous hematomas can occur. Other types of hemorrhage include epistaxis, menorrhagia, hematuria, gastrointestinal and gingival bleeding. Fetal cerebral hemorrhage... |
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- Original Article
- Relationship between Chest Radiography and Cell-mediated Immunity in Mycoplasma pneumoniae Pneumonia
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Yong Dae Ham, Jae Il Yoo, Jin Hwa Jeong, Jeong Ho Lee, Jong Dae Cho
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Clin Exp Pediatr. 1998;41(11):1509-1516. Published online November 15, 1998
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Purpose : Mycoplasma pneumoniae pneumonias have been one of the most common causes of lower respiratory tract diseases during childhood. It is suggested that pathologic changes seen in the lung tissues were the histologic expression of the host immune response. The aim of this study was to determine the relationship between the chest radiographic pattern of Mycoplasma pneumoniae pneumonia and... |
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- Immunohistochemical Study of Bcl-2 Oncoprotein Expression in Childhood Non-Hodgkin's Lymphoma
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Sung Mee Kim, Jin Hwa Jung, Jeong Ho Lee, Jong Dae Jo, Young Tak Lim, Do Youn Park, Sun Kyeung Lee
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Clin Exp Pediatr. 1997;40(9):1265-1274. Published online September 15, 1997
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Purpose : The aim of the present study was to assess the clinicopatholgical significance
of Bcl-2 oncoprotein expression in childhood non-Hodgkin' s lymphoma(NHL).
Methods : We have assessed 16 cases of childhood NHL during last 6 years from
1990 to 1995. Bcl-2 oncoprotein expression has been semiquantitatively analyzed in
paraffin sections from 16 cases of childhood NHL with 39 control cases of adult NHL.
The... |
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- Case Report
- A Case of Double Duodenal Web Associated with Peptic Ulcer
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Sun Young Park, Jin Hwa Jung, Jeong Ho Lee, Jong Dae Jo
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Clin Exp Pediatr. 1997;40(9):1319-1324. Published online September 15, 1997
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Duodenal web is a very rare congenital anomaly which usually causes clinical features
of intestinal obstruction from early infancy. It shows characteristic findings in the
radiologic contrast study or endoscopy. But in the cases with large openings, preoperative
diagnosis of web is difficult and often is overlooked until adolescence or adulthood
because of delayed onset of symptoms. Duodenal web is usually single near the... |
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- Three Cases of Rotor Syndrome in Monozygotic Twin Brothers and Their Sister
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Jin Hwa Jung, Jeong Ho Lee, Yong Sub Kim, Jong Dae Jo
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Clin Exp Pediatr. 1995;38(9):1270-1275. Published online September 15, 1995
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We recently experienced three cases of Rotor syndrome in monozygotic twin brothers and their elder sister.
The only clinical manifestation was persisting mild jaundice for several years. In all three cases serum bilirubin, mainly of direct reacting was increased with normal liver function and normal hepatic histology without pigmentation by needle liver biopsy. Indocyanine green test showed marked serum retention after... |
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- Original Article
- Circumcision, Neonates, Pain sensation
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In Rok Do, Jeong Ho Lee, Yong Sub Kim, Jong Dae Jo
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Clin Exp Pediatr. 1995;38(10):1324-1328. Published online October 15, 1995
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Purpose : Routine neonatal circumcision has widely performed without anesthesia under the assumption that the penis of neonates does not yet have functioning pain sensory nerve endings at this early stage of development, and has decreased the incidence of neonatal urinary tract infection. This study was performed to evaluate whether neonates recognize pain during opertion of circumcision without anesthasia.
Methods :... |
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