- Original Article
- Ototoxicity in children receiving cisplatin chemotherapy
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Hee Jin Jang, Hyung Rae Cho, Jae Hee Lee, Kun Yuk Bae, Jong Jin Seo, Hyung Nam Moon, Ho Joon Im
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Clin Exp Pediatr. 2010;53(2):210-214. Published online February 15, 2010
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Purpose : Cisplatin is highly effective for the treatment of solid tumors in children. However, the clinical use of cisplatin is limited by its ototoxicity. The aim of this study was to evaluate the ototoxicity in children treated with cisplatin.
Methods : We performed a single institution retrospective analysis of pediatric oncology patients who received cisplatin therapy between January 2001 and... |
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- QT Dispersion after Chemotherapy with Anthracyclines in Children
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Jae Kon Ko, Young Hwee Kim, In Sook Park, Jong Jin Seo, Hyung Nam Moon
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Clin Exp Pediatr. 2001;44(8):908-915. Published online August 15, 2001
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Purpose : Anthracycline induced cardiotoxicity is well known and its pathology is characterized by localized myocardial cell necrosis and myocardial fibrosis. The variability in QT interval duration amongst the different leads of the standard 12-lead ECG(QT dispersion) is considered to reflect inhomogenous repolarization of the myocardium. The aim of this study was to assess the effects of anthracycline on cardiac... |
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- Living Related Donor Liver Transplantation in Children : Indication and Clinical Outcome
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Kyung Mo Kim, Sung gyu Lee, Young Joo Lee, Kwang Min Park, Seong Chul Kim, Hoon Bae Chun, Eun Sil Yoo, Sang Hoon Han, Kyung Suk Ko, Mon Gyu Lee, Kyu Taek Choi, Jae Kon Ko, Hyung Nam Moon
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Clin Exp Pediatr. 1998;41(5):622-632. Published online May 15, 1998
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- Effect of Recombinant Human Erythropoietin on the Anemia of Premature Infants
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Young Ah Lee, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1996;39(5):631-640. Published online May 15, 1996
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Purpose : To determine whether the prophylactic treatment with recombinant human
erythropoietin(rHuEPO) for the anemia of prematurity would reduce the need for blood
transfusions.
Methods : We randomly assigned 17 premature infants to therHuEPO group and the
control group. For the rHuEPO group (n=9, birth weight=1210¡¾156 g, gestational
age=31.7¡¾1.9wk), rHuEPO (400U/kg) was given three times a week for 4 weeks, plus
iron (8 mg/kg/day) and vitamin... |
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- The Study of Distribution of HI Antibody Titers Aganist
Japanese Encephalitis Virus Among Children in Seoul
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Jin A Kim, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Hae Wol Cho
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Clin Exp Pediatr. 1996;39(2):230-237. Published online February 15, 1996
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Purpose : Incidence of Japanese encephalitis has been markedly decreased, but this disease is known to be high and lethal in the young age group. This study was designed to find out the HI antibody titers and associated factors of Japanese encephalitis of children in Seoul, and to establish the plan of vaccination.
Methods : The survey was conducted from the... |
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- Case Report
- A Case Report : Ganciclovir Therapy of Cytomegalovirus Pneumonitis
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Jee-Yeon Min, Soo-Jong Hong, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1996;39(1):142-147. Published online January 15, 1996
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Ganciclovir is an antiviral agent that is effective for cytomegalovirus (CMV) infection in immunocompromised hosts. But the benefits of treatment for the congenital CMV diseases are still controversial. Cytomegalovirus pneumonitis is very rare. And so, a few cases of ganciclovir therapy in CMV pneumonitis were reported.
We experienced a case of a 7 month-old male infant with prolonged pneumonitis and
respiratory difficulty... |
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- Original Article
- Clinical and Histologic Changes in Children with Chronic Hepatitis B Virus Infection after Alpha Interferon Therapy
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Kyung Mo Kim, Soo Jong Hong, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Joo Ryoung Huh
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Clin Exp Pediatr. 1995;38(9):1232-1241. Published online September 15, 1995
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Purpose : Several trials in children for chronic hepatitis B have shown the efficacy of alpha interferon in eliminating hepatitis B virus replication, accompanied by an improvement in the liver cell damage. But reports about the alpha interferon therapy are rare in Korean children and there is no report about histologic changes even with adult. So we tried to... |
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- Prevalence of Epstein-Barr Virus (EBV) Antibody in Korean Children
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Sei Ho Oh, Young Ah Lee, Woong Young Moon, Tae Sun Won, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
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Clin Exp Pediatr. 1994;37(6):804-811. Published online June 15, 1994
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Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15... |
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- Infectious Mononucleosis in Children
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Woong Young Moon, Sei Ho Oh, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
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Clin Exp Pediatr. 1994;37(6):822-831. Published online June 15, 1994
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We reviewed th eclinical findings of infectious mononucleosis and performed Epstein-Barr virus (EBV) serologic antibody tests in infectious mononuleosis and healthy group. One group was 18 cases of children, diagnosed as infectious mononucleosis who had been admitted to the department of Pediatrics. Asan Medical Center for two years and eight months. From November, 1989 to June, 1992. Another group was... |
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- Case Report
- A Case of Rett Syndrome Observed with Video-EEG Monitoring
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Hyun Mi Kim, Young Ah Lee, TaecSung Ko, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1994;37(5):718-725. Published online May 15, 1994
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Rett syndrome is progressive neurodegenerative disorder in female patients, characterized by autistic behavior, mental retardation, loss of purposeful hand skills, sterotypic hand movement, breathing dysfunction, severely impaired language, ataxia, and seizure. The diagnosis of Rett syndrome is based on its characteristic clinical manifestation and course. The electroencephalographic(EEG) findings of Rett syndrome are nonspecific, but a progressive deteriorationin the EEF, characterized... |
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- Original Article
- Hand, Foot and Mouth Disease Associated with the Aseptic Meningitis in Seoul, 1990
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Young Ah Lee, Sei Ho Oh, Soo Jong Hong, Young Hwue Kim, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1993;36(6):842-849. Published online June 15, 1993
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We performed clinical and virological studies on 79 children with hand, foot and mouth disease(HFMD) who had been admitted or visited to the department of Pediatrics, Asan Medical Center from February to August, 1990.
The results were as follows;
1) There were total of 79 cases with hand, foot and mouth disease during this period. The aseptic meningitis was combined in 18cases(22.8%)
2)... |
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- A Clinical Study on Aseptic Meningitis Combined with Polio-Like Paralysis
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Woong Young Moon, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Chul Suh, Si Joon Yu, In Young Seong, Young Min Ahn
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Clin Exp Pediatr. 1993;36(4):485-494. Published online April 15, 1993
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We clinically reviewed four patients who were suffering from aseptic meningitis combined with polio-like paralysis and performed radiological, neurological and virological studies on them.
Three patients were admitted to the department of Pediatrics. Asan Medical Center from March to August 1990, and one patient was admitted to the department of Pediatrics, Kangnam General Hospital.
The results were as follows:
1) During the period... |
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- Aseptic Meningitis in 1991 - isolation of causative agent -
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Yoon Ah Park, Eun Young Cho, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1993;36(4):506-511. Published online April 15, 1993
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To know the causative agent of asptic meningitis, we performed blood and cerebrospinal fluid study on 24 children who had been admitted to the department of Pediatrics, Asan Medical Reference Laboratory, Japan.
The most of the patients were young infants, and 15 cases of them were under 3 months of age.
The male to female ratio was 1:1.4.
We observed the main symptoms... |
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- Influenza Epidemic in the Pediatric Patients in Seoul 1991
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Hyun Mi Kim, Se Ho Oh, Eun Young Cho, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Young Suhn Kim, Kee Duk Park
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Clin Exp Pediatr. 1993;36(3):379-385. Published online March 15, 1993
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Influenza virus culture was performed in 149 patients with influenza-like illness who were admitted or visited to the Department of Pediatrics, Asan Medical Center from january 1991 to March,1991.
The results were as follows :
1) Of the total 149 patients, influenza virus were isolated in the 15 cases.
: 15 isolates were characterized by the WHO Collaborating Center for influenza : 7... |
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- Case Report
- A Case of Acute Disseminated Encephalomyelitis -Magnetic Resonance Imaging Findings-
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Soo Jong Hong, Hyung Nam Moon
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Clin Exp Pediatr. 1992;35(7):1019-1025. Published online July 15, 1992
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Acute disseminated encephalomyelitis(ADEM) is an acute inflammatory demyelinating disease of the central nervous system. We experienced a case of ADEM in an 8 year-old boy who showed headache, vomiting, weakness of lower extremities and visual disturbance. Brain magnetic resonance imaging demonstrated multiple patch high signal intensity in both optic nerves, both thalamus, splenium of corpus callosum, and subcortical white matter... |
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- Original Article
- Hepatic Rickets in Infancy with Neonatal Hepatitis
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Mi Koo Kang, Eun Young Cho, Soo Jong Hong, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1992;35(4):527-533. Published online April 15, 1992
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We had treated a hepatic rickets in 6 infants with neonatal hepatitis from June 1989 to August 1990 at Asan Medical Center.
The results were as follows
1) Age of 6 patients were below 4 months and 4 patients were male, 2 patients were female.
2) The clinical findings were hepatosplenomegaly(5 cases), jaundice(4 cases), craniotabes (4 cases), failure to thrive(2 cases), hypocalcemiac seizure(2... |
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- Treatment of Kawasaki Disease with Single High-dose Intravenous Gammaglobulin
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Mi Koo Kang, Eun Young Cho, Young Hwue Kim, Ki Soo Kim, Young Seo Park, In Sook Park, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1992;35(3):342-348. Published online March 15, 1992
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Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children under 5 years of age. Coronary aneurysms are the most serious complications and 15-20% of patient develop coronary aneurysm.
We studied 50 children who wre diagnosed as Kawasaki disease and treated simultaneously with single high-dose gammaglobulin (2 gm/kg/day) and aspirin at Asan Medical Canter... |
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- Epidemics of aseptic meningitis in Seoul area during 1989-90.
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Eun young Cho, Mi Koo Kang, Soo Jong Hong, Ki Soo Kim, Young Seo Park, In Sook Park, Hyung Nam Moon, Chang Yee Hong
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Clin Exp Pediatr. 1991;34(11):1565-1572. Published online November 30, 1991
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We performed clinical and virological studies on 200 children with aseptic meningitis who had been
admitted to the department of Pediatrics, Asan Medical Center from June, 1989 to August, 1990.
The results were as follows;
1) There were total of 236 meningitis cases during this period, 13(5.5%) with bacterial meningitis,
3(1%) with tuberculous meningitis, 220(93.2%) with aseptic meningitis. Am이lg aseptic meningitis,
20(8.5%) were mumps meningitis.
2) Aseptic meningitis... |
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