Clinical and Experimental Pediatrics

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Hae Young Go (Go HY)

1 Article

Original Article

Expression of nitric oxide synthase isoforms and N-methyl-D-aspartate receptor subunits according to transforming growth factor-β1 administration after hypoxic-ischemic brain injury in neonatal rats

Hae Young Go, Eok Su Seo, Woo Taek Kim

Clin Exp Pediatr. 2009;52(5):594-602. Published online May 15, 2009

Purpose : Transforming growth factor (TGF)-β1 reportedly increases neuronal survival by inhibiting the induction of inducible nitric oxide synthase (NOS) in astrocytes and protecting neurons after excitotoxic injury. However, the neuroprotective mechanism of TGF-β1 on hypoxic-ischemic (HI) brain injury in neonatal rats is not clear. The aim of this study was to determine whether TGF-β1 has neuroprotective effects via a...

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