Clinical and Experimental Pediatrics

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Chung-Soon Chang (Chang CS)

1 Article

Original Article

Measurement of Malonate Concentration using Malonyl-CoA Synthetase and its Relationship with Disease

Seung-Kyoo Han, Jeung-Kyu Kim, Seung-Ryeoul Paik, Chung-Soon Chang, Yu-San Kim

Clin Exp Pediatr. 1995;38(9):1167-1175. Published online September 15, 1995

Purpose : Malonate is an effective competitive inhibitor of succinate dehydrogenase isolated from brain and other organs. It has been shown that malonate level is proportional to the growth of fetal rat brain. However, little is known about its biological effects on central nervous system and other organs. In this communication. we have measured malonate levels in neonates and patients...

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