- Original Article
- Birth statistics of high birth weight infants (macrosomia) in Korea
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Byung-Ho Kang, Joo-Young Moon, Sung-Hoon Chung, Yong-Sung Choi, Kyung-Suk Lee, Ji-Young Chang, Chong-Woo Bae
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Clin Exp Pediatr. 2012;55(8):280-285. Published online August 23, 2012
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Purpose The authors analyzed the trend from the birth-related statistics of high birth weight infants (HBWIs) over 50 years in Korea from 1960 to 2010. MethodsWe used 2 data sources, namely, the hospital units (1960's to 1990's) and Statistics Korea (1993 to 2010). The analyses include the incidence of HBWIs, birth weight distribution, sex ratio, and the relationship of HBWI to maternal... |
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- Review Article
- Changes in the neonatal and infant mortality rate and the causes of death in Korea
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Sung-Hoon Chung, Yong-Sung Choi, Chong-Woo Bae
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Clin Exp Pediatr. 2011;54(11):443-455. Published online November 30, 2011
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Neonatal mortality rate (NMR) or infant mortality rate (IMR) are the rate of deaths per 1,000 live births at which babies of either less than four weeks or of one year of age die, respectively. The NMR and IMR are commonly accepted as a measure of the general health and wellbeing of a population. Korea's NMR and IMR fell significantly... |
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- Original Article
- A report on operating a nationwide human milk bank in Korea
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Kang Hoon Song, Yoo Min Lee, Ji Young Chang, Eun Young Park, Sung Ae Park, Nam Kyu Cho, Chong-Woo Bae
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Clin Exp Pediatr. 2010;53(4):488-494. Published online April 15, 2010
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Purpose : A human milk bank collects, processes, eliminates, and stores breast milk from donors and provides breast milk
to those in need. The authors hereby present the experiences and the objective lessons obtained through operating a nationwide
human milk bank over a period of 2 years.
Methods : The characteristics of the donors and the recipients and the amounts of breast milk... |
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- Multiple births conceived by assisted reproductive technology in Korea
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Young Sil Park, Sun Hee Choi, Kye Shik Shim, Ji Young Chang, Won Ho Hahn, Yong Sung Choi, Chong-Woo Bae
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Clin Exp Pediatr. 2010;53(10):880-885. Published online October 31, 2010
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Purpose The recent trends of multiple births (MBs) conceived by assisted reproductive technology (ART) in Korea were analyzed as well as the relationship with maternal age, especially advanced maternal age. MethodsData were obtained from the Korean Statistical Information Service and annual ART reports from the ART committee of the Korean Society of Obstetrics and Gynecology. ResultsMBs increased from the early 1990s; there was... |
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- Review Article
- Ethical considerations in publication of medical papers
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Chong-Woo Bae
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Clin Exp Pediatr. 2008;51(5):447-451. Published online May 15, 2008
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It is fair to say that there are many ethical issues concerning the publication of medical papers. To define the best practice in the ethics of scientific publishing and a proper understanding of appropriate reporting in medical papers, this review should be useful for authors dealing with ethical issues which involve the protection of human and animal rights, the protection... |
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- Original Article
- Surfactant Therapy for Neonatal Respiratory Distress Syndrome : Experience in Korea Over 15 Years
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Chong-Woo Bae, Young-Min Kim
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Clin Exp Pediatr. 2004;47(9):940-948. Published online September 15, 2004
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Purpose : Surfactant replacement therapy in neonates with respiratory distress syndrome(RDS) has been used in Korea since 1990. We undertook a collective study of trials from multi-hospitals to evaluate results of neonates with RDS who were treated with surfactant during the past 15 years in Korea(Period I, P-I, 1990-91; Period II, P-II, 1996; Period-III, P-III; 2002).
Methods : There were 60... |
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- Original Article
- Correlation between Chest Radiographic Findings and Respiratory Indices in Neonates with Respiratory Distress Syndrome
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Yong-Hwan Chung, Youn-Jin Park, Chong-Woo Bae, Dong-Wook Sung
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Clin Exp Pediatr. 2003;46(7):655-660. Published online July 15, 2003
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Purpose : The relationship between chest X-ray findings and respiratory indices, including the arterial-alveolar oxygen partial pressure ratio(a/APO2) and the ventilatory index(VI), indicators of the clinical respiratory status in neonates with respiratory distress syndrome(RDS), was examined in the present study.
Methods : The records of 50 neonates, randomly chosen from 174 neonates treated with pulmonary surfactant(PS) in the Neonatal Intensive Care... |
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- Case Report
- A Case of Hemolytic Disease in a Newborn Due to Anti-Jkb
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Dong-Kyun Park, Young-Min Kim, Chong-Woo Bae, Yong-Mook Choi, Woo-In Lee
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Clin Exp Pediatr. 2003;46(7):718-721. Published online July 15, 2003
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The isoimmune hemolytic disease of newborn due to the incompatibility of minor blood groups is characterized by progressive neonatal hyperbilirubinemia and anemia caused by the IgG antibody transmitted from the mother to the fetus. Recently we had a case of hemolytic disease in a newborn due to anti-Jkb. There were no ABO and Rh(D) incompatibilities between mother and baby. The... |
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- Original Article
- Comparison of Clinical Courses According to the Existence of
Patent Ductus Arteriosus in Respiratory Distress Syndrome
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Ju Hee Seong, Hyeon Joo Lee, Hyun Kee Hong, Chong-Woo Bae, Yong-Mook Choi
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Clin Exp Pediatr. 2003;46(11):1080-1084. Published online November 15, 2003
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Purpose : To compare perinatal characteristics, clinical courses, and overall morbidity between respiratory distress syndrome(RDS) with patent ductus arteriosus(PDA) and RDS without PDA in neonates.
Methods : Eighty-three neonates who were diagnosed and treated for RDS in the neonatal intensive care unit(NICU) from Jan. 2000 to Dec. 2002 were included in this study. RDS was complicated with PDA(group A) in... |
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- A Study of Surface Physical Properties of New Surfactant Using Synthetic Peptides of Surfactant Protein-B
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Chong-Woo Bae, Yong-Mook Choi, Joo Hyun Kang, Sang-Chul Lee, Kil Lyong Kim, Kyung-Soo Hahm
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Clin Exp Pediatr. 2000;43(8):1059-1067. Published online August 15, 2000
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Purpose : To produce a new generation of artificial pulmonary surfactant(PS), surfactant protein
(SP)-B from human PSwas isolated, and the amino acid sequences of these proteins were
studied. Artificial peptides of human SP-B were synthesized. New artificial PS preparations which
were composed of phospholopids and two artificial synthetic SP-B peptides were made, and the
surface physical properties of these new PS preparations were tested.
Methods... |
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- Analysis of Risk Factors of Readmission to Hospital for Pediatric Asthma
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Kyung Lim Yoon, Young Ho Rah, Chong-Woo Bae, Sa Jun Chung
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Clin Exp Pediatr. 2000;43(4):556-560. Published online April 15, 2000
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Purpose : The admission rates for pediatric asthma are increasing annually and are partially responsible for the increased rates of readmission. Selections of children with a high-risk of readmission and aggressive treatments of them may improve treatment outcome and cost- effectiveness. The purpose of this study is to evaluate the risk factors affecting readmission in cases of bronchial asthma in... |
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- Clinical Application of Impedance Audiometry in Children with Acute Otitis Media
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Jee Sung Hwang, Sung Do Kim, Young-Ho Rah, Chong-Woo Bae
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Clin Exp Pediatr. 2000;43(11):1446-1450. Published online November 15, 2000
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Purpose : Acute otitis media is one of the most prevalent diseases of childhood and can cause serious complications such as hearing loss. The exact diagnosis is extremely important but may be hard to make because of probabilities of over- and underdiagnosis. We performed impedance audiometry(IA) in routine examinations for acute otitis media and applied it for screening and follow-up... |
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- Original Article
- A Comparative Study of Red Blood Cell Indices and Anemia by Feeding Patterns
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Pill-Jin Shin, Chong-Woo Bae, Yong-Mook Choi
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Clin Exp Pediatr. 1999;42(8):1104-1110. Published online August 15, 1999
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Purpose : Iron-deficiency anemia is the most common nutritional deficiency in young infants. This study was designed to determine feeding patterns in infants, and determine a correlation between feeding patterns and incidence of anemia.
Methods : This study was conducted by taking blood tests (hemoglobin, hematocrit, and red cell indices) by venipuncture with the electronic counters from 221 infants aged 9-12... |
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- Clinicial Observations of Oliguric Acute Renal Failure in Children
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Sung-Soo Lee, Young-Mi Choi, Chong-Woo Bae, Sung-Ho Cha, Byoung-Soo Cho
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Clin Exp Pediatr. 1999;42(10):1419-1425. Published online October 15, 1999
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Purposes : We studied the clinicial findings of oliguric acute renal failure(ARF) developed on admission or during treatment of other diseases.
Methods : We performed a retrospective analysis of medical records of 118 patients with oliguric ARF who had been admitted to Kyunghee University Hospital since January 1988 to December 1997. Diagnostic criteria of oliguric ARF are serum creatinine>1.0mg/dl and urine... |
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- Preparation and in vitro Physical Activities of Crude Natural Surfactant and Artificial Pulmonary Surfactant Containing Synthetic Peptide and Phospholipid Mixtures
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Joo Hyun Kang, Song Yub Shin, Cheol-Young Maeng, Kil Lyong Kim, Chong-Woo Bae, Kyung-Soo Hahm
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Clin Exp Pediatr. 1998;41(4):472-480. Published online April 15, 1998
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Purpose : In this study, natural pulmonary surfactant was extracted from bovine lung lavage and
its surface activity was determined. To investigate the usefulness of synthetic peptides reconstituted
with phospholipid as artificial surfactant, truncated peptides from surfactant protein (SP)-B
were synthesized and restored the surface tension lowering activities when appropriately
recombined with phospholipid.
Methods : Crude natural surfactant(CNS) was isolated from lung lavage by centrifugation... |
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- The Treatment of Croup with Nebulized Budesonide and Intramuscular Dexamethasone
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Jung Woo Lee, Young Ho Rah, Chong-Woo Bae, Sa Jun Chung, Yong Mook Choi
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Clin Exp Pediatr. 1998;41(3):331-337. Published online March 15, 1998
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Purpose : Steroids have anti-inflammatory effects which reduces inflammation and edema of the tissue. Thus, corticosteroids have been used for treatment of croup. The aim this study is to compare and assess the effects of intramuscularly injected dexamethasone and nebulized budesonide in treatment of moderate or severe croup.
Methods : Between July 1995 to June 1996, we have assessed 44 inpatients... |
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- Clinical Study and Diagnostic Value of the Lung Perfusion Scan
in Foreign Body Aspiration
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Gyo-Dang Koo, Young-Ho Rah, Chong-Woo Bae, Sa-Jun Chung, Yong-Mook Choi
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Clin Exp Pediatr. 1998;41(1):74-80. Published online January 15, 1998
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Purpose : Early diagnosis of foreign body aspiration and removal of the inhaled material may
save the patient from chronic illness and may prevent serious complications. At present the
diagnostic problems of bronchial foreign bodies are being solved by using the lung scanning
technique. Therefore, we investigated the clinical study and diagnositic value of the lung perfusion
scan in foreign body aspiration.
Methods : Eighteen... |
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- Surfactant Protein SP-A, B, and C: Purification and Biochemical Characterization
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Chong-Woo Bae, Yong-Mook Choi, Joo Hyun Kang, Kil Lyong Kim, Kyung Soo Hahn
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Clin Exp Pediatr. 1996;39(2):218-229. Published online February 15, 1996
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Purpose : Several kinds of exogenous pulmonary surfactants (SF), either synthetic or animalderived,
are being used for the replacement therapy in respiratory distress syndrome (RDS) of
newborn, especially in premature infants, and improved the neonatal mortality and morbidity.
Because synthetic preparations are lack of surfactant protein (SP) and animal-derived
preparations cause immunogenecity of heterogenous SP, there have been great necessity for the
development of next... |
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- Sequential Changes of Chest Radiographic Finding after Exogenous Surfactant Replacement Therapy in Neonates with RDS
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Hyeok Choi, Chong-Woo Bae, Sa-Jun Chung, Yong-Mook Choi
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Clin Exp Pediatr. 1995;38(2):151-158. Published online February 15, 1995
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Purpose : The chest radiograph is useful and reliable in assessing the severity and progres-sion of neonatal respiratory distress syndrome. To evaluate the effect of exogenous surfactant r eplacement therapy, we performed sequential observation of chest radiogratphic findings in ne-onates with respiratory distress syndrome.
Methods : Two groups of infant with RDS in mechanical ventilation therapy were studied. S-urfactant(S-Tx) group(n=36) was... |
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