- Original Article
- Re-Evaluation of Neonatal Screening Tests for Inborn Errors of
Metabolism with Dried Filter Paper Blood Spots
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Kye Shik Shim, Jin Soon Hwang, Jung Sub Lim, Se Young Kim, Choong Ho Shin, Sei Won Yang, Jung Hwan Choi, Chong Ku Yun, Jung-Han Song
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Clin Exp Pediatr. 1999;42(12):1639-1644. Published online December 15, 1999
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Purpose : There have been high rates of false positive and recall in neonatal screening test using the cut-off points set by the manufacturing company. So, it is necessary to re-evaluate the cut off values to minimize the false positive rates.
Methods : We collected capillary blood in dry filter paper from 996 healthy neonates on the third day in cases... |
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- Erratum
- Perinatal Factors Influencing Clinical Response to Surfactant Replacement Therapy in Neonates with Respiratory Distress Syndrome
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June Dong Park, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1998;41(8):1023-1032. Published online August 15, 1998
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Purpose : Surfactant replacement therapy significantly decreases neonatal complications and mortality in neonates with respiratory distress syndrome(RDS), but clinical responses to the treatment is not consistent. An analysis of the perinatal factors influencing the clinical response to the therapy is important for early detection of high risk and prognosis. The purpose of this study is to analyze the clinical... |
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- Association of Early Postnatal Neutropenia and Development of Bronchopulmonary Dysplasia in Preterm Infants
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Hee Seok Kim, Jun Dong Park, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1998;41(8):1033-1040. Published online August 15, 1998
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Purpose : To see if a similar relationship exists between the decreased number of circulating neutrophils and the development of bronchopulmonary dysplasia(BPD) in preterm infants, we tried to test the hypothesis that claims that preterm infants, who develop BPD, have decreased number of circulating neutrophils than those who do not develop BPD.
Methods : A retrospective cohort study was conducted in... |
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- Original Article
- Comparison of Continuous versus Intermittent Infusion of Indomethacin in PDA of Preterm Infants
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Yun Kyoung Lee, Hee Seok Kim, Kyoung Ran Park, Chan Hu Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1998;41(5):599-605. Published online May 15, 1998
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Purpose : Patent ductus arteriosus(PDA) of prematurity is very important disease to study because it causes many cases of perinatal morbidity and its incidence is now increasing. Nowadays indomethacin is the drug of choice for PDA closure, but its use has been limited due to its side effects. Therefore, we compared the effect and side effects of indomethacin according to... |
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- Comparison of Continuous Versus Intermittent Infusion of Indomethacin in PDA of Preterm Infants
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Yun Kyoung Lee, Hee Seok Kim, Kyoung Ran Park, Chan Hu Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1998;41(4):464-470. Published online April 15, 1998
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Purpose : Patent ductus arteriosus(PDA) of prematurity is very important disease to study because
it causes many cases of perinatal morbidity and its incidence is now increasing. Nowadays
indomethacin is the drug of choice for PDA closure, but its use has been limited due to its side
effects. Therefore, we compared the effect and side effects of indomethacin according to the infusion
method, continuous... |
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- The Efficacy of Fetal Ultrasonography and Postnatal Abdominal Ultrasonography for the Diagnosis of Neonatal Abdominal Mass
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Hee Eun Lee, Ee Kyung Kim, Hee Seok Kim, Yun Kyoung Lee, Chan Hwu Park, Kyung Ran Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Gui Won Park, Hwang Choi, Yong Choi, Chong Ku Yun
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Clin Exp Pediatr. 1998;41(3):299-306. Published online March 15, 1998
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Purpose : Most neonatal abdominal masses are benign in nature, but early detection and management is important to avoid the development of complications. So, we studied the causes of neonatal abdominal masses and the efficacy of ultrasonography for early detection and diagnosis.
Methods : We reviewed 36 newborn infants with abdominal masses who had been admitted to the nursery and Neonatal... |
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- Hemodynamic Effect of Nitric Oxide Inhalation in the Acute Hypoxic Pulmonary Hypertension Induced Newborn Piglet
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Yun Cil Chang, Won Soon Park, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1997;40(10):1394-1409. Published online October 15, 1997
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Purposes : Nitric oxide(NO) is classified as toxic gas in native states, but in most biologic
systems NO acts as a messenger molecule. NO is known as endothelium derived relaxing factor
that modulates tone of vascular smooth muscle. Inhaled NO has been reported to act as a selective
pulmonary vasodilator and we expect that NO inhalation can be used as a successful treatment
modality... |
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- Influence of Phototherapy on Incidence of Patent Ductus Arteriosus in Very Low Birth W eight Infants
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Hee Seok Kim, Ee Kyung Kim, Yun Kyoung Lee, Hee Eun Lee, Chan Hwu Park, Kyung Ran Park, Jun Dong Park, Beyong Il Kim, Woong Heum Kim, Jung-Hwan Choi, Yong Su Yun, Chong Ku Yun, Jeong Mi Lee
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Clin Exp Pediatr. 1997;40(10):1410-1418. Published online October 15, 1997
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Purpose : Patent ductus arteriosus(PDA) is a common disease in very low birth weight
infants(VLBWI). Hemodynamically significant PDA increases the morbidity and mortality of
premature infants. Based on experimental model, light inhibits the constriction of immature piglet' s
ductal rings. No specific mechanism adequately explains the effect of light on the relaxation of
PDA. Several hypotheses, including activation of photosensitive metabolites, alterations in receptors,
or... |
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- Genital Mycoplasmasin the Newborn Infants: Colonization, Prevalence and Clinical Significance
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Yun Sil Chang, Sung Gwon Kim, Beyong Il Kim, Won Soon Park, Bo Hyun Yoon, Eui Chong Kim, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1996;39(8):1084-1094. Published online August 15, 1996
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Purpose : The genital mycoplasmas: Ureaplasma urealyticum and Mycoplasma hominis have
recently assumed an increasing importance as neonatal pathogens especially in preterm infants.
The aim of the present study was to determine the prevalence of infections with these organisms
in newborn infants who were admitted in Neonatal Intensive Care Unit(NICU) and who were
suspected having infection in newborn nursery
Methods : Sixty four inborns who... |
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- Incidenceand Risk Factorsof the Retinopathy of Prematurity
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June Dong Park, Jung Hae Kweon, Woong Heum Kim, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun, Sang In Khwarg, Young Suk Yu
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Clin Exp Pediatr. 1996;39(3):326-337. Published online March 15, 1996
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Purpose : Retinopathy of prematurity(ROP) continues to be a serious problem in infants who survived with neonatal intensive care. Nevertheless, there is neither available data about the incidence of ROP which may be the basis of the epidemiology, nor analysis of the risk factors of ROP in Korea. The purpose of this retrospective study was to evaluate the incidence of... |
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- Morphologic Changes of Lung Parenchymal Tissue in Neonatal Rat Pups under Chronic Hyperoxia
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Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1994;37(8):1055-1064. Published online August 15, 1994
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We studied the effects of chronic hyperoxia (>95% oxygen for 14 days) in change of body weight, wet to dry ling weight ratio, and morphologic changes of lung tissue compared with that of room air (21% oxygen for 14 days) in Sprague-Dawley neonatal rat pups.
The results were as follows:
1) In neonatal rat pups exposed to room air (normoxia group), body... |
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- Incidence and Perinatal Risk Factors of Respiratory Distress Syndrome of Newborn
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Yun Sil Chang, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1994;37(8):1065-1077. Published online August 15, 1994
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Over a continuous 4-year period, from January 1989 till December 1992, 7,100 infants were born in Department of Obstetrics and admitted to Nursery or Neonatal Intensive Care Unit of Department of Pediatrics of Seoul National University Children's Hospital. Among them, 126 cases were diagnosed as respiratory distress syndrome (RDS) of newborn.
The total incidence of RDS among all the newborns(inborn)was 1.77%.... |
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- Meta-analysis of Impact of Neonatal Intensive Care on Neurodevelomental Outcome of Very Low Birth Weight Infants
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Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1994;37(7):937-945. Published online July 15, 1994
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We analyzed neurodevelopmental outcome data of 36 selected studies. Data of individual studies were pooled by birth weight group: <800g, <1,000g, <1,500g and by time period of birth year: Period I(pre-intensive care era), 1960-67:Period II(beginning period of intensive care), 1968-76:and Period III(established period of intensive care), 1977-87.
In all weight groups, survival and intact outcome rates based on live birth have... |
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- Periventricular-Intraventricular Hemorrhage in the Full-term Infant
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Hee Sup Kim, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun, In One Kim
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Clin Exp Pediatr. 1994;37(5):642-648. Published online May 15, 1994
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Intraventricular hemorrhage (IVH) is common in the premature infants and occurs mainly in subependymal germinal matrix. In contrast, IVH in the term infants is rare and different in pathogenesis and bleeding sites from those of the premature infants. Most studies of IVH in term infants have been studied by computerized tomography and postmortem examination. Brain ultrasonography which has become a... |
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- Risk Factors and Outcome of Bronchopulmonary Dysplasia
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Beyong Il Kim, Yun Sil Chang, Dong Woo Son, Hae Kyung Han, Jung-Hwan Choi, Chong Ku Yun, In One Kim, Kyung Mo Yeon, Je G. Chi
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Clin Exp Pediatr. 1994;37(1):78-88. Published online January 15, 1994
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The 45 neonates with bronchopulmonary dysplasia among 355 neonates who were managed with mechanical ventilation and oxygen therapy in NICU of Seoul National University Chhildren's Hospital from January 1, 1968 to December 31, 1991, were analyzed for risk factors and outcome.
The results were as follows:
1) The incidence of bronchopulmonary dysplasia was 12.7%
2) Respiratory Distress Syndrome was most common underlying problem.
3)... |
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- Outcome in Infants of Mothers with Systemic Lupus Erythematosus
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Chang Ryul Kim, Young Pyo Chang, Hee Seop Kim, Mi Jung Kim, Byung Il Kim, Jung-Hwan Choi, Chong Ku Yun, Bo Hyun Yoon, Hee Chul Syn, Syng Wook Kim, Seon Yang Park, Hahng Lee
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Clin Exp Pediatr. 1993;36(6):791-804. Published online June 15, 1993
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A large proportion of patients with systemic lupus erythematosus(SLE) are women of reproductive age. Their fetal outcome is undoubtedly less favourable than in haelthy women. Although there is no evidence of an increase in congenital anomalies, increased frequencies of miscarriage, stillbirth, growth retardation, and preterm delivery are recognized It mainly depends on the compromise of uteroplacental circulation such as renal... |
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- Case Report
- Transfusion-Acquired Cytomegalovirus Infections in Two Premature Infants
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Dong Wook Kim, Kyung Un No, Mi Jung Kim, Soon Mee Park, Hee Sup Kim, Young Pyo Chang, Hoan Jong Lee, Jung-Hwan Choi, Chong Ku Yun, Je Geun Chi
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Clin Exp Pediatr. 1992;35(8):1141-1147. Published online August 15, 1992
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Transfusion-acquired perinatal cytomegalovirus (CMV) infection can cause significant morbidity and mortality, particularly in premature infants with a birth wight of less than 1,500 gm. This recognizable syndrome consisted of deterioration of respiratory function, hepatosplenogaly, unusual gray pallor with disturbing septic appearance, lymphocytosis, thrombocytopenia and hemolytic anemia.
We experienced transfusion-acquired CMV infections in 2 premature infants with a birth weight of... |
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- Four Cases of Massive Infiltrating Congenital Cystic Hygroma Managed by Bleomycin Sclerosing Therapy
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Hyun Kwack, Dong Wook Kim, Kyung Woon No, Jun Heo, Sun Young Kim, Young Pyo Jang, Jung-Hwan Choi, Chong Ku Yun, Seong En Jung, Gui Won Park, Woo Gi Kim, In Won Kim, Kyung Mo Yeon
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Clin Exp Pediatr. 1992;35(8):1148-1156. Published online August 15, 1992
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Cystic hygroma is a true, benign, congenital multi-cystic tumor. It is thought to be arised from failure of the lymphatic system to communicate with the venous system. Frequently it occurs at birth, and it is found most commonly in the neck as painless and fluctuant mass.
For many years, surgical excision has been considered as the treatment of choice. However, excision... |
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- Original Article
- Cytomegalovirus Infection in Children: The Significance of CMV Specific IgM Antibody Test and Virus Isolation in the Urine
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Dong Wook Kim, Hyun Kwack, Seong Hee Jang, I Seok Kang, Hoan Jong Lee, Jung-Hwan Choi, Jeong Kee Seo, Chong Ku Yun
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Clin Exp Pediatr. 1992;35(7):890-901. Published online July 15, 1992
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The clinical pictures of 44 children with IgM antibody to CMV (cytomegalovirus) by ELISA(enzyme linked immunosorbent assay) were reviewed retrospectively, and the significance of serum CMV specific IgM antibody and virus isolation in the urine was analyzed.
Age of the patients with IgM antibody to CMV ranged from 23 days to 8 years 7 months, and median age was 2 months.... |
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- The Perceptions and Attitudes of Parents and Medical Personnel Toward Fever of Children
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Hyo Nam Cho, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1992;35(6):776-787. Published online June 15, 1992
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Children commonly complain of suffering fever ; however, as studies have demonstrated, parents of a febrile infant or young child are inclined to become overly concerned. The pupose of this study was to investigate the perceptions and attitudes of medical personnel as well as parents.
The parents of 189 children and 150 medical personnel (47 nurse-aides, 56 nurses, and 47 doctors)... |
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- A clinical study on neonatal bacterial meningitis.
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Yong Won Park, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1991;34(6):763-770. Published online June 30, 1991
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Clinical courses of 12 neonates who were confirmed as neonatal bacterial meningitis by CSF culture
or CSF latex agglutination test from January, 1986 to June, 1990, emphasizing on their complications
and treatments, were evaluated.
The results were summarized as follows;
1) The most common etiologic organism was E. coli (33.3%).
2) Two most common complications were ventriculitis (66.7%) and hydrocephalus (66.7%).
3) EVD with intraventricular antibiotics therapy was only... |
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- Clinical analysis on fetal and neonatal arrhythmia.
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Young Ah Lee, Chung Il Noh, Jung Hwan Choi, Jung Yun Choi, Yong Soo Yun, Chong Ku Yun
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Clin Exp Pediatr. 1991;34(4):507-514. Published online April 30, 1991
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저자들은 최근 5년 8개월 동안 서울대학교병원 소아과에서 경험한 태아 및 신생아기의 심부정맥 24
례에 대하여, 이들의 심전도, 심초음파도, 24시간 심전도 소견 및 임상 기록을 통하여，부정맥의 유
형과 여러 연관 요소에 대한 임상적 분석을 시행하였다. 발견된 부정맥은 심실조기수축 7례, 심방조
기수축 5례，상실성 빈맥 7례，동성서맥 2례, 심방조동 1례, 지속적인 1도 방실 블록 1례, 심실 빈맥
1례였다. 심장 이상은 10례（2 ASD : 4례, PDA : 1례，ASD+VSD :... |
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- A clinical observation on chylothorax in childhood.
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Mi Jin Jung, Joon Jai Kim, Young Ah Lee, Chung Il Noh, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1991;34(4):497-506. Published online April 30, 1991
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Fourteen patients who had developed a chylothorax in childhood during a ten year period, from
Jan. 1979 to July 1989, were reviewed by their hospital records. The chylothoraces occurred most
frequently as complications of cardiothoracic surgeries in eight patients(57%). Four cases followed
extrapericardial operations such as ligation of PDA and take-down of Blalock-Taussig shunt, and
four cases followed intrapericardial operations such as corrective operations... |
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- Acute pyogenic arthritis of hip in neonate and infant.
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Mi Jung Kim, Young Ah Lee, Young Pyo Chang, Hoan Jong Lee, Jung Hwan Choi, Chong Ku Yun, Hak Jin Min, In Ho Choi
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Clin Exp Pediatr. 1991;34(2):197-205. Published online February 28, 1991
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Acute pyogenic arthritis of hip is a serious infection that can lead to truly devastating complica-
tions especially in neonatal period and infancy. Clinical survey on twelve neonates and infants (14 hip
joints) with acute pyogenic arthritis of hip who were admitted to the Departments of Pediatrics and
Orthopedic Surgery, Seoul National University Hospital from Jan. 1980 to Dec. 1989 were done.
The results... |
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- Congenital cystic diseases of the lung.
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Won Soon Park, Young Pyo Chang, Hee Ju Kim, Young Yull Koh, Jung Hwan Choi, Chong Ku Yun, Joo Hyun Kim
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Clin Exp Pediatr. 1991;34(12):1671-1677. Published online December 31, 1991
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Congenital cystic diseases of the lung (CCDL) is a clinical group of disorders characterized by a
cystic appearance of pulmonary tissue. It can be classified into four distinct categories: 1) Congenital
lobar emphysema (CLE), 2) Congenital cystic adenomatoid malformation (CCAM), 3) Pulmonary
sequeestration (PS), and ^Bronchogenic cyst (BC).
24 patients with CCDL admitted to the Seoul National University Children’s Hospital from January
1984 to June... |
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- Mechanical ventilator care in the newborn infants.
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Young Pyo Chang, Yong Won Park, Won Soon Park, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1991;34(11):1526-1533. Published online November 30, 1991
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The widespread introduction of mechanically assisted ventilation into the neonatal intensive care
during the 1960s substantially improved the outcome of sick newborn infants, particularly those with
respiratory disorders. We studied the clinical features of 82 neonates, who were treated with
mechanically assisted ventilation in Neonatal Intensive Care Unit (NICU) at Seoul National Univer-
sity Children’s Hospital from January 1986 to August 1989 (the second... |
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- A case of pulmonary vascular air embolism in the newborn.
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Won Soon Park, Beom Soo Park, Hye Kyung Han, Jung Hwan Choi, Chong Ku Yun, Kyoung Mo Yeon, Je Geun Chi
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Clin Exp Pediatr. 1991;34(10):1422-1427. Published online October 31, 1991
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Pulmonary vascular air embolism is a rare, and almost invariably fatal complication of positive
pressure ventilation of newborn infants. There have only been 53 cases described in the world
literature to date.
We have experienced a case of pulmonary vascular air embolism in a premature newborn as a
complication of mechanical ventilation during the course of respiratory distress syndrome.
The pathophysiology and clinical characteristics of... |
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- Indomethacin therapy in premature infants with patent ductus arteriosus.
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Dug Ha Kim, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1991;34(10):1381-1390. Published online October 31, 1991
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Patent ductus arteriosus (PDA) is a common disease that occurred in 20 〜 40 percent of premature
infants. The incidence of PDA is inversely related to the gestational age and birth weight.
Hemodynamically significant PDA increases the morbidity and mortality of premature infants. So,
the management of PDA is one of the major problems in neonatal intensive care unit.
Based on experimental animal studies,... |
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- A Clinical Study of Childhood Non-Hodgkin's Lymphoma.
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In Sang Jeon, Hyo Seop Ahn, Chong Ku Yun
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Clin Exp Pediatr. 1990;33(6):807-820. Published online June 30, 1990
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To study the clinical characteristics and treatment result of childhood NHL, the retrospective study
was performed on 82 children with NHL, experienced at the department of Pediatrics, Seoul National
University Hospital, during 10 years from January 1979 to December 1988.
The results were as follows;
1) The sex ratio of male to female was 2.4:1.
2) The age of patients ranged from 8 months to 15 years,... |
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- Effect of Position Change on TcPO2 in the Newborns.
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Young Pyo Chang, Yong Joon Shin, Myoung Jae Choey, Beyong Il Kim, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1990;33(4):448-455. Published online April 30, 1990
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To determine the optimal position for the neonatal intensive care, transcutaneous oxygen tension
(TCPO2) was monitored in 20 healthy preterm infants and 20 healthy term infants using the
Radiometer Tc Oxgen Monitor in both supine and prone position. Also, transcutaneous oxygen
tension (TcPO2) was monitored with tilting change in each position.
When the infants were prone, TcPO2 rose by a mean of 7.36 mmHg... |
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- A Clinical Study of Periventricular-Intraventricular Hemorrhage in Very Low Birth Weight Infants.
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Myoung Jae Chey, Young Pyo Chang, Jung Hwan Choi, Yong Seung Hwang, Chong Ku Yun, In One Kim, Kyung Mo Yeon
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Clin Exp Pediatr. 1990;33(10):1341-1352. Published online October 31, 1990
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34 very low birth weight infants weighing 1,500 gms or less, who were admitted to the neonatal
intensive care unit of Seoul National University Children’s Hospital, were routinely studied with
serial real-time brain ultrasonography from August 1, 1986 to July 31, 1988.
Their medical records and the results of brain ultrasonography were analyzed to evaluate propor-
tion, severity, timing, clinical findings, outcome, associated periventricular... |
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- A Clinical Survey of Abdominal Masses in the Neonate.
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Beyong Il Kim, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1989;32(7):926-932. Published online July 31, 1989
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We reviewed 22 newborn patients with palpable abdominal mass among 9, 834 newborn infants
admitted to nursery and NICU of Seoul Natinal University Children’s Hospital from Jan. 1, 1983 to
Dec. 31, 1987.
The results were summarized as follows:
1) The incidence was 2.2/1,000 admission. The difference of incidence was not significant between
preterm infants and term infants.
2) The most common etiology of neonatal abdominal masses is... |
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- Clinical Application of Shake test od Gastric Aspiretes for the Prediction od Respiratory Distress Syndrome in the Newborn infants.
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In Sang Jeon, Hann Tchah, Myoung Jae Choi, Beyng Il Kim, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1989;32(3):349-358. Published online March 31, 1989
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To study the predictive value of gastric aspirates shake test on respiratory distress syndrome (RDS)
in the newborn infants, we carried out the shake test on gastric aspirates of all newborn who admitted
to NICU of Seoul National University Hospital from July 1986 to December 1987. We successfully
carried out gastric aspirates shake test on 96 newborn infants and analyzed the relation between
gastric... |
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- Study on the Temperature Measurement in the Newborn Infants.
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Eun Saing Jee, Young Pyo Chang, Jung Hwan Choi, Chong Ku Yun, Yong Ran Kim, Myoung Sook Lee
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Clin Exp Pediatr. 1989;32(12):1632-1636. Published online December 31, 1989
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We measured body temperatures and stabilization times of 100 term and 52 preterm infants at four
sites. The sites were core, aural, rectal and axilla in order of degree of temperature.
There was significant difference between term and preterm infants (term infant higher, p<0.001).
Mean difference between axillary and rectal temperatures was 0.501C(rectal higher). Mean difference
between rectal and core temperatures was 0.10lC(core higher).... |
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- Normal TSH Levels in Neonates by TSH Screening test.
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Jae Won Song, Jong Lin Rhi, Sei Won Yang, Jung Hwan Choi, Chong Ku Yun, Hyung Ro Moon, Bo Youn Cho, Chang Soon Koh
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Clin Exp Pediatr. 1988;31(6):754-761. Published online June 30, 1988
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In 110 term neonates without perinatal problems who were bom in SNUH, blood TSH levels were
measured by TSH screening test for congenital hypothyroidism. The results are as follows
1) Normal TSH level was 14.8±7.8 µU/ml, 8.8±4.7 µU/ml, and 6.5±2.7 µU/ml in neonates of age
0 〜24 hours, 24—48 hours, and 48〜72 hours respectively, and all TSH values in neonates of age
48〜72 hours were... |
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- A Clinical Observation on Esolhageal Atresia and Tracheoesophageal Fistula.
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In Sang Jeon, Jung Hwan Choi, Jeong Kee Seo, Chong Ku Yun, Sung Chul Lee, Kwi Won Park, Woo ki Lee
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Clin Exp Pediatr. 1988;31(6):691-699. Published online June 30, 1988
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To study the clinical characteristics of esophageal atresia and tracheoesophageal fistula, we
carried out a retrospective review on medical records of 39 patients who were diagnosed as that by
the operation, autopsy or radiolgy at the department of Pediatrics and Pediatric Surgery, Seoul
National University Hospital between January 1980 and June 1987.
The results were summarized as follows;
1) Type A was most common (94.8%) among... |
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- Pulmonary Air Leaks in the Newborn.
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Myung Chul Cho, Beyong Il Kim, Son Moon Shin, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1987;30(7):727-734. Published online July 31, 1987
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A clinical study was performed on 17 cases of pulmonary air leaks in the newborn who were
admitted to the NICU of SNUH from Jan. 1980 to Jun. 1986.
The results were as follows:
1) Spontaneous air leaks were 2 cases (11.8%) and secondary air leaks were 15 cases (88.2%).
2) Of the 17 cases of pulmonary air leaks, 9 cases (53.0%) were premature infants, 10... |
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- Clinical Observations on Neonatal Sepsis.
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Beyong Il Kim, Hae Lim Chung, Yoon Deok Kim, Weon Soon Park, Son Moon Shin, Hoan Jong Lee, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1987;30(2):130-138. Published online February 28, 1987
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We studied the 73 cases of proven neonatal sepsis among 11,102 newborn infant under 1 month of
age, admitted to the pediatric ward, the nursery and the NICU of Seoul National University Hospital
from Jan. 1, 1980, to Dec. 31, 1985.
The results were as follows:
1) The incidence was 6.6/1000 live births. Incidence of male babies was 8.3/1000 live births. The
morbidity rate of... |
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- A Case of Potter Syndrome with Bilateral Polycystic Kidneys.
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Chun Hwa Lee, Jung Hwan Choi, Yong Choi, Chong Ku Yun, Yeon Lim Suh, Je G Chi, Son Moon Shin
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Clin Exp Pediatr. 1987;30(11):1282-1286. Published online November 30, 1987
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In 1946, Potter described a series of 20 cases of infants in whom bilateral absence of the kidneys was
associated with hypoplasia of the lungs and characteristic faces.
Afterwards it has been known that any condition that causes significant reduction in urine formation or excretion will result in oligohydramnios accounts for many of the nonrenal features of Potter
syndorme. We report a case... |
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- Blood Pressure Change in the Neonates during Abdominal Examination.
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Young Sun Kim, Yoon Deok Kim, Jung Hwan Choi, Chong Ku Yun, Son Moon Shin
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Clin Exp Pediatr. 1987;30(11):1201-1206. Published online November 30, 1987
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During abdominal palpation in the 50 full term neonates, blood pressure changes were measured by
automatic oscillometric blood pressure monitor. The systolic blood pressure value at resting stage
was 61.2 ±2.9 mmHg, and during the liver, the left kidney and the bladder palpation, it was signifi-
cantly elevated to 67.2±4.7 mmHg, 68.1 ±4.8 mmHg, 69.0±4.6 mmHg respectively (P< 0.005). The
diastoloic pressure value at... |
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- Risk Factors for Retinopathy of Prematurity (Retrolental Fibroplasia)
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Beyong Il Kim, Jung Hwan Choi, Chong Ku Yun, Jae Heung Lee, Son Moon Shin
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Clin Exp Pediatr. 1987;30(10):1092-1099. Published online October 31, 1987
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We studied 51 premature babies who were admitted to the N.I.C.U. of S.N.U.H., managed with
oxygen with or without artificial ventilation due to respiratory distress, and examined by indirect
ophthalmoscopy between April 1, 1982 and March 31, 1986.
The results were as follows;
1. Among 51 premature babies, retinopathy of prematurity developed in 12 cases (24%).
2. The high distribution of retinopathy of prematurity was observed in... |
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- A Study of Blood Pressure Measurement in Newborn Infants.
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Yoon Deok Kim, Joong Whan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1986;29(8):819-829. Published online August 31, 1986
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The inability to detect Korotkoff sounds in infants have in the past made it difficult for most pediatricians to measure blood pressures by indirect conventional sphygmomanometry. Now, however, Korotkoff sounds,
or the mechanical events which produce them, can be sensed with an ultrasonic Doppler device.
The author measured systolic and diastolic blood pressure using a Doppler arteriokinetog raphic instrument during 6... |
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- Case Report
- Two Cases of Hemolytic Disease of Newborn due to Anti-E.
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Se Won Park, Young Sun Kim, Jung Hwan Choi, Hyo Seop Ahn, Chong Ku Yun
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Clin Exp Pediatr. 1986;29(2):203-208. Published online February 28, 1986
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Isoimmune hemolytic disease of the newborn is a disease which is caused by maternal sensitization to
one of the fetal blood factors.
This report presented two esses of isoimmune hemolytic disease due to anti-E in 2 male newborns who were admitted to Seoul University Hospital because of jaundice. Antibody screening and antibody identification tests were made which revealed anti-E antibody... |
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- Original Article
- Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children.
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Chong Ku Yun, Hae Il Cheong, Chung Il Noh, Jung Yun Choi, Yong Choi, Kwang Wook Ko, Kyung Mo Yeon
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Clin Exp Pediatr. 1985;28(6):555-563. Published online June 30, 1985
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PRA in peripheral vein, both renal veins and both inferior vena cava (JVC) both proximal and distal to the drainage of the both renal veins was measured in 80 normotensive children with no renal disease undergoing routine cardiac catheterization due to congenital heart disease which did not cause significant hemodynamic changes in most of them. And we presented the results... |
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- clinical Observation on Neonatal Necrotizing Enterocolitis(Nec).
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Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1985;28(5):423-434. Published online May 31, 1985
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A clinnical observation was done on 9 cases of NEC who were admitted to the NICU and Pediatric and Pediatric Surgery Ward, Seoul National University Hospital during the period of 5 years from January 1979 to December, 1984. The results were as follows: 1)Among 9 cases of NEC, LBWI below 2,500 g were 3 cases(33.3%) and premature babies below 38... |
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- Associated Ventilation with Mechanical Aids in Newborn Infants.
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Eue Cho Yang, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1985;28(5):435-447. Published online May 31, 1985
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Clinical features of 85 neonates who treated with assisted ventilation in Neonatal Intensive Care Unit at Seoul National University Hospital from April ’80 to Dec. 5 84 were analyzed with special respect to mechanical aids.
The results were as follows; 1)According to diagnostic categories, 56 cases (66%) were hyaline membrane disease (HMD), 14 cases (16%) were postasphyxia syndrome (PAS), 9 cases... |
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- Clinical Studies on Congenital Malformation.
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Jung Hwan Choi, Hun Jong Chung, Chong Ku Yun
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Clin Exp Pediatr. 1985;28(4):378-385. Published online April 30, 1985
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Although pediatrics has been advanced progressively in the past years, congenital malformations are known as a major cause of neonatal death. In spite of every efforts of pediatricians and obstetricians to exclude the possible factors of congenital malformations by antenatal care, the general incidence of congenital malformations has not been decreased yet. So, we surveyed the incidence of congenital malformations... |
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- A Clinical Study on Neonatal seizures.
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Chong Young Park, Myung Kul Yun, Jung Hwan Choi, Yong Seung Hwang, Chong Ku Yun
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Clin Exp Pediatr. 1985;28(3):225-235. Published online March 31, 1985
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Clinical Observations were made on 96 cases of neonatal seizure who were admitted to the Department of Pediatrics, Seoul National University Hospital during the period of 5 years from June, 1979 to May, 1984.
The results were as follows: 1)The most frequent cause of neonatal seizure was sepsis with or without meningitis
(27.4%), and followed by hypocalcemia(23.4%)> hypoxic-ischemic brain damage(12.9%), hypoglycemia(8.0%), intracranial... |
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- Correlation between the Gestational Age and Development of Renal Function in Preterm Infants.
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Kyu Gap Hwang, Chong Ku Yun
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Clin Exp Pediatr. 1984;27(4):326-334. Published online April 30, 1984
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In neonatal period, there is a rapid increament of renal function. About this issue, there were many studies in fullterm infants. But it is rare in preterm infnats in Korea. From April to September in 1983, prosepctive study was done for the evaluation of correlationship between the gestational age and development of renal function in 14 preterm infants. The results... |
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- Premature Rupture of Membranes and Its Effect on Neonatal Sepsis.
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Weon Soon Park, Chong Ku Yun
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Clin Exp Pediatr. 1984;27(12):1162-1167. Published online December 31, 1984
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A clinical study was carried out to evaluate the effect of PROM on neonatal sepsis on
626 newborns with PROM, who had been born at SNUH during the two-year period from January 1982 to December 1983. The results were as follows;
1) The incidence of PROM was 16.5% and the frequency of prematurity and neonatal sepsis was increased in newborns with PROM. 2) The... |
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- Clinical Observation of Neonatal Skin.
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Kyu Han Kim, Hee Chul Eun, Chong Ku Yun
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Clin Exp Pediatr. 1984;27(11):1063-1069. Published online November 30, 1984
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A clinical study of neonatal skin was carried out from March 1983 to November 1983. This
study sought to investigate the incidence and clinical features of neonatal skin abnormalities.
729 neonates of Seoul National University Hospital were included in this study and the
results can be summarized as follows;
1) Mongolian spots were observed in 80.2%, occuring most frequently in the sacral area.
2) Salmon patches... |
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- Clinical Assessment of Extrahepatic Biliary Atresia and Neonatal Hepatitis.
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Chong Ku Yun, Eue Cho Yang
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Clin Exp Pediatr. 1984;27(1):33-42. Published online January 31, 1984
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A clinical assessment was carried out in 37 cases with Extrahepatic biliary atresia (EHBA) and 35 cases with Neonatal hepatitis (NH), who were admitted to the Dept, of Pediatrics and Pediatric Surgery, Seoul National University Hospital, during the 30 months from January 1980 to June 1982. The following results were obtained;
1)By sex distribution, 40% of EHBA and 69% of NH... |
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- Simplification of Ballard'S Scoring System in Clinical Estimation of Gestational Age in Newborn Infants.
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Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun, Yong Ik Kim
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Clin Exp Pediatr. 1983;26(3):228-236. Published online March 31, 1983
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Clinically, it is often required to identify that neonates are small, appropriate, or large-for-
gestational age, since the clinical course, outcome, and problems are quite different in each
group of infants. For this, accurate estimation of gestational age is required in addition to
birth weight.
Several methods to assess the gestational age based on the physical and neurological char-
acteristics of neonates have been developed... |
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- Phototherapy for Neonatal Hyperbilirubinemia.
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Il Suck Chang, Chong Ku Yun
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Clin Exp Pediatr. 1983;26(1):8-13. Published online January 31, 1983
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Daylight phototherapy group (27 newborn infant) were compared with blue light photother-
apy group (43 newborn infant) in serum total bilirubin decrements with phototherapy.;
study A. For the purpose of dose-response relationship, 4 group (total 60 newborn infant) were compared the effectiveness of phototherapy based on radiant reflux (study B); Group 1, 5.46±0.65 ㎼/cm2.nm(mean±SD) Group 2,4.48±0.70 ㎼/cm2. nm (mean±SD)... |
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- Case Report
- Disseminated Intravascular Coagulation in an Infant Born after Abruptio Placentae.
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Soon Ung Kang, Jung Hwan Choi, E Boong Kwon, Chong Ku Yun, Kwang Wook Ko, Je G Chi, Chul Woo Kim
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Clin Exp Pediatr. 1982;25(7):730-736. Published online July 31, 1982
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Premature separation of the placenta(abruptio placentae), as a serious obstetric complication, has been recognized to be associated with disseminated intravascular coagulation(DIC) in the newborn period. However, pathologic evidence for DIC generally has been lacking or rarely reported. Recently we have experienced one case of DIC in an infant born after abruptio placentae. The infant had suffered from cyanosis, dyspnea and... |
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- Hyaline Membrane Disease (Five cases report including two autopsy cases).
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Jun Hee Kang, Young Min Ahn, Joong Gon Kim, Chun Haeng Park, Jeong Kee Seo, Ok Ja Hwang, Chong Ku Yun, Yoon Seong Lee, Shin Eun Choi, Je G Chi
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Clin Exp Pediatr. 1981;24(9):882-890. Published online September 15, 1981
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The hyaline membrane disease is not a common disease in Korea. Only a few reports of small scale are avaiable in the literature. We have experienced 5 cases of HMD during approximately 1 year period. The diagnosis was made either on characteristic clinical and roentgenological features or postmortem examination. The birth weights of these cases were in the range of... |
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- A Case of Moyamoya Disease in Child.
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Joong Gon Kim, Sang Il Lee, Baek Youn Choo, Kwang Chan Do, Chong Ku Yun
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Clin Exp Pediatr. 1981;24(8):786-790. Published online August 15, 1981
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A childhood case of moyamoya disease with subarachnoid hemorrhage is reported. This patient exhibited left hemiparesis, dysarthria, convulsion and mental retardation. He also had characteristic angiographic picture: occlusion of supraclinoid segment of both internal carotid arteries, combined with collateral networks in the base of brain. |
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- Original Article
- Total Serum bilirubin concentration of Physiologic Jaundice of Healthy, full-term Infants.
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Eung Sang Choi, Chang Hyo Lee, Chong Ku Yun
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Clin Exp Pediatr. 1980;23(2):111-117. Published online February 15, 1980
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The bilirubin formed in utero by the fetus can cross the placena and be excreted by the maternal liver. After birth, however, the infant must excrete its own bilirubin and hepatic clearance is not sufficient to prevent its accumulation during first week of life This transition has been physiologic jaundice and defined as an elevation of serum bilirubin that does... |
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- Feeding Result of Maeil Drymilk G in Normal Full Term Newborn.
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Dong Whan Yi, Chong Ku Yun, Kuang Wook Ko
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Clin Exp Pediatr. 1978;21(4):284-289. Published online April 30, 1978
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20 normal full term newborns have been fed with 15% concentration of Maeil Drymilk G for 7 days at the department of Pediatrics, Seoul National University Hospital. Feeding results was obtained as follows. 1. General condition was good. They lost approximately 2% of their birth weight during the 1st day and were beginning to regain birth weight on the 4th... |
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- Clinical Observation on Prematurity and Low-Birth-Weigth.
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Kyoo Dug Lee, Ho Sung Lee, Chong Ku Yun
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Clin Exp Pediatr. 1978;21(3):176-182. Published online March 31, 1978
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Clinical observation was performed on 1412 cases of neonates which was seen at S.N.U.H. during the past 2years from Jan. 1975 to Dec. 1976. The results ware as following: 1. The incidence of prematurity (below 38wks) was 12.1% and the incidence of S.B.W. was 9.8% 2. The mortality rate of prematurity and L.B.W. was 7.35%. 3. The average sex ration... |
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- The Examination of Muscle Tonus in Newborn Infants
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Chong Ku Yun, Chang Hyo Lee
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Clin Exp Pediatr. 1975;18(4):289-293. Published online April 30, 1975
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Neurological examinations were done in 143 normal full-term newborn infants, born at Seoul National Univ. Hospital, according to their type of delivery. The authors have observed the posture and the passive muscle tone of the infants including heel to ear manoeuvre, popliteal angle, dorsiflexion angle of foot, and scarf sign for one week of postnatal period, and compared the data... |
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- A Study on Perception in Newborn Infants
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Chong Ku Yun, Chang Hyo Lee
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Clin Exp Pediatr. 1975;18(12):909-911. Published online December 31, 1975
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We examined the responses about mother’s voice, flickering red light from an electric bulb and an optokinetic tape, in 7 days and 28 days old newborn infant respectively, and observed specific responses about mother’s voice and flickering red light. These facts suggest that newborn infants have somewhat higher level of the central nerve
:function. We expect to apply this to further... |
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- Neurological Examination in the Neonate of Prone Versus Supine Placement
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Chong Ku Yun, Hark Jin Chang
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Clin Exp Pediatr. 1974;17(1):63-66. Published online January 31, 1974
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161 Normal full-term newborn infants born at Seoul National Univ. Hospital were divided into
two groups, supine and prone. The authors have observed the posture and the passive muscle
tone of the infants including heel to ear manoeuvre, popliteal angle, dorsiflexion angle of foot and
scarf sign for one week of postnatal period, and compared the data between two groups.
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- Experimental Studies of Acute Liver Damage in Young White Rats
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Chong Ku Yun
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Clin Exp Pediatr. 1973;16(7):543-564. Published online July 31, 1973
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This study was attempted to analysis whether there are any differences or not in the susceptibility to acute liver damage due to chemical hepato-toxic agents between young white rat and mature one. The experiment was carried out in four divided groups as follows; control group, CC14 group, chloroform group, and ethionine group. Each group was subdivided again into weight of... |
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