- Original Article
- Gastroenterology
- Endoscopic postdilatation application of Mitomycin C in children with resistant esophageal strictures
- Yasser K. Rashed, Mohamed El-Guindi
- Clin Exp Pediatr. 2019;62(10):395-399. Published online June 24, 2019
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Background: The esophagus is the most common part of gastrointestinal (GI) tract at the risk of stricture. Benign disorders are the leading causes of narrowing. Caustic ingestion is the most common cause of esophageal stricture in children, especially in developing countries. Clinical responses to the topical application of Mitomycin C in various medical procedures have been reported.
Purpose: The study aimed...
- Editorial
- Gastroenterology
- Can proton pump inhibitors cause intestinal inflammation in children?
- Ben Kang
- Clin Exp Pediatr. 2019;62(10):384-385. Published online October 2, 2019
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- Review Article
- Gastroenterology
- The role of fecal calprotectin in pediatric disease
- Su Jin Jeong
- Clin Exp Pediatr. 2019;62(8):287-291. Published online March 28, 2019
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Fecal calprotectin (FC) is a calcium- and zinc-binding protein of the S100 family, mainly expressed by neutrophils and released during inflammation. FC became an increasingly useful tool both for gastroenterologists and for general practitioners for distinguishing inflammatory bowel disease (IBD) from irritable bowel syndrome. Increasing evidences support the use of this biomarker for diagnosis, follow-up and evaluation of response to...
- Original Article
- Gastroenterology
- The role of Lactobacillus reuteri DSM 17938 for the absorption of iron preparations in children with iron deficiency anemia
- Jeanette Manoppo, Hilda Tasiringan, Audrey Wahani, Adrian Umboh, Max Mantik
- Clin Exp Pediatr. 2019;62(5):173-178. Published online January 25, 2019
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Purpose: To determine whether Lactobacillus reuteri DSM 17938 plays a role in absorption of iron preparations given to children with iron deficiency anemia (IDA). Methods: We performed a quasi-experimental study involving pre- and postintervention tests using a control group in North Sulawesi province, Indonesia, between July and September 2017. We conducted a single-blind controlled trial that included primary school children who...
- Nonalcoholic fatty liver disease in obese and nonobese pediatric patients
- Eun Jeong Kim, Hyun Jin Kim
- Clin Exp Pediatr. 2019;62(1):30-35. Published online September 17, 2018
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Purpose: Obesity is risk factor for nonalcoholic fatty liver disease (NAFLD). However, nonobese patients are also increasingly susceptible to NAFLD. The aim of this study was to compare the clinical characteristics of obese and nonobese pediatric patients with NAFLD. Methods: We retrospectively studied 68 patients who were diagnosed with NAFLD between January 2010 and October 2016 at 10–18 years of age....
- Review Article
- Gastroenterology
- Esophageal perforation in children: etiology and management, with special reference to endoscopic esophageal perforation
- Krishna Kumar Govindarajan
- Clin Exp Pediatr. 2018;61(6):175-179. Published online June 25, 2018
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Perforation of the esophagus is an uncommon problem with significant morbidity and mortality. In children undergoing endoscopy, the risk of perforation is higher when interventional endoscopy is performed. The clinical features depend upon the site of esophageal perforation. Opinions vary regarding the optimal treatment protocol, and the role of conservative management in this context is not well established. Esophageal perforation...
- Case Report
- Gastroenterology
- Intestinal duplication revealed by posterior reversible encephalopathy syndrome
- Yosra Kerkeni, Hela Louati, Mourad Hamzaoui
- Clin Exp Pediatr. 2018;61(4):132-134. Published online April 23, 2018
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We report a unique case of intestinal duplication detected on posterior reversible encephalopathy syndrome (PRES) in a 13-year-old girl. She was admitted to the pediatric Emergency Department because of generalized seizures. Radiological assessment revealed a large, well-defined, thick-walled cystic lesion in the mid abdomen, suggestive of duplication cyst associated to a PRES. Exploration confirmed the diagnosis of ileal duplication cyst,...
- Original Article
- Gastroenterology
- Clinical manifestation of
Campylobacter enteritis in children - Joon Yeol Bae, Dong Hyuk Lee, Kyung Ok Ko, Jae Woo Lim, Eun Jeong Cheon, Young Hwa Song, Jung Min Yoon
- Clin Exp Pediatr. 2018;61(3):84-89. Published online February 28, 2018
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Purpose Timely antibiotic therapy in selected cases of diarrhea associated with bacterial infections can reduce the duration and severity of illness and prevent complications. The availability of a predictive index before identification of causative bacteria would aid in the choice of a therapeutic agent.
Methods The study included patients admitted to the pediatrics unit at Konyang University Hospital for acute inflammatory diarrhea from...
- Characteristics and prognosis of hepatic cytomegalovirus infection in children: 10 years of experience at a university hospital in Korea
- Chae-Yeon Min, Joo Young Song, Su Jin Jeong
- Clin Exp Pediatr. 2017;60(8):261-265. Published online August 14, 2017
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Purpose Studies on cytomegalovirus (CMV) infections in immunocompetent children are lacking, and minimal information is available in the medical literature on hepatic manifestations and complications of CMV. The aims of this study were to evaluate the clinical characteristics, laboratory data, and prognosis of children with CMV hepatitis, and to investigate its prevalence at a single medical center in Korea over a...
- Case Report
- Gastroenterology
- Acute gastritis associated with Epstein-Barr virus infection in a child
- Ji Mok Kim, Chun Woo Song, Kyu Sang Song, Jae Young Kim
- Clin Exp Pediatr. 2016;59(Suppl 1):S68-S71. Published online November 30, 2016
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Infectious mononucleosis is Epstein-Barr virus (EBV) inducing a self-limiting clinical syndrome characterized by fever, sore throat, hepatosplenomegaly, and generalized lymphadenopathy. Gastrointestinal symptoms of EBV infection are nonspecific and occur rarely. EBV inducing acute gastrointestinal pathology is poorly recognized without suspicion. Careful consideration is needed to diagnose gastric involvement of EBV infection including gastric lymphoma, gastric cancer, and gastritis. A few...
- Granular cell tumor of the esophagus in an adolescent
- Ji Sun Lee, Kyung Ok Ko, Jae Woo Lim, Eun Jeong Cheon, Young Jin Kim, Jang Sin Son, Jung Min Yoon
- Clin Exp Pediatr. 2016;59(Suppl 1):S88-S91. Published online November 30, 2016
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Esophageal granular cell tumor (GCT) is a rare neoplasm originating from the Schwann cells of the submucosal neuronal plexus. Histology is the gold standard for its diagnosis. Endoscopic resection or surgical excision should be considered, depending on the potential for malignancy. Here, we report a case of an esophageal GCT in an adolescent. A 12-year-old boy presented with a 1-year...
- Original Article
- Gastroenterology
- Risk factors of delayed diagnosis of acute appendicitis in children: for early detection of acute appendicitis
- Jea Yeon Choi, Eell Ryoo, Jeong Hyun Jo, Tchah Hann, Seong Min Kim
- Clin Exp Pediatr. 2016;59(9):368-373. Published online September 21, 2016
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Purpose This study examined the risk factors of a delayed diagnosis of acute appendicitis in children undergoing an appendectomy.
Methods This retrospective study involved children aged below 18 years, who underwent an appendectomy. After dividing them into a delayed diagnosis group and nondelayed diagnosis group according to the time interval between the initial hospital visit and final diagnosis, the risk factors of delayed...
- Clinical significance of serum alanine aminotransferase and lifestyle intervention in children with nonalcoholic fatty liver disease
- Kyoung Ah Kwon, Peter Chun, Jae Hong Park
- Clin Exp Pediatr. 2016;59(9):362-367. Published online September 21, 2016
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Purpose This study aimed to investigate the clinical significance of serum alanine aminotransferase (ALT) levels in children with nonalcoholic fatty liver disease (NAFLD) and the effect of lifestyle intervention on NAFLD.
Methods The clinical data of 86 children diagnosed with NAFLD were reviewed retrospectively. Forty-six patients belonged to the elevated ALT group and 40 to the normal ALT group. The clinical parameters of...
- Dietary habits and gastroesophageal reflux disease in preschool children
- You Jin Choi, Eun Kyo Ha, Su Jin Jeong
- Clin Exp Pediatr. 2016;59(7):303-307. Published online July 31, 2016
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Purpose To identify the relationship between dietary habits and childhood gastroesophageal reflux disease (GERD) in preschool children.
Methods We performed a questionnaire study to analyze the relationship between dietary habits and GERD in 85 preschool children with GERD and 117 healthy children of the same age.
Results Irregular and picky eating were more p–revalent in the GERD group than in the control group (odds ratio...
- Review Article
- Gastroenterology
- Nutritional concerns in pediatric inflammatory bowel disease
- Yong Joo Kim
- Clin Exp Pediatr. 2016;59(6):247-251. Published online June 30, 2016
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The pathophysiology and fundamental etiologic mechanism of inflammatory bowel disease (IBD) is not well understood even though therapeutic regimens and drugs are rapidly evolutionary. IBD has complicated connections with genetic, immunologic, gut microbial, environmental, and nutritional factors. It is not clearly well known to the physicians how to feed, what nutrients are more helpful, and what food to be avoided....
- Case Report
- Gastroenterology
- A giant choledochal cyst in infancy: a case report
- Nursel Yurttutan, Suleyman Cuneyt Karakus, Naim Koku, Mustafa Demirci, Ramazan Ucak
- Clin Exp Pediatr. 2016;59(5):239-241. Published online May 31, 2016
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Choledochal cyst is a dilation that encloses the intrahepatic or both extra- and intrahepatic portions of the biliary ducts. Postnatally, ultrasonography is the initial diagnostic modality of choice, allowing for precise measurements of intra- or extrahepatic duct dilatation and identification of stones and sludge. Symptoms depend on the age at presentation. Common bile duct malformations should be considered as a...
- Original Article
- Gastroenterology
- Efficacy of proton pump inhibitors and H2 blocker in the treatment of symptomatic gastroesophageal reflux disease in infants
- Hamid Reza Azizollahi, Mandana Rafeey
- Clin Exp Pediatr. 2016;59(5):226-230. Published online May 31, 2016
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Purpose Gastroesophageal reflux disease (GERD) occurs in pediatric patients when reflux of gastric contents presents with troublesome symptoms. The present study compared the effects of omeprazole and ranitidine for the treatment of symptomatic GERD in infants of 2-12 months.
Methods This study was a clinical randomized double-blind trial and parallel-group comparison of omeprazole and ranitidine performed at Children Training Hospital in Tabriz, Iran....
- Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis
- Dong Ho Shim, Dong Yeon Kim, Ky Young Cho
- Clin Exp Pediatr. 2016;59(3):126-131. Published online March 31, 2016
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Purpose To evaluate the diagnostic value of the Vesikari Scoring System (VSS) as an early predictor of pathogens in children with acute gastroenteritis (AG).
Methods In this retrospective study, the VSS score, absolute neutrophil count (ANC), and C-reactive protein (CRP) levels were analyzed in 107 hospitalized children with AG, aged 6 months to 17 years. Patients were divided into nonspecific, viral, and bacterial...
- Recent viral pathogen in acute gastroenteritis: a retrospective study at a tertiary hospital for 1 year
- Hye Il Jin, Yoo Mi Lee, You Jin Choi, Su Jin Jeong
- Clin Exp Pediatr. 2016;59(3):120-125. Published online March 31, 2016
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Purpose Viral gastroenteritis among children is mainly caused by rotavirus, norovirus, astrovirus, or adenovirus strains. However, changing socioeconomic conditions and a rotavirus vaccination program may be affecting the prevalence of these viral infections. Therefore, we aimed to elucidate the season-specific trends in viral infections for facilitating prophylaxis and surveillance in our region.
Methods We evaluated 345 pediatric patients (203 males, 142 females; age,...
