Question: Is there a reliable model to predict intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD)? Finding: We constructed 5 machine learning models to predict IVIG-resistant KD. Extreme gradient boosting (XGBoost) model was superior to logistic, support vector machine, light gradient boosting machine and multiple layers perception models. The SHAP (SHapley Additive exPlanations) value interpreted the contribution of each feature in XGBoost model. Meaning: XGBoost model showed the excellent performance to predict IVIG-resistant KD with explainable and visualizable machine learning algorithm. |
· Children with attention deficit hyperactivity disorder (ADHD) tend to have impaired motor performance that may affect their growth and development. · Although widely used among children with developmental disorders, the Bruininks-Oseretsky Test of Motor Proficiency (BOTMP) is used sparsely among children with ADHD. · Assessment by the BOTMP increases our understanding of the motor repertoire of children with ADHD. · Wider usage of the BOTMP will enable more comprehensive planning of rehabilitation goals to enhance the motor abilities of children with ADHD. |
∙ The application of 3-dimensional (3D) printing in orthopedic oncology is summarized into bone and tumor modeling, patient-specific instruments (PSIs), custom-made implants, and tissue engineering. ∙ The 3D-printed customized implant is the most central application, while modeling and PSI often play adjunct roles. ∙ Short-term surgical outcomes of custom-made 3D-printed implants are promising. |
Voiding cystourethrography (VCUG) is a commonly performed diagnostic procedure for the evaluation of vesicoureteral reflux with urinary tract infection or congenital renal diseases in children. The procedure is relatively simple and cost-effective, and complications are very rare. The iatrogenic complication of VCUG range from discomfort, urinary tract infection to bacteremia, as well as bladder rupture. Bladder rupture is a rare... |
The genitourinary tract and gastrointestinal system are interdependent but share the same embryological origin, pelvic region, and sacral innervation. Although children with voiding disturbances often present with bowel dysfunction, this coexistence was considered coincidental until recently. However, it is now accepted that dysfunction in emptying of both systems is interrelated. Afferent impulses carrying sensory information are transmitted through the spinal... |
Purpose : This study was performed to determine the developmental expression pattern of nerve growth factor(NGF) in the urine of healthy children. It was hypothesized that NGF may contribute to the development of the spinobulbospinal micturition reflex that represents the adult micturition pattern. Methods : Voided urine was collected in 60 healthy children during the first 5 years of life(0-1 month,... |
Purpose : To evaluate the predictable factors for why initial intravenous immune globulin(IVIG) therapy failed and the outcome of coronary lesions after additional IVIG retreated in initial IVIG- resistant Kawasaki disease(KD). Methods : Retrospective studies were performed on 284 cases of KD treated with one episode of high-dose IVIG and 63 cases with additional IVIG retreatment at this hospital from January... |
Purpose : Suprapubic bladder aspiration(SBA) is a widely accepted method of obtaining sterile urine for culture in neonates but has a relatively low success rate and a few serious complications during SBA procedure. To improve the chance of obtaining urine, we determined the ultrasonographic bladder parameters(diameters and volume) to confirm that the bladder is adequately distended for successful aspiration of... |
Urinary ascites in newborns is a rare event that usually is associated with posterior urethral valves and other obstructing anomalies of the genitourinary tract. A case of neonatal urinary ascites without genitourinary tract abnormalities is reported. This premature male neonate was treated by artificial ventilation due to respiratory distress syndrome. The umbilical artery catheter was placed without difficulties and functioned... |
Hinman syndrome is a condition caused by an incoordination between the detrusor and external urethral sphincter during bladder contraction. Manifestations include day-and-night wetting, residual urine, infected urine, vesicoureteral reflux, christmas-tree shaped bladder-wall change, and upper tract damage without neurologic lesion or anatomical obstruction. Recently, this incoordination was postulated to be due to over-compensation of the external sphincter which compensates the... |
Ceftriaxone, a third-generation cephalosporin, is a very potent, broad spectrum antibiotic commonly used in patients with meningitis, osteomyelitis, pyelonephritis, Lyme disease and many other severe infectious diseases. Up to 46% of those receiving this antibiotic develop gallbladder sludge. Most of them are asymptomatic, but a small proportion may develop right upper quadrant pain, nausea, vomiting and even cholecystitis. We report... |
Acute hemorrhagic cystitis characterized by gross hematuria and symptoms of bladder irritation occurs in children as a self-limited disease that must be differentiated from serious renal disease. We analyzed 22 cases of hemorrhagic cystitis which were managed in the Dept. of pediatrics, Kyung Hee university hospital and present the availability of bladder sonography for diagnosis of hemorrhagic cystitis and for follow-up. The... |
Since the urinary tract infection (UTI) in neonates is often associated with major urologic anomalies, early diagnosis is essential. In the screening of UTI by urine bag, contamination is a commonly encountered problem. Suprapubic bladder puncture has therefore been recommended as the best method to confirm UTI. The purpose of this study is to assess the frequency and characteristics of... |
A 14-year-old Korean boy with Addison's disease probably of tuberculosis origin is presented with a brief review of the literature. The patient was admitted to our hospital on July, 23th, 1990, because of dark brown pigmentation of the skin, mucous membrane and nail beds. On physical examination, he was moderately developed, relatively poorly nourished. Skin and mucous membranes were diffusely dark brown,... |
Addison’s disease is a rare disorder resulting from progressive adrenocortical destruction regardless of the nature of underlying process. A 5-year-old boy with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was admitted to out hospital because of poor appetite and generalized darkish brown pigmentation of skin and mucous membrane. On physical examination, skin and mucous membrane were... |
A 9-year-old girl with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was transferee! to our hospital because of darkish brown pigmentation of whole body and generalized weakness which had misunderstood cyanotic heart disease. On physical examination, she was poorly nourished and below 10 percentile in weight and height. Skin and mucous membrane were diffusely darkish brown,... |
The relative prominece of certain clinical manifestations in persons infected with salmonella forms the basis for designation of several clinical syndromes: enterocolitis (gastroenteritis), enteric fever, bacteremia, localized infection, and the chronic enteric or urinary carrier state. Enteric fever is clinical syndrome produced classically by S. typhi and also at times by S. paratyphi A, S. schottmuel- leri (formerly paratyphi B), and S. hirschfeldii (formerly... |
Kawasaki disease, first reported in Korea in 1973, is now one of the disease commonly encountered in pediatric age group. It presents systemic symptoms including abdominal ones such as pain, nausea and vomiting, etc. There have been several case reports of hydrops of the gallbladder occuring concurrently with Kawasaki disease, and the abdominal symptoms of the disease are known to correlate with hydrops of... |
The authors experienced a case of Kawasaki disease complicated by hydrops of the gallbladder in a 3-year old male patient. The main clinical features were colicky abdominal pain, vomiting, jaundice, fever and a palpable tender mass in RUQ in conjunction with the characteristic clinical manifestation of Kawasaki disease. The clinical diagnosis was confirmed by ultrasonography, and the patient was recovered by conserva- tive management without... |
We experienced 1 case of mucocutaneous lymph node syndrome complicated by aseptic meningitis, hydrops of the gallbladder and dilatation of the coronary arteries in 2 year 8 month old female infant. Her clinical synptoms, laboratory data and clinical courses were presented with brief review of the literatures. This baby admitted because of high fever and vomiting for 6 days. She had injection of... |
1) Neurological assessment has been done in children with learning disorders, who are rological problems. The high incidence of neurologic defect is thought that those children are not purely child with learning disorder but many of them are handicapped children as well as mentally retarded ones. Neurological problems they manifested are organic brain dysfunction, children with severe psychological roblem, attention... |
There are four main groups of clinical manifestations in salmonellosis, gastroenteritis。 enteric fever, localized infection, and chronic carrier state, that may occur individually, simultaneously or consecutively in the course of an infection. The authors experienced a case of salmonella gastroenteritis complicated with empyema of gall bladder in a 12-year-old male patient. The clinical diagnosis was confirmed on the operating table and... |
Acute hydrops of the gallbladder is described in one patient who had mucocutaneous lymph node syndrome. During the course of her illness, acute addominal pain, vomiting and right upper guadrant tenderness were developed. Diagnosis was readily made with ultrasonography, and the patient was followed with this te-chnique. We managed her conventionally without surgical intervention. The galbladder returned to normal size... |
A female patient with mucocutaneous lymph node syndrome is presented. During the course of her illness, she developed acute abdominal pain secondary to hydrops of gallbladder. The diagnosis was facilltated by ultrasound. We managed her conventionally without surgical intervention. It is interesting that the age of patients complicated by gallbladder hydrops is high compared with the age frequency of MCLS.... |