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A Case of Ceftriaxone-induced Pseudocholelithiasis

Journal of the Korean Pediatric Society 1998;41(6):841-843.
Published online June 15, 1998.
A Case of Ceftriaxone-induced Pseudocholelithiasis
Hong Kwon Kim1, Jeong Ho Kim1, Kyung Mo Kim1, Chong Hyun Yoon2
1Department of Pediatrics, College of Medicine, Ulsan University, Seoul, Korea
2Department of Diagnostic Radiology, College of Medicine, Ulsan University, Seoul, Korea
Ceftriaxone 치료 후에 속발한 가담석증 1례
김홍권1, 김정호1, 김경모1, 윤종현2
1울산대학교 의과대학 서울중앙병원 소아과학교실
2울산대학교 의과대학 서울중앙병원 방사선과학교실
Correspondence: 
Hong Kwon Kim, Email: 1
Abstract
Ceftriaxone, a third-generation cephalosporin, is a very potent, broad spectrum antibiotic commonly used in patients with meningitis, osteomyelitis, pyelonephritis, Lyme disease and many other severe infectious diseases. Up to 46% of those receiving this antibiotic develop gallbladder sludge. Most of them are asymptomatic, but a small proportion may develop right upper quadrant pain, nausea, vomiting and even cholecystitis. We report a case of ceftriaxone-induced pseudocholelithiasis in a 5-year-old boy. We also emphasize the fact that surgical interventions such as cholecystectomy is not necessary, because the condition may resolve spontaneously after cessation of the drug.
Key Words: Ceftriaxone, Biliary Pseudolithiasis, Pseudocholelithiasis, Gallbladder sludge


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