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Original Article
A case of IDDM associated with hypothyroidism.
Kyung Min Lee, Kuk Sin Jang, Mi Kyung Jang, Chul Zoo Jung
Clin Exp Pediatr. 1991;34(1):144-147.   Published online January 31, 1991
The authors experienced a case of insulin-dependent diabetes mellitus with hypothyroidism. We recommend that all patients with insulin-dependent diabetes mellitus be screened for thyroid mi- crosomal antibody and that those patients found to have thyroid microsomal antibody be followed annually for determination of free T4 and TSH values. We report this case with a review of related literatures.
HLA Typing, Islet Cell Antibody and C-Peptide of Insulin Dependent Diabetes Mellitus in Children.
Hyeong Rae Cho, Sei Joong Ko, Duk Hi Kim, Hyun Chul Lee, Kap Bum Huh
Clin Exp Pediatr. 1990;33(12):1705-1712.   Published online December 31, 1990
35 childhood insulin-dependent (Typel) diabetes mellitus were typed for HLA and examined for presence of islet cell antibody and level of C-peptide. The following results were obtained: 1) HLA types were present as follows; HLA A24 (9) in 58%, DR3 in 38% and DR4 in 62%. This was slightly higher than the Korean population of 38%, 7% and 48% but there was no significant difference. 2) When...
A Case of Diabetes Insipidus in a Child with Eosinophilic Granuloma of Pituitary Stalk.
Dong Hyung Kim, Eun Kyung Won, Jung Sik Min, Chang Hee Choi
Clin Exp Pediatr. 1990;33(10):1454-1460.   Published online October 31, 1990
A 12 year old girl suffering visual disturbance for 4 months, and polydipsia and polyuria for last 20 days revealed an ovoid homogeneous mass on enhanced sella turcica coronal CT scan and result of water deprivation test was compatible with that of diabetes insipidus. Subtotoal rescetion of the brownish soft mass (0.5 x 0.7 cm) of pituitary stalk was performed neurosurgically, and histologically the...
A Case of Dermatomyositis.
Pal Dong Kim, Chi Han Kwon, Eun Sook Suh, Chin Moo Kang
Clin Exp Pediatr. 1990;33(6):870-878.   Published online June 30, 1990
Dermatomyositis is a rarely recognized disorder with poor prognosis. The mortality has been decreased after the initiation of steroid for ifs treatment. Authors experienced a case of der- matomyositis responded well to prednisone therapy and developed hyperglycemia laterly. A 14 year old boy was admitted to pediatric ward with the chief complaints of progressive muscular weakness and facial rash and diagnosed as having dermatomyositis...
The Findings of 2D and M-mode Echocardiography in Young Insulin-Dependent Diabetes Mellitus.
Byoung Rei Cho, Jae Wook Ko, Young Jin Hong, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1990;33(1):88-93.   Published online January 31, 1990
Twenty-one children and young adults with Insulin-dependent diatetes mellitus and 23 control underwent 2D and M-mode echocardiography. Following results were obtained: 1) LVESD, LVEDD, EF, FS, LAD/AOD ratio, Dm of IVS and Dm of PLVWT were not significantly different in diabetics compared to control subjects. 2) In IDDM PEP was slightly increased and LVET was slightly decreased, but there was not statistical significance between the two groups. But...
A Case of Transient Neonatal Diabetes Mellitus.
Hye Hyun Kim, Kyung Ha Ryu, Keun Lee
Clin Exp Pediatr. 1988;31(10):1346-1349.   Published online October 31, 1988
Transient Neonatal D.M. is rare disease which is characterized by letharginess, dehydration and weight loss with severe hyperglycemia. It occurs frequently which small for data infant and recovers spontaneously if appropriate insulin treatment was taken. We had expirienced a case of Transient Neonatal D.M. in 15 days old female infant. The review of the literature was made briefly.
The Effect of Pertussive Vaccine & Cyclosporin on Streptozotocin Induced Diabetic Rats.
Duk Hi Kim
Clin Exp Pediatr. 1988;31(7):914-923.   Published online July 31, 1988
The injection of streptozotocin (STZ) at higher dose (60 mg/kg) to young male rats produce direct beta cell destruction and lead to insulin dependent diabetes (IDD). In contrast, the injection of multiple smaller dose of STZ (40 mg/kg/d for 5 days) produce IDD, which resembles type 1 diabetes in man. The protective effect of pertussis vaccine (PV) & cyclosporin (CA) against the develoment...
Clinical Study of Diabetes Insipidus.
Jung Bae Lee, Duk Hi Kim
Clin Exp Pediatr. 1987;30(8):882-890.   Published online August 31, 1987
From Aug. 1979 to June 1986 we reviewed 27 patients with diabetes insipidus to observe the clinical features, laboratory findings and treatment of diabetes insipidus. The results were as follows: 1) Central diabetes insipidus were 22 cases (81.5%) and nephrogenic diabetes insipidus were 5 cases (18.5%). Etiologic factors in the central diabetes insipidus included idiopathic (54.6%), craniopharyn- gioma (18.2%), germinoma (13.6%), post-encephalitis (9.1%) and Histiocytosis X...
Diagnosis and Treatment of Diabetes Insipidus in Childhood.
Yong Hoom Park, Jin Sang Son, Jeong Ok Hah
Clin Exp Pediatr. 1987;30(7):749-758.   Published online July 31, 1987
In eight cases of diabetes insipidus who were diagnosed at the pediatric department of Yeungnam University Hospital from July 1985 till May 1986, the levels of plaana AVP were measured by radioimmunoassay and the effects of various treatment were studied. In central diabetes insipidus patients basal plasma AVP level was 2.92 ±2.55 pg/ml which was significantly lower than the level of control group, 8.25...
A Study on Serum Growth Hormone in DM of Childhood.
Duk Hi Kim
Clin Exp Pediatr. 1987;30(2):175-180.   Published online February 28, 1987
The human growth hormone (hGH) levels were evaluated in 13 diabetes mellitus, 11 patients were insulin dependent diabetes (ages 2 yr 10 mo to 13 yr 14 mo), 2 patients were noninsulin dependent diabetes (age 12 yr & 12 yr 5 mo). No difference in hGH level was observed in relation to duration of diabetes. The hGH responses to glucagon 1 mg injection in...
Case Report
Three Cases of Diebetes Insipidus.
Eue Bon Koo, Hak Jun Go, Tai Gyu Whang, Soon Yong Lee
Clin Exp Pediatr. 1986;29(1):88-94.   Published online January 31, 1986
We reported three cases of Diabetes Insipidus which were characterized by polyuria and polydipsia. One case was idiopathic and two cases were associated with tuberculous meningitis and pinealoma respectively. Water restriction test and hypertonic saline infusion test revealed little change in urine volume and specific gravity but good response to intramuscular injection of pitressin in all of the three cases....
Original Article
The Effects of Cyclosporin in Treatment of Insulin Dependent Diabetes Mellitus.
Duk Hi Kim
Clin Exp Pediatr. 1985;28(6):564-569.   Published online June 30, 1985
A 2 year 10 month old girl with 6 weeks duration and 13 year 4 month old boy with 8 weeks duration were given cyclosporin for 68 days. Therapy was initiated orally at the dosage of 10 mg per kg of body per day. Blood glucose, C-peptide, cyclosporin, creatinin, BUN and transaminase were checked regularly. Cyclosporin treatment allowed two patients to...
Case Report
Three Cases of Nephrogenic Diabetes Insipitus.
Hey Sun Lee, Byoung Hai Ahn, Jong Jin Seo, Hyung Ro Moon
Clin Exp Pediatr. 1984;27(9):912-917.   Published online September 30, 1984
From July 1981 to Feb. 1983, we experienced three cases of nephrogenic diabetes insipidus in which the initial diagnostic clues were repeated episodes of unexplained fever in infancy and which were confirmed by water deprivation and pitressin tests and clinical responses to administration of hydrochlorthiazide. So we report this with some review of literatures.
Original Article
A Clinical Study on Insulin Dependent Diabetes Mellitus.
H S Kim, Y K Suh, T W Paik, Y D Kwon, C M Kang
Clin Exp Pediatr. 1984;27(9):903-911.   Published online September 30, 1984
The authors studied twelve cases of insulin dependent diabetes mellitus who were admitted to Pediatric Department of Keimyung University, Dong San Hospital from February 1975 to January 1983. Disease was developed after puberty in eight cases and effected both sexes equally and had tendency, prevalent in winter season. There was no significant family history except one case who had diabetic...
Case Report
A Case of Histiocytosis X(Hand-Schuller-Christian Syndrome).
Yeong Bong Park, Jin Heon Kim, Jong Myeon Hong, Chang Soo Ra
Clin Exp Pediatr. 1983;26(12):1209-1214.   Published online December 31, 1983
A case of histiocytosis X (Hand-Schuller-Christian syndrome) in a 3 year old girl is presented. The patients has the triad of exophthalmos, diabetes insipidus and skeletal lesions, plus hepatomegaly, wide spread pulmonary infiltration and growth retardation. The patient was treated with chlorambucil, prednisone, radiation therapy and chlorpropamide therapy for diabetes insipidus with good response. Similar cases reported in literature are briefly...
Nephrogenic Diabetes Insipidus occurred in 2 Brother.
Jin Heon Kim, Cheol Won Park, Bong Soo Lee, Chang Soo Ra
Clin Exp Pediatr. 1983;26(9):916-921.   Published online September 30, 1983
Nephrogenic diabetes insipidus is a congenital hereditary disorders in which the kidney do not respond to vasopressin, and the disease occurs principally in males and is probably inherited by Xlinked recessive mode. We experienced two cases of nephrogenic diabetes insipidus occurred in brothers. The clinical manifestations were extreme thirst and frequent urination of large volume of dilute urine, approximately 5,500ml per day with specific gravity...
A Case of Congenital Nephrogenic Diabetes Insipidus.
Jae Sook Kim, Sook Hee Kong, Choong Hee Kim
Clin Exp Pediatr. 1983;26(9):909-915.   Published online September 30, 1983
This 18/12-year old female baby was diagnosed as primary nephrogenic diabetes insipidus， whose main complaint was polydypsia and polyuria from birth, subsequently she developed failure to thrive. Family history was nonspecific. Laboratory findings revealed failure of concentrates urine with water restriction test and pitressin test. And so renal hypoplasia on the right side was revealed on retrograde pyelography and renal scan. She was...
Original Article
Clinical Observation of Juvenile Diabetes Millitus.
Hae Il Cheong, Dong Gyoon Kim, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1983;26(6):553-563.   Published online June 30, 1983
Clinical data of 33 children with juvenile diabetes mellitus who were admitted to the Seoul National University Hospital from Jan. 1967 to Feb. 1983 were analyzed retrospectively. Male to female ratio was 10:23, the mean age at onset was 6 10/12 years, and there was considerable seasonal variation with peaks in late winter and spring. Polyuria and polydipsia were noted in all cases as...
Case Report
A Case of Hand Schuller Christian Disease.
Yeon Saeng Lee, Soo Young Kim, So Kyung Park, Dong Hak Shin
Clin Exp Pediatr. 1983;26(4):392-396.   Published online April 30, 1983
Hand-Schuller-Christian disease is reactive granulomatous lesion with histiocytic proliferation, the cause of which is unknown. Recently, we experienced a case in a 3 years old female with polydipsia and polyuria. We established the diagnosis with clinical features, radiologic examination and bone biopsy- Histiologic examination of frontal bone showed mild to moderate infiltration of eosinophils， lymphocytes, plasma cells and large histioytes and fibrosis. Similiar cases reported in...
Three Cases of Insulin Dependent Diabetes Mellitus in Children.
Tae Hoon Lee, Sang Chul Park, Chang Hwi Kim, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1983;26(3):285-289.   Published online March 31, 1983
We experienced three cases of Insulin Dependent Diabetes Mellitus, which revealed fullfilling- all characteristics of clinical 技 laboratory finding during recent 3 years. Two diabetic children among three patients had developed diabetic ketoacidosis. The one of the two cases, 14 aged girl complained of dyspnea & severe emaciation. The another case, 11 year and 2 month-old boy who had cataract complained of severe epigastric pain,...
Original Article
Clinical Study of Juvenile Diabetes Mellitus.
Keun chull Choi, Seok ku Kim, Chul Lee, Myung ho Lee
Clin Exp Pediatr. 1982;25(5):489-497.   Published online May 31, 1982
We have observed 9 cases of juvenile diabetes mellitus who were admitted to Pediatrics Department of Presbyterian Medical Center in Jeon-ju, during period of 7 years and 2 months from Jan, 1974 to Mar, 1981. The following results were obtained. 1) Incidence of juvenile diabetes mellitus was 0.088% of all patients who were admitted to Pediatric Department ward during period...
Case Report
A Case of Congenital Generalized Lipodystrophy.
Woon Sik Kim, Kye Tae Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1981;24(2):173-180.   Published online February 15, 1981
A 4 year and 2 months old girl with peculiar appearance and abdominal protuberance was prese-nted. She was the 2nd full term product of a healthy, 37-year-old mother. Any history of neonatal problems couldn’t be elicited. At 1 month of age his mother began to notice loss of subcutaneous fat with prominent musculature. At 2 months of age he was...
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