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Original Article
Statistical Analysis of Death Cases in Pediatric Ward.
Kui Ae Jang, Kyeung Bae Park, Jae Ock Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(1):1-9.   Published online January 31, 1990
Statistical analysis of death cases during the 9 years from Jan. 1979 to Dec. 1987 in pediatric ward of Soonchunhyang university hospital was carried out. The following results were observed. 1) Total numbers of admission during the 9 years were 16365, of whom 296 expired. 2) Average mortality rate was 1.8% and the annual mortality rate showed decreasing tendency from 1979 to 1987. 3) In age distribution, the neonates...
A Case of Acute Rhenmatic Fever Associated with Acute Poststreptococcal Glomerulonepheitis.
Ho Kyung Choi, Dong Seok Choi, Jae Ho Lee, Young Hun Chung, Hyon Soon Lee
Clin Exp Pediatr. 1989;32(12):1744-1748.   Published online December 31, 1989
A case of acute glomerulonephritis in association with acute rheumatic fever was presented. The patient rheumatic arthritis and carditis with mitral insufficiency, who had been diagnosed as acute poststreptococcal glomeruoonephritis with non-oliguric renal failure with renal biopsy and laboratory findings. The patient was treated, and symptom and sign were improved.
The Collaborative Clinical Analysis of 985 Cases of Rheumatic Fever and Rheumatic Carditis in Children for 10 Years(1978~1987) in Korea.
Sung Ho Cha, Sang Young Jeong, Du Bong Lee, Kyong Su Lee, Sang Bum Lee, Tae Chan Kwon, Young Chang Tockgo, Chang Sung Sohn, Keun Chan Sohn, Young Jin Hong, Chan Young Kim, Chang Yee Hong, Yong Soo Yun, Jung Yun Choi, Chang Hwi Kim, Chul Ho Kim, Tae Ju Hwang, Jae Suk Ma, Chan Uhul Joo, Kyoo Hwan Rhee, Hahng Lee
Clin Exp Pediatr. 1989;32(12):1621-1631.   Published online December 31, 1989
Acute rheumatic fever and rheumatic carditis were still important disease of the acquired heart disease in children and adults, in spite of improving socioeconomic status in Korea. Recently, many outbreaks of acute rheumatic fever have been reported in the papers from developed countries. We should be aware of such outbreaks of acute rheumatic fever and should pay attention to their treatment of the patients...
Effects of long-term anticonvulsant therapy of thyroid function.
Sei Joong Ko, Duk Hi Kim, Chang Jun Coe
Clin Exp Pediatr. 1989;32(11):1533-1539.   Published online November 30, 1989
Serum concentrations of total triiodothyronine (T3) and thyroxine (T4) as well as serum thyroid- stimulating hormone (TSH) were measured in 108 patients with childhood epilepsy taking anticonvul- sants and in 54 normal healthy children as control group. Of these 108 patients, 23 were treated with carbamazepine alone, 17 were phenytoin alone and the rest 68 were treated with combination of two or more drugs...
Role of aldosterone on the minimal change nephrotic syndrome in children.
Soon Wha Kim, Myung Ik Lee, Don Hee Ahn
Clin Exp Pediatr. 1989;32(11):1526-1532.   Published online November 30, 1989
We studied 11 cases of minimal change nephrotic syndrome randomly selected among 16 cases of minimal change nephrotic syndrome who were proved by kidney biopsy at department of pediatrics, National Medical Center during the period of January 1985 through December 1987. These patients were studied serially at 3 different stages in their clinical course. These were stages of edema formation, diuresis and remission, respectively. The...
The clinical evaluation for children with orthostatic proteinuria.
Chan Sung Lee, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1989;32(11):1520-1525.   Published online November 30, 1989
Total of eighteen children with orthostatic proteinuria were evaluated for clinical characteristics. The development of renal or urologic diseases were monitored on these subjects for 1 year. The results were as following; 1) The number of children with transient orthostatic proteinuria and fixed orthostatic proteinuria were 7(39%) and 11(61%), respectively. 2) In children with fixed and reproducible orthostatic proteinuria, mild proteinuria were noted in 73% but no massive...
Asymptomatic human rotavirus infections during infancy and preschool period.
Hye Lim Jung, Byoung Hoon Yoo, Tae Sub Shim
Clin Exp Pediatr. 1989;32(11):1482-1488.   Published online November 30, 1989
Asymptomatic human rotavirus (HRV) infection rate was studied by comparing the rate of HRV excretion in diarrhea cases with that in nondiarhea group of children under preschool age. HRV antigen in stool was detected by enzyme-linked immunosorbent assay (ELISA) from children under 6 years of age who were admitted to Pediatric Department of Chung-Ang University Medical Center from November 1988 to mid-April 1989. 1) HRV antigen...
The Effect of Oral Vitamin E on Hemolytic Anemia of the Premature Infants.
Hwa Kyoung Oh, Kwang Sik Yoo, Yong Sil Chi, Myung Jin Kim, Mi Na Lee
Clin Exp Pediatr. 1989;32(11):1469-1473.   Published online November 30, 1989
The study was designed to evaluate the effect of vitamin E on hemolytic anemia of premature infants. Sixty infants delivered in Cheil Hospital from March 1987 to December 1988 with birth weight below 2500 gm or gestational age below 37 weeks were studied. Thirty infants received oral vitamin E 25 IU/day until their birth weight doubled. Thirty infants served as control. The results were...
Three Cases of Typhlitis during Treatment for Acute Myelocytic Leukemia in Children.
Soon Mee Park, Il Soo Ha, Hoan Jong Lee, Jeong Kee Seo, Hyo Seop Ahn, Kyung Mo Yeon
Clin Exp Pediatr. 1989;32(10):1455-1462.   Published online October 31, 1989
Typhlitis is a rare necrotizing colitis in which inflammation is confined to cecum. It occurs during chemotherapy for malignancies, in terminal stage of aplastic anemia, in transplant patients. The pathogenesis of typhlitis has included leukemic infiltration of the bowel, thrombocytopenia, direct toxic effects of chemotherapy, steroid, bacterial invasion of the bowel wall secondary to neutropenia and alteration of the bowel flora by broad-spectrum antibiotics....
A case of Idiopathic Crescentic Glomerulonephritis.
Mi Kyung Kim, Hyun Joo Choi, Seung Joo Lee, Ok Kyung Kim
Clin Exp Pediatr. 1989;32(10):1435-1441.   Published online October 31, 1989
Idiopathic crescentic glomerulonephritis is a very rare disease especially in children with poor prognosis. We experienced a case of idiopathic crescentic glomerulonephritis in a 4-year-old male patient who presented initially with a nephrotic syndrome and progressed to a rapidly progressive glomerulonephritis. We review literatures briefly.
Selectivity Index of Proteinuria in Childhood Minimal Change Nephrotic Syndrome.
Cheol Ho Lee, Young Seo Park, Kwang Wook Ko
Clin Exp Pediatr. 1989;32(10):1384-1390.   Published online October 31, 1989
The selectivity indices (S.I.) of proteinuria in 120 biopsy proven minimal change nephrotic syn- drome (MCNS) children who were admitted to Seoul National University Childern’s Hospital from January 1976 to June 1988 and followed up for more than 1 year from onset of disease, were analyzed in relation to clinical findings, histopathologic features and steroid responsiveness. The results were as follows: 1) The mean age at...
Peptic Ulcer in Infants and Children.
Bo Young Lee, Jae Kyoun Rhin, Ki Sup Chung
Clin Exp Pediatr. 1989;32(10):1360-1368.   Published online October 31, 1989
The authors clinically observed 60 patients with peptic ulcers who had been admitted to Severance Hospital, Yonsei University College of Medicine during the 9 year period from May 1979 to May 1988. The results were as follows: 1) Age and sex incidence of peptic ulcer patients from 5 months old to 17 years old showed that males predominated in a proportion of 1.5:1 and 88.3%...
A Case of Early Infantile Epileptic Encephalopathy with Suppression-burst.
Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1320-1323.   Published online September 30, 1989
The authors experienced a case of 45-day-old female newborn infant who showed the intractable tonic spasms with series formation and hypotonia. We diagnosed it through the evaluation of the clinical, radiological features including brain CT and electroencephalogram. The suppresion-burst pattern in EEG and clinical features aid to the confirmation of the diagnosis. A brief review of the related literature were made.
A Case of Myelodysplatic Syndrome.
Sun Bok Suh, Chang Ok Soh, Sang Hoon Lee, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1989;32(9):1314-1319.   Published online September 30, 1989
We have experienced a case of myelodysplastic syndrome (RAEB) in an 11-year-old boy with the complaints of pallor and petechiae for 1 month. After diagnosis, improvement was remarkable with chemotherapy of low dose cytosine arabinoside but the RAEB was transformed to acute myeloblastic leukemia 4 months after treatmemt. Anti-leukemic therapy was tried but induction of remission was failed and he was died of sepsis...
Percutaneous Balloon Valvuloplasty in Children with Pulmonary and Aortic Valvular Stenosis.
Chan Uhng Joo, Jung Soo Kim, Ho Yunh Song
Clin Exp Pediatr. 1989;32(9):1224-1231.   Published online September 30, 1989
Pulmonary and aortic valvular stenosis were relieved by percutaneous balloon valvuloplasty during cardiac catheterization on 14 children aged 22 months to 18 years. Before dilatation the transpulmonary systolic pressure gradients ranged from 43 mmHg (mean 87. 8 mmHg) in children with pulmonary valvular stenosis. There were significant reduction in the transpulmonary systolic pressure gradient (mean 33.1 mmHg) immediately after balloon valvuloplas- ty except one patient...
Analysis of Asymptomatic Proteinuria in School Children.
Chong Guk Lee, Tae Sub Shim, Dong Hwan Lee, Yong Soo Yun, Chang Jun Ko, Sa Jun Chung, Hyun Soon Lee, Sung Jae Suh, Pyung Nam Kim
Clin Exp Pediatr. 1989;32(9):1187-1194.   Published online September 30, 1989
Uriary mass screening program for the detection of proteinuria had been performed for a school- age population in the city of Seoul since 1981. Annually, about half million students, who comprised 3 different age group, corresponding to the averages of 11，14, and 17 years, had been examined. A systematic clinical evaluation was designed for students with proteinuria identified in the mass screening through ’87...
Hypertrophic Cardiomyopathy in Infant of Diabetic Mother.
Jeong Sam Jeon, Soo Chun Kim, Chong Woo Bae, Sung Ho Cha, Chang Il Ahn
Clin Exp Pediatr. 1989;32(8):1138-1143.   Published online August 31, 1989
Generally, infant of diabetic mother (IDM) have complex multisystems disease resulting in a high incidence of perinatal morbidity and mortality. Hypertrophic cardiomyopathy (HCM)-IDM appears as the early onset, transient and non-familial cariomyopathy in neonatal period. The etiology of the left ventricular outflow obstruction in these neonates is not clear. But, it is possible that the asymmetrical septal hypertrophy was a manifestation of the generalized...
Changes of Plasma Atrial Natriuretic Peptide and Antidiuretic Hormone in Congenital Heart Disease.
Sun Jun Kim, Jong San Lee, Chan Uhng Joo, Dae Yeol Lee, Jung Soo Kim
Clin Exp Pediatr. 1989;32(8):1106-1116.   Published online August 31, 1989
Human atrial myocytes secrete atrial natriuretic peptides (ANP) into the plasma, which causes rapid and marked natriuresis, diuresis and vasorelaxation. The releases of renin, aldosterone, and antidiuretic hormone are inhibited by ANP in vivo and in vitro experiments. Various atrial natriur- etic peptides were isolated and synthesized. Plasma ANP concentrations usually elevated in conges- tive heart failure, chronic renal failure, pulmonary arterial hypertension, tachyarrhythmia,...
Serum LDH and Isoenzyme Activity in Children with Respiratory Diseases.
Kyoung Min Ann, Young Kyoo Shin, Kwang Chul Lee, Ji Tae Choung, Young Chang Tockgo, Pyung Hwa Choe
Clin Exp Pediatr. 1989;32(8):1051-1056.   Published online August 31, 1989
LDH which are widely distributed in mammalian tissues, being rich in myocardium, kidney, liver and muscle, and which is well known to catalyzes the reversible oxidation of lactate to pyruvate. We investigated serum LDH & Isoenzyme changes in 317 cases of children with respiratory disease and in 117 cases of healthy children as control. The objectives of this study were to ascertain whether serum...
A Case of Cytophagic Histiocytic Panniculitis.
Hyung Keun Nam, Byong Rai Cho, Don Hee Ahn, Keun Chan Sohn, Jin Hee Sohn
Clin Exp Pediatr. 1989;32(7):995-1000.   Published online July 31, 1989
Cytophagic histiocytic panniculitis is a chronic, benign, visceral and cutaneous histiocytic (cyto- phagic) paniculitis, progressing to liver dysfunction, jaundice and a terminal hemorrhagic diathesis. We have experienced a case of cytophagic histiocytic panniculitis in an 11 year old male who had developed recurrent fever and subcutaneous nooules since infancy, progressing to liver dysfunction, jaundice and hemorrhagic diathesis. The noaular biopsy also showed a characteristic...
A Case of Peutz-Jeghers Syndrome.
Ick berm Park, Sung guen Oh, Jung suk Ko, Sang hyun Byun, Kyu chul Choeh
Clin Exp Pediatr. 1989;32(7):990-994.   Published online July 31, 1989
This is a report of our experience of Peutz-Jeghers syndrome in a 14 year old girl having family history. She was admitted with complaints of crampy abdominal pain and vomiting, and showed melanotic pigmentation on the lips, face around nose, oral mucosa around molar areas, fingers and toes. Colon study revealed multiple polyposis in colon and small bowel. In family, her father has melanotic...
Late Infantile Metachromatic Leukodystrophy-Arylsulfatase A Assay in 24h Urine.
Hong Jin Lee, Yong Joon Shin, Yong Seung Hwang, Hyung Ro Moon, Jeong Seon Seo
Clin Exp Pediatr. 1989;32(7):978-983.   Published online July 31, 1989
A 2 year 5 month old female infant with late infantile metachromatic leukodystrophy was diagnosed by typical clinical and laboratory findings and Arylsulfatase A assay in 24h urine. The patient’s mother was confirmed as a heterozygote by Arylsulfatase A activities in 24h urine which was about one half of normal control groups.
Statistical Analysis of Pediatric Diseases in Korea(1987).
Kyong Su Lee, Ki Sup Chung, Ki Yang Ryoo, Woo Gill Lee, Sang Bum Lee, Se Jin Kang, In Kyung Sung
Clin Exp Pediatr. 1989;32(7):885-896.   Published online July 31, 1989
The Korean pediatric association is conducting the analysis of disease patterns of children by the body organ system. For the purpose of assessing the disease patterns in patients of the pediatric age in Korea, we performed a statistical analysis of diseases of patients admitted to the department of pediatrics in 36 hospitals having pediatric residency programs in 1987. The results obtained were as follows, 1) Total...
A Case of Febrile Ulceronecrotic Pityriasis Lichenoides et Varioliformis Acuta.
Jin Hyeon Park, Hae Sung Cho, Kyu Jin Oh, Hee Jung Kwon, In Sil Lee, Gyae Yong Song
Clin Exp Pediatr. 1989;32(6):866-871.   Published online June 30, 1989
Febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta is a severe form of pityriasis lichenoides et varioliformis acuta characterized by the sudden polymorphous eruptions composed of diffuse coalescent macule, papule, vesicle, hemorrhagic vesicle and reddish brown crust on the neck, trunk, axilla, both extremities, and systemic symptoms such as fever and malaise. We have experienced a case of febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta which...
A Case of Laurence-Moon-Biedl Syndrome Including Diabetic Mellitus.
Byoung Hoon Lee, Byung Rai Cho, Myoung Ik Lee, Keun Chan Sohn, Hyung Joon Yoo
Clin Exp Pediatr. 1989;32(6):857-861.   Published online June 30, 1989
Laurence-Moon-Biedl syndrome has a varialbe phenotype and includes obesity, mental deficiency, retinitis pigmentosa, polydactyly and hypogonadotrophic hypogonadism. This report concerns a rare case of a 13-year-old girl having diabetic mellitus with Laurence-Moon-Biedl syndrome. The relevant literature was reviewed.
Serum IgE Level in Patients with Minimal Change Nephrotic Syndrome.
Sung Oh Kim, Hee Jung Ahn, Seong Ho Kim, Woo Gill Lee
Clin Exp Pediatr. 1989;32(6):789-796.   Published online June 30, 1989
It has been reported that many patients with minimal change nephrotic syndrome(MCNS) have high serum IgE level, but its significance has not been disclosed yet. In this study, serum levels of IgE were evaluated in different stages of the disease with or without treatment in 26 MCNS(proven by renal biopsy) patients admitted to the Department of Pediatrics Hanyang University Hospital from January, 1980 to...
A Case of Thiopental-Induced Hemolytic Anemia After Open Heart Surgery.
J H Lee, K H Cho, K C Lee, J W Lee, S K Kim
Clin Exp Pediatr. 1989;32(5):730-734.   Published online May 31, 1989
We experienced a case of thiopental-induced hemolytic anemia with impairment of renal function after open heart surgery. The diagnosis was suggested by clinical features, CBC, urinalysis, transfusion reaction study and chemistry, and finally established by immunohematologic study. We detected antibody against thiopental in the patient’s serum (end-titer:1:16). The review of literature was made briefly.
A Case of Congenital Hypoplastic Anemia.
Jae Wook Lee, Soon Ok Kang, Jee Sung Kim, Im Ju Kang, Seh Yoon Jeong
Clin Exp Pediatr. 1989;32(5):724-729.   Published online May 31, 1989
We observed a case of congenital hypoplastic anemia in a 6 months old female patient who was admitted because of severe anemia & failure to thrive and diagnosed through bone marrow aspiration. This patient had reticulocytopenia & increased M:E ratio (57.5:1). His hematologic improvement was followed by administration of prednisone. A brief review of related literature was made.
A Case of Eczema Herpeticum Occurring in Atopic Dermatitis.
Eun Young Choi, Min Sik Kim, Hey Sun Lee, Young Min Ahn
Clin Exp Pediatr. 1989;32(5):695-699.   Published online May 31, 1989
We have experienced an 11-month-old male who had suffered from atopic dermatitis and subsequent eczema herpeticum which was confirmed by Tzank test and successfully treated with Acyclovlr. We report this case with a brief review of related literature.
Cyclophosphamide-Induced Hemorrhagic Cystitis in Acute Lymphocytic Leukemia and Non-Hodgkin Lymphoma.
Young Seo Park, Il Soo Ha, Soon Ki Kim, Hae Il Jung, Yong Choi, Hyo Seop Ahn
Clin Exp Pediatr. 1989;32(5):665-669.   Published online May 31, 1989
We studied the cyclophosphamide-induced hemorrhagic cystitis in 72 cases of acute lymphocytic leukemia or Non-Hodgkin lymphoma, which had been treated at Seoul National University Children' s Hospital from June, 1985 to May, 1988 1) Among 72 cases treated with cyclophosphamide, 6 cases(12.8%) developed hemorrhagic cystitis in 47 cases of acute lymphocytic leukemia and 2 cases(8.0%) in 25 cases of Non-Hodgkin lymphoma. 2) The development of...
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