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Original Article
Effect of Perinatal Asphyxia and Gentamicin on Urinary β2-microglobulin Concentration and Renal Function in Fullterm Neonates
Hoo Jae Hann, Seung Joo Lee
Clin Exp Pediatr. 1994;37(7):976-985.   Published online July 15, 1994
Perinatal asphyxia can cause ischemic injury to immature kidney of neonates. Proximal renal tubule is the most sensitive area, showing various manifestations ranging from mild reversible injury to irreversible tubular necrosis. Aminoglycosides can be nephrotoxic in therapeutic range in immature or damaged kidney. These are the very important factors to be taken into corsideration on fluid therapy and nephrotoxic drugs...
Atrial Flutter Conversion in Infants and Children Using Transesophageal Atrial Pacing
Jae Kon Ko, Seoug Ho Kim, Eun Jung Bae, I Seok Kang, Heung Jae Lee
Clin Exp Pediatr. 1994;37(7):969-975.   Published online July 15, 1994
Atrial flutter is an infrequent, but potentially unstable tachyarrythmia that occurs in pediatric ages. Transesophageal atrial pacing was used for treatment of 10 episodes of atrial flutter in 7 patients. At the time of atrial flutter conversion, patients were 6 days to 14 years old. 6 patients had associated with congenital heart disease. The atrial cycle length of atrial flutter ranged from...
Pheochromocytoma in Children
Tae Sue Ha, Jae Hong Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hyung Ro Moon, Gui Won Park
Clin Exp Pediatr. 1994;37(7):961-968.   Published online July 15, 1994
We Reviewed 10 hypertensive children with pheochromocytoma retrospectively and the following results were obtained. 1) Out of 10 patients, 7 were male and 3 female. Age ranged from 5.5 years to 13.8 years and their median age was 9.9 years. 2) They complained of sweating, lethargy, headache, or chest pain and so on, Hypertension were noticed in all patients. Heart murmurs were...
Study on Iron Deficient State in the Female Adolescent Athletes
Pil Seob Shim, Ja Hyun Park, Dong Gun Park, Kwang Chul Lee, Young Chang Tockgo
Clin Exp Pediatr. 1994;37(7):953-960.   Published online July 15, 1994
Iron deficient state occurs commonly in the athlets, and the cause may be cause may be inadequate iron intake, loss of iron from sweat, blood loss of gastrointestinal tract, and hematuria. The age of the athletes ranged from 11 to 17 years old. I messured red blood cell count, hemoglobin, hematocrit, and related hematologic factors in the 32 adolescent female...
Nonspecific Bronlchial Reactivity Determined by Tidal Breathing Method and Chest Auscultation - A Comparison with Dosimeter Method -
Soo Ahn Chae, Young Yull Koh
Clin Exp Pediatr. 1994;37(7):946-952.   Published online July 15, 1994
As a preliminary step to determine if we can perform methacholine challenge test in young children, we investigated the feasibility of modified technique of methacholine challenge test in which tidal breathing and chest auscultation were used instead of dosimeter and measurement of lung function in older children. The results are as follows 1) Values of PC20 measured by the tidal breathing...
Meta-analysis of Impact of Neonatal Intensive Care on Neurodevelomental Outcome of Very Low Birth Weight Infants
Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1994;37(7):937-945.   Published online July 15, 1994
We analyzed neurodevelopmental outcome data of 36 selected studies. Data of individual studies were pooled by birth weight group: <800g, <1,000g, <1,500g and by time period of birth year: Period I(pre-intensive care era), 1960-67:Period II(beginning period of intensive care), 1968-76:and Period III(established period of intensive care), 1977-87. In all weight groups, survival and intact outcome rates based on live birth have...
The Biochemical and Bacteriological Study of the Umbilical Venous Blood for Autologous Transfusion in Neonates
Son Moon Shin, Kwang Hae Choi, Hyun Mo Gu, Jeong Ok Hah
Clin Exp Pediatr. 1994;37(7):928-936.   Published online July 15, 1994
This study was conducted to investigate the safety of the umbilical venous blood for antologous transfusion in the premature newborn babies. Umbilical venous blood was collected with aseptic technique immediately after delivery from 270 healthy mothers admitted to the Yeungnam University Hospital between March 1, 1992 and August 31, 1992. The volume of the blood and the time taken for...
Normal Values for Neonatal Periumbilical Skin Length
Young Pyo Chang, Hyung Suk Lim, Hye Won Park, Woong Huem Kim, Hee Ju Kim
Clin Exp Pediatr. 1994;37(7):924-927.   Published online July 15, 1994
Malformations of umbilicus are feature of many dysmorphic syndromes and the measurement of periumbilical skin length should be considered as the basic step in the description of the umbilical malformations. So, we measured the periumbilical skin length in the 103 normal neonates and obtained the following results. 1) The means(+SD) of the periumbilical skin length were the 11.7mm(+3.0)in the cranial site...
Association of Allergic Disease with the Sinusitis in Children
Heung Keun Oh, Koo Pong Jung, Hyun Sung Park, Chang Ok Soh, Jin Young Jung
Clin Exp Pediatr. 1994;37(7):913-923.   Published online July 15, 1994
Sinusitis manifested as symptomatic imflammation of the paranasal sinuses is a common pediatric diagnosis. Many studies have focused more directly on the question of relationship between allergy and sinusitis but the relevance of the relationship between allergy and sinusitis still needs further examination. The purpose of this study is to assess of relationship of allergy to extent or severity of...
Protective Effect of Breast Feeding for Infection
Jin Kyung Jung, In Nam Kang, Dong Ju Sin, Doo Bong Lee
Clin Exp Pediatr. 1994;37(7):906-912.   Published online July 15, 1994
A Comparative study was retrospectively performed with 374 infants in order to find protective effect of breast feeding for infection. This study shows that breast feeding protect infant against gastrointestinal and respiratory infcttion. Breast feeding offers advantage by reducting gastraintestinal and respiratory infection when they should maintain breast feeding for at least three months. 1) First year morbidity increased with extent of artificial...
Significance of Urinary Interleukin 6 Level in Mesangial Proliferative Glomerulonephritis in Children
Byeong Ho Kang, No Hyun Kim, Woo Yeong Chung, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1994;37(7):900-905.   Published online July 15, 1994
By animal experiments in rat, it has been known that Interleukin-6(IL-6) is secreted from renal mesangial cells and is an autocrine growth factor for the proliferation of mesangial cells. According to these facts, several studies have been tried for its clinical usefulness by measuring their serum or urinary IL-6 in glomerulonephritis patients with mesangial proliferation. The authors measured urinary IL-6...
Unusual Presentation of Kawasaki Disease Complicated by Coronary Aneurysms
Young-Ah Lee, In-Sook Park, Young-Hwue Kim, Hyung-Nam Moon, Chang-Yee Hong
Clin Exp Pediatr. 1994;37(7):890-899.   Published online July 15, 1994
Patients with atypical or incomplete Kawasaki disease are at same risk for development of coronary artery complications as typical Kawasaki disease. In this communication we report six patients with unusual presentation of Kawasaki disease complicated by coronary artery aneurysms, in whom correct diagnosis were not made in time for proper treatment. One of these patients died from massive myocardial ischemia...
A Clinical Observation on Lupus Nephritis in Children
Kang Mo Ahn, Jae Sung Ko, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hee Joo Kim
Clin Exp Pediatr. 1994;37(6):842-849.   Published online June 15, 1994
We reviewed the clinical features, histrologic patterns and clinical courses of 30 children with lupus nephritis retrospectively, and the results were summerized as follows; 1) The male to female ratio was 1:2.8, and the mean age at the onset was 108/12 years. 2) The clinical symptoms were diverse, and malaise, weight loss, anorexia, fever and malar rash were the most frequent findings. 3)...
Normal Blood TSH, T4 Levels in Neonates as Determined by Screening Test
In Ah Cha, Kwang Sin Kim, Kyoung Sim Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(6):832-841.   Published online June 15, 1994
In 1,146 term neonates without perinatal problems who were born in kwangju Christian Hospital, blood TSH levels were measured by immunoradiometric assay. In 397 term neonates among them, blood T4 levels were measured by radioimmunoassay in same specimens. 1) In normal neonates aged 3~5days, 6~10days, 11~20days and 21~28days, the TSH levels were 8.885.21(meanSD), 9.44¡¾5.16, 9.69¡¾4.98, 11.963.75IU/ml and the T4 levels were...
Infectious Mononucleosis in Children
Woong Young Moon, Sei Ho Oh, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
Clin Exp Pediatr. 1994;37(6):822-831.   Published online June 15, 1994
We reviewed th eclinical findings of infectious mononucleosis and performed Epstein-Barr virus (EBV) serologic antibody tests in infectious mononuleosis and healthy group. One group was 18 cases of children, diagnosed as infectious mononucleosis who had been admitted to the department of Pediatrics. Asan Medical Center for two years and eight months. From November, 1989 to June, 1992. Another group was...
Breast Feeding and Lower Respiratory Tract Illness in the First Year of Life
Jung Ja Jun, Soo Am Jung, Ghee Am Jung, Du Bong Lee
Clin Exp Pediatr. 1994;37(6):816-821.   Published online June 15, 1994
Breast feeding is one of many factors that have been asociated with the development of lower respiratory tract illnesses. To assess the relation between breast feeding and subsequent experience of lower respiratory tract illness, we performed this study, retrospectively, on 366 infants who had been admitted to the pediatric ward, St. Francisco General Hospital, or had been brought to the...
Rapid Detection Test for Streptococcus pyogenes in Normal Carriers of Group A Beta-Hemolytic Streptococci
Sung Ho Cha, Seon Ju Kim
Clin Exp Pediatr. 1994;37(6):812-815.   Published online June 15, 1994
Streptococcus pyogenes has been regarded very importantly because of its severe sequelae, namely rheumatic fever and acute glomerulonephropathy. Rapid tests to identify this organism have been studied widely in developed countries in 1980s. We proceeded the rapid test(A Strept ADTM, Denka Seiken Co., Japan) of S. pyogenes on 141 children who were known to be carriers of this organism to...
Prevalence of Epstein-Barr Virus (EBV) Antibody in Korean Children
Sei Ho Oh, Young Ah Lee, Woong Young Moon, Tae Sun Won, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
Clin Exp Pediatr. 1994;37(6):804-811.   Published online June 15, 1994
Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15...
Clinical Study on Chronic Granulomatous Disease (CGD) -Occurrence in Siblings-
Yong Hoon Jun, Sung Won Yang, Dong Wook Kim, Hoan Jong Lee, Joong Gon Kim
Clin Exp Pediatr. 1994;37(6):794-803.   Published online June 15, 1994
To analyse the age of onset, etiologic microorgnisms, clinical manifestations, managements and genetic variation of chronic granulomatous disease, the authors reviewed four patients who were diagnosed as CGD at Department of Pediatrics, Seoul National Univesity Children's Hospital. They were siblings in relationship-two of them were brothers, the others wete brother-sister. The results were as follows; 1) Initial manifestations developed within 1...
Clinical Studies on Risk Facotrs of Recurrnces after first Febrile Convulsions in Infancies and Early Childhood
Hee Kyung Chun, Hyun Ki Joo, Mi Soo Ahn, Ji Sub Oh
Clin Exp Pediatr. 1994;37(6):786-793.   Published online June 15, 1994
The aim of this study was to evaluate the risk factors of recurrences after their first febrile convulsions in infants and young children. Dlinical studies were made on 187 cases of febrile convulsions who were admitted to the department of pediatrics of Wallace Memorial Baptist Hospital from March, 1990 to December, 1992 1) 63 cases of 187 cases had recurrences after their...
Intraventricular Hemorrhage in Full-Term Neonate
Myoung Bae Jeon, Kook In Park, Choon Sik Yoon, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1994;37(6):776-785.   Published online June 15, 1994
Intraventricular hemorrhage is a common hemorrhagic cerebral disorder in premature, but occurs much less frequently in the full-term newborn. In order to obtain documentation of clinical and ultrasonographic characteristics of intraventricular hemorrhage in full-term, we performed cerebral ultrasonography on 602 newborn infants who had been admitted to neonatal intensive care unit at the Deppartment of Pediatrics, Yonsei University College of...
A Clinical Study on Chronic Hepatitis b in the Children
Bon Su Koo, Han Sang Joo, Yung Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1994;37(6):767-775.   Published online June 15, 1994
The author observed clinical study and response of -interferon treatment of 43 cases of chronic hepatitis who were admitted to Department of Pediatrics Pusan National University College of Medicine during the period of 4 year 6 months from Jenuary, 1988 to Jun, 1992. The results were as follows: 1) Of 43 patients with chronic hepatitis CPH was 17 cases (39.5%) and CAH...
Serial M-mode Echocardiographic Assessment of Left Ventricular Function in Kawasaki Disease
Byung Ho Choi, Jin Kyung Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1994;37(6):759-766.   Published online June 15, 1994
To investigate the effect of kawasaki disease on left ventricular function, we studied 92 patients with Kawasaki disease at initial visit, after 3 months (78 patients) and after 1 year (9 patients). Using serial M-mode echocardiogram, we obtained LVD(d) (left ventricular internal dimension at end diastole), LVD(s)(left ventricular internal dimension at end systole), FS(fractional shortening), ET(ejection time), VmCF(mean velocity of circumferential...
Cricopharyngeal Incoordination in Infancy
Yong Joo Kim, Jeong Kee Seo
Clin Exp Pediatr. 1994;37(6):752-758.   Published online June 15, 1994
Cricopharyngeal incoordination of infancy is a rare disease, characterized by difficult swallowing soon after birth. Regurgitation, frequent choking and aspiration with deglutition, recurrent aspiration pneumonia, and to-and-fro movement of the contrast medium in the posterior pharynx on upper esophageal cineroentgenography. Clinical investigation was performed in the infants who were admitted due to difficult swallowing, reguritation, and recurrent pneumonia from March 1,...
Evaluation of Fever Reducing Methods in Children
Soo Young Lim, Hwa Jeong Lee, Seung Hee Mok, Heui Jeong Kwon, In Sil Lee
Clin Exp Pediatr. 1994;37(6):746-751.   Published online June 15, 1994
The efficacy of acetaminophen, sponging plus acetaminophen, and sponging alone as method of lowering body temperature was compared in 108 children aged 8 weeks to 5 years who presented with an axillary temperature of 38.5C or greater during the period from January 1993 to April 1993. The following results were obtained. 1) The male to female ratio was 2.5:1 and clinical diagnosis...
Risk Factors for Hyperglycemia in Children with Leukemia Receiving L-asparaginase
Min Joong Kwon, Ho Sung Kim, Kir Young Kim, Duk Hi Kim
Clin Exp Pediatr. 1994;37(6):740-745.   Published online June 15, 1994
Hyperglycemia is a well-recognized side effect of L-asparaginase in remission induction therapy of acute lymphocytic leukemia. Since hyperglycemia has preceded fatal diabetic ketoacidosis or hyperosmotic nonketotic coma in some patients, early detection and treatment of this complication are important. We determined retrospectively the risk of hyperglycemia in 117 patients with leukemia who had received L-asparaginase (& prednisolone). The results were as...
Occult Mediastinal Ganglioneuroblastoma Presenting with Myoclonic Encephalopathy as Paraneoplastic Syndrome
Hahng Lee, Dong Ki Han, Jae Won Oh, In Joon Seol, Eun Kyung Hong, Seok Chol Jeon
Clin Exp Pediatr. 1994;37(5):695-700.   Published online May 15, 1994
Ganglioneruroblastoma and neuroblastoma are among commonest types of childhood malignancy and a number of unique paraneoplastic syndromes have been associated with both localized and disseminated neuroblastoma. The coincidence of neuroblastoma and myoclonic encephalopathy or other paraneoplastic syndromes occurs relatively rare, and therefore, failure to recognize this association could result in delays in both diagnosis and treatment, and the result...
The Clinical Study of 10 Cases of Tsutsugamushi Fever
Dong Gyu Lee, Sung Hak Kim, Byung Keun Han, Kyung Ho Lee, Cheol Hee Hwang, Moon Ki Cho
Clin Exp Pediatr. 1994;37(5):689-694.   Published online May 15, 1994
In Korean, there has been an increasing concern on rickettsiosis as a possile common cause of unkonwn febrile illness since Tsutsugamushi fever among koreans was reported first in1986. We experienced 10 cases of Tsutsugamushi fever ocurring in the Mokpo area during the period of 3 months(Oct. to Dec.) in 1990, which were diagnosed clinically and serologically by...
Normal Predicted Values of Pulmonary Function Test in children
In Ah Cha, Kwang Sin Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(5):672-688.   Published online May 15, 1994
An objective evaluation of the degree of respiratory impairment in children depends on the establishment of standards of normal function. In addition to sex and growth, various factors such as race and geography have been shown to be important determinants of lung function. The purposes of this paper are to report the result of lung function tests performed on a...
The Effect of Cranial Irradiation on Growth of Children with Lymphatic Origin Tumors
Jin Seoup Jung, Yon Sook Rho, Sang Woo Kim
Clin Exp Pediatr. 1994;37(5):666-671.   Published online May 15, 1994
A retrospective study was conducted to investigate the effects of CNS prophylaxis with 1,800cGy cranial irradiation on standing height growth of children with acute lymphoblastic leukemia(ALL). Seventeen longterm survivors (DFS over 5 years) of ALL and Non-Hodgkins Lymphoma who had been admitted at pediatric department of Inje University Seoul Paik Hospital from January 1982 to September 1988 were studied. The long term...
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