| Rapid Detection Test for Streptococcus pyogenes in Normal Carriers of Group A Beta-Hemolytic Streptococci |
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Sung Ho Cha1, Seon Ju Kim2 |
1Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea
2Department of Clinical Pathology, Capital Armed Forces Hospital, Seoul, Korea |
| A군 베타 용혈성 연쇠구균 보균자를 대상으로 Streptococcus pyogenes검출을 위한 신속한 검사 |
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차성호1, 김선주2 |
1경희대학교 의과대학 소아과학교실
2국군수도병원 임상병리과 |
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| Abstract |
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Streptococcus pyogenes has been regarded very importantly because of its severe sequelae, namely rheumatic fever and acute glomerulonephropathy. Rapid tests to identify this organism have been studied widely in developed countries in 1980s. We proceeded the rapid test(A Strept ADTM, Denka Seiken Co., Japan) of S. pyogenes on 141 children who were known to be carriers of this organism to evaluate whether the rapid test could be used at the pediatric office base. Throat cultures were taken simultaneously to evaluate the efficacy of this rapid test. The test showed very low sensitivity of 17% (13/14) and high specificity of 99% (65/66). The positive predictive value was 93% (13/14) and negative predictive value 51% (65/127) respectively. Most of the positive results of rapid test have been agreed with the actual number of colonies on the throat culture. The reasons for the low sensitivity and negative predictive valure of the rapid test should be discovered and supplemented if it could be applicable to the pediatric office and accurate evaluation of the rapid test in patients with acute pharyngitis is needed. |
| Key Words:
Dtreptococcus pyogenes, Rapid test |
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