• Search
  • Advanced Search

Original article

  • HOME
  • ARTICLE CATEGORY
  • Original article
Article category
Original Article
Outcome and risk factors of pediatric hemato-oncology patients admitted in pediatric intensive care unit
Bo Eun Kim, Eun Ju Ha, Keun Wook Bae, Seongguk Kim, Ho Joon Im, Jong Jin Seo, Seong Jong Park
Clin Exp Pediatr. 2009;52(10):1153-1160.   Published online October 15, 2009
Purpose : To evaluate the risk factors for mortality and prognostic factors in pediatric hemato-oncology patients admitted to the pediatric intensive care unit (PICU). Methods : We retrospectively reviewed the medical records of pediatric hemato-oncology patients admitted at the PICU of the Asan Medical Center between September 2005 and July 2008. Patients admitted at the PICU for perioperative or terminal...
Microbiological spectrum and antibiotic susceptibility pattern in more than 24-month-old children with urinary tract infection: A6-year retrospective, single center experience
Jeong Hee Ko, Jee Hyung Lee, Eun Jung Shim, Do jun Cho, Ki Sik Min, Ki Yang Yoo, Dae Young Lee, Hee Jung Kang
Clin Exp Pediatr. 2009;52(10):1147-1152.   Published online October 15, 2009
Purpose : To characterize the pathogens and their antibiotic susceptibilities in more than 24-month-old children with urinary tract infection (UTI) and to study the Escherichia coli antimicrobial susceptibility trend. Methods : We retrospectively reviewed the record of more than 24-month-old children with UTI between January 2003 and December 2008. Positive results for 1 bacterial species with a colony count of...
Association of ionized magnesium, total magnesium, gestational age, and intraventricular hemorrhage in preterm babies
Tae-Yeon Kim, Hyun-Hee Lee, Tae-Jung Sung
Clin Exp Pediatr. 2009;52(10):1140-1146.   Published online October 15, 2009
Purpose : The pathophysiology of magnesium, the second highest common compound in humans, is still unclear, especially in preterm babies. We accessed the association between total magnesium (tMg), ionized Mg (iMg), and gestational age (GA) and that between serum magnesium (sMg) and intraventricular hemorrhage (IVH) in preterm babies. Methods : In all, 119 inborn preterm infants admitted between July 2006...
Relationship between the depth of cingulate sulcus on neonatal high resolution cranial ultrasound and gestational age
Young Chil Choi, Jin Yong Choi, Jung Hwa Lee
Clin Exp Pediatr. 2009;52(10):1136-1139.   Published online October 15, 2009
Purpose : It is critical that the exact gestational age of a newborn baby, especially premature baby, be determined to evaluate the status of a disease and its management and to estimate the prognosis of a patient. This study aimed to investigate an easy and accurate method to estimate gestational age on cranial ultrasound, requiring minimal additional time and equipment. Methods...
Magnetic resonance imagining findings of the white matter abnormalities in the brain of very-low-birth-weight infants
Jae Hyuk Choi, Young Pyo Chang
Clin Exp Pediatr. 2009;52(10):1127-1135.   Published online October 15, 2009
Purpose : To observe the abnormal white matter findings on the magnetic resonance imaging (MRI) scans of very-low- birth-weight (VLBW) infant brains at term-equivalent age and to determine the clinical risk factors for the development of periventricular leukomalacia (PVL). Methods : In all, MRI was performed in 98 VLBW infants and the white matter abnormalities were observed. Clinical risk factors...
Comparative study of newborns of Asian immigrant and Korean women
Hee-ok Park, Jae-woo Lim, Hyun-seung Jin, Jae-won Shim, Min-hee Kim, Chun-soo Kim, Eun-ryoung Kim, Seung-youn Kim, Sang-kee Park, Jung-joo Lee
Clin Exp Pediatr. 2009;52(10):1119-1126.   Published online October 15, 2009
Purpose : This study compares the maternal characteristics and birth outcomes of infants of Asian immigrant mothers from developing countries with those of the infants of Korean mothers. Methods : In this multicenter and retrospective study, Asian immigrant women who had delivered between January 2005 and June 2008 were enrolled from9 Medical Centers. In all, 333 births to Asian immigrant...
Metabolic syndrome in the overweight and obese adolescents and the impact of obesity on the cardiovascular system
Yong Mi Hong, Young Young Song, Hae Soon Kim, Hae Sook Park, Jung Hae Min, Jo Won Jung, Nam Soo Park, Chung Il Noh
Clin Exp Pediatr. 2009;52(10):1109-1118.   Published online October 15, 2009
Purpose : Metabolic syndrome (MS), characterized by obesity and insulin resistance, elicits risk factors such as hyperlipidemia, hypertension, and glucose intolerance with additive effects on atherosclerosis, leading to cardiovascular diseases. The purposes of this study were to evaluate the prevalence of MS among overweight and obese adolescents and to investigate the impact of obesity on the cardiovascular system. Methods : In...
A study on the utilization of complementary and alternative medicine for elementary children
Young Joon Ahn, Eun Young Kim, Kyung Rye Moon
Clin Exp Pediatr. 2009;52(10):1103-1108.   Published online October 15, 2009
Purpose : Recently, complementary and alternative medicine (CAM) has been increasingly used in children. Studies have shown that 34% of adults and 11% of children use CAM in the USA and Canada. The purpose of this study was to investigate the prevalence and patterns of CAM use in elementary children in Korea. Methods : From July to August 2007, parents...
Current feeding practices and maternal nutritional knowledge on complementary feeding in Korea
Hye Won Yom, Jeong Wan Seo, Hyesook Park, Kwang Hae Choi, Ju Young Chang, Eell Ryoo, Hye Ran Yang, Jae Young Kim, Ji Hyun Seo, Yong Joo Kim, Kyung Rye Moon, Ki Soo Kang, Kie Young Park, Seong Soo Lee, Jeong Ok Shim
Clin Exp Pediatr. 2009;52(10):1090-1102.   Published online October 15, 2009
Purpose : To evaluate current feeding practices and maternal nutritional knowledge on complementary feeding. Methods:Mothers of babies aged 9-15 months who visited pediatric clinics of 14 general hospitals between September and December 2008 were asked to fill questionnaires. Data from 1,078 questionnaires were analyzed. Results : Complementary food was introduced at 4-7 months in 89% of babies. Home-made rice gruel was the...
Remission rate and remission predictors of Graves disease in children and adolescents
Sun Hee Lee, Seong Yong Lee, Hye Rim Chung, Jae Hyun Kim, Ji Hyun Kim, Young Ah Lee, Sei Won Yang, Choong Ho Shin
Clin Exp Pediatr. 2009;52(9):1021-1028.   Published online September 15, 2009
Purpose : Medical therapy is the initial treatment for children with Graves disease to avoid complications of other treatments. However, optimal treatment for childhood Graves disease is controversial because most patients require relatively long periods of medical therapy and relapse is common after medication discontinuation. Therefore, this study aimed to search clinical or biochemical characteristics that could be used as...
Toll-like receptor 9 expression and interferon-α secretion upon CpG-ODN stimulation in allergic subjects
Man Yong Han, Hye Mi Jee, Hyeong Yoon Kim, Cho Ae Lee, Hyo-Jin Cho, Seong-Gyu Hwang, Kyu-Earn Kim
Clin Exp Pediatr. 2009;52(9):1015-1020.   Published online September 15, 2009

Purpose:The aim of this study is to explore the effect of the Toll-like receptor 9 (TLR9) expressed in plasmacytoid dendritic cells (pDCs) that respond to antigen to Th2 immune deviation in allergic patients. Methods:Subjects consisted of 19 allergic patients and 17 healthy volunteers. Skin prick tests and nasal provocation tests were performed for the two groups. Peripheral blood mononuclear cells (PBMCs)...
Mediating effect of perceived stigma against epilepsy on quality of life among parents with epileptic child
Nho Eun Kim, Sung Min Cho, Dong Wook Kim
Clin Exp Pediatr. 2009;52(9):1005-1014.   Published online September 15, 2009

Purpose:Epilepsy of child may cause high level of psychosocial difficulties for parents including stigmatization and stress and therefore worsen their quality of life (QOL). The purpose of this study was to evaluate the mediating effect of perceived stigma against epilepsy on QOL among parents with epileptic child. Methods:Two hundred and sixty parents of epileptic child recruited from five separated university...
Comparison of various methods of glomerular filtration rate measurements in children
Na Mi Lee, In Seok Lim
Clin Exp Pediatr. 2009;52(9):999-1004.   Published online September 15, 2009

Purpose:Glomerular filtration rate (GFR) is a fundamental parameter in assessing renal function and predicting the progression of chronic renal disease. Because the use of serum creatinine has several disadvantages, many studies have investigated the use of cystatin C for estimating GFR. We compared creatinine clearance and GFR with formulas using serum creatinine and cystatin C. Methods:We retrospectively analyzed 211 patients...
Thyroid dysfunction in premature infants
Ki Bae Hong, Ji Yun Park, Young Pyo Chang, Jeesuk Yu
Clin Exp Pediatr. 2009;52(9):991-998.   Published online September 15, 2009

Purpose:Thyroid hormone is essential for development of the brain in early life. Thyroid dysfunction is more common in the first 2-4 postnatal weeks of life in premature infants than in term infants. This study aimed to identify the prevalence and clinical course of thyroid dysfunction in prematurity. Methods:Premature infants admitted to and given neonatal screenings at Dankook University Hospital between...
Catch up growth in children born small for gestational age by corrected growth curve
Myung Ki Jung, Ji Eun Song, Seung Yang, Il Tae Hwang, Hae Ran Lee
Clin Exp Pediatr. 2009;52(9):984-990.   Published online September 15, 2009

Purpose:Being small for gestational age (SGA) is a risk factor of short stature in children. Genetic background such as mid-parental height (MPH) is known to influence growth of children born SGA. We studied the relationship between growth of children born SGA and MPH and studied the effects of insulin-like growth factor (IGF-I) and insulin-like growth factor binding protein 3 (IGFBP-3)...
Effect of angiotensin II inhibition on the epithelial to mesenchymal transition in developing rat kidney
Hyung Eun Yim, Kee Hwan Yoo, In Sun Bae, Young Sook Hong, Joo Won Lee
Clin Exp Pediatr. 2009;52(8):944-952.   Published online August 15, 2009

Purpose:To investigate the effects of angiotensin II inhibition on the epithelial to mesenchymal transition (EMT) in the developing kidney, we tested the expression of EMT markers and nestin in angiotensin converting enzyme (ACE) inhibitor-treated kidneys. Methods:Newborn rat pups were treated with enalapril (30 mg/kg/d) or a vehicle for 7 days. Immunohistochemistry for the expression of α-smooth muscle actin (SMA), E-cadherin, vimentin, and nestin were...
Effect of renin inhibition on an experimental glomerulonephritis - a preliminary report
Ju Hyung Kang, Jae Kyung Huh, Young Sook Lee, Ji Young Han, Il Soo Ha
Clin Exp Pediatr. 2009;52(8):938-943.   Published online August 15, 2009

Purpose:We performed this study in order to investigate the effect of direct renin inhibition on an experimental animal model with nephrotoxic serum nephritis and tried to give useful information for clinical research and renin inhibitor treatment. Methods:Thirty BALB/c 6-week-old male mice were divided into 4 groups: control group (CO, n=5), control-treatment group with aliskiren (CT, n=5), disease group (DO, n=10), and disease treatment...
Comparison and analysis of the effectiveness to high dose of aspirin and ibuprofen in acute phase of Kawasaki disease
Seung-woon Keum, Yeon Kyun Oh, Jong Duck Kim, Seung-taek Yu
Clin Exp Pediatr. 2009;52(8):930-937.   Published online August 15, 2009

Purpose:We evaluated the effectiveness of treatment and cardiac complications of replacing a high dose of aspirin with a high dose of ibuprofen for children in acute phase of Kawasaki disease. We also analyzed the possibility of replacing a high dose of aspirin with a high dose of ibuprofen to prevent complications such as Reye s syndrome caused by aspirin. Methods:One hundred eight children...
Growth responses to growth hormone therapy in children with attenuated growth who showed normal growth hormone response to stimulation tests
Jae Hyun Kim, Hey Rim Chung, Young Ah Lee, Sun Hee Lee, Ji Hyub Kim, Choong Ho Shin, Sei Won Yang
Clin Exp Pediatr. 2009;52(8):922-929.   Published online August 15, 2009

Purpose:The aim was to investigate the clinical characteristics and responses to growth hormone (GH) therapy in children with attenuated growth who showed normal GH responses to GH stimulation tests (GHST). Methods:The study included 39 patients with height velocity (HV) of less than 4 cm/yr and normal GHST results. Clinical characteristics of patients were analyzed retrospectively. Results:Eleven were born as small for gestational age (SGA)...
Clinical study of urinary tract infection, natural courses, and prenatal ultrasonographic results according to the grades of hydronephrosis
Jee-Hee Lee, Jun-Woo Kim, Ji-Eun Yoon, Tae-Sun Ha
Clin Exp Pediatr. 2009;52(8):917-921.   Published online August 15, 2009

Purpose:Although renal ultrasonography (USG) has improved the detection rate of hydronephrosis (HN), its clinical courses and postnatal management remains controversial. Here, we reviewed the clinical features of patients with HN according to the grades. Methods:We retrospectively studied 207 patients who were regularly followed-up among 367 patients with HN detected by renal USG postnatally between April 1998 and December 2007. These patients were grouped...
Outcomes of the arterial switch operation in complete transposition of the great arteries
Min Jung Cho, Ji Ae Park, Hyoung Doo Lee, Si Chan Sung, Ki Seok Choo
Clin Exp Pediatr. 2009;52(8):910-916.   Published online August 15, 2009

Purpose:The arterial switch operation (ASO) has become the preferred procedure for the surgical management of transposition of the great arteries (TGA). We conducted a retrospective evaluation of our experience in 30 patients seen from January 2003 to July 2008, in order to determine outcomes and related risk factors after the arterial switch operation. Methods:Patients charts, surgical reports, and echocardiograms were retrospectively reviewed. And...
Pulmonary tuberculosis misdiagnosed as lung Metastasis in childhood cancer patients
Hyun Rae KK, Dong Whand Lim, Kang Min, Kyung Duk Park, Jun Ah Lee, Soo Yeon Cho, Yoon Hoh Kook, Hee Youn Kim, Dong Ho Kim
Clin Exp Pediatr. 2009;52(8):904-909.   Published online August 15, 2009

Purpose:The differential diagnosis for a pulmonary nodule is intriguing in cancer patients. Metastasis might be a preferential diagnosis, and yet possibilities of other medical conditions still exist. Pulmonary tuberculosis should be enlisted in the differential diagnosis for a pulmonary nodule in cancer patients in Korea. This study was aimed at analyzing the incidence and clinical features of pulmonary tuberculosis that were misdiagnosed as...
Predictive factors for severe infection among febrile infants younger than three months of age
Eun Young Cho, Hwa Song, Ae Suk Kim, Sun Ju Lee, Dong Seok Lee, Doo Kwun Kim, Sung Min Choi, Kwan Lee, Byoung Chan Park
Clin Exp Pediatr. 2009;52(8):898-903.   Published online August 15, 2009

Purpose:This study investigated the predictive factors for identifying infection-prone febrile infants younger than three months. Methods:We conducted a retrospective study of 167 infants younger than three months with an axillary temperature >38℃ who were hospitalized between 2006 and 2008. If they met any of the following criteria, positive blood culture, CSF WBC ≥ 11/mm3 or positive CSF culture, urinalysis WBC ≥6/HPF and positive...
The effects of neonatal ventilator care or maternal chorioamnionitis on the development of bronchopulmonary dysplasia
Ki Tae Yun, Whan Dong Lee, Sang Geel Lee
Clin Exp Pediatr. 2009;52(8):893-897.   Published online August 15, 2009

Purpose:Advances in neonatal intensive care have improved the survival rate of low-birth-weight infants, but mild bronchopulmonary dysplasia (BPD) with the accompanying need for prolonged oxygen supplement remains problematic. Maternal chorioamnionitis and neonatal ventilator care affect the development of BPD. This study aimed to examine whether maternal chorioamnionitis or neonatal ventilator care affect the development of BPD dependently or independently. Methods:We performed a retrospective study...
Readmission of late preterm infants after discharge from nursery
Myo Jing Kim
Clin Exp Pediatr. 2009;52(8):888-892.   Published online August 15, 2009

Purpose:To evaluate the risk factors for hospital readmission during the neonatal period among late preterm infants who were discharged after nursery care. Methods:In this retrospective study, we reviewed medical records of 135 late preterm infants readmitted to the neonatal intensive care unit (NICU) during the neonatal period, after discharge from nursery of IL Sin Christian Hospital from January 2003 to December 2008. We compared...
Changes in the outcomes of neonatal intensive care unit at a single center over 12 years
Hyun-Hee Lee, Tae-Yeon Kim, Seon-Hee Shin, Tae-Jung Sung
Clin Exp Pediatr. 2009;52(8):881-887.   Published online August 15, 2009

Purpose:The survival rate of very low birth weight infant (VLBWI) had increased as a result of advances in neonatal intensive care. We evaluated the changes in outcomes of VLBWI who admitted to the neonatal care unit of Hallym University Kangnam Sacred Heart Hospital. Methods:Retrospective review of 339 VLBWI who were born from 1st January 1997 to 31th December 2008 were performed. Outcomes including survival...
A study on the incidence of anemia according to feeding patterns and the status of weaning diet
Hyun Ji Kim, Mee Yong Shin, Sung Shin Kim, Jae Ock Park, Chang Hwi Kim
Clin Exp Pediatr. 2009;52(8):875-880.   Published online August 15, 2009

Purpose:Iron-deficiency anemia remains the most common nutritional deficiency in young infants. This study aimed to survey the actual condition of feeding patterns and weaning diet and to study the association between these factors and the prevalence of anemia in infants aged over 9 months. Methods:We studied 171 infants aged 9-24 months who were hospitalized in the general ward with mild to moderate acute illnesses....
Short-lasting headaches in children and adolescents
Young-il Rho
Clin Exp Pediatr. 2009;52(8):869-874.   Published online August 15, 2009

Purpose:Short attacks of headache are present in the pediatric age group. Short-lasting headaches (SLH) have been infrequently reported in children and adolescents. This study aims to assess the prevalence, clinical characteristics, treatment, and prognosis of short-lasting headaches in children and adolescents. Methods:One hundred twenty-three consecutive patients attended the Chosun University Hospital Headache Center between March 2006 and July 2007. Among 123 headache patients, 44...
Functional recovery after transplantation of mouse bone marrow-derived mesenchymal stem cells for hypoxic-ischemic brain injury in immature rats
Wooksun Choi, Hye Kyung Shin, So-Hee Eun, Hoon Chul Kang, Sung Won Park, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Baik-Lin Eun
Clin Exp Pediatr. 2009;52(7):824-831.   Published online July 15, 2009
Purpose : We aimed to investigate the efficacy of and functional recovery after intracerebral transplantation of different doses of mouse mesenchymal stem cells (mMSCs) in immature rat brain with hypoxic-ischemic encephalopathy (HIE). Methods : Postnatal 7-days-old Sprague-Dawley rats, which had undergone unilateral HI operation, were given stereotaxic intracerebral injections of either vehicle or mMSCs and then tested for locomotory activity in...
A study of the frequency and characteristics of minor clinical manifestations in children with atopic dermatitis
Ji Eun Cho, You Hoon Jeon, Hyeon Jong Yang, Bok Yang Pyun
Clin Exp Pediatr. 2009;52(7):818-823.   Published online July 15, 2009
Purpose : We aimed to evaluate the frequency and characteristics of minor clinical manifestations of atopic dermatitis (AD) in Korean children to aid the diagnosis and treatment of AD. Methods : From April 2007 to December 2007, we enrolled 106 children (aged 1 month [infants] to 15 years) diagnosed with AD at the Pediatric Allergy Respiratory Center in Soonchunhyang University Hospital....
TOPICS

Browse all articles >

ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
FOR CONTRIBUTORS
ABOUT
Editorial Office
Korean Pediatric Society
#1606 Seocho World Officetel, 19 Seoun-ro, Seocho-ku, Seoul 06732, Korea
Tel: +82-2-3473-7306    Fax: +82-2-3473-7307    E-mail: office@e-cep.org                

Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)

Copyright © 2026 by Korean Pediatric Society.      Developed in M2PI