- Review Article
- Endocrinology
- Hidden link between endocrine-disrupting chemicals and pediatric obesity
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Min Won Shin, Shin-Hye Kim
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Clin Exp Pediatr. 2025;68(3):199-222. Published online November 28, 2024
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Studies indicate potential connections between exposure to endocrine-disrupting chemicals (EDCs) and childhood obesity. Variations in the impact of EDCs in epidemiological studies may result from differences in exposure concentrations and timing, measurement methods, and interactive effects of multiple EDCs. Longitudinal studies on exposure to multiple EDCs are crucial to elucidating their contribution to pediatric obesity and minimize the adverse health consequences of EDC exposure. |
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- Air pollution and childhood obesity
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Moon Young Seo, Shin-Hye Kim, Mi Jung Park
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Clin Exp Pediatr. 2020;63(10):382-388. Published online March 27, 2020
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Questions: What are the possible effects of air pollution on the occurrence of childhood obesity and what are the mechanisms?
Finding: Epidemiologic studies suggest that air pollutants might act as obesogens in the pediatric population, and their possible mechanisms include oxidative stress, physical inactivity, and epigenetic modulation.
Meaning: This paper reviews updated information on air pollution, one of the modifiable environmental factors in childhood obesity. |
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- The relationship between leptin adiponectin ratio and
insulin resistance in healthy children
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Gae-Hyun Ahn, Shin-Hye Kim, Eun-Gyong Yoo
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Clin Exp Pediatr. 2008;51(3):256-261. Published online March 15, 2008
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Purpose : Leptin and adiponectin are two representative adipocytokines. Leptin increases, but adiponectin decreases, with obesity and insulin resistance. We aimed to study the relationship between the leptin/adiponectin ratio and insulin resistance in healthy children.
Methods : Seventy-seven healthy children (36 boys and 41 girls) were enrolled in this study. Anthropometric measurements were performed, and the percentage of weight for... |
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- Correlation of serum total hydroperoxide levels and diseases of prematurity
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Shin-Hye Kim, Hae Young Hur, Kyu Hyoung Lee, Ja Young Moon, Kyu Young Chae
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Clin Exp Pediatr. 2007;50(8):746-751. Published online August 15, 2007
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Purpose : Total hydroperoxide (TH), free radical-mediated oxidation product can be used as a measure of free radical injury. The aim of the present study was to see if preterm newborns are at increased risk for oxidative stress compared with term newborns, and to determine whether oxidative stress during postnatal first 1 week is associated with clinical outcomes in preterm... |
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