- Review Article
- Current issues of pediatric inflammatory bowel disease in Korea
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Seak Hee Oh, Kyung Mo Kim
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Clin Exp Pediatr. 2014;57(11):465-471. Published online November 30, 2014
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Inflammatory bowel disease (IBD) is a chronic relapsing disorder of unknown etiology, which is believed to be multifactorial. Recently, the incidence of pediatric IBD has steeply increased in Korea since 2000. Poorly controlled disease activity can result in complications such as intestinal fistulae, abscess, and stricture, as well as growth retardation and delayed puberty in children. Because of a lack... |
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- Case Report
- Liver transplantation in a child with acute liver failure resulting from drug rash with eosinophilia and systemic symptoms syndrome
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Seung Min Song, Min Sung Cho, Seak Hee Oh, Kyung Mo Kim, Young Seo Park, Dae Yeon Kim, Sung Gyu Lee
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Clin Exp Pediatr. 2013;56(5):224-226. Published online May 28, 2013
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Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by a severe idiosyncratic reaction including rash and fever, often with associated hepatitis, arthralgias, lymph node enlargement, or hematologic abnormalities. The mortality rate is approximately 10%, primarily owing to liver failure with massive or multiple disseminated focal necrosis. Here, we report a case of a 14-year-old girl treated with... |
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- Review Article
- Acute liver failure in children
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Kyung Mo Kim
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Clin Exp Pediatr. 2007;50(9):841-847. Published online September 15, 2007
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Acute liver failure (ALF) is a very rare but devastating illness in children. Specific treatment to recovery is often not available, and the underlying cause of the liver failure is often unknown and diverse especially in children. Liver transplantation has increased the chance of survival; however it needs an optimal timing to reach the best result which is not familiar... |
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- Original Article
- Jagged1 mutation analysis in Alagille syndrome patients
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Jae Sung Ko, Hye Ran Yang, Kyung Mo Kim, Jeong Kee Seo
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Clin Exp Pediatr. 2006;49(5):519-522. Published online May 15, 2006
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Purpose : Alagille syndrome is an autosomal dominant disorder with developmental abnormalities affecting the liver, heart, eyes, vertebrae, and craniofacial region. The Jagged1(JAG1) gene, which encodes a ligand of Notch, has been found mutated in Alagille syndrome. The aim of the study was to investigate the mutation analysis of JAG1 gene in Korean patients with Alagille syndrome.
Methods : Genomic DNA... |
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- Case Report
- A Case of Moyamoya Disease in a Child with Alagille Syndrome
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Mi Rang Lim, So Yaun Lee, Deok Soo Kim, Kyung Mo Kim, Tae Sung Ko
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Clin Exp Pediatr. 2003;46(1):86-90. Published online January 15, 2003
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Alagille syndrome is a autosomal dominant disorder characterized by intrahepatic bile duct paucity and resultant chronic cholestasis in combination with cardiac(mainly peripheral pulmonary stenosis), skeletal, ocular, and facial abnormalities. In addition to the pulmonary stenosis, in large series, anecdotal reports of vascular lesions have concerned the renal artery, aorta, hepatic artery, carotid artery, celiac artery or subclavian artery. Theses diffuse... |
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- An Infant with Vertical Transmission of Human Immunodeficiency Virus Infection Detected Due to Failure to Thrive
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Byung Wook Eun, Ho Kyung Lim, Yun Kyung Kim, Yuong Ho Kwak, Jung Youn Hong, He Sun Jung, Kyung Mo Kim, Hoan Jong Lee
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Clin Exp Pediatr. 2001;44(5):592-596. Published online May 15, 2001
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Five to fifteen percent of patients affected by human immunodeficiency virus(HIV) are children in developing countries. In Korea, most of HIV infections in children have been transfusion-related, and cases of vertical transmission have been very rare so far and are usually suspected due to a maternal positive history. We experienced a case of vertical transmission of HIV in a 19... |
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- Original Article
- Analysis of Malnutrition in Children with Congenital Heart Disease
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Jeoung Eun Kim, Bo Hwa Choi, Kyung Mo Kim, Jae Kon Ko, Dong Man Seo
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Clin Exp Pediatr. 2001;44(2):161-166. Published online February 15, 2001
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Purpose : Malnutrition and failure to thrive have long been recognized as common systemic consequences of congenital heart disease(CHD). But there is little data about the prevalence and severity of malnutrition with CHD in Korea. We designed this study to determine the prevalence of malnutrition among hospitalized children with CHD.
Methods : We reviewed 100 hospitalized children with CHD who were... |
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- Factors Predictive of Response to Interferon-α Therapy in
Children with Chronic Hepatitis B
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Hong Kwon Kim, Bo Hwa Choi, Kyung Mo Kim, Kyung Hoon Kang, In Seok Lim, Eung Sang Choi
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Clin Exp Pediatr. 2000;43(4):514-519. Published online April 15, 2000
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Purpose : The efficacy and safety of interferon-alpha(IFN-α) therapy in children with chronic hepatitis B(CHB) is similar to that of adults. However, little information is available about the predictive factors of response to this therapy in children. The aim of this study was to determine the predictive factors for responsiveness to IFN-α therapy in children with CHB.
Methods : The basal... |
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- Effect of Liver Transplantation in Children with Fulminant Hepatitis
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Young Mee Seo, Bo Hwa Choi, Kyung Mo Kim, Kwang Min Park, Young Joo Lee, Sung Gyu Lee
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Clin Exp Pediatr. 2000;43(4):535-542. Published online April 15, 2000
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Purpose : Liver transplantation(LT) is regarded as an important management option for fulminant hepatitis(FH), which is associated with considerable mortality under conservative management. The aim of this study was to evaluate the outcome of children with FH according to management.
Methods : We reviewed medical records of patients presented with FH from January 1994 until April 1999. The children were... |
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- A Case of Ceftriaxone-induced Pseudocholelithiasis
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Hong Kwon Kim, Jeong Ho Kim, Kyung Mo Kim, Chong Hyun Yoon
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Clin Exp Pediatr. 1998;41(6):841-843. Published online June 15, 1998
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Ceftriaxone, a third-generation cephalosporin, is a very potent, broad spectrum antibiotic commonly used in patients with meningitis, osteomyelitis, pyelonephritis, Lyme disease and many other severe infectious diseases. Up to 46% of those receiving this antibiotic develop gallbladder sludge. Most of them are asymptomatic, but a small proportion may develop right upper quadrant pain, nausea, vomiting and even cholecystitis. We report... |
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- Original Article
- Living Related Donor Liver Transplantation in Children : Indication and Clinical Outcome
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Kyung Mo Kim, Sung gyu Lee, Young Joo Lee, Kwang Min Park, Seong Chul Kim, Hoon Bae Chun, Eun Sil Yoo, Sang Hoon Han, Kyung Suk Ko, Mon Gyu Lee, Kyu Taek Choi, Jae Kon Ko, Hyung Nam Moon
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Clin Exp Pediatr. 1998;41(5):622-632. Published online May 15, 1998
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- A Clinical and Histological Study of Allergic Colitis in Infant
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Jae Bok Kim, Kyung Mo Kim, Ki Soo Kim, Soo Young Pi, Yang Soon Park
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Clin Exp Pediatr. 1998;41(4):521-528. Published online April 15, 1998
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Purpose : This study was done to evaluate the clinical and pathologic aspects of allergic colitis.
Methods : This study evaluated 19 infants who presented with fresh blood mixed stools. Limited
colonoscopy and biopsy were performed. Among the 19 infants, 13 infants were diagnosed as
allergic colitis by histological findings. We analyzed the clinical and histological characteristics of
13 infants.
Results : Male and female... |
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- Diagnostic and Therapeutic Efficacy of Endoscopic Retrograde
Cholangiopancreatography in Children
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Kyung Mo Kim, Ho Soon Choi, Sung Koo Lee, Myung Hwan Kim, Chong Hyun Yoon, Dong Myung Lee
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Clin Exp Pediatr. 1997;40(12):1681-1691. Published online December 15, 1997
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Purpose : Endoscopic retrograde cholangiopancreatography(ERCP) may provide more definite
diagnosis, preoperative guidance, and endoscopic therapy in many children with known or suspected
disorders of the pancreas and biliary tract. But the reports about the ERCP in children are rare, so
this study is conducted to evaluate the indication, efficacy and safety of the ERCP in children.
Methods : Twenty nine ERCPs in 19 children... |
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- Influence of Feeding and State of Alertness on the Incidence of Gastroesophageal Reflux in Children
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Kyung Mo Kim, Jung Yeon Shim, Soo Jong Hong
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Clin Exp Pediatr. 1997;40(10):1419-1426. Published online October 15, 1997
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Purpose : The aim of this study is to evaluate the influence of the feeding (fastingpostprandial)
and the state of alertness(awake-asleep) on the amount of gastroesophageal
reflux by using 24hour esophageal pH metry.
Methods : From July 1994 to June 1995, 32 cases of 24 hour esophageal pH metry had
been done at the Asan Medical Center. Twenty three children with normal pH monitoring
and... |
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- Immunologic Changes of Peripheral Blood Lymphocytes in Kawasaki Disease after Intravenous Gamma Globulin Therapy
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Jung Yeon Shim, Kyung Mo Kim, Young Hwue Kim, Soo-Jong Hong
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Clin Exp Pediatr. 1996;39(5):712-721. Published online May 15, 1996
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Purpose : Kawasaki disease(KD) is multi-systemic vasculitis and coronary artery
abnormalities can develop up to 30 percent in untreated patients. Several observations suggest that immune activation and the secretion of cytokines from immune effector cells contribute to the pathogenesis of this disease. Though high dose intravenous gamma globulin(IVGG,>1 gm/kg) is effective in reducing the prevalence of coronary artery aneurysms in KD,... |
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- Clinical and Histologic Changes in Children with Chronic Hepatitis B Virus Infection after Alpha Interferon Therapy
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Kyung Mo Kim, Soo Jong Hong, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Joo Ryoung Huh
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Clin Exp Pediatr. 1995;38(9):1232-1241. Published online September 15, 1995
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Purpose : Several trials in children for chronic hepatitis B have shown the efficacy of alpha interferon in eliminating hepatitis B virus replication, accompanied by an improvement in the liver cell damage. But reports about the alpha interferon therapy are rare in Korean children and there is no report about histologic changes even with adult. So we tried to... |
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- Ischemic Hepatitis in Children after Cardiac Operation -Analysis of Clinical Characteristics, Risk Factors and Outcome-
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Kyung Mo Kim, Jeong Kee Seo
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Clin Exp Pediatr. 1995;38(11):1540-1546. Published online November 15, 1995
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Purpose : We have experienced frequently the ischemic hepatitis after cardiac operations which shows rapid striking rise of transaminase. But the ischemic hepatitis in children after cardiac operation is not defined yet in Korea. We examined the clinical characteristics and analyzed the risk factors and outcome in 20 children who showed typical clinical course of ischemic hepatitis after cardiac operation.
Methods... |
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- Statistical Analysis of Patients in Seoul National University Children's Hospital (1985~1988).
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Kyung Mo Kim, Kwang Wook Ko
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Clin Exp Pediatr. 1990;33(6):744-753. Published online June 30, 1990
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Statistical analysis of outpatients and inpatients from 1985 to 1988 was assessed with aims to have
an overal grasp of patterns and trends of childhood diseases at Seoul National University Children,
s Hospital.
1) Number of outpatient visits were totally 458,390 with annual number of visits of 144,754 and
average daily number of 461, including 241 visits in Department of Pediatrics.
2) Number of patients at Eemergency... |
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- Hypophosphatemic Rickets.
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Kyung Mo Kim, Seong Hoon Ha, Dong Kyu Jin, Kwang Wook Ko
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Clin Exp Pediatr. 1990;33(4):437-447. Published online April 30, 1990
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Seventeen patients who were diagnosed as primary hypophosphatemic rickets at Department of
Pediatrics, Seoul National University Children’s Hospital were analyzed to assess its clinical aspect
and effect of treatment, especially on height and growth velosity.
The average age of onset was 2 years, and their chief complaints were bowleg and short stature.
Sex ratio was l.l:l(male: female). Familial hypophoshatemic rickets was known as X-linked... |
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- Manometric Response to Heller's Myotomy in Achalasia.
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Chun Wha Lee, Kyung Mo Kim, Jeong Kee Seo, Hyung Ro Moon, Joo Hyun Kim
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Clin Exp Pediatr. 1989;32(1):101-108. Published online January 31, 1989
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Achalasia is an espohageal motility disorder. It is characterized by the loss LES relaxation on
swallowing and of esophageal peristalsis and results in dysphagia, regurgitation and substernal pain.
Manometry is one of several diagnostic tests of achalasia and reveals
1) Complete absence of esophageal peristalsis,
2) hypertension of LES. 3) impaired sphincter relaxation on swallowing and 4) positive esophageal
body pressure compared to intragastric pressure.
We... |
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